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  • 1
    Online Resource
    Online Resource
    Sir Syed College of Education ; 2023
    In:  sjesr Vol. 6, No. 2 ( 2023-06-22), p. 71-84
    In: sjesr, Sir Syed College of Education, Vol. 6, No. 2 ( 2023-06-22), p. 71-84
    Abstract: In the middle- and low-income developing countries like Pakistan treatment of diabetes is very expensive and people can’t afford the cost of medications in this way households face many financial hardships. Therefore, the study was focused on how cultural myths influence the patients in managing diabetes at household level to avoid the use of medications. The purpose of this research is to study the relationship of treatment cost and household budget and further to explore the cultural myths in regards to managing diabetes. The study was carried out in Cantonment area of Rawalpindi city. Further the research study was qualitative in nature and selecting 20 diabetic patients through purposive sampling technique of non-probability sampling type. Moreover, for this study research methodology was exploratory and data were collected through face-to-face interview. Interview has been recorded with due permission of the respondents and transcribed in order to analyze or generate various themes. In this study findings identified in six theme, mode of treatment, affordability of treatment, bearing of expenditure, budget disturbance, Cultural belief and practices, and Cultural myths in management of diabetes. these were found that patients who bear expenses on self without any health insurance or not having any panel of hospital facing issue to manage the diabetes. Due to costly medicines their household budget was badly disturbed and most of them let the visit of doctor, use medication only once in a day just to pass the whole month from these medicines. Further most of the patients never conduct hba1c test regularly and the reason is non-affordability of test cost. Only those who are on the panel of certain hospitals conduct this test after every three months. Furthermore, due to costly medications patients looking for alternative solutions as they choose cultural belief and myths to control diabetes just to satisfy the self.
    Type of Medium: Online Resource
    ISSN: 2706-6525 , 2706-8285
    URL: Issue
    Language: Unknown
    Publisher: Sir Syed College of Education
    Publication Date: 2023
    detail.hit.zdb_id: 3077925-X
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  • 2
    Online Resource
    Online Resource
    National University of Sciences and Technology ; 2022
    In:  NUST Journal of Natural Sciences Vol. 6, No. 2 ( 2022-02-28)
    In: NUST Journal of Natural Sciences, National University of Sciences and Technology, Vol. 6, No. 2 ( 2022-02-28)
    Abstract: Depression affects an individual’s feelings, thoughts, and behavior. It is known as the most common mental illness worldwide with complex origin. The risk factors for depression include both genetic as well as environmental factors. Depression is affecting more than 300 million individuals globally and is categorized as a major cause of the global burden of disease. Several studies demonstrate the involvement of the brain-derived neurotrophic factor (BDNF) gene in the etiology of depressive disorder. This study was designed to assess the association of (rs6265/G196A) polymorphism of the BDNF gene in the pathogenesis of depression. The cross-sectional study was conducted consisting of 357 samples from Rawalpindi, Pakistan. Depression was determined through questionnaire, using DSM-Ⅳ (Diagnostic and Statistical Manual for Mental Disorders-Version Ⅳ). DNA was extracted from the blood samples of study participants. The conventional polymerase chain reaction was performed to amplify the BDNF gene and to detect the frequency of rs6265/ G196A SNP in the samples of subjects under study. Statistical analysis was done using Pearson’s Chi-Squared test. It was observed that the homozygous GG genotype is more prevalent in study subjects than the homozygous AA or heterozygous AG genotypes. However, depression is likely to be more prevalent in AA genotype i.e., 37.8%, less prevalent in AG genotype i.e., 34.0%, and least prevalent in GG genotype i.e., 28.2%. This data shows the A allele of the BDNF gene to be more associated with depression than the G allele, suggesting this polymorphism to be a somewhat potential target for anti-depressants.
    Type of Medium: Online Resource
    ISSN: 2710-222X , 2072-4659
    URL: Issue
    Language: Unknown
    Publisher: National University of Sciences and Technology
    Publication Date: 2022
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  • 3
    In: Applied Nanoscience, Springer Science and Business Media LLC, Vol. 12, No. 11 ( 2022-11), p. 3237-3249
    Type of Medium: Online Resource
    ISSN: 2190-5509 , 2190-5517
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2607723-1
    detail.hit.zdb_id: 2720219-7
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  • 4
    Online Resource
    Online Resource
    Bentham Science Publishers Ltd. ; 2021
    In:  Current Chinese Science Vol. 1, No. 6 ( 2021-11), p. 595-607
    In: Current Chinese Science, Bentham Science Publishers Ltd., Vol. 1, No. 6 ( 2021-11), p. 595-607
    Abstract: COVID-19 or SARS-CoV-2 or 2019-nCov is a pandemic disease that occurred in December 2019 in Wuhan, Hubei Province of China. It was first transmitted from the animal host to a human source, after which it followed human-human transmission and spread exponentially worldwide. Various countries have fallen prey to this virus, but there are certain countries or populations, which have been more affected by this than others. Moreover, the demographics of transmission and affected individuals are also variable from country-country. The purpose of this article is to highlight the non-modifiable risk factors for COVID-19 and their analysis in various populations affecting their susceptibility. Besides age, gender, and blood group, two major genetic factors associated with this disease are discussed here, including the potential of IL-6, in causing chronic disease conditions and the rs1800795 G/C-174 IL-6 polymorphism in the IL-6 gene and with the potential role of ACE-2 receptor in viral transmission and pathogenicity with its protective and disease-causing variants.
    Type of Medium: Online Resource
    ISSN: 2210-2981
    Language: English
    Publisher: Bentham Science Publishers Ltd.
    Publication Date: 2021
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