In:
Journal of Heterocyclic Chemistry, Wiley, Vol. 55, No. 9 ( 2018-09), p. 2061-2068
Abstract:
A series of novel imidazo[4,5‐ b ]pyridine derivatives were designed and synthesized. The structures of all the newly synthesized compounds were identified by spectroscopic data NMR, MS, and elemental analysis. Bioassay showed that the compounds exhibited potent fungicidal activities against Erysiphe graminis , Puccinia polysora , and so forth. Particularly, 2‐chloro‐5‐((5‐methoxy‐2‐(2‐(trifluoromethyl)phenyl)‐3 H ‐imidazo[4,5‐ b ]pyridin‐3‐yl)methyl)thiazole ( 9b ) displayed fungicidal potency against P . polysora . Its EC 50 value: 4.00 mg/L is comparable with that of tebuconazole. The structure–activity relationship for the target compounds is discussed.
Type of Medium:
Online Resource
ISSN:
0022-152X
,
1943-5193
Language:
English
Publisher:
Wiley
Publication Date:
2018
detail.hit.zdb_id:
2042274-X
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