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  • 1
    In: Diabetes, Obesity and Metabolism, Wiley, Vol. 20, No. 3 ( 2018-03), p. 629-637
    Abstract: To determine whether baseline metabolic syndrome (MetS) modifies the effect of intensive blood pressure control on cardiovascular (CV) outcomes, and whether the effects varied by race/ethnicity. Methods We performed post hoc analyses among non‐Hispanic black, non‐hispanic white and Hispanic participants, with and without MetS, in the Systolic Blood Pressure Intervention Trial (SPRINT), who were randomized to a systolic blood pressure (SBP) target of 〈 120 mm Hg (intensive group, N = 4544) or an SBP target of 〈 140 mm Hg (standard group, N = 4553). The median follow‐up was 3.26 years. The primary outcome was the composite of the first occurrence of myocardial infarction, stroke, heart failure, non‐myocardial infarction acute coronary syndrome or CV death. Results Overall, 3521/9097 participants (38.7%) met the criteria for MetS at baseline. Baseline characteristics were similar in the two SBP target groups within each MetS subgroup, except body mass index was slightly higher in the standard arm of the MetS subgroup (33.3 ± 5.6 vs 33.0 ± 5.3 kg/m 2 ; P   〈  .01), but were similar across treatment arms in the non‐MetS subgroup. The hazard ratio for the primary outcome was similarly reduced in participants with or without baseline MetS: 0.75 (95% confidence interval [CI] 0.57, 0.96) and 0.71 (95% CI 0.57, 0.87), respectively (adjusted P value for treatment by subgroup interaction = .98). Similarly, there was no evidence of treatment × MetS subgroup interaction for all‐cause mortality (adjusted interaction P value = .98). The findings were also similar across race/ethnic subgroups. Conclusions In this analysis the CV benefit of intensive SBP control did not differ among participants by baseline MetS status, regardless of race/ethnicity.
    Type of Medium: Online Resource
    ISSN: 1462-8902 , 1463-1326
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2018
    detail.hit.zdb_id: 2004918-3
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  • 2
    Online Resource
    Online Resource
    Lahore Garrison University ; 2020
    In:  Journal of English Language, Literature and Education Vol. 2, No. 02 ( 2020-11-18), p. 35-62
    In: Journal of English Language, Literature and Education, Lahore Garrison University, Vol. 2, No. 02 ( 2020-11-18), p. 35-62
    Abstract: This study explores the multiple identities of men and women in English proverbs and power relationships depicted through these identities. This research has not only discussed the representation of female gender but also covered male gender along with relationship shown between both genders in proverbs. 38 proverbs collected from two dictionaries are analyzed through the 3D model of Fairclough. All proverbs are divided into three major categories i.e., proverbs for women, proverbs for men and proverbs involving both genders. Proverbs involving women over numbered those mentioning men. Majority of the proverbs containing women have derogatory remarks for them whereas men are presented with positive connotations. A few proverbs explained the link between men and women in the form of negative and positive dependence. Proverbs involving women display a glimpse of patriarchy by portraying women as a burden, sexual object and fragile. Men on the other hand are explicitly nominated as a gender that owns the world. These proverbs are delivering such power relationships to generations and this could be one of the reasons patriarchies in different forms is still observed in the world. Studying these proverbs about their origins will further help in understanding the picture of genders in English society and how the picture has evolved socially.
    Type of Medium: Online Resource
    ISSN: 2710-4923 , 2663-3485
    Language: Unknown
    Publisher: Lahore Garrison University
    Publication Date: 2020
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  • 3
    In: Human Vaccines & Immunotherapeutics, Informa UK Limited, Vol. 18, No. 6 ( 2022-11-30)
    Type of Medium: Online Resource
    ISSN: 2164-5515 , 2164-554X
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2664177-X
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  • 4
    In: Annals of Laboratory Medicine, Annals of Laboratory Medicine, Vol. 37, No. 2 ( 2017-03-01), p. 151-154
    Type of Medium: Online Resource
    ISSN: 2234-3806 , 2234-3814
    Language: English
    Publisher: Annals of Laboratory Medicine
    Publication Date: 2017
    detail.hit.zdb_id: 2677441-0
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  • 5
    Online Resource
    Online Resource
    Saran Publications ; 2021
    In:  International Journal of Zoological Investigations Vol. 7, No. 2 ( 2021-11-21), p. 772-778
    In: International Journal of Zoological Investigations, Saran Publications, Vol. 7, No. 2 ( 2021-11-21), p. 772-778
    Type of Medium: Online Resource
    ISSN: 2454-3055
    Language: Unknown
    Publisher: Saran Publications
    Publication Date: 2021
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  • 6
    Online Resource
    Online Resource
    Informatics Publishing Limited ; 2021
    In:  Journal of Natural Remedies Vol. 21, No. 4 ( 2021-10-01), p. 265-
    In: Journal of Natural Remedies, Informatics Publishing Limited, Vol. 21, No. 4 ( 2021-10-01), p. 265-
    Abstract: The spectacular thrust and inquisitiveness of the present-day world have resulted in an incredible scientific approach regarding herbal medicine potential. The importance of herbal medicine has witnessed a tremendous expansion because of its significant effective and safe medications, especially in chronic and long-standing ailments. 〈 em 〉 Filfil daraz 〈 /em 〉 ( 〈 em 〉 Piper longum 〈 /em 〉 L.) or long pepper, is a herb with enormous therapeutic benefits. Its beneficial actions are 〈 em 〉 HÄá¸im 〈 /em 〉 (digestive), 〈 em 〉 MuqawwÄ«-i-MiÊ»da 〈 /em 〉 (stomachic), and 〈 em 〉 KÄsir-i- RiyÄḥ 〈 /em 〉 (carminative). Since ages, Unani physicians used this herb for several disorders like 〈 em 〉 BalghamÄ« khansi 〈 /em 〉 (Phlegmatic cough), 〈 em 〉 FÄlij 〈 /em 〉 (Paralysis), 〈 em 〉 Laqwa 〈 /em 〉 (Facial palsy), 〈 em 〉 Mirgi 〈 /em 〉 (Epilepsy), 〈 em 〉 Niqris 〈 /em 〉 (Gout), 〈 em 〉 ‘Irq al-NasÄ 〈 /em 〉 (Sciatica), and 〈 em 〉 QÅ«lanj 〈 /em 〉 (Colitis) etc. Literature survey revealed countless important phytoconstituents namely alkaloids such as piperine, volatile oil, esters and resins. Moreover, many plant parts have shown distinct activities like analgesic, anti-microbial, anti-fungal, immunomodulatory activities in quite a lot of 〈 em 〉 in-vivo 〈 /em 〉 and 〈 em 〉 in-vitro 〈 /em 〉 studies. The present review delivers a comprehensive description of 〈 em 〉 Piper longum 〈 /em 〉 L., its ethnobotanical uses, and recent scientific studies. New research avenues are open for future research endeavours for phytochemical studies and preclinical and clinical trials to explore its medicinal importance.
    Type of Medium: Online Resource
    ISSN: 2320-3358 , 0972-5547
    Language: Unknown
    Publisher: Informatics Publishing Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2729212-5
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  • 7
    Online Resource
    Online Resource
    Medip Academy ; 2022
    In:  International Journal of Reproduction, Contraception, Obstetrics and Gynecology Vol. 11, No. 11 ( 2022-10-28), p. 3018-
    In: International Journal of Reproduction, Contraception, Obstetrics and Gynecology, Medip Academy, Vol. 11, No. 11 ( 2022-10-28), p. 3018-
    Abstract: Background: More recently there has been growing concern that more marginal degrees of thyroid dysfunction particularly subclinical hypothyroidism (elevated TSH and normal T4 concentration) and isolated hypothyroxinemia (normal TSH and low T4) are associated with fetal loss, prematurity and impaired offspring cognitive function and potential risk for fetal loss. Thus, it would seem logical to systematically screen pregnant woman for thyroid disorders. This study focuses specifically on thyroid screening in first trimester of pregnancy.Methods: This is a prospective cross-sectional study over 18 months (December 2020 to June 2022) in 300 patients attending the department of obstetrics and gynecology of teaching hospital attached to Khaja Bandanawaz Institute of Medical Sciences (KBNIMS), KBN University, Gulbarga for antenatal check-up during first trimester of pregnancy.Results: As per our study prevalence of thyroid disorder 14%, subclinical hyperthyroidism 3.67% and subclinical hypothyroidism 10.33%.Conclusions: According to data of our study, it is very ideal to subject all pregnant women for thyroid screening in first trimester with special emphasis to pregnant women in extremes of age, extremes of BMI, bad obstetric history and adverse outcome in previous pregnancy as it shows significant relationship with risk of having thyroid abnormalities.
    Type of Medium: Online Resource
    ISSN: 2320-1789 , 2320-1770
    Language: Unknown
    Publisher: Medip Academy
    Publication Date: 2022
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  • 8
    In: British Journal of Surgery, Oxford University Press (OUP), Vol. 110, No. 7 ( 2023-06-12), p. 804-817
    Abstract: Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries.
    Type of Medium: Online Resource
    ISSN: 0007-1323 , 1365-2168
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2023
    detail.hit.zdb_id: 2006309-X
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  • 9
    Online Resource
    Online Resource
    Lahore Medical and Dental College ; 2022
    In:  Pakistan Journal of Medical and Health Sciences Vol. 16, No. 10 ( 2022-10-30), p. 91-94
    In: Pakistan Journal of Medical and Health Sciences, Lahore Medical and Dental College, Vol. 16, No. 10 ( 2022-10-30), p. 91-94
    Abstract: Background: Adolescence is a time of rapid development in many facets of an individual’s physiological, cognitive, and interpersonal traits, but it also comes with some complexities. Aim: To evaluate the level of participation in different domains of life situations in adolescents with Cerebral Palsy. Study design: Cross-sectional study. Methodology: Study conducted in adolescents with Cerebral Palsy between age 10 – 19, with motor impairment level I, II and level III on GMFCS. Sample size was 84 participants. Questionnaire of Young People’s Participation (QYPP) was used to evaluate participation in different activities and domains of life. Statistical analysis: Analysis of data was done by SPSS v.26. Results: The highest percentage score was observed for Autonomy followed by Getting on with other people, Home life, Reception and Leisure and School or College life. The least percentage score was seen for two domains i.e., Work life and Preparing for the future. It was observed that participants in higher age category had higher score except school or college life domain but no significant difference was evident as per p-value. Conclusion: It was concluded that overall frequency of participation levels proved inadequate in adolescents with CP in all the domains tested. Keywords: Adolescents, Cerebral Palsy, Personal Autonomy and Social Participation.
    Type of Medium: Online Resource
    URL: Issue
    Language: Unknown
    Publisher: Lahore Medical and Dental College
    Publication Date: 2022
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  • 10
    Online Resource
    Online Resource
    Institute of Medico-legal Publications Private Limited ; 2022
    In:  Indian Journal of Public Health Research & Development Vol. 14, No. 1 ( 2022-12-16), p. 173-177
    In: Indian Journal of Public Health Research & Development, Institute of Medico-legal Publications Private Limited, Vol. 14, No. 1 ( 2022-12-16), p. 173-177
    Abstract: Background: Preeclampsia is a pregnancy-related condition characterized by high blood pressure and proteinuria after 20 weeks of pregnancy. It’s a multiorgan disorder with no recognized cause. It’s one of the most prevalent pregnancy problems, and it’s a leading cause of maternal and foetal mortality and morbidityObjectives: To determine the placental laterality as a predictor for development of pre-eclampsia.Methods: 100 pregnant women with gestational age between 18 to 24 weeks with h/o pre-eclampsia were included. ultrasonography was used to determine the position of the placenta in all 100 women. When the placenta was evenly divided across the right and left sides of the uterus, regardless of anterior, posterior, or fundal location, it was categorized as central.Results: The mean age group was 23.53 ± 3.15 yrs. The prevalence of pre-eclampsia in this study was 14%. This screening test has Sensitivity of 81%, Specificity of 85.3%, Positive predictive value of 47.2%, Negative predictive value of 96.43%, p value 〈 0.001 which is significant.Conclusion: Placental laterality is an excellent screening tool for the prediction of pre-eclampsia aids in the identification of the individuals particularly at risk, allowing them to be included in a primary prevention programmes
    Type of Medium: Online Resource
    ISSN: 0976-5506 , 0976-0245
    URL: Issue
    Language: English
    Publisher: Institute of Medico-legal Publications Private Limited
    Publication Date: 2022
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