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  • 1
    Online Resource
    Online Resource
    Global multi-stakeholder endorsement of the MAFLD definition
    Elsevier BV ; 2022
    In:  The Lancet Gastroenterology & Hepatology Vol. 7, No. 5 ( 2022-05), p. 388-390
    Details
    In: The Lancet Gastroenterology & Hepatology, Elsevier BV, Vol. 7, No. 5 ( 2022-05), p. 388-390
    Type of Medium: Online Resource
    ISSN: 2468-1253
    URL: Article
    DOI: 10.1016/S2468-1253(22)00062-0
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2022
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  • 2
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    EFFECTS OF THERMAL MANIPULATION OF JAPANESE QUAIL EMBRYO ON POST-HATCH CARCASS TRAITS, WEIGHT OF INTERNAL ORGANS, AND BREAST MEAT QUALITY
    University of Ljubljana ; 2023
    In:  SLOVENIAN VETERINARY RESEARCH Vol. 60, No. 2 ( 2023-04-03)
    Details
    In: SLOVENIAN VETERINARY RESEARCH, University of Ljubljana, Vol. 60, No. 2 ( 2023-04-03)
    Abstract: Embryonic thermal manipulation was known as an effective protocol for improving post-hatch growth performance and thermotolerance acquisition among avian species. Previously, we evaluated the impact of embryonic thermal manipulation of Japanese quail on embryonic development, hatchability, and post-hatch performance. We conducted the current study to furtherly elucidate the effects of thermal manipulations of Japanese quail embryos on internal organ weights, carcass traits, and meat quality parameters at post-hatch day 35. Quail eggs of control group were incubated at 37.7 °C and relative humidity (RH) 55%. Three thermally manipulated groups of quail eggs were incubated intermittently at 41°C and 65% RH intermittently (3 hours/day): the early embryonic group (TM1) was thermally challenged at embryonic day (ED6) to ED8, the late embryonic group (TM2) was thermally challenged at ED12-14, and early/late embryonic group (TM3) was thermally challenged in both time windows. Quail meat quality parameters, carcass traits, and internal organ weights were evaluated at post-hatch day 35. The results revealed that early embryonic thermal manipulation (TM1 group) is an effective protocol for decreasing fat pad accumulation. The pH value of breast meat in all TM treatments revealed significant (P 〈 0.05) decreases by 5% in comparison with that of control without any negative effects on breast meat composition or sensory criteria. Early embryonic thermal manipulation would be recommended as an enhanced protocol that can be used to reach the favored lucrative effects of the thermal treatment in meat-type quail. UČINKI TOPLOTNE MANIPULACIJE ZARODKOV JAPONSKIH PREPELIC NA LASTNOSTI TRUPA PO IZVALITVI, TEŽO NOTRANJIH ORGANOV IN KAKOVOST PRSNEGA MESA Izvleček: Toplotna manipulacija zarodka različnih vrst ptic je znana kot učinkovit protokol za izboljšanje rasti po izvalitvi in pridobivanje odpornosti na povišano temperaturo. Predhodno smo ocenili vpliv embrionalne toplotne manipulacije zarodkov japonskih prepelic na embrionalni razvoj, valilnost in uspešnost po izvalitvi. V tej študiji smo natančneje pojasnili učinke toplotne manipulacije zarodkov japonskih prepelic na težo notranjih organov, lastnosti trupa in parametre kakovosti mesa na 35. dan po izvalitvi. Jajca prepelic kontrolne skupine so bila inkubirana pri 37,7 °C in 55-odstotni relativni vlažnosti. Tri preiskovane skupine prepeličjih jajc so bile občasno izpostavljene temperaturi 41 °C in relativni vlagi 65 % (3 ure/dan): zgodnja embrionalna skupina (TM1) je bila izpostavljena toploti 6.– 8. embrionalni dan (ED), pozna embrionalna skupina (TM2) 12.–14. ED, zgodnja/pozna embrionalna skupina (TM3) pa v obeh časovnih intervalih. Parametre kakovosti mesa prepelic, lastnosti trupa in težo notranjih organov smo ocenili na 35. dan po izvalitvi. Rezultati so pokazali, da je toplotna manipulacija v zgodnjem embrionalnem obdobju (skupina TM1) učinkovit protokol za zmanjšanje kopičenja maščobnih blazinic. Vrednost pH prsnega mesa pri vseh toplotno manipuliranih skupinah se je znatno (P 〈 0,05) znižala za 5 % v primerjavi s kontrolno skupino, brez negativnih učinkov na sestavo prsnega mesa ali senzorične kriterije. Zgodnjo embrionalno toplotno manipulacijo bi bilo priporočljivo uporabiti kot izboljšan protokol, s katerim bi bilo mogoče doseči prednostne donosne učinke pri mesnih prepelicah. Ključne besede: Coturnix japonica; mesna prepelica; lastnosti prsnega mesa; toplotna biologija  
    Type of Medium: Online Resource
    ISSN: 1580-4003
    URL: Article
    DOI: 10.26873/SVR-1525-2023
    Language: Unknown
    Publisher: University of Ljubljana
    Publication Date: 2023
    detail.hit.zdb_id: 2241136-7
    SSG: 22
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  • 3
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    Cisplatin-induced azoospermia and testicular damage ameliorated by adipose-derived mesenchymal stem cells
    Springer Science and Business Media LLC ; 2023
    In:  Biological Research Vol. 56, No. 1 ( 2023-01-19)
    Details
    In: Biological Research, Springer Science and Business Media LLC, Vol. 56, No. 1 ( 2023-01-19)
    Abstract: The testes are highly susceptible to the adverse effects of chemotherapy and radiation at all stages of life. Exposure to these threats mainly occurs during cancer treatment and as an occupational hazard in radiation centers. The present study investigated the regenerative ability of adipose-derived mesenchymal stem cells (ADMSCs) against the adverse effects of cisplatin on the structure and function of the testes. Methods New Zealand white rabbits (N = 15) were divided into three groups of five: a negative control group (no treatment), a cisplatin group (single dose of cisplatin into each testis followed three days later by a PBS injection), and a cisplatin + ADMSCs group (cisplatin injection followed three days later by an ADMSC injection). On day 45 post-treatment, serum testosterone levels were evaluated, and the testes and epididymis were collected for histology, oxidative stress examination, and epididymal sperm analysis. Results Cisplatin caused damage to the testicular tissue and decreased serum testosterone levels, epididymal sperm counts, and oxidants. An antioxidant imbalance was detected due to increasing malondialdehyde (MDA) and reduced glutathione (GSH) levels in testicular tissue. The ADMSC-treated group displayed a moderate epididymal sperm count, adequate antioxidant protection, suitable hormone levels, and enhanced testicular tissue morphology. Conclusions ADMSCs treatment repaired damaged testicular tissue, enhanced biochemical parameters, and modified pathological changes caused by cisplatin.
    Type of Medium: Online Resource
    ISSN: 0717-6287
    URL: Article
    DOI: 10.1186/s40659-022-00410-5
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2048380-6
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  • 4
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    Stem Cell Treatment Trials for Regeneration of Testicular Tissue in Laboratory Animals
    Springer Science and Business Media LLC ; 2023
    In:  Reproductive Sciences Vol. 30, No. 6 ( 2023-06), p. 1770-1781
    Details
    In: Reproductive Sciences, Springer Science and Business Media LLC, Vol. 30, No. 6 ( 2023-06), p. 1770-1781
    Abstract: Infertility is a serious medical, economic, and psychological problem in the society. Male factor infertility, due to defective spermatogenesis as a result of a failure in germ cell proliferation and differentiation, appears to be the cause of 25–50% of infertility cases. According to several surveys, testicular degeneration can be caused by a variety of physical, chemical, and microbial causes. A stem cell is a non-specialized cell which is characterized by self-renewal by mitotic cell division and able to differentiate to specialized cells for the various tissues of the body. The data were obtained and analyzed from different databases (PubMed, Google Scholar, Egyptian Knowledge Bank, Elsevier, Medline, Embase, ProQuest, and BMC). This review discusses the causes, symptoms, and grades of testicular degeneration and the use of different types of stem cells in regeneration. And its conclusion based on previous researches and trials, MSCs are considered effective therapy for testicular degeneration.
    Type of Medium: Online Resource
    ISSN: 1933-7191 , 1933-7205
    URL: Article
    DOI: 10.1007/s43032-022-01152-1
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2266096-3
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  • 5
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    Knowledge, attitudes, practices and perceived barriers towards research in undergraduate medical students of six Arab countries
    Springer Science and Business Media LLC ; 2022
    In:  BMC Medical Education Vol. 22, No. 1 ( 2022-01-18)
    Details
    In: BMC Medical Education, Springer Science and Business Media LLC, Vol. 22, No. 1 ( 2022-01-18)
    Abstract: The involvement of the undergraduates in the research field requires a better view of their potential and the anticipated barriers facing them. This study aims to assess the undergraduates' knowledge, attitudes, practices and perceived barriers towards research in six Arab countries. Methods A cross sectional study included medical students from six Arab countries, where a self-administered five-section questionnaire was used to assess the students' demographics, knowledge, attitudes, practices and perceived barriers. The questionnaire was distributed in the online educational platforms of the participating medical schools in the six included countries. Results The total sample of recruited students was 2989, the majority of students (91.6%) showed poor level of knowledge regarding research. Generally high levels of positive attitudes towards research, research relevance and usefulness were found, with moderate levels of perception of research anxiety and difficulty. 33.7% ( n  = 1006) participated in an actual research project before with a mean of .5 publications per student. Cross-sectional studies were the most common type of studies conducted by students (38.6%), followed by case reports (23.9%). Lack of access to lab equipment for lab research (68.1%), the priority of education over research (66.8%), and lack of time because of educational tasks (66.1%) were generally the top perceived barriers towards research practice. Conclusion In the current study, the participants showed a poor knowledge level with associated positive attitudes towards research. One third of the students participated in research projects that mostly were cross-sectional studies and case reports. Educational tasks and lack of support were the most prevalent barriers. The students' positive attitudes towards research need to be translated into better knowledge and appropriate practice, which can be done by development of better training systems and more structured mentoring.
    Type of Medium: Online Resource
    ISSN: 1472-6920
    URL: Article
    DOI: 10.1186/s12909-022-03121-3
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2044473-4
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  • 6
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    Morphological and Laboratory improvement of Cisplatin - induced azoospermia using Adipose derived mesenchymal stem cells in a Rabbit model
    Egypts Presidential Specialized Council for Education and Scientific Research ; 2022
    In:  Veterinary Medical Journal (Giza) Vol. 0, No. 0 ( 2022-11-06), p. 80-94
    Details
    In: Veterinary Medical Journal (Giza), Egypts Presidential Specialized Council for Education and Scientific Research, Vol. 0, No. 0 ( 2022-11-06), p. 80-94
    Type of Medium: Online Resource
    ISSN: 2537-1045
    URL: Article
    DOI: 10.21608/vmjg.2022.170699.1016
    Language: English
    Publisher: Egypts Presidential Specialized Council for Education and Scientific Research
    Publication Date: 2022
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  • 7
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    Role of Ozone in Surgical Complication of Diabetic Patients
    Egypts Presidential Specialized Council for Education and Scientific Research ; 2018
    In:  SVU-International Journal of Medical Sciences Vol. 1, No. 1 ( 2018-07-01), p. 14-16
    Details
    In: SVU-International Journal of Medical Sciences, Egypts Presidential Specialized Council for Education and Scientific Research, Vol. 1, No. 1 ( 2018-07-01), p. 14-16
    Type of Medium: Online Resource
    ISSN: 2636-3402
    URL: Article
    DOI: 10.21608/svuijm.2018.120526
    Language: English
    Publisher: Egypts Presidential Specialized Council for Education and Scientific Research
    Publication Date: 2018
    detail.hit.zdb_id: 3074110-5
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  • 8
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    Lung Ultrasound and Non-Invasive Ventilation Outcome in Acute Respiratory Failure
    Damietta Faculty of Medicine, Al-Azhar University, Egypt ; 2023
    In:  The Scientific Journal of Medical Scholar Vol. 2, No. 3 ( 2023-06-09), p. 71-82
    Details
    In: The Scientific Journal of Medical Scholar, Damietta Faculty of Medicine, Al-Azhar University, Egypt, Vol. 2, No. 3 ( 2023-06-09), p. 71-82
    Abstract: Objective: This study aimed to assess the diaphragmatic dysfunction in critically ill non-intubated patients admitted to respiratory critical care unit with acute respiratory failure. Methods: This was a prospective study conducted on 200 mechanically ventilated patients. The following data were collected: demographic characteristics, anthropometric measurements. Disease severity and hemodynamics. In addition, ICU length of stay, duration mechanical ventilation, outcome and duration of hospital stay.  Besides, parameters of MV like (PaO2 / FiO2 Ratio), and respiratory rate were noticed. The laboratory workup included arterial blood gases, Na+, K+, Mg++, Ca++, PH, PCO2, HCO3-. The ultrasound was performed before and after weaning and included the diaphragmatic excursion and diaphragmatic thickness traction. The patients were split into two categories regarding their reaction to weaning attempts: Category A represented successful weaning. Category B represented unsuccessful weaning followed by reintubation and mechanically ventilated. Results: The weaning success was reported for 123 patients (61.5%) and mortality reported for 28 patients (14.0%). Weaning success was associated with male gender, younger age and slightly higher BMI. Obstructive airway disease showed significant increase in success than failure (25.2% vs 11.7% respectively). Weaning failure was significantly associated increased septic shock and pneumonia. The muscle thickness in inspiration was significantly increased in success than failure (25.56 vs 24.08 respectively). DE before weaning was the most sensitive indicator at cut-off value 〉 15 followed by DE after weaning at cutoff value 〉 17; while DTF after weaning was more sensitive than DTF before weaning (93.55% and 80.65% respectively) at cutoff points 〉 20.4 and 〉 18.5, respectively. Conclusion: Assessment of DTF and DE by diaphragm ultrasound is an easy to obtain new weaning index that can be a bedside method in clinical practice with promising predictors of weaning success or failure before and after weaning.
    Type of Medium: Online Resource
    ISSN: 2833-3772
    URL: Article
    DOI: 10.55675/sjms.v2i3.51
    Language: Unknown
    Publisher: Damietta Faculty of Medicine, Al-Azhar University, Egypt
    Publication Date: 2023
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  • 9
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    Stem cell treatment trials of spinal cord injuries in animals
    Elsevier BV ; 2022
    In:  Autonomic Neuroscience Vol. 238 ( 2022-03), p. 102932-
    Details
    In: Autonomic Neuroscience, Elsevier BV, Vol. 238 ( 2022-03), p. 102932-
    Type of Medium: Online Resource
    ISSN: 1566-0702
    URL: Article
    DOI: 10.1016/j.autneu.2021.102932
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2022
    detail.hit.zdb_id: 2020182-5
    SSG: 12
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  • 10
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    Ni2+ Selective Membrane Sensors Based on Sulfamethoxazole Diazonium Resorcinol in Poly (Vinyl Chloride) (PVC) Matrix
    Springer Science and Business Media LLC ; 2013
    In:  Arabian Journal for Science and Engineering Vol. 38, No. 7 ( 2013-7), p. 1681-1689
    Details
    In: Arabian Journal for Science and Engineering, Springer Science and Business Media LLC, Vol. 38, No. 7 ( 2013-7), p. 1681-1689
    Type of Medium: Online Resource
    ISSN: 1319-8025 , 2191-4281
    URL: Article
    DOI: 10.1007/s13369-012-0383-2
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2013
    detail.hit.zdb_id: 2613699-5
    detail.hit.zdb_id: 2565741-0
    detail.hit.zdb_id: 2471504-9
    detail.hit.zdb_id: 2613713-6
    SSG: 11
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