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  • 1
    Online Resource
    Online Resource
    Identical and Nonidentical Twins: Risk and Factors Involved in Development of Islet Autoimmunity and Type 1 Diabetes
    American Diabetes Association ; 2019
    In:  Diabetes Care Vol. 42, No. 2 ( 2019-02-01), p. 192-199
    Details
    In: Diabetes Care, American Diabetes Association, Vol. 42, No. 2 ( 2019-02-01), p. 192-199
    Abstract: There are variable reports of risk of concordance for progression to islet autoantibodies and type 1 diabetes in identical twins after one twin is diagnosed. We examined development of positive autoantibodies and type 1 diabetes and the effects of genetic factors and common environment on autoantibody positivity in identical twins, nonidentical twins, and full siblings. RESEARCH DESIGN AND METHODS Subjects from the TrialNet Pathway to Prevention Study (N = 48,026) were screened from 2004 to 2015 for islet autoantibodies (GAD antibody [GADA], insulinoma-associated antigen 2 [IA-2A] , and autoantibodies against insulin [IAA]). Of these subjects, 17,226 (157 identical twins, 283 nonidentical twins, and 16,786 full siblings) were followed for autoantibody positivity or type 1 diabetes for a median of 2.1 years. RESULTS At screening, identical twins were more likely to have positive GADA, IA-2A, and IAA than nonidentical twins or full siblings (all P & lt; 0.0001). Younger age, male sex, and genetic factors were significant factors for expression of IA-2A, IAA, one or more positive autoantibodies, and two or more positive autoantibodies (all P ≤ 0.03). Initially autoantibody-positive identical twins had a 69% risk of diabetes by 3 years compared with 1.5% for initially autoantibody-negative identical twins. In nonidentical twins, type 1 diabetes risk by 3 years was 72% for initially multiple autoantibody–positive, 13% for single autoantibody–positive, and 0% for initially autoantibody-negative nonidentical twins. Full siblings had a 3-year type 1 diabetes risk of 47% for multiple autoantibody–positive, 12% for single autoantibody–positive, and 0.5% for initially autoantibody-negative subjects. CONCLUSIONS Risk of type 1 diabetes at 3 years is high for initially multiple and single autoantibody–positive identical twins and multiple autoantibody–positive nonidentical twins. Genetic predisposition, age, and male sex are significant risk factors for development of positive autoantibodies in twins.
    Type of Medium: Online Resource
    ISSN: 0149-5992 , 1935-5548
    URL: Article
    DOI: 10.2337/dc18-0288
    Language: English
    Publisher: American Diabetes Association
    Publication Date: 2019
    detail.hit.zdb_id: 1490520-6
    detail.hit.zdb_id: 441231-X
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  • 2
    Online Resource
    Online Resource
    Grand Rounds
    Oxford University Press (OUP) ; 2009
    In:  Archives of Clinical Neuropsychology Vol. 24, No. 5 ( 2009-08-01), p. 431-540
    Details
    In: Archives of Clinical Neuropsychology, Oxford University Press (OUP), Vol. 24, No. 5 ( 2009-08-01), p. 431-540
    Type of Medium: Online Resource
    ISSN: 0887-6177 , 1873-5843
    URL: Article
    DOI: 10.1093/arclin/acp045
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2009
    detail.hit.zdb_id: 632972-X
    detail.hit.zdb_id: 2003528-7
    SSG: 5,2
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    Online Resource
  • 3
    Online Resource
    Online Resource
    Developing the Human Factors/Ergonomics Discipline to Support Diversity, Equity and Inclusion
    SAGE Publications ; 2022
    In:  Proceedings of the Human Factors and Ergonomics Society Annual Meeting Vol. 66, No. 1 ( 2022-09), p. 139-141
    Details
    In: Proceedings of the Human Factors and Ergonomics Society Annual Meeting, SAGE Publications, Vol. 66, No. 1 ( 2022-09), p. 139-141
    Abstract: Human Factors and Ergonomics (HFE) is recognized as crucial to addressing societal challenges that are systemic in nature, including issues of diversity, equity and inclusion. The Chartered Institute of Ergonomics and Human Factors (CIEHF) recently issued a guidance outlining how HFE can help address DEI issues, in line with the Annual Meeting activities organized by the Human Factors and Ergonomics Society (HFES) Diversity and Inclusion Committee since 2016. This panel brings together the author of the CIEHF report, a former President of CIEHF and two HFES members to discuss DEI issues in HFE science HFE. The goal of this session is to identify needs and opportunities within HF/E to directly support DEI initiatives and approaches, both within and external to our disciplinary societies. This is an interactive session between the attendees guided by the panelists.
    Type of Medium: Online Resource
    ISSN: 2169-5067 , 1071-1813
    URL: Article
    DOI: 10.1177/1071181322661020
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 1194841-3
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  • 4
    Online Resource
    Online Resource
    Designing mobile health to align with the social determinants of health
    Frontiers Media SA ; 2023
    In:  Frontiers in Digital Health Vol. 5 ( 2023-5-18)
    Details
    In: Frontiers in Digital Health, Frontiers Media SA, Vol. 5 ( 2023-5-18)
    Abstract: The maternal health crisis in the United States is becoming increasingly worse, with disparities continuing to escalate among marginalized populations. mHealth can contribute to addressing the Social Determinants of Health (SDOH) that produce inequities in maternal morbidity and mortality. Reducing inequities through mHealth can be achieved by designing these technologies to align with SDOH. As mHealth developed to support maternal health has primarily supported the extension of clinical care, there is an opportunity to integrate frameworks and methods from human factors/ergonomics and public health to produce thorough comprehension of SDOH through intentional partnerships with marginalized populations. Potential for this opportunity is presented through a case study derived from a community-based participatory research process focused on transportation access to maternal health services. Through multi-faceted, interdisciplinary, and community-based approaches to designing mHealth that attends to the systemic factors that generate and escalate inequities, improvements in the maternal health crisis could be realized.
    Type of Medium: Online Resource
    ISSN: 2673-253X
    URL: Article
    DOI: 10.3389/fdgth.2023.1193920
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2023
    detail.hit.zdb_id: 3017798-4
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  • 5
    Online Resource
    Online Resource
    Meeting the challenge: Health information technology’s essential role in achieving precision medicine
    Oxford University Press (OUP) ; 2021
    In:  Journal of the American Medical Informatics Association Vol. 28, No. 6 ( 2021-06-12), p. 1345-1352
    Details
    In: Journal of the American Medical Informatics Association, Oxford University Press (OUP), Vol. 28, No. 6 ( 2021-06-12), p. 1345-1352
    Abstract: Precision medicine can revolutionize health care by tailoring treatments to individual patient needs. Advancing precision medicine requires evidence development through research that combines needed data, including clinical data, at an unprecedented scale. Widespread adoption of health information technology (IT) has made digital clinical data broadly available. These data and information systems must evolve to support precision medicine research and delivery. Specifically, relevant health IT data, infrastructure, clinical integration, and policy needs must be addressed. This article outlines those needs and describes work the Office of the National Coordinator for Health Information Technology is leading to improve health IT through pilot projects and standards and policy development. The Office of the National Coordinator for Health Information Technology will build on these efforts and continue to coordinate with other key stakeholders to achieve the vision of precision medicine. Advancement of precision medicine will require ongoing, collaborative health IT policy and technical initiatives that advance discovery and transform healthcare delivery.
    Type of Medium: Online Resource
    ISSN: 1527-974X
    URL: Article
    DOI: 10.1093/jamia/ocab032
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2021
    detail.hit.zdb_id: 2018371-9
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  • 6
    Online Resource
    Online Resource
    Informatics-enabled citizen science to advance health equity
    Oxford University Press (OUP) ; 2021
    In:  Journal of the American Medical Informatics Association Vol. 28, No. 9 ( 2021-08-13), p. 2009-2012
    Details
    In: Journal of the American Medical Informatics Association, Oxford University Press (OUP), Vol. 28, No. 9 ( 2021-08-13), p. 2009-2012
    Abstract: The COVID-19 pandemic has once again highlighted the ubiquity and persistence of health inequities along with our inability to respond to them in a timely and effective manner. There is an opportunity to address the limitations of our current approaches through new models of informatics-enabled research and clinical practice that shift the norm from small- to large-scale patient engagement. We propose augmenting our approach to address health inequities through informatics-enabled citizen science, challenging the types of questions being asked, prioritized, and acted upon. We envision this democratization of informatics that builds upon the inclusive tradition of community-based participatory research (CBPR) as a logical and transformative step toward improving individual, community, and population health in a way that deeply reflects the needs of historically marginalized populations.
    Type of Medium: Online Resource
    ISSN: 1527-974X
    URL: Article
    DOI: 10.1093/jamia/ocab088
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2021
    detail.hit.zdb_id: 2018371-9
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  • 7
    Online Resource
    Online Resource
    Expanding human factors/ergonomics to address social determinants of health: A patient ergonomics approach to birth justice
    Elsevier BV ; 2024
    In:  International Journal of Industrial Ergonomics Vol. 99 ( 2024-01), p. 103528-
    Details
    In: International Journal of Industrial Ergonomics, Elsevier BV, Vol. 99 ( 2024-01), p. 103528-
    Type of Medium: Online Resource
    ISSN: 0169-8141
    URL: Article
    DOI: 10.1016/j.ergon.2023.103528
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2024
    detail.hit.zdb_id: 2009098-5
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  • 8
    Online Resource
    Online Resource
    Designing Consumer Health Information Technology to Support Biform and Articulation Work: A Qualitative Study of Diet and Nutrition Management as Patient Work
    JMIR Publications Inc. ; 2021
    In:  JMIR Human Factors Vol. 8, No. 3 ( 2021-8-10), p. e27452-
    Details
    In: JMIR Human Factors, JMIR Publications Inc., Vol. 8, No. 3 ( 2021-8-10), p. e27452-
    Abstract: Diet and nutrition management is an integral component of Crohn disease (CD) management. This type of management is highly variable and individualized and, thus, requires personalized approaches. Consumer health information technology (CHIT) designed to support CD management has typically supported this task as everyday life work and, not necessarily, as illness work. Moreover, CHIT has rarely supported the ways in which diet and nutrition management requires coordination between multiple forms of patient work. Objective The purpose of this study was to investigate diet and nutrition management as biform work, identify components of articulation work, and provide guidance on how to design CHIT to support this work. Methods We performed a qualitative study in which we recruited participants from CD-related Facebook pages and groups. Results Semistructured interviews with 21 individuals showed that diet and nutrition management strategies were highly individualized and variable. Four themes emerged from the data, emphasizing the interactions of diet and nutrition with physical, emotional, information, and technology-enabled management. Conclusions This study shows that the extent to which diet and nutrition management is biform work fluctuates over time and that articulation work can be continuous and unplanned. The design guidance specifies the need for patient-facing technologies to support interactions among diet and nutrition and other management activities such as medication intake, stress reduction, and information seeking, as well as to respond to the ways in which diet and nutrition management needs change over time.
    Type of Medium: Online Resource
    ISSN: 2292-9495
    URL: Article
    DOI: 10.2196/27452
    Language: English
    Publisher: JMIR Publications Inc.
    Publication Date: 2021
    detail.hit.zdb_id: 2874187-0
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  • 9
    Online Resource
    Online Resource
    Consumer Health Informatics for Racial and Ethnic Minoritized Communities: Minor Progress, Major Opportunities
    Georg Thieme Verlag KG ; 2022
    In:  Yearbook of Medical Informatics Vol. 31, No. 01 ( 2022-08), p. 167-172
    Details
    In: Yearbook of Medical Informatics, Georg Thieme Verlag KG, Vol. 31, No. 01 ( 2022-08), p. 167-172
    Abstract: Objective: By reducing barriers to accessing health services and by supporting health management, consumer health informatics has the potential to reduce health disparities. Yet, technologies are still being designed without considerations for racial and ethnic minoritized populations. This paper reviews consumer health informatics research within this population to assess for whom and how such technologies are being designed. Methods: We searched four databases from January 2020- December 2021 for literature focused on consumer health informatics and racial and ethnic minoritized populations. We extracted information about the study population, geographic location, stage of the design lifecycle, culturally tailored approaches, community engagement strategies, and considerations for the social determinants of health. Results: Twenty articles were included in the review. Most of the included literature were original research articles that tested health management interventions focused on one racial or ethnic minoritized population primarily within a confined geographic area within the United States. Seven studies described the extent to which an intervention was culturally tailored, including modifying the content, interface, functionality, and platform. Community engagement strategies varied, but few articles employed robust approaches. Lastly, seven studies detailed considerations for the social determinants of health, including providing hardware to access interventions and incorporating information about community-based resources within an intervention. Conclusions: There has been moderate progress in consumer health informatics focused on racial and ethnic minoritized populations and many opportunities remain for these technologies to be used as an approach to address health disparities. Future research should utilize community engagement strategies to design interventions that are attune to multiple racial and ethnic minoritized populations across geographic regions in addition to numerous intersectional identities and multiple co-morbidities.
    Type of Medium: Online Resource
    ISSN: 0943-4747 , 2364-0502
    URL: Article
    DOI: 10.1055/s-0042-1742520
    Language: English
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2022
    detail.hit.zdb_id: 1136921-8
    detail.hit.zdb_id: 2251229-9
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  • 10
    Online Resource
    Online Resource
    The lived experience during the peri-diagnostic period of breast cancer: A scoping review
    Elsevier BV ; 2022
    In:  Patient Education and Counseling Vol. 105, No. 3 ( 2022-03), p. 547-585
    Details
    In: Patient Education and Counseling, Elsevier BV, Vol. 105, No. 3 ( 2022-03), p. 547-585
    Type of Medium: Online Resource
    ISSN: 0738-3991
    URL: Article
    DOI: 10.1016/j.pec.2021.06.017
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2022
    detail.hit.zdb_id: 605590-4
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