In:
Canadian Journal of Chemistry, Canadian Science Publishing, Vol. 85, No. 3 ( 2007-03-01), p. 184-188
Abstract:
Zirconium tetrachloride efficiently catalyzes the cyclocondensation reaction of o-phenylenediamine and a ketone in refluxing 1,2-dichloroethane to afford the corresponding 2,3-dihydro-1H-1,5-benzodiazepine in high yield. The formation of specific regioisomers and their structural elucidation are reported for the first time.Key words: zirconium tetrachloride, o-phenylenediamines, ketones, 1,5-benzodiazepines, 1 H NMR, regioisomers.
Type of Medium:
Online Resource
ISSN:
0008-4042
,
1480-3291
Language:
English
Publisher:
Canadian Science Publishing
Publication Date:
2007
detail.hit.zdb_id:
1482256-8
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