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  • 1
    Online Resource
    Online Resource
    Wamena Arabica Coffee (Coffea Arabica) Bean Extract Cream Inhibits The Increase Of Tyrosynase And Melanin Levels In Guinea Pig (Cavia Porcellus) Exposed To UVB Lights
    International Journal of Scientific Advances ; 2023
    In:  International Journal Of Scientific Advances Vol. 4, No. 4 ( 2023)
    Details
    In: International Journal Of Scientific Advances, International Journal of Scientific Advances, Vol. 4, No. 4 ( 2023)
    Abstract: Introduction: Most of the aging process in the skin occurs due to exposure to sunlight, especially UV-B light, resulting in an increase in the activity of the tyrosinase enzyme and the amount of melanin which will cause hyperpigmentation of the skin. Antioxidants are substances that can provide protection from endogenous and exogenous oxidative stress by free radicals. The purpose of this study was to prove that Wamena roasted Arabica coffee bean extract cream can inhibit the enzymes tyrosinase and melanin in guinea pig exposed to UV-B lights. Methods: The design of this study was an animal experimental design with a randomized post-test only control group. The subjects of the study were 30 guinea pigs divided into 3 groups: group 1 as control, group 2 with placebo cream and group 3 was with 3% Wamena arabica coffee bean extract cream. The group 2 and 3 were exposed to UV-B light for 2 weeks. The skin of the guinea pig was excised for examination of the levels of the enzymes tyrosinase and melanin. Result: The average tyrosinase and melanin levels in control group were 19.891% and 4.62%, treatment group 2 was an average of 42.699% and 9.26% and treatment group 3 was 23.886% and 4.87%. Conclusion: Arabica coffee (Coffea arabica) bean extract cream roasted Wamena 3% inhibits the tyrosinase enzyme levels and inhibits the melanin in guinea pigs (Cavia porcellus) which are exposed to ultraviolet B light.
    Type of Medium: Online Resource
    ISSN: 2708-7972
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.51542/ijscia.v4i4
    DOI: 10.51542/ijscia
    DOI: 10.51542/ijscia.v4i4.1
    Language: Unknown
    Publisher: International Journal of Scientific Advances
    Publication Date: 2023
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  • 2
    Online Resource
    Online Resource
    CORED (CHRONIC-RELAPSING DEPRESSION) PREVENTION: PENDEKATAN NOVEL BERBASIS APLIKASI SELULER PADA PASIEN GANGGUAN DEPRESI
    Universitas Udayana ; 2021
    In:  Essential: Essence of Scientific Medical Journal Vol. 18, No. 2 ( 2021-02-01), p. 20-
    Details
    In: Essential: Essence of Scientific Medical Journal, Universitas Udayana, Vol. 18, No. 2 ( 2021-02-01), p. 20-
    Abstract: ABSTRACT Introduction: Depressive disorder is a mood disorder that can have a serious impact on a person's life, both in health and in society. This disorder also has a risk of recurrence so that it can have an impact towards chronic depression. Therefore, a novel therapeutic approach is needed to reduce this burden and improve the quality of life of patients previously diagnosed with depressive disorders. Implementation of mobile applications can be an option to mitigate this. This study aims to review cellular application therapy approaches to prevent progression and recurrence in depressive symptoms. Discussion: Efforts to prevent progression and recurrence from depressive disorders can be done through the CORED (Chronic-Relapsing Depression) Prevention mobile application which focuses on: (1) Follow Up, (2) Time management assistance, (3) Meditation and mindfulness training, and (4) Group-Therapy services. The interventions on these four things have good clinical effects to prevent recurrence in depressive patients. In addition, given the high risk of relapse in depression, this application is equipped with Patient Health Questionnaire-9 (PHQ-9) as a screening tool to detect warning signs, in which patients must return to therapy in clinical settings. Conclusion: The use of the application, based on the right principles, is expected to provide maximum effect and can be both effective in terms of time and cost. Further research needs to be carried out to examine the implementation of more integrated applications to assess the effectiveness of the use of cellular applications as prevention of recurrence and chronic depression in depressive disorders patients.
    Type of Medium: Online Resource
    ISSN: 2655-6472 , 1979-0147
    URL: Issue
    URL: Article
    DOI: 10.24843/ESTL.2020.v18.i02
    DOI: 10.24843/ESTL.2020.v18.i02.p03
    Language: Unknown
    Publisher: Universitas Udayana
    Publication Date: 2021
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  • 3
    Online Resource
    Online Resource
    EFFECTIVENESS OF FRUIT JUICE AS COMPLEMENTARY THERAPY ON BLOOD PRESSURE OF HYPERTENSION PATIENTS : A SYSTEMATIC REVIEW OF RANDOMIZED CONTROLLED TRIALS
    Universitas Udayana ; 2022
    In:  E-Jurnal Medika Udayana Vol. 11, No. 9 ( 2022-09-27), p. 89-
    Details
    In: E-Jurnal Medika Udayana, Universitas Udayana, Vol. 11, No. 9 ( 2022-09-27), p. 89-
    Abstract: Hypertension treatment can be helped through complementary therapies, one of which is fruit juices. This study aimed to systematically review the evidence from various study regarding the effect of fruit juices on blood pressure in hypertensive patients and the types of fruit juices that are proven to be effective in reducing hypertension.This study is systematic review. Literature searching was conducted in four electronic databases, namely CINAHL, EMBASE, Pubmed, and Sciencedirect with the phrase fruit juices AND (hypertension OR blood pressure). Studies obtained from searching will be selected based on a screening title and abstract, eligibility criteria, and assesment risk of bias. The results of the study obtained 21 final studies with RCT research designs that passed the screening with complete eligibility criteria. However, the studies with valid results only amounted to 8 studies. These data show that as many as 5 studies prove fruit juices can reduce blood pressure in hypertensive patients and 3 other studies have stated the opposite. Thus, it can be concluded that there is strong evidence that fruit juices has a significant effect on reducing blood pressure in hypertensive patients. Fruit juices that have been shown to be effective are orange juice and queen garnet plum juice
    Type of Medium: Online Resource
    ISSN: 2303-1395
    URL: Article
    DOI: 10.24843/MU.2022.V11.i9.P17
    Language: Unknown
    Publisher: Universitas Udayana
    Publication Date: 2022
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  • 4
    Online Resource
    Online Resource
    HUBUNGAN WAIST TO HEIGHT RATIO DAN TEKANAN DARAH PADA ANAK SEKOLAH DASAR KELAS 4-6 DI DENPASAR TIMUR
    Universitas Udayana ; 2022
    In:  Majalah Ilmiah Fisioterapi Indonesia Vol. 10, No. 1 ( 2022-01-25), p. 1-
    Details
    In: Majalah Ilmiah Fisioterapi Indonesia, Universitas Udayana, Vol. 10, No. 1 ( 2022-01-25), p. 1-
    Abstract: Pendahuluan: Obesitas merupakan keadaan patologi akibat dari mengkonsumsi makanan berlebih sehingga terjadi penumpukkan lemak yang berlebihan dan merupakan salah satu faktor risiko terjadinya tekanan darah tinggi atau hipertensi. Hipertensi anak menjadi suatu keadaan yang memprihatinkan karena dapat menyebabkan kerusakan di organ tubuh. Waist to Height Ratio adalah pengukuran antropometrik yang baik digunakan untuk mendeteksi faktor risiko penyakit kardiovaskular pada subjek dengan obesitas jika dibandingkan BMI, waist to hip ratio (WHR), waist circumference karena mampu diaplikasikan tanpa membedakan gender, ras dan etnik tertentu. Penelitian ini memiliki tujuan yaitu mengetahui hubungan lingkar pinggang dan tekanan darah pada anak sekolah dasar kelas 4-6 di Denpasar Timur.Metode: Rancangan penelitian yang digunakan yaitu observasional analitik, menggunakan metode pendekatan studi cross sectional, serta teknik sampel purposive sampling dalam pengambilan sampel. Sampel berjumlah 67 orang, yang diukur tekanan darahnya dengan tensimeter dan Waist to Height ratio (WHtR) menggunakan rumus lingkar pinggang (cm) dibagi dengan tinggi badan (cm).Hasil: Berdasarkan uji analisis data dengan menggunakan chi-square untuk mengetahui hubungan waist to height ratio dan tekanan darah sistolik dan diastolik diperoleh nilai p=0,000 (p 〈 0,05).Simpulan: ada hubungan antara waist to height ratio dan tekanan darah pada anak sekolah dasar kelas 4-6 di Denpasar Timur. Kata Kunci: obesitas, tekanan darah, WHtR
    Type of Medium: Online Resource
    ISSN: 2722-0443 , 2303-1921
    URL: Issue
    URL: Article
    DOI: 10.24843/MIFI.2022.v10.i01
    DOI: 10.24843/MIFI.2022.v10.i01.p01
    Language: Unknown
    Publisher: Universitas Udayana
    Publication Date: 2022
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  • 5
    Online Resource
    Online Resource
    Anti-proliperative and Anti-metastatic Agents of Balinese Long Pepper (Piper retrofractum V) Extract in Breast Cancer
    Fakultas Sains dan Teknologi UINSA ; 2020
    In:  Journal of Health Science and Prevention Vol. 4, No. 1 ( 2020-04-01), p. 1-6
    Details
    In: Journal of Health Science and Prevention, Fakultas Sains dan Teknologi UINSA, Vol. 4, No. 1 ( 2020-04-01), p. 1-6
    Abstract: Breast cancer is malignancy that becomes significant health problem in the world. According to WHO data in 2018, there were 2.1 million cases of breast cancer with mortality rate reaching 627,000. Current breast cancer treatments are surgery, radiation therapy, hormonal therapy and chemotherapy. However, these treatments have side effects such as neuropathy, fatigue after undergoing chemotherapy, and alopecia. Natural ingredients are the choice to overcome these weaknesses, one of which is the utilization of piperine in Balinese long pepper (Piper retrofractum Vahl). Piperine can increase the bioavailability of many drugs by increasing absorption from the intestine, suppressing the metabolism of drugs in lung and liver tissue by inhibiting CYP3A4 and P84 glycoprotein P84. Piperine is easily absorbed in the intestine and excreted through urine and feces, causing minimal toxic effects. Piperine in Balinese long pepper is able to reduce breast cancer cell proliferation by 40%. Piperine can also inhibit epidermal growth factor (EGF) by inducing decreased expression of MMP-9 and MMP-13. Piperine will work through inhibition of NF-κB and PKCα phosphorylation and AP-1 activation by interfering extracellular signal-regulated kinase (ERK) signaling pathway (ERK) 1/2, p38 MAPK, and Akt which results in inhibition of migration and metastasis of breast cancer cells. Keyword: Anti-metastatic, Anti-proliferative, Breast Cancer, Piperine, Piper Retrofractum.  
    Type of Medium: Online Resource
    ISSN: 2549-919X
    URL: Issue
    URL: Article
    DOI: 10.29080/jhsp.v4i1
    DOI: 10.29080/jhsp.v4i1.258
    Language: Unknown
    Publisher: Fakultas Sains dan Teknologi UINSA
    Publication Date: 2020
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  • 6
    Online Resource
    Online Resource
    Relationship between leg muscle explosive power and lay-up shoot ability
    Sanglah Hospital - Udayana University ; 2023
    In:  Physical Therapy Journal of Indonesia Vol. 5, No. 1 ( 2023-12-25), p. 5-8
    Details
    In: Physical Therapy Journal of Indonesia, Sanglah Hospital - Udayana University, Vol. 5, No. 1 ( 2023-12-25), p. 5-8
    Abstract: Background: Lay-up shoot is one of the basic techniques that a basketball athlete must master to be a winner. The shooting technique involves jumping and dribbling the ball as close as possible into the ring. This study aimed to describe the relationship between leg muscle explosive power and lay-up shoot ability. Methods: This research was a descriptive study with a correlational design that used a total sampling technique that targeted all students who were basketball club members at Public Senior High School 8 Denpasar concerning inclusion and exclusion criteria. A vertical jump test measured leg muscle explosive power, and the lay-up shoot ability was measured by doing a lay-up shoot ten times. Results: The results showed a relationship between leg muscle explosive power and the lay-up shoot ability of the students. Most students have above-average legs, muscle explosive power, and good lay-up shooting skills. The better the leg's muscle explosive power, the better the lay-up shoot ability, which shows that the leg muscle explosive power is positively correlated with the lay-up shoot ability Conclusion: This study found a significant relationship between leg muscle explosive power and ability lay-up shoot students at the basketball club Public Senior High School 8 Denpasar.
    Type of Medium: Online Resource
    ISSN: 2722-6034 , 2722-0125
    URL: Issue
    URL: Article
    DOI: 10.51559/ptji.v5i1
    DOI: 10.51559/ptji.v5i1.168
    Language: Unknown
    Publisher: Sanglah Hospital - Udayana University
    Publication Date: 2023
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  • 7
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    Online Resource
    Exposure to particulate matter (PM2.5) and prevalence of diabetes mellitus in Indonesia
    Elsevier BV ; 2020
    In:  Environment International Vol. 140 ( 2020-07), p. 105603-
    Details
    In: Environment International, Elsevier BV, Vol. 140 ( 2020-07), p. 105603-
    Type of Medium: Online Resource
    ISSN: 0160-4120
    URL: Article
    DOI: 10.1016/j.envint.2020.105603
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2020
    detail.hit.zdb_id: 554791-X
    detail.hit.zdb_id: 1497569-5
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  • 8
    Online Resource
    Online Resource
    THE RELATIONSHIP BETWEEN BALANCE AND FLEXIBILITY WITH ABILITY OF DOLLYO CHAGI KICK IN TAEKWONDO ATHLETES IN DENPASAR
    Universitas Udayana ; 2021
    In:  Majalah Ilmiah Fisioterapi Indonesia Vol. 9, No. 2 ( 2021-05-13), p. 94-
    Details
    In: Majalah Ilmiah Fisioterapi Indonesia, Universitas Udayana, Vol. 9, No. 2 ( 2021-05-13), p. 94-
    Abstract: Taekwondo is one of the popular martial arts for the young, teenagers, and adults. One of the kicks that are often used and effective to attack opponents in a match is the Dollyo Chagi kick. Balance and flexibility have an important role in creating optimal kick. To determine the relationship between balance and flexibility with ability of dollyo chagi kick in taekwondo athletes in Denpasar. This study was an observational study using a cross sectional design. The study was conducted 4 days at 4 dojang in Denpasar. Sampling was carried out using the cluster random sampling, with a total of 64 subjects participating in 12-16 years. Based on the Spearman rho non parametric analysis test obtained a weak and significant relationship between balance with the ability of dollyo chagi kick, with a value of p=0.034 (p 〈 0.05), and also obtained a moderate and significant relationship between flexibility with the dollyo chagi kick ability, with a value of p=0.008 (p 〈 0.05). Multiple linear regression analysis test was conducted to determine the relationship of balance and fleksibility with the dollyo chagi kick ability and obtain a value of p=0.001 (p 〈 0.05) and a correlation value (R) of 0.469. Keyword: dollyo chagi kick, balance, flexibility.
    Type of Medium: Online Resource
    ISSN: 2722-0443 , 2303-1921
    URL: Issue
    URL: Article
    DOI: 10.24843/MIFI.2021.v09.i02
    DOI: 10.24843/MIFI.2021.v09.i02.p06
    Language: Unknown
    Publisher: Universitas Udayana
    Publication Date: 2021
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  • 9
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    Online Resource
    Exposure of Ambient PM2.5 and Acute Upper-and Lower Respiratory Infection in Children Under the Age of Five in South and Southeast Asia
    IOS Press ; 2023
    In:  Asian Journal of Water, Environment and Pollution Vol. 20, No. 2 ( 2023-03-29), p. 41-49
    Details
    In: Asian Journal of Water, Environment and Pollution, IOS Press, Vol. 20, No. 2 ( 2023-03-29), p. 41-49
    Abstract: Studies on ambient PM2.5 exposure and AURI and ALRI in regions such as South and South-East Asia, where levels of PM2.5 are among the highest, are limited. We assessed the associations between ambient PM2.5 exposure and AURI and ALRI in children under the age of 5 years from South and Southeast Asia. We identified subjects from the demographic health survey (DHS). We retrieved PM2.5 information from the Atmospheric Compositional Analysis Group. Annual mean levels of PM2.5 ranged from 21.3 to 73.2 μg/m3. We performed the meta-analytical approach to obtain the pooled results. Our initial results show an association between ambient PM2.5 exposure and AURI (OR 1.06, 95% CI: 1.01-1.11) but not ALRI (OR 1.03, 95% CI: 0.98-1.09). However, after controlling for indoor SHS, effect estimates became stronger for AURI and ALRI (OR 1.27, 95% CI: 1.04-1.54 and OR 1.20, 95% CI: 1.00-1.44) compared to the uncontrolled group. Our study shows an association between ambient PM2.5 exposure and the prevalence of AURI and ALRI in children under the age of 5 years from South and Southeast Asia. Promoting awareness of air pollution in line with the implementation and monitoring of relevant policies is crucial in establishing clean air and health.
    Type of Medium: Online Resource
    ISSN: 0972-9860 , 1875-8568
    URL: Article
    DOI: 10.3233/AJW230023
    Language: Unknown
    Publisher: IOS Press
    Publication Date: 2023
    detail.hit.zdb_id: 2167739-6
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  • 10
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    Oral Administration of Moringa (Moringa oleifera) Leaf Ethanol Extract Reduces Interleukin-6 (IL-6) and Tumor Necrosis Factor-α (TNF-α) Levels of Obese Wistar Rats
    Genesis Global Publication ; 2023
    In:  International Journal of Research Publication and Reviews Vol. 4, No. 6 ( 2023-06-23), p. 4243-4248
    Details
    In: International Journal of Research Publication and Reviews, Genesis Global Publication, Vol. 4, No. 6 ( 2023-06-23), p. 4243-4248
    Type of Medium: Online Resource
    ISSN: 2582-7421
    Uniform Title: Oral Administration of Moringa (Moringa oleifera) Leaf Ethanol Extract Reduces Interleukin-6 (IL-6) and Tumor Necrosis Factor-α (TNF-α) Levels of Obese Wistar Rats
    URL: Journal
    URL: Article
    DOI: 10.55248/gengpi
    DOI: 10.55248/gengpi.4.623.47449
    Language: Unknown
    Publisher: Genesis Global Publication
    Publication Date: 2023
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