In:
Organic & Biomolecular Chemistry, Royal Society of Chemistry (RSC), Vol. 20, No. 35 ( 2022), p. 7105-7111
Abstract:
The cooperative l -proline/Brønsted acid/base promoted reaction of 2-ethoxypyrrolidines or N -substituted 4,4-diethoxybutan-1-amines with methyl(alkyl/aryl)ketones for the synthesis of 2-(acylmethylene)pyrrolidine derivatives is reported. The key features of the developed protocol are gram-scale synthesis of the target compounds, easily available starting materials, operational simplicity and usage of non-expensive reagents.
Type of Medium:
Online Resource
ISSN:
1477-0520
,
1477-0539
Language:
English
Publisher:
Royal Society of Chemistry (RSC)
Publication Date:
2022
detail.hit.zdb_id:
2097583-1
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