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  • 1
    In: Movement Disorders, Wiley, Vol. 19, No. 1 ( 2004-01), p. 29-35
    Abstract: Twenty‐nine elderly patients who failed treatment with clozapine, risperidone, or olanzapine entered this 24‐week, single‐center, open‐label trial to assess the efficacy of quetiapine (12.5–400 mg/day) for psychosis in patients with Parkinson's disease (PD). Psychiatric, motor, and cognitive assessments were administered at baseline and at periodic intervals for 24 weeks. These included the Brief Psychiatric Rating Scale (BPRS), Neuropsychiatric Inventory (NPI), Unified Parkinson's Disease Rating Scale (UPDRS) and tests of intellectual functioning, attention, and memory. Repeated measures statistical analysis was used to assess change from baseline. The results revealed significant improvements in the 24‐week BPRS total score and NPI psychosis subscale scores, with no decline in UPDRS total or motor subscale scores. There was also significant improvement in recall scores on cognitive measures. These results indicate that quetiapine may treat psychotic symptoms and improve cognition without worsening motor function in patients with PD, suggesting that quetiapine is an effective and well‐tolerated antipsychotic in this population. © 2003 Movement Disorder Society
    Type of Medium: Online Resource
    ISSN: 0885-3185 , 1531-8257
    URL: Issue
    RVK:
    Language: English
    Publisher: Wiley
    Publication Date: 2004
    detail.hit.zdb_id: 2041249-6
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  • 2
    In: Bulletin of the American Meteorological Society, American Meteorological Society, Vol. 103, No. 2 ( 2022-02), p. E485-E510
    Abstract: Up to 1,000 drowning deaths occur every year on Lake Victoria in East Africa. Nocturnal thunderstorms are one of the main culprits for the high winds and waves that cause fishing boats to capsize. The High Impact Weather Lake System (HIGHWAY) project was established to develop an Early Warning System for Lake Victoria. Prior to HIGHWAY, weather forecasts for the lake were overly general and not trusted. Under the HIGHWAY project, forecasters from weather service offices in East Africa worked with leaders of fishing communities and Beach Management Units to develop marine forecasts and hazardous-weather warnings that were meaningful to fishermen and other stakeholders. Forecasters used high-resolution satellite, radar, and lightning observations collected during a HIGHWAY field campaign, along with guidance from numerical weather prediction models and a 4.4-km resolution Tropical Africa model, to produce specific forecasts and warnings for 10 zones over the lake. Forecasts were communicated to thousands of people by radio broadcasters, local intermediaries, and via smartphones using the WhatsApp application. Fishermen, ferry-boat operators, and lakeside communities used the new marine forecasts to plan their daytime and nighttime activities on the lake. A socioeconomic benefits study conducted by HIGHWAY found that ∼75% of the people are now using the forecasts to decide if and when to travel on the lake. Significantly, a 30% reduction in drowning fatalities on the lake is likely to have occurred, which, when combined with the reduction in other weather-related losses, generates estimated socioeconomic benefits of $44 million per year due to the HIGHWAY project activities; the new marine forecasts and warnings are helping to save lives and property.
    Type of Medium: Online Resource
    ISSN: 0003-0007 , 1520-0477
    Language: Unknown
    Publisher: American Meteorological Society
    Publication Date: 2022
    detail.hit.zdb_id: 2029396-3
    detail.hit.zdb_id: 419957-1
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  • 3
    Online Resource
    Online Resource
    American Meteorological Society ; 2022
    In:  Monthly Weather Review Vol. 150, No. 10 ( 2022-10), p. 2485-2502
    In: Monthly Weather Review, American Meteorological Society, Vol. 150, No. 10 ( 2022-10), p. 2485-2502
    Abstract: The enhanced observation period during the HIGHWAY field campaign in East Africa provided the opportunity to obtain continuous ground-based radar observations over the Lake Victoria basin. This provided insight into thunderstorm initiation processes and thunderstorm evolution. This insight is significant for it can lead to nowcasting thunderstorms over Lake Victoria, which is particularly important because of the 〉 200 000 fishers using the lake daily and the extremely high number of drownings resulting from capsized boats caused by large waves and high winds from thunderstorms. Radar data from the south shoreline of Lake Victoria made it possible to observe thunderstorm activity over the entire lake. Unexpectedly the radar returns from high concentration of insects over the lake made it possible for the radar to observe boundary layer convergence lines. With this information a radar-trained forecaster could provide nowcasts of severe storm locations and by using extrapolation techniques provide nowcasts of their future location. In addition, rules for forecasting the timing and extent of nighttime thunderstorm activity over the lake based on radar monitoring of earlier activity along the northeast land/lake region are provided. While there are many obstacles to overcome, it is hoped that in the near future this possible life-saving information can be provided to Lake Victoria boaters. Significance Statement Radar data from the south shore of Lake Victoria has enabled new understanding of thunderstorm initiation and evolution over the lake. This understanding provides the potential to nowcast thunderstorms over Lake Victoria. This is particularly important because of the extremely high number of drownings that occur over the lake that result from capsized boats caused by large waves and high winds from thunderstorms. Radar-based rules are provided for forecasting and nowcasting the timing and severity of Lake Victoria thunderstorms.
    Type of Medium: Online Resource
    ISSN: 0027-0644 , 1520-0493
    RVK:
    Language: Unknown
    Publisher: American Meteorological Society
    Publication Date: 2022
    detail.hit.zdb_id: 2033056-X
    detail.hit.zdb_id: 202616-8
    SSG: 14
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  • 4
    Online Resource
    Online Resource
    American Meteorological Society ; 2010
    In:  Weather and Forecasting Vol. 25, No. 6 ( 2010-12-01), p. 1691-1714
    In: Weather and Forecasting, American Meteorological Society, Vol. 25, No. 6 ( 2010-12-01), p. 1691-1714
    Abstract: The Beijing 2008 Forecast Demonstration Project (B08FDP) included a variety of nowcasting systems from China, Australia, Canada, and the United States. A goal of the B08FDP was to demonstrate state-of-the-art nowcasting systems within a mutual operational setting. The nowcasting systems were a mix of radar echo extrapolation methods, numerical models, techniques that blended numerical model and extrapolation methods, and systems incorporating forecaster input. This paper focuses on the skill of the nowcasting systems to forecast convective storms that threatened or affected the Summer Olympic Games held in Beijing, China. The topography surrounding Beijing provided unique challenges in that it often enhanced the degree and extent of storm initiation, growth, and dissipation, which took place over short time and space scales. The skill levels of the numerical techniques were inconsistent from hour to hour and day to day and it was speculated that without assimilation of real-time radar reflectivity and Doppler velocity fields to support model initialization, particularly for weakly forced convective events, it would be very difficult for models to provide accurate forecasts on the nowcasting time and space scales. Automated blending techniques tended to be no more skillful than extrapolation since they depended heavily on the models to provide storm initiation, growth, and dissipation. However, even with the cited limitations among individual nowcasting systems, the Chinese Olympic forecasters considered the B08FDP human consensus forecasts to be useful. Key to the success of the human forecasts was the development of nowcasting rules predicated on the character of Beijing convective weather realized over the previous two summers. Based on the B08FDP experience, the status of nowcasting convective storms and future directions are presented.
    Type of Medium: Online Resource
    ISSN: 1520-0434 , 0882-8156
    Language: English
    Publisher: American Meteorological Society
    Publication Date: 2010
    detail.hit.zdb_id: 2025194-4
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  • 5
    Online Resource
    Online Resource
    American Meteorological Society ; 2012
    In:  Weather and Forecasting Vol. 27, No. 5 ( 2012-10-01), p. 1061-1089
    In: Weather and Forecasting, American Meteorological Society, Vol. 27, No. 5 ( 2012-10-01), p. 1061-1089
    Abstract: A forecaster-interactive capability was added to an automated convective storm nowcasting system [Auto-Nowcaster (ANC)] to allow forecasters to enhance the performance of 1-h nowcasts of convective storm initiation and evolution produced every 6 min. This Forecaster-Over-The-Loop (FOTL-ANC) system was tested at the National Weather Service Fort Worth–Dallas, Texas, Weather Forecast Office during daily operations from 2005 to 2010. The forecaster’s role was to enter the locations of surface convergence boundaries into the ANC prior to dissemination of nowcasts to the Center Weather Service Unit. Verification of the FOTL-ANC versus ANC (no human) nowcasts was conducted on the convective scale. Categorical verification scores were computed for 30 subdomains within the forecast domain. Special focus was placed on subdomains that included convergence boundaries for evaluation of forecaster involvement and impact on the FOTL-ANC nowcasts. The probability of detection of convective storms increased by 20%–60% with little to no change observed in the false-alarm ratios. Bias values increased from 0.8–1.0 to 1.0–3.0 with human involvement. The accuracy of storm nowcasts notably improved with forecaster involvement; critical success index (CSI) values increased from 0.15–0.25 (ANC) to 0.2–0.4 (FOTL-ANC). Over short time periods, CSI values as large as 0.6 were also observed. This study demonstrated definitively that forecaster involvement led to positive improvement in the nowcasts in most cases while causing no degradation in other cases; a few exceptions are noted. Results show that forecasters can play an important role in the production of rapidly updated, convective storm nowcasts for end users.
    Type of Medium: Online Resource
    ISSN: 0882-8156 , 1520-0434
    Language: English
    Publisher: American Meteorological Society
    Publication Date: 2012
    detail.hit.zdb_id: 2025194-4
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  • 6
    In: American Heart Journal, Elsevier BV, Vol. 127, No. 4 ( 1994-04), p. 738-743
    Type of Medium: Online Resource
    ISSN: 0002-8703
    RVK:
    Language: English
    Publisher: Elsevier BV
    Publication Date: 1994
    detail.hit.zdb_id: 2003210-9
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  • 7
    In: Atmosphere, MDPI AG, Vol. 10, No. 11 ( 2019-11-13), p. 706-
    Abstract: Lake Victoria in East Africa supports the livelihood of thousands of fishermen and it is estimated that 3000–5000 human deaths occur per year over the lake. It is hypothesized that most of these fatalities are due to localized, severe winds produced by intense thunderstorms over the lake during the rainy season and larger scale, intense winds over the lake during the dry season. The intense winds produce a rough state of the lake (big wave heights) that cause fishing boats to capsize. In this region, weather radars have never been a primary tool for monitoring and nowcasting high impact weather. The Tanzania Meteorological Agency operates an S-band polarimetric radar in Mwanza, Tanzania, along the south shore of Lake Victoria. This radar collects high temporal and spatial resolution data that is now being used to detect and monitor the formation of deep convection over the lake and improve scientific understanding of storm dynamics and intensification. Nocturnal thunderstorms and convection initiation over the lake are well observed by the Mwanza radar and are strongly forced by lake and land breezes and gust fronts. Unexpected is the detection of clear air echo to ranges ≥100 km over the lake that makes it possible to observe low-level winds, gust fronts, and other convergence lines near the surface of the lake. The frequent observation of extensive clear air and low-level convergence lines opens up the opportunity to nowcast strong winds, convection initiation, and subsequent thunderstorm development and incorporate this information into a regional early warning system proposed for Lake Victoria Basin (LVB). Two weather events are presented illustrating distinctly different nocturnal convection initiation over the lake that evolve into intense morning thunderstorms. The evolution of these severe weather events was possible because of the Mwanza radar observations; satellite imagery alone was insufficient to provide prediction of storm initiation, growth, movement, and decay.
    Type of Medium: Online Resource
    ISSN: 2073-4433
    Language: English
    Publisher: MDPI AG
    Publication Date: 2019
    detail.hit.zdb_id: 2605928-9
    SSG: 23
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  • 8
    Online Resource
    Online Resource
    American Meteorological Society ; 2003
    In:  Weather and Forecasting Vol. 18, No. 4 ( 2003-08), p. 562-584
    In: Weather and Forecasting, American Meteorological Society, Vol. 18, No. 4 ( 2003-08), p. 562-584
    Type of Medium: Online Resource
    ISSN: 0882-8156 , 1520-0434
    Language: English
    Publisher: American Meteorological Society
    Publication Date: 2003
    detail.hit.zdb_id: 2025194-4
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  • 9
    Online Resource
    Online Resource
    American Meteorological Society ; 2012
    In:  Weather and Forecasting Vol. 27, No. 5 ( 2012-10-01), p. 1178-1197
    In: Weather and Forecasting, American Meteorological Society, Vol. 27, No. 5 ( 2012-10-01), p. 1178-1197
    Abstract: In this study, a fuzzy logic algorithm is developed to provide objective guidance for the prediction of afternoon thunderstorms in northern Taiwan using preconvective predictors during the warm season (May–October) from 2005 to 2008. The predictors are derived from surface stations and sounding measurements. The study is limited to 277 days when synoptic forcing was weak and thermal instability produced by the solar heating is primarily responsible for thunderstorm initiation. The fuzzy algorithm contains 29 predictors and associated weights. The weights are based on the maximum of the critical success index (CSI) to forecast afternoon thunderstorms. The most important predictors illustrate that under relatively warm and moist synoptic conditions, sea-breeze transport of moisture into the Taipei Basin along with weak winds inland provide favorable conditions for the occurrence of afternoon convective storms. In addition, persistence of yesterday’s convective storm activity contributed to improving today’s forecast. Skill score comparison between the fuzzy algorithm and forecasters from the Taiwan Central Weather Bureau showed that for forecasting afternoon thunderstorms, the fuzzy logic algorithm outperformed the operational forecasters. This was the case for both the calibration and independent datasets. There was a tendency for the forecasters to overforecast the number of afternoon thunderstorm days. The fuzzy logic algorithm is able to integrate the preconvective predictors and provide probability guidance for the prediction of afternoon thunderstorms under weak synoptic-scale conditions, and could be implemented in real-time operations as a forecaster aid.
    Type of Medium: Online Resource
    ISSN: 0882-8156 , 1520-0434
    Language: English
    Publisher: American Meteorological Society
    Publication Date: 2012
    detail.hit.zdb_id: 2025194-4
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  • 10
    Online Resource
    Online Resource
    American Meteorological Society ; 1989
    In:  Journal of Applied Meteorology Vol. 28, No. 4 ( 1989-04), p. 285-303
    In: Journal of Applied Meteorology, American Meteorological Society, Vol. 28, No. 4 ( 1989-04), p. 285-303
    Type of Medium: Online Resource
    ISSN: 0894-8763 , 1520-0450
    Language: English
    Publisher: American Meteorological Society
    Publication Date: 1989
    detail.hit.zdb_id: 242493-9
    detail.hit.zdb_id: 2027356-3
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