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  • 1
    Online Resource
    Online Resource
    Informa UK Limited ; 1973
    In:  Scandinavian Journal of Infectious Diseases Vol. 5, No. 3 ( 1973-09), p. 187-191
    In: Scandinavian Journal of Infectious Diseases, Informa UK Limited, Vol. 5, No. 3 ( 1973-09), p. 187-191
    Type of Medium: Online Resource
    ISSN: 0036-5548 , 1651-1980
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 1973
    detail.hit.zdb_id: 2805836-7
    detail.hit.zdb_id: 1484328-6
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  • 2
    Online Resource
    Online Resource
    American Academy of Pediatrics (AAP) ; 1968
    In:  Pediatrics Vol. 41, No. 4 ( 1968-04-01), p. 733-738
    In: Pediatrics, American Academy of Pediatrics (AAP), Vol. 41, No. 4 ( 1968-04-01), p. 733-738
    Abstract: Cystic fibrosis is a generalized, familial disorder exhibiting a marked ethnic variation. This paper presents the first two cases of this disorder reported in the American Indian population. The family pedigrees of these patients are described and certain genetic aspects of this disease are discussed briefly. Possible anthropological reasons for the occurrence of this disease in this racial group are mentioned.
    Type of Medium: Online Resource
    ISSN: 0031-4005 , 1098-4275
    Language: English
    Publisher: American Academy of Pediatrics (AAP)
    Publication Date: 1968
    detail.hit.zdb_id: 1477004-0
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  • 3
    In: Pediatrics, American Academy of Pediatrics (AAP), Vol. 48, No. 4 ( 1971-10-01), p. 657-662
    Abstract: The purpose of this statement is to provide a progress report concerning the activities and accomplishments of the Committee on Indian Health. The Committee was established in late 1964 with the following objectives defined by the Executive Board: 1. To encourage experienced pediatricians to consider careers within the Indian Health Service. 2. To conduct or sponsor studies of special pediatric problems in Indian and Alaskan natives. 3. To provide leadership in the review and development of methods and procedures to improve the provision of pediatric services to the Indian and Alaskan native population. 4. To stimulate continuing individual and organizational interest in the Indian Health Program by pediatricians, particularly those in practice in areas with a large Indian population. 5. To establish a continuing liaison and professional relationship between the Academy and pediatricians assigned to the Indian Health Program. COMMITTEE ACTIVITIES Meetings Since its inception, the Committee has held formal meetings in Phoenix, Anchorage, Billings, Chicago, Washington, Albuquerque, Tucson, and Oklahoma City. Members of the Committee are physicians who are informed and interested in Indian health and who reside near Indian or Alaskan native populations. The Committee has seen the problems of American Indians and Alaskan natives firsthand during field trips to reservations and other locations with concentrations of Indian populations. Shortly after its establishment, the Committee saw the need to maintain continuing liaison with other committees and agencies. Therefore, a consultant from the National Institute of Child Health and Human Development was named to the Committee, and a liaison representative from the Committee on School Health of the Academy was added as a consultant.
    Type of Medium: Online Resource
    ISSN: 0031-4005 , 1098-4275
    Language: English
    Publisher: American Academy of Pediatrics (AAP)
    Publication Date: 1971
    detail.hit.zdb_id: 1477004-0
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  • 4
    In: Pediatrics, American Academy of Pediatrics (AAP), Vol. 48, No. 6 ( 1971-12-01), p. 990-992
    Abstract: The frequent use of marijuana by American youth has compelled the Committee on Drugs to explore the present methods of and recommendations for controlling marijuana. On October 15, 1970, the Executive Board of the American Academy of Pediatrics endorsed in principle a statement on marijuana which was prepared by the Massachusetts Chapter of the Academy and published in the Academy's Newsletter.1 This statement called for considering possession of marijuana as a misdemeanor rather than a felony, but it was against legalizing use of marijuana at the present time. On October 27, 1970, President Nixon signed into law the Comprehensive Drug Abuse, Prevention and Control Act of 1970 (P.L. 91-513). This law became effective May 1, 1971; it is the Federal Government's attempt to control drug abuse by scientific and medical measures (under control of the Department of Health, Education, and Welfare) and by law enforcement activities (Department of Justice). The new Federal law has stopped short of legalizing marijuana, but it does allow a judge the discrelion to withhold criminal charges for the first offense of possession. The Massachusetts Chapter notes2 that marijuana is not a narcotic and does not produce addiction. Short-term physical effects are innocuous. However, impaired performance on simple intellectual and psychomotor tests is seen after individuals have smoked marijuana for the first time; but, such effects are not seen in regular users. There is no evidence to substantiate the common misconceptions that use of marijuana leads to crime or addiction to opiates. But, so little scientific information is available on the long-term use of marijuana that it should be considered a potentially harmful drug.
    Type of Medium: Online Resource
    ISSN: 0031-4005 , 1098-4275
    Language: English
    Publisher: American Academy of Pediatrics (AAP)
    Publication Date: 1971
    detail.hit.zdb_id: 1477004-0
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  • 5
    In: Pediatrics, American Academy of Pediatrics (AAP), Vol. 56, No. 5s ( 1975-11-01), p. 955-956
    Abstract: The Committee on Drugs unites with the Joint Committee on Physical Fitness, Recreation, and Sports Medicine in condemning the use of drugs to improve athletic performance, However, the Committee on Drugs would like to clearly distinguish between the promiscuous use of drugs and their pharmacologic use to control a specific disease state enabling the adolescent to participate in sports, for example, the use of insulin for diabetes, anticonvulsants for epilepsy, digitalis for heart disease, or bronchodilators for asthma. Children and adolescents with handicaps should be given the same advantages as other children, including participation in athletic activities. Athletes with medical conditions controlled by drugs should not be placed in the same category as youths taking drugs for other purposes, and there should be minimal, if any, restrictions imposed on them. One recent example of the type of restrictions which should not be imposed is the athlete with exercise-induced bronchoconstriction who was disqualified in the 1972 Olympics in Munich because he used a bronchodilator prescribed by his physician. Exercise-induced bronchospasm is a common handicap of allergic youth, and may occur in between 60% and 80% of individuals with allergic respiratory distress.1 Such bronchoconstriction can be modified by the administration of theopylline, theophylline epherdrine combinations,3 or cromolyn sodium,4, 5 The Committee on Children with Handicaps also recommends that children with asthma participate in sports and physical education and that every effort be made to minimize restrictions.6 At the annual meeting of the American Academy of Allergy in Washington, D.C., February 14, 1973, the following resolution was approved unanimously: "Participants in competitive athletics with asthma and other allergic conditions should not be disqualified because of the use, with medical supervision, of therapeutic doses of ephednine before and during athletic competition."7
    Type of Medium: Online Resource
    ISSN: 0031-4005 , 1098-4275
    Language: English
    Publisher: American Academy of Pediatrics (AAP)
    Publication Date: 1975
    detail.hit.zdb_id: 1477004-0
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  • 6
    In: Pediatrics, American Academy of Pediatrics (AAP), Vol. 48, No. 6 ( 1971-12-01), p. 988-989
    Abstract: Published reports and unpublished communications to the Committee on Drugs of the American Academy of Pediatrics indicate that substances potentially hazardous to the premature and full-term newborn infant continue to be used in the laundering of clothing, diapers, and bedding for hospital nurseries. In 1962 the Subcommittee on Accidental Poisoning called attention to occurrences of methemoglobinemia in premature and full-term newborn infants whose diapers were autoclaved after a final laundry rinse with the bacteriostatic agent, 3-4-4' trichlorocarbanilide (TCC).1 Subsequent reports in the pediatric literature confirmed and added to these "epidemics" of neonatal methemoglobinemia2-4 and suggested that aniline–a wellknown cause of methemoglobinemia5–resulting from the break-down of TCC during autoclaving, was absorbed from diapers and other nursery clothing through the skin of the infants. Although direct proof of the etiologic role of TCC is lacking, the association is of sufficient concern that the forthcoming Academy manual, Standards and Recommendations for Hospital Care of Newborn Infants, Second Edition, makes reference to the hazards of using TCC. Although a limited and informal survey of hospital nurseries in the United States and Canada indicates that most hospital laundry procedures have abandoned TCC in treating clothing and bed linens of newborn infants, sporadic instances of neonatal methemoglobinemia associated with exposure to this substance still come to the attention of local, state, and national health agencies, manufacturers, and the Committee on Drugs. In 1967, deaths and severe illness occurred in epidemic form in the newborn nursery of a small Midwestern maternity hospital.6 Investigation revealed that the sodium salt of pentachlorophenol (PCP)— which was present in the antimicrobial neutralizer product used in the final rinse of the laundry process for diapers, infant undershirts, and crib linens for the nursery–intoxicated babies by percutaneous absorption.7
    Type of Medium: Online Resource
    ISSN: 0031-4005 , 1098-4275
    Language: English
    Publisher: American Academy of Pediatrics (AAP)
    Publication Date: 1971
    detail.hit.zdb_id: 1477004-0
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  • 7
    In: Pediatrics, American Academy of Pediatrics (AAP), Vol. 51, No. 2 ( 1973-02-01), p. 302-305
    Abstract: The abuse of amphetamines has become a problem of international significance. Japan was the first country to recognize this problem, and by 1954 there were an estimated 500,000 to 600,000 abusers in Japan. More than ten years ago Japan banned the use of amphetamines. The United Kingdom restricted distribution of amphetamines to hospital pharmacies in 1968. Sweden categorized amphetamine as a narcotic in 1944 because of abuse; and in 1965 phenmetrazine (Preludin) and in 1968 methylphenidate (Ritalin) were removed from the market. Patients now requiring amphetamines are registered with the government. Sweden has about 10,000 drug addicts (almost all between 15 and 30 years of age) using central stimulants intravenously; this is about the same percentage of their population as the estimated percentage of heroin addicts in New York City.1 In contrast, the number of heroin and opiate addicts in Sweden is estimated to be less than 500. In 1970, the Food and Drug Administration (FDA) responded to the problem of amphetamine abuse in the United States by limiting the package insert labeling for amphetamines to three indications: narcolepsy, hyperkinesis in children, and the short-term treatment of obesity. Currently, the latter indication is being reviewed and may no longer be valid. Among the related agents there is some specificity in labeling, e.g., methylphenidate is approved for use in adults with mild depression, narcolepsy at any age, and children with minimal brain dysfunction but not obesity; phenmetrazine for use only in obesity, etc. However, in the broad view there is a similarity in the pharmacologic properties, side effects, and abuse liability of dextro-amphetamine, methamphetamine, methylphenidate, and phenmetrazine.
    Type of Medium: Online Resource
    ISSN: 0031-4005 , 1098-4275
    Language: English
    Publisher: American Academy of Pediatrics (AAP)
    Publication Date: 1973
    detail.hit.zdb_id: 1477004-0
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  • 8
    In: Pediatrics, American Academy of Pediatrics (AAP), Vol. 51, No. 2 ( 1973-02-01), p. 297-299
    Abstract: One of the most important concepts in pediatric pharmacology is that exposure to drugs or chemicals may have latent, unforeseen effects on the child later in life. Some of the most dramatic occurrences, other than teratogenesis, are those in which hormonal exposure during the fetal or newborn period alters adult sexual development. However, none of these episodes is more impressive and ominous than that reported by Herbst et al.1 Herbst, an obstetrician at the Massachusetts General Hospital, was intrigued by the presentation of seven patients with adenocarcinoma of the vagina, an extremely rare tumor not previously seen at the hospital. The patients ranged in age from 14 to 22 years and sought medical advice because of vaginal bleeding. Several had benign adenosis, suggesting that the malignant change seen in all was based on a fundamental alteration in the biology of the vaginal epithelium. Six of the patients were treated with radical surgery, and one was treated with wide, local excision. One of the patients died after surgery. In what could serve as a model of a scientifically conducted, epidemiologic study, each of the seven patients, plus an additional patient from another hospital, was matched with four controls born in the same hospital within four days. Thus, the "control" group was chosen in a manner to eliminate many biases of artificially contrived control populations. A wide variety of possible influences in both mothers and offspring were considered, e.g., maternal age, smoking habits, exposure to X-rays, breast-feeding, birth weight, age at menarche, medications during pregnancy, and so forth.
    Type of Medium: Online Resource
    ISSN: 0031-4005 , 1098-4275
    Language: English
    Publisher: American Academy of Pediatrics (AAP)
    Publication Date: 1973
    detail.hit.zdb_id: 1477004-0
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  • 9
    In: Pediatrics, American Academy of Pediatrics (AAP), Vol. 44, No. 5 ( 1969-11-01), p. 766-767
    Abstract: About 10% of short patients referred for endocrine consultation have hypopituitarism. This may be in the form of growth hormone deficiency in association with the loss of other pituitary trophic hormones or isolated growth hormone deficiency. For treatment of these patients, pediatricians inquire whether human growth hormone (HGH) is available and what growth response will result from its administration. Excellent responses in augmenting somatic growth and controlling hypoglycemia in the treatment of growth hormone deficiency have been obtained with intramuscular injections of HGH. Growth rates increase to supranormal levels, permitting "catch up" growth in amounts as much as 15 cm per year during therapy. It is frequently necessary to treat with HGH for several years, since the hypopituitary patient is usually well below the 3rd percentile in height at the time of diagnosis. The minimum amount of HGH required would at present seem to be of the order of 3 units per week. Since most HGH preparations have a potency of the order of 1 unit or less per milligram, and the human pituitaries from which HGH is extracted yield from 3 to 5 mg (depending on the extraction procedure), many pituitaries are required to treat each patient. The increasing availability of growth hormone immunoassay has made it possible to diagnose growth hormone deficiency relatively easily; therefore, the number of children who need therapy has increased considerably. However, the supply of growth hormone is still entirely dependent on the collection and extraction of human pituitaries. This laborious procedure has not been able to keep up with the increasing demand for the hormone.
    Type of Medium: Online Resource
    ISSN: 0031-4005 , 1098-4275
    Language: English
    Publisher: American Academy of Pediatrics (AAP)
    Publication Date: 1969
    detail.hit.zdb_id: 1477004-0
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  • 10
    Online Resource
    Online Resource
    Southern Medical Association ; 1973
    In:  Southern Medical Journal Vol. 66, No. 4 ( 1973-04), p. 401-404
    In: Southern Medical Journal, Southern Medical Association, Vol. 66, No. 4 ( 1973-04), p. 401-404
    Type of Medium: Online Resource
    ISSN: 0038-4348
    Language: English
    Publisher: Southern Medical Association
    Publication Date: 1973
    detail.hit.zdb_id: 2031166-7
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