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  • 1
    Online Resource
    Online Resource
    Bangladesh Academy of Sciences ; 2013
    In:  Delta Medical College Journal Vol. 1, No. 1 ( 2013-05-16), p. 3-7
    In: Delta Medical College Journal, Bangladesh Academy of Sciences, Vol. 1, No. 1 ( 2013-05-16), p. 3-7
    Abstract: Backgound: The number of hypogonads is increasing day by day. It may be due to sedentary life style with increased obesity, increased tension or stressed lifestyle among all groups of populations. Visceral obesity is associated with insulin resistance, diabetes mellitus and also with hypogonadism. Objective: This study was carried out to determine the proportion of insulin resistance among male subjects with hypogonadism in different age groups along with status of erectile quality among diabetics and non diabetics. Materials and method: This cross sectional study among 161 adult male subjects aged ? 20 to ? 60 years were purposively selected from Bangladesh Institute of Research and Rehabilitation in Diabetes Endocrine and Metabolic Disorders (BIRDEM), Dhaka, Bangladesh between May 2009 to September 2010. Glycemic status and insulin resistance (by HOMA-R) were done and relevant history were documented. Results: The highest proportion (38.9%) of hypogonadism was in ? 50 years age group whereas highest proportion (39.6%) of the eugonads was in the age group of 40 to 49 years. More than half of the hypogonad subjects had weak erectile quality (54.0%) which were followed by absent erectile quality in 32.7% and 13.3% subjects had normal erectile quality. Among the eugonad subjects 41.7% had normal erectile quality, 41.6% subjects had weak erectile quality and 16.7% subjects had no erectile quality. More than ninety percent of the hypogonad subjects and about 60% of the eugonad subjects had insulin resistance. The average HOMA-R was more in the subjects with hypogonadism with diabetes which was highly significant (p-value 〈 0.001). Conclusion: Hypogonadism is associated with insulin resistance.DOI: http://dx.doi.org/10.3329/dmcj.v1i1.14968 Delta Med Col J. Jan 2013;1(1):3-7 
    Type of Medium: Online Resource
    ISSN: 2308-460X , 2307-6615
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2013
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  • 2
    Online Resource
    Online Resource
    Bangladesh Academy of Sciences ; 2013
    In:  Delta Medical College Journal Vol. 1, No. 2 ( 2013-07-29), p. 37-41
    In: Delta Medical College Journal, Bangladesh Academy of Sciences, Vol. 1, No. 2 ( 2013-07-29), p. 37-41
    Abstract: Background: Diabetic retinopathy is the commonest complication that occurs from the very beginning in patients with diabetes mellitus (DM). DM itself leads to increased homocysteine (Hcy) level. It is postulated that hyperhomocysteinaemia causes retinal vascular damage as Hcy is an established vasculotoxic agent and auto-oxidation of Hcy leads to oxidative stress, endothelial dysfunction, platelet activation and thrombus formation. Objective: The aim of the study was to evaluate the serum Hcy in newly diagnosed type 2 diabetic subjects with diabetic retinopathy. Materials and method: A case control study was carried out in the department of Biochemistry, Bangabandhu Sheikh Mujib Medical University, Dhaka, during the period of January 2006 to December 2007. Total 85 newly diagnosed type 2 diabetic subjects were included in this study, 40 were case having retinopathy and 45 were age and sex matched control without retinopathy. Serum Hcy was measured and compared between case and control. Results: Serum Hcy level in cases was significantly higher (p 〈 0.05) compared to that of control (15.11±5.49 ?mol/L vs. 12.59±4.01 ?mol/L). Odds ratio was also determined for hyperhomocysteinemia (OR=2.23; CI 0.9-5.45). Conclusion: Hyperhomocysteinaemia is associated with diabetic retinopathy in newly diagnosed type 2 diabetes. DOI: http://dx.doi.org/10.3329/dmcj.v1i2.15916 Delta Med Col J. Jul 2013;1(2):37-41
    Type of Medium: Online Resource
    ISSN: 2308-460X , 2307-6615
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2013
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  • 3
    Online Resource
    Online Resource
    Bangladesh Academy of Sciences ; 2022
    In:  Bangladesh Medical Research Council Bulletin Vol. 48, No. 1 ( 2022-09-05), p. 33-40
    In: Bangladesh Medical Research Council Bulletin, Bangladesh Academy of Sciences, Vol. 48, No. 1 ( 2022-09-05), p. 33-40
    Abstract: Background: Kidney recipients constitute a vulnerable group of population and may have high risk of morbidity and mortality when infected with COVID-19. Objective: To a assess the overall outcome as well as the incidence and impact of COVID-19 among recipients who underwent transplantation during the pandemic Methods: A pre-designed follow up protocol was set to prospectively analyse the data obtaining from the recipients who underwent renal transplantation since 8 March 2010, the first appearance of COVID-19 in Bangladesh till 31 December, 2020. Outcome parameters were renal functional status; surgical, urological, immunological and medical complications; and incidence of COVID-19 and its outcome during the first 12 weeks post-transplant period. Results: Out of 100 patients, 82.0% were male and 18.0% were female. Serum creatinine levels (μmol/L) at 4, 8 and 12 weeks post-transplant were 200 in 6.0%, 5.0% and 6.0% respectively. Graft nephrectomy was done in 3 cases due to vascular complications. Five (5.0%) patients presented with symptoms of COVID-19, among them, 2 cases were confirmed with RT-PCR. There were 6 death cases, and septicaemia was the most common cause of death. The overall mortality rate was 6.0% in our study population but in COVID-19 confirmed cases it was 50.0%. Conclusion: During this pandemic, the overall outcome of renal transplantation was excellent and the incidence of symptomatic COVID-19 among transplant recipients was not higher than the incidence observed in general population of Bangladesh. But among the COVID-19 confirmed recipients, mortality rate was significantly higher. Bangladesh Med Res Counc Bull 2022; 48(1): 33-40      
    Type of Medium: Online Resource
    ISSN: 2224-7238 , 0377-9238
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2022
    detail.hit.zdb_id: 2491184-7
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  • 4
    Online Resource
    Online Resource
    Bangladesh Academy of Sciences ; 2017
    In:  Delta Medical College Journal Vol. 5, No. 2 ( 2017-07-31), p. 57-62
    In: Delta Medical College Journal, Bangladesh Academy of Sciences, Vol. 5, No. 2 ( 2017-07-31), p. 57-62
    Abstract: Correction: On 10th August 2017 due to typographical errors, the period of the study was changed from May 2016 to June 2017 and the caption of the red segment in Figure 1 was changed from No UTI, 41% to UTI, 59%Background: Urinary tract infection (UTI) is one of the common bacterial infections in mankind. The changing antimicrobial sensitivity in UTI demands use of appropriate antibiotics.Objective: This study was conducted to determine the distribution and antimicrobial susceptibility of uropathogens.Materials and method: This was a prospective study conducted in Bangladesh Medical College & Hospital, Dhaka, Bangladesh between May 2016 and June 2017 to identify the organisms causing UTI and their antibiotic susceptibility. Clean catch midstream urine samples were collected from 95 patients presenting with symptoms of UTI. Antimicrobial susceptibility was performed by disc diffusion method.Results: Out of 95 urine samples, 56 (58.9%) were found positive. The prevalence was significantly higher in females than in males (females: 58.9%; males: 41%). Age group of 〉 48 years showed higher prevalence of UTI. The most common organisms isolated were Escherichia coli, Klebsiella, Pseudomonas, Proteus and Staphylococcus aureus. These represented 44.6%, 21.4%, 14.3%, 12.5%, and 7.14% of isolates respectively. Imipenem and Meropenem were found the most susceptible drug against isolated uropathogens.Conclusion: Most powerful antibiotics in our study were imipenem and meropenem. In conclusion, one can truly affirm that the choice of drugs in the treatment of UTI is becoming quite narrow today due to the wide scale resistance that the common UTI pathogens show to drugs which have been used previously.Delta Med Col J. Jul 2017 5(2): 57-62
    Type of Medium: Online Resource
    ISSN: 2308-460X , 2307-6615
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2017
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  • 5
    Online Resource
    Online Resource
    Bangladesh Academy of Sciences ; 2012
    In:  Journal of Enam Medical College Vol. 1, No. 2 ( 2012-07-29), p. 63-66
    In: Journal of Enam Medical College, Bangladesh Academy of Sciences, Vol. 1, No. 2 ( 2012-07-29), p. 63-66
    Abstract: Background: Diabetic retinopathy is the commonest and usually the first observable vascular complication of diabetes mellitus. Along with hyperglycaemia, dyslipidaemia is a contributing factor for the occurrence of diabetic retinopathy. It is postulated that dyslipidaemia results in formation of hard exudate by increasing blood viscosity and altering the fibrinolytic system. A case control study was carried out in the department of Biochemistry, Bangabandhu Sheikh Mujib Medical University, Dhaka during the period of January 2006 to December 2007 to evaluate the serum lipid profile in newly diagnosed type 2 diabetic subjects with diabetic retinopathy.Materials and Methods: Total 85 newly diagnosed type 2 diabetic subjects were included in this study, 40 were cases having retinopathy and 45 were age and sex matched controls without retinopathy. Serum triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) were compared between cases and controls. Unpaired t-test and chi-square test were done between groups as tests of significance.Results: All the parameters of lipid profile showed dyslipidaemic trend both in cases and controls. In the cases TG was significantly higher and HDL-C was significantly lower than that of controls (p 〈 0.05) whereas no significant difference was found between cases and controls with respect to serum TC and LDL-C.Conclusion: It can be concluded that high TG and low HDL-C are associated with diabetic retinopathy in newly diagnosed type 2 diabetes. DOI: http://dx.doi.org/10.3329/jemc.v1i2.11464 J Enam Med Col 2011; 1(2): 63-66
    Type of Medium: Online Resource
    ISSN: 2304-9316 , 2227-6688
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2012
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  • 6
    Online Resource
    Online Resource
    Bangladesh Academy of Sciences ; 2015
    In:  Journal of Enam Medical College Vol. 5, No. 1 ( 2015-01-08), p. 30-33
    In: Journal of Enam Medical College, Bangladesh Academy of Sciences, Vol. 5, No. 1 ( 2015-01-08), p. 30-33
    Abstract: Background: Diet deficient in fresh fruits and vegetables are associated with an increased risk of coronary diseases. Low levels of vitamin C, vitamin E and other antioxidants may enhance the production of oxidized LDL and are important independent risk factors for coronary disease. Objective: To make a comparative evaluation of lipid profile and atherogenic index of plasma (AIP) between vegetarians and nonvegetarians. Materials and Methods: This case-control study was carried out in the Department of Biochemistry of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka between July 2011 to June 2012. Vegetarian and nonvegetarian subjects of male sex were the study population. Vegetarians were considered as cases while nonvegetarians as controls. After proper ethical consideration a total of 30 vegetarians and 40 nonvegetarians were consecutively included in the study based on predefined inclusion and exclusion criteria. Laboratory investigations were done in the Department of Biochemistry, BSMMU, Dhaka. Results: The vegetarians had significantly lower total cholesterol and LDLcholesterol than the nonvegetarians (p=0.000 and p=0.000 respectively). Serum HDL cholesterol was also lower among the vegetarians (p=0.002) and triglycerides were almost identical in both the groups (p=0.272). Conclusion: The study reveals lower level of total cholesterol, LDLcholesterol and HDL-cholesterol in vegetarians. No difference regarding triglycerides and AIP was found between the groups. So, the findings of this study do not indicate any superiority of vegetarian diet in control and prevention of cardiac diseases. DOI: http://dx.doi.org/10.3329/jemc.v5i1.21494 J Enam Med Col 2015; 5(1): 30-33
    Type of Medium: Online Resource
    ISSN: 2304-9316 , 2227-6688
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2015
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  • 7
    In: Delta Medical College Journal, Bangladesh Academy of Sciences, Vol. 4, No. 2 ( 2016-08-19), p. 71-76
    Abstract: Background: Spinal tuberculosis is a medical disease and antitubercular drugs play the main role in the recovery of patients. However, with proper indication, surgical procedures are superior in the prevention of neurological deterioration, maintenance of stability, early recovery and early mobilization. Modern method of surgical intervention of dorsolumbar tuberculosis is posterior decompression, stabilization with transpedicular screws and rods and fusion.Objective: To evaluate the efficacy of posterior decompression, stabilization by transpedicular screws and rods and fusion in patients with spinal TB in thoracic and lumbar region.Materials and method: This is a prospective interventional study carried out at National Institute of Traumatology & Orthopaedic Rehabilitation (NITOR), Dhaka, Bangladesh and different private hospitals in Dhaka from October, 2012 to December, 2014. Total number of patients was 12; among them 7 were male and 5 were female, age ranged from 21-60 years with a follow up period of 12 months to 18 months.Results: More common site of tubercular lesion was at dorsal spines (58.73%). In this study the patients were preoperatively classified according to American Spinal Injury Association (ASIA) Impairment Scale and among the patients 1 was ASIA- A, 2 were ASIA-B, 5 were ASIA-C, 3 were ASIA-D, and 1 was ASIA-E. In postoperative state 1 patient was ASIA-B, 3 patients were ASIA-D and 8 were ASIA-E. Maximum patients (75%) had bony fusion grade 1. More than 80% subjects had good outcome.Conclusion: Posterior decompression, stabilization with transpedicular screws and rods and fusion is a satisfactory surgical modality of treatment of dorsolumbar spinal tuberculosis.Delta Med Col J. Jul 2016 4(2): 71-76
    Type of Medium: Online Resource
    ISSN: 2308-460X , 2307-6615
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2016
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  • 8
    In: AIP Advances, AIP Publishing, Vol. 11, No. 12 ( 2021-12-01)
    Abstract: In this research, the ability of the leaf extract of Justicia adhatoda is observed as a unique reducing agent for bioconversion of copper ions to copper oxide nanoparticles (CuO NPs). CuO NPs have significant antibacterial activity and nontoxicity toward humans. The formation of nanoparticles is confirmed by the color change of the solution from light blue to brown because of the trouble of surface plasmon resonance (SPR). The optical study showed an SPR peak at 280 nm. The interaction of CuO NPs excipients with the biomolecules is studied using x-ray diffraction and particle size is also calculated. Field emission scanning electron microscopy has been applied to recognize the size, shape, and morphology of nanoparticles, which is incorporated in cotton. Fourier transform infrared spectroscopy showed that the reduction of CuO NPs was due to the biomolecules present in the leaf extract, which acted as reducing, in addition to capping, agents. The synthesized CuO NPs-coated cotton were tested for antibacterial activity to both gram-positive and gram-negative bacterial strains, which are applicable for the fabrication of an antibacterial cotton textile.
    Type of Medium: Online Resource
    ISSN: 2158-3226
    Language: English
    Publisher: AIP Publishing
    Publication Date: 2021
    detail.hit.zdb_id: 2583909-3
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  • 9
    In: Delta Medical College Journal, Bangladesh Academy of Sciences, Vol. 7, No. 1 ( 2019-03-19), p. 11-15
    Abstract: Background: The kidneys have an important role in eliminating the final products of metabolic activities, excreting the drugs and chemicals. A variety of frequently used drugs have been demonstrated to produce nephrotoxic effects. Objective: This study was carried out to observe the effect of vitamin E on gentamicin-induced nephrotoxicity by assessing serum urea level in Long Evans rats. Materials and method: The experimental study was carried out on 40 healthy Long Evans rats of both sex with the weight ranges from 172-255 gm and the age ranges from 7 to 10 weeks. The rats were divided into four groups - Group A (normal control) received normal saline, group B, C and D received gentamicin for 6 days, rats of group C received vitamin E capsule for total 9 days with gentamicin whereas group D received vitamin E capsule for total 10 days with gentamicin. Serum urea level was measured at the end of the experiment. Results: The (mean±SD) serum urea levels in group A, B, C and D were 4.79±0.32, 12.41±1.22, 7.56±1.11 and 7.15±1.09 mmol/L respectively. The differences between groups were highly significant (p 〈 0.001) for group A & B, A & C, A & D, B & C, B & D whereas the difference between C & D (p 〉 0.01) was not significant. Serum urea level of the normal saline control group (group A) was within the normal limit (4.79 mmol/L). Serum urea level in gentamicin treated rats (group B) was more in comparison to gentamicin and vitamin E treated rats (group C & D) and pretreatment with longer duration group (group D) showed lower serum urea value than shorter one (group C) though the groups showed no significant difference. Conclusion: Vitamin E treatment showed some protective effect against gentamicin-induced nephrotoxicity. The results also indicated that effectiveness of vitamin E depends on duration of pretreatment that means the pretreatment duration must be increased to a suitable period for better protection against gentamicin-induced nephrotoxicity. Delta Med Col J. Jan 2019 7(1): 11-15
    Type of Medium: Online Resource
    ISSN: 2308-460X , 2307-6615
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2019
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  • 10
    Online Resource
    Online Resource
    Bangladesh Academy of Sciences ; 2014
    In:  Medicine Today Vol. 25, No. 2 ( 2014-02-10), p. 67-68
    In: Medicine Today, Bangladesh Academy of Sciences, Vol. 25, No. 2 ( 2014-02-10), p. 67-68
    Abstract: Coronary heart disease is the most common form of heart disease and single most important cause of premature death in developed countries. It is estimated that coronary heart disease will become the major cause of death in all regions of the world by 2020. There are several modifiable risk factors of coronary heart disease. Among those diabetes mellitus is one major modifiable risk factor. So we designed this study to see the frequency of diabetes mellitus in patients with coronary heart disease in three tertiary hospitals in Bangladesh with an objective to see the frequency of diabetes mellitus in patients with coronary heart disease. This observational cross-sectional study was conducted in the department of Biochemistry of Bangabandhu Sheikh Mujib Medical University, Dhaka from July 2006 to June 2007. The study was done among 300 purposively selected diagnosed patients of coronary heart disease of both sexes. Diabetes mellitus was diagnosed according to WHO criteria. In this study we found that 23.7% of study subjects had diabetes mellitus. From this study, it can be concluded that the prevalence of diabetes (an important modifiable risk factor) is high in coronary heart disease patients. DOI: http://dx.doi.org/10.3329/medtoday.v25i2.17923 Medicine Today 2013 Vol.25(2): 67-68
    Type of Medium: Online Resource
    ISSN: 2408-8714 , 1810-1828
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2014
    detail.hit.zdb_id: 2573717-X
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