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  • 1
    In: Hirurg (Surgeon), PANORAMA Publishing House, , No. 2 ( 2023-04-19), p. 36-44
    Abstract: The development of gastrointestinal bleeding from erosive and ulcerative defects of the mucous membranes of the upper gastrointestinal tract, which, according to the world literature, occurs in 2–13 % of hospitalized patients with COVID-19, is a multifaceted problem that is still relevant, but has not been adequately reflected in scientific publications. The aim of the work was to study the clinical characteristics of patients with gastrointestinal bleeding on the background of SARS-CoV-2 and evaluate the methods of endoscopic hemostasis. The article analyzed cases of bleeding from the upper gastrointestinal tract in 115 patients suffering from the novel coronavirus infection. The severity of the course of COVID-19 was assessed according to the criteria of the NEWS scale, the degree of respiratory failure, and radiological data. 114 out of 115 patients had comorbidities; the most common diseases were cardiovascular diseases, endocrine pathology, chronic kidney disease, and oncopathology. The most common sources of bleeding (82 %) were acute or chronic ulcers of the stomach and/or duodenum against the background of erosive hemorrhagic lesions of the mucosa. The following methods of endoscopic hemostasis were used: endoscopic clipping, endoscopic injections, applications of hemostatic agents and solutions, and combined methods which were used more often. Hemostasis was achieved in all cases. Repeated bleeding occurred in 22 cases (19.1 %) with subsequent achievement of endo-hemostasis. Mortality was 66.95 % (77 patients), with such causes of adverse outcomes as increasing multiple organ failure, respiratory distress syndrome, and septic shock.
    Type of Medium: Online Resource
    ISSN: 2074-0190
    URL: Issue
    Language: Unknown
    Publisher: PANORAMA Publishing House
    Publication Date: 2023
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  • 2
    Online Resource
    Online Resource
    RPO Surgical Society - Wound and Wound Infections ; 2022
    In:  Wounds and wound infections. The prof. B.M. Kostyuchenok journal Vol. 8, No. 4 ( 2022-06-07), p. 24-29
    In: Wounds and wound infections. The prof. B.M. Kostyuchenok journal, RPO Surgical Society - Wound and Wound Infections, Vol. 8, No. 4 ( 2022-06-07), p. 24-29
    Abstract: An open wound on the head is an injury (skin tear) of all scalp external layers including dermis, subcutaneous fatty tissue, aponeurosis, muscles, vessels and nerves with intact skull bones and intact neurological reactions [1]. Extensive wounds of the external head layers, in addition to a standard threat to the human health, bear an additional risk due to their close localization to the brain. Because of the abundant blood supply to scalp soft tissues, high rate of volumetric blood flow (50–60 milliliters per 100 g of brain tissue), numerous extra-, intracranial arterial and venous anastomoses, there is a real danger of spreading the infection inside the skull and developing meningitis or encephalitis. Problems of care of patients with extensive head wounds, risk of complications that can cause severe consequences determine the relevance of the issue presented in this work. Objective. To analyze treatment results of patients admitted to the emergency department of Mariinskaya State City Hospital in St. Petersburg within three months in 2021 and to develop an optimal tactics for treating patients with extensive wounds of the scalp. Material and research methods. 2245 patients with various types of head injury were admitted to the hospital; 610 (27.2 %) of them had damage of the external scalp layers. Each patient had standard clinical and laboratory examination and multislice computed tomography (MSCT) examination of the head at 64-slice Definition AS (Siemens, Germany) CT scanner. In the emergency department, all patients who were injured by high-energy traumatic objects had the primary surgical debridement; all patients who were injured by low-energy traumatic objects had wound toilet and wound suturing. Three most representative cases with extensive wounds of the external scalp (over 10 cm) with illustrations are presented in the article as clinical examples. Results. All patients had good outcomes. There were no any signs of wound infection either. Conclusion. A thorough primary surgical debridement of scalp wounds with their drainage followed by observation and treatment in the hospital is a necessary condition for successful healing of large scalp wounds.
    Type of Medium: Online Resource
    ISSN: 2500-0594 , 2408-9613
    Language: Unknown
    Publisher: RPO Surgical Society - Wound and Wound Infections
    Publication Date: 2022
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  • 3
    In: Journal Infectology, SPRIDA, Vol. 14, No. 3 ( 2022-10-21), p. 45-49
    Abstract: Today the new coronavirus infection remains one of the most important problems of modern medicine. Among patients requiring hospital treatment, the development of various extrapulmonary complications is quite common. The work is devoted to the study of spontaneous hematomas of various localization against the background of a severe course of a new coronavirus infection treated in an infectious hospital in the period from 2020 to 2021. During the selected time, 17 patients had spontaneous hematomas of various localizations (anterior abdominal wall, retroperitoneal space, neck, hip, chest). The paper investigates the effectiveness of instrumental diagnostics – computed tomography in vascular mode is recognized as the optimal method, which helps to identify not only the location of the hematoma, but also in some cases its source. The basic principles of the tactics of choosing methods of hemostasis (medical, mechanical, surgical) to achieve its sustained effectiveness are described.
    Type of Medium: Online Resource
    ISSN: 2072-6732
    URL: Issue
    Language: Unknown
    Publisher: SPRIDA
    Publication Date: 2022
    detail.hit.zdb_id: 3041712-0
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  • 4
    In: Biomedical Photonics, Russian Photodynamic Association, Vol. 7, No. 4 ( 2019-01-14), p. 11-15
    Abstract: Cytological studies on lymph nodes of abdominal lymphodissection zone after local intraoperative photodynamic therapy (IOPDT) of gastrointestinal cancers were carried out. As a result of the PDT, the metastatic cells are destroyed, their cytoplasmic membranes and the cytoplasm disappears, leaving behind interphase nuclei ("naked nuclei") (p 〈 0,0001). Cytological confrmation of apoptosis (the presence of apoptotic bodies) in metastatic lymph nodes after IOPDT sessions on the lymph nodes of the abdominal lymphodissection zone is also presented.
    Type of Medium: Online Resource
    ISSN: 2413-9432
    URL: Issue
    Language: Unknown
    Publisher: Russian Photodynamic Association
    Publication Date: 2019
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  • 5
    Online Resource
    Online Resource
    SPRIDA ; 2022
    In:  Journal Infectology Vol. 14, No. 3 ( 2022-10-22), p. 50-54
    In: Journal Infectology, SPRIDA, Vol. 14, No. 3 ( 2022-10-22), p. 50-54
    Abstract: New coronavirus infection (COVID-19) is a modern global problem that requires the rapid development of diagnostic and treatment methods, as well as the study of pathological effects on body tissues. Due to severe damage to the respiratory organs, special attention is paid to the study of pneumothorax as a manifestation of gas syndrome, one of the complications of COVID-19. The purpose of the study was to assess the incidence of pneumothorax as a complication of COVID-19, the features of the development of the pathological process, and to determine the criteria for treatment tactics. Materials and methods . In total, for the period from April 2020 to May 2022 at the Clinical Infectious Diseases Hospital named after. S.P. Botkin treated 31532 patients with a confirmed diagnosis of COVID-19. As part of this study, the case histories of 316 patients with clinical manifestations of gas syndrome were retrospectively analyzed. All patients were diagnosed with COVID-19, the diagnostic criterion of which was a positive result of the PCR test – the detection of RNA in a swab taken from the nasopharynx and oropharynx. Results. Analysis of case histories showed that severe COVID-19 occurs in all age groups. Collapse of half of the lung was observed in most cases (59 patients). The main treatment method for pneumothorax was Bulau drainage. At the same time, in 47 patients (32%) this method required active aspiration. In 37 patients (26%), drainage was corrected and the pleural cavity was re-drained. In 37 patients, the result of hospitalization was a fatal outcome, the main causes of which were severe pneumonia and/or severe immunodeficiency, 75 patients (52%) were discharged from the hospital in a stable condition. Conclusions. The occurrence of pneumothorax in patients with COVID-19 is characterized by late onset, protracted course, the formation of purulent complications and a high incidence of fatal outcomes, which do not always correlate with the severity of pneumonia.
    Type of Medium: Online Resource
    ISSN: 2072-6732
    URL: Issue
    Language: Unknown
    Publisher: SPRIDA
    Publication Date: 2022
    detail.hit.zdb_id: 3041712-0
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