GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Online Resource
    Online Resource
    The Impact of Living Arrangements on the Prevalence of Falls after Total Joint Arthroplasty: A Comparison between Institutionalized and General Geriatric Population
    MDPI AG ; 2023
    In:  International Journal of Environmental Research and Public Health Vol. 20, No. 4 ( 2023-02-15), p. 3409-
    Details
    In: International Journal of Environmental Research and Public Health, MDPI AG, Vol. 20, No. 4 ( 2023-02-15), p. 3409-
    Abstract: Due to population aging, there is an increasing need for orthopedic surgery, especially total knee arthroplasty (TKA) and total hip arthroplasty (THA). In geriatric patients, postoperative falls are common events which can compromise the success of these expensive procedures. The aim of our study was to assess the influence of living arrangements on the prevalence of postoperative falls following joint replacement. We included 441 patients after TKA or THA, living in nursing homes, alone or with family. The prevalence of falls in the first 2 years (15.2%) was significantly influenced by living arrangements: patients with TKA or THA living alone had three times higher odds of falling compared to those living with family, and institutionalized patients with THA had four times higher odds of falling compared to those living with family. Of 67 patients who fell, 6 (8.9%) needed reintervention. For TKA patients, the fall rates were not significantly different between institutions and family, indicating the interest of nursing homes in offering proper care. However, for the THA group, the results were poorer, emphasizing the need for improvement in postoperative rehabilitation. Further multi-centric studies are required for generalizing the impact of living arrangements on fall prevalence after joint replacement.
    Type of Medium: Online Resource
    ISSN: 1660-4601
    URL: Article
    DOI: 10.3390/ijerph20043409
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2175195-X
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    In vivo Evaluation of a Collagen Scaffold Preconditioned with Adipose-derived Mesenchymal Stem Cells Used for Bone Regeneration A histological study
    Revista de Chimie SRL ; 2018
    In:  Materiale Plastice Vol. 55, No. 4 ( 2018-12-30), p. 691-695
    Details
    In: Materiale Plastice, Revista de Chimie SRL, Vol. 55, No. 4 ( 2018-12-30), p. 691-695
    Abstract: The use of collagen scaffolds and stem cells for obtaining a tissue-engineering complex has been an important concept in promoting repair and regeneration of the bone tissue. Such units represent important steps in the development of an ideal scaffold-cell complex that would sustain new bone apposition. The aim of our study was to perform a histologic evaluation of the healing of critical-sized bone defects, using a biologic collagen scaffold with adipose-derived mesenchymal stem cells, in comparison to negative controls created in the adjacent bone. We used 16 Wistar rats and according to the study design 2 calvarial bone defects were created in each animal, one was filled with collagen seeded with adipose-derived stem cells and the other one was considered negative control. During the following month, at weekly intervals, the animals were euthanized and the specimens from bone defects were histologically evaluated. The results showed that these scaffolds were highly biocompatible as only moderate inflammation no rejection reactions were observed. Furthermore, the first signs of osseous healing appeared after two weeks accompanied by angiogenesis. Collagen scaffolds seeded with adipose-derived mesenchymal stem cells can be considered a promising treatment option in bone regeneration of large defects.
    Type of Medium: Online Resource
    ISSN: 0025-5289 , 2668-8220
    URL: Article
    DOI: 10.37358/MP.18.4.5102
    Language: English
    Publisher: Revista de Chimie SRL
    Publication Date: 2018
    detail.hit.zdb_id: 2487166-7
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    Prevalence of the fabella and its association with pain in the posterolateral corner of the knee : A cross-sectional study in a Romanian population
    Ovid Technologies (Wolters Kluwer Health) ; 2018
    In:  Medicine Vol. 97, No. 47 ( 2018-11), p. e13333-
    Details
    In: Medicine, Ovid Technologies (Wolters Kluwer Health), Vol. 97, No. 47 ( 2018-11), p. e13333-
    Abstract: The functions and clinical consequences of the fabella, a sesamoid bone found in the posterolateral aspect of the knee joint, are still a reason of intense debate in the scientific literature. Its incidence was reported to range between 20% and 87% and its presence was usually associated with the persistent pain in the posterolateral region of the knee. The aim of our study was to measure the prevalence, anatomic and clinical features of the fabella within a cross-sectional study, conducted in a Romanian orthopaedic center. Between 2015 and 2017, a consecutive series of 562 patients with knee injuries or persistent knee pain has been examined by radiographs and Magnetic Resonance Imaging and a set of anatomical and clinical parameters have been recorded. Collected data was evaluated with RadiANT DICOM Viewer and statistically analyzed with GraphPad Prism 7. The level of significance was set at P   〈 .05. The incidence of the fabella in our study group was 16.93%, lower than previously reported for Caucasian populations. We found statistically significant differences regarding the possible association of the fabella with pain in the posterolateral corner of the knee ( P  = .04) and the 2 dimensions of the bone according to gender ( P  = .03 respectively P  = .01), but the prevalence was not influenced by gender ( P  = .6). The anatomic characteristics could be important in differentiating this sesamoid bone from calcifications or loose bodies located in the knee joint region. Due to the high association with the posterolateral knee pain, the fabella should be recorded during knee examination as a differential diagnosis, before any surgical procedure.
    Type of Medium: Online Resource
    ISSN: 0025-7974 , 1536-5964
    URL: Article
    DOI: 10.1097/MD.0000000000013333
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2018
    detail.hit.zdb_id: 2049818-4
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    Magnetic Resonance Imaging Assessment of Bone Regeneration in Osseous Defects Filled with Different Biomaterials. An experimental in vivo study
    Revista de Chimie SRL ; 2019
    In:  Materiale Plastice Vol. 56, No. 1 ( 2019-3-30), p. 235-238
    Details
    In: Materiale Plastice, Revista de Chimie SRL, Vol. 56, No. 1 ( 2019-3-30), p. 235-238
    Abstract: Noninvasive techniques, such as Magnetic Resonance Imaging (MRI) are becoming more used in the study of bone regeneration outcomes, in both animal models and human patients. Many studies have shown the potential of tissue engineering therapies to promote healing of skeletal injuries, but further research is needed to optimize these treatment options. This investigation is a continuation of other previous published studies, in which critical-sized bone defects created in the parietal bones of Wistar rats were filled with either bioglass or a biologic collagen scaffold seeded both with adipose-derived mesenchymal stem cells. The present study aims to present the applications of MRI in the assessment of the bone regeneration process in these previously created defects, at specific time intervals. MRI techniques are based on the differences between the spin-latice T1 and spin-spin T2 relaxation times of examined specimens or areas, compared to normal tissues. We measured the relaxation times specific to calvarial specimens with a Brukner Minispec. The results showed that the most favorable results were observed when a collagen scaffold seeded with stem cells was used. MRI enabled the detection of hard and even soft tissue changes, these findings suggesting that MRI could be an effective imaging modality for assessing changes in bone morphology and pathobiology. Furthermore, it can be used as an alternative to Computed Tomography in examining the role of various biomaterials used in bone healing, especially when ionizing radiation is contraindicated.
    Type of Medium: Online Resource
    ISSN: 0025-5289 , 2668-8220
    URL: Article
    DOI: 10.37358/MP.19.1.5158
    Language: English
    Publisher: Revista de Chimie SRL
    Publication Date: 2019
    detail.hit.zdb_id: 2487166-7
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 5
    Online Resource
    Online Resource
    Evaluation of Kangoo Jumps rebound exercise program: A prospective study of a general population
    Romanian Association of Balneology ; 2022
    In:  Balneo and PRM Research Journal Vol. 13, No. Vol.13, no.3 ( 2022-9-5), p. 511-
    Details
    In: Balneo and PRM Research Journal, Romanian Association of Balneology, Vol. 13, No. Vol.13, no.3 ( 2022-9-5), p. 511-
    Abstract: Introduction. The number of non-communicable diseases (NCDs) is in a constant rise, especially in the low and middle income countries. They could be highly prevented by implementing programs that will help in promoting health and changing harmful behaviors. The aim of this paper is to show that Rebound exercisesis a great example of such physical activity. Material and method. The study plan was designed to asses both physical and functional explorations, ultrasound scans, self-perception of body image and laboratory parameters for each patient. A total of 64 parameters were analyzed: 44 anthropometric parameters and 20 body composition parameters from 80 participants. The subjects were analyzed for a period of 6 months. Results and discussions. Parameters were analyzed at the beginning of the study (07.02.2019), after 3 months (25.05.2019) and at the end (26.09.2019). The results showed improvements in all utilized parameters. Conclusions. This study offers a novel perspective on Kangoo jumps practice. People with spine problems, diabetes, overweight levels, improved their health, got rid of back pain, lost weight and had a more toned body. Keywords: physical activity, overweight, harmful behaviors, non-communicable diseases
    Type of Medium: Online Resource
    ISSN: 2734-8458 , 2734-844X
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.12680/balneo.2022.13.3
    DOI: 10.12680/balneo.prm
    DOI: 10.12680/balneo.2022.511
    Language: English
    Publisher: Romanian Association of Balneology
    Publication Date: 2022
    detail.hit.zdb_id: 3059504-6
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 6
    Online Resource
    Online Resource
    Medical Students’ View on Troublesome Aspects of Bedside Manner in a Multilingual Area
    Elsevier BV ; 2014
    In:  Procedia - Social and Behavioral Sciences Vol. 142 ( 2014-08), p. 243-247
    Details
    In: Procedia - Social and Behavioral Sciences, Elsevier BV, Vol. 142 ( 2014-08), p. 243-247
    Type of Medium: Online Resource
    ISSN: 1877-0428
    URL: Article
    DOI: 10.1016/j.sbspro.2014.07.622
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2014
    detail.hit.zdb_id: 2488217-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 7
    Online Resource
    Online Resource
    Is Microfracture Alone Enough?
    MDPI AG ; 2021
    In:  Applied Sciences Vol. 11, No. 16 ( 2021-08-09), p. 7309-
    Details
    In: Applied Sciences, MDPI AG, Vol. 11, No. 16 ( 2021-08-09), p. 7309-
    Abstract: The technique of microfracture (MFX) was first performed 40 years ago and served for many years as the main procedure for repairing cartilage defects. There is a need to improve microfractures because the regenerated cartilage differs from the original histological aspect; it is less hyaline and more fibrocartilaginous. In addition, and more importantly, the benefits do not persist and the long-term results are unsatisfactory. Adjunctive treatments include platelet-rich plasma (PRP), cell-free-based scaffolds, adipose-derived mesenchymal stem cells (ADSCs), and bone marrow aspirate concentrate (BMAC). The aim of this review was to provide an overview and a perspective of the available data regarding MFX and the principal adjunctive treatments from recent years and also to challenge the traditional MFX procedure. We found that cell-free scaffolds, platelet-rich plasma, and bone marrow aspirate concentrate, although they are relatively novel therapies, showed great potential and maintained their clinical benefits for longer periods of time compared to microfracture alone. As for chitosan-based therapy and adipose-derived mesenchymal stem cells, we were not able to form a definitive conclusion. We believe that the available data show promising results, and future research should be done on each topic discussed. Moreover, investigators involved in bone marrow stimulation techniques should focus on conducting prospective comparative studies, performing second-look arthroscopy, and rely on a single enhancement procedure that can be adequately compared with MFX alone.
    Type of Medium: Online Resource
    ISSN: 2076-3417
    URL: Article
    DOI: 10.3390/app11167309
    Language: English
    Publisher: MDPI AG
    Publication Date: 2021
    detail.hit.zdb_id: 2704225-X
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 8
    Online Resource
    Online Resource
    Histopathological Evaluation and Expression of the Pluripotent Mesenchymal Stem Cell-Like Markers Cd105 and Cd44 in the Synovial Membrane of Patients with Primary versus Secondary Hip Osteoarthritis
    SAGE Publications ; 2017
    In:  Journal of Investigative Medicine Vol. 65, No. 2 ( 2017-02), p. 363-369
    Details
    In: Journal of Investigative Medicine, SAGE Publications, Vol. 65, No. 2 ( 2017-02), p. 363-369
    Abstract: To present the morphological changes of classic primary versus rapidly progressive and secondary hip osteoarthritis (HO) and to examine the expression of two pluripotent mesenchymal stem cell-like markers in the synovial membrane. A prospective observational study was conducted in 57 consecutive cases of radiologically confirmed HO in which total hip arthroplasty was performed. Based on the radiological and clinicopathological features, the cases were divided into three categories: classic primary HO (group A; n=16), rapidly destructive HO (group B; n=24), and HO secondary to avascular osteonecrosis of the femoral head (group C; n=17). Immunostains were performed using the markers CD44 and CD105. The cases from group A were mainly characterized by a marked perivascular inflammatory infiltrate and simple synovial hyperplasia. In group B, the papillary type of synovial hyperplasia was found and presence of chondromatosis, ossification, and ectopic follicles with germinal centers in the subsynovial layer was characteristic, whereas marked calcification and/or ossification were seen in group C. Focal expression of the CD105 and CD44 was noted in the hyperplastic synovial cells and subsynovial layer in cases from group A, whereas synovial cells from group B were diffusely positive for both CD44 and CD105. In secondary HO, CD44 marked the inflammatory cells. Mobilization of the CD44/CD105 positive synovial cells seems to play a role in the genesis of HO. The number of the pluripotent mesenchymal stem cell-like cells derived from the hyperplastic synovial cells might be related to the severity of possible immune-mediated rapidly destructive HO.
    Type of Medium: Online Resource
    ISSN: 1081-5589 , 1708-8267
    URL: Article
    DOI: 10.1136/jim-2016-000244
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 9
    Online Resource
    Online Resource
    Dynamics of Metabolic and Inflammatory Parameters in Overweight Patients Undergoing Knee or hip Arthroplasty
    Revista de Chimie SRL ; 2018
    In:  Revista de Chimie Vol. 69, No. 6 ( 2018-7-15), p. 1441-1446
    Details
    In: Revista de Chimie, Revista de Chimie SRL, Vol. 69, No. 6 ( 2018-7-15), p. 1441-1446
    Abstract: Osteoarthritis is a common problem in overweight and obese individuals and may lead to severe forms located especially at the knee and hip joints. Arthroplasty in these cases represents the appropriate treatment to solve the pain and to improve joint mobility. This intervention influences the laboratory parameters in different ways. The aim of the study was to compare pre- and postoperative values of metabolic and inflammatory parameters related to joint replacement surgery in patients suffering from advanced stages of knee and hip osteoarthritis, and to assess the relationship between different laboratory findings, taking into consideration the main cardio-metabolic comorbidities. The study was conducted at the Clinic of Orthopaedics and Traumatology of the Clinical County Hospital Mures between 2016-2017 on 57 overweight patients having severe knee or hip osteoarthritis undergoing total knee or hip arthroplasty. Plasma metabolic tests (uricemia, glycemia, triglycerides, cholesterol) and inflammatory markers (fibrinogen, high sensitive C-reactive protein - hsCRP) were followed in the studied overweight patients in the morning just before arthroplasty and 24 h after surgery. Dynamics of the measured laboratory tests and the relationship between them were assessed. Body mass index, waist circumference and cardio-metabolic associated diseases have also been evaluated. Significant decrease of uricemia, cholesterolemia, plasma triglyceride concentration and significant increase of hsCRP could be observed after joint replacement surgery compared to the previous values measured before the intervention. Glycemia was slightly higher after the arthroplasty, but the difference is not quite significant. Negative correlation could be found between preoperative HDL-cholesterol and plasma triglyceride level, while triglyceride concentration showed positive correlation with LDL-cholesterol and uricemia. BMI showed positive correlation with postoperative fibrinogen values. Hypertension was the most frequent cardio-metabolic comorbidity in the studied group. Significant difference occured in the level of a sensitive inflammatory marker and several biochemical laboratory tests suffered notable changes before and after arthroplasty in the studied group. Metabolic status was deeply affected by such an intervention during the first day after surgery. Laboratory components of the metabolic syndrome were present in close relationship in several patients. Further studies need to be performed for the dynamic assessment of more complex metabolic and inflammatory parameters in patients with similar pathology in order to evaluate the postoperative evolution and to provide appropriate support for these patients in the recovery process.
    Type of Medium: Online Resource
    ISSN: 0034-7752 , 2668-8212
    URL: Article
    DOI: 10.37358/RC.18.6.6342
    Language: English
    Publisher: Revista de Chimie SRL
    Publication Date: 2018
    detail.hit.zdb_id: 2488208-2
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 10
    Online Resource
    Online Resource
    S53P4 Bioactive Glass - an Alternative Treatment of Bone Defects
    Revista de Chimie SRL ; 2017
    In:  Revista de Chimie Vol. 68, No. 2 ( 2017-3-15), p. 387-389
    Details
    In: Revista de Chimie, Revista de Chimie SRL, Vol. 68, No. 2 ( 2017-3-15), p. 387-389
    Abstract: A challenging problem in orthopedic practice is represented by bone defects may they occur from trauma, malignancy, infection or congenital disease. Bioactive Glasses have a widely recognized ability to foster the growth of bone cells, and to bond strongly with both hard and soft tissues. Upon implantation, Bioactive Glasses undergoes specific reactions, leading to the formation of an amorphous calcium phosphate or crystalline hydroxyapatite phase on the surface of the glass, which is responsible for its strong bonding with the surrounding tissue. This phenomenon sustains a more rapid healing of bone defects and presents great antibacterial properties. In this paper we report on a clinical study that uses S53P4 Bioactive Glass to successfully treat bone defects and testify of the good compatibility of this material with human tissues.
    Type of Medium: Online Resource
    ISSN: 0034-7752 , 2668-8212
    URL: Article
    DOI: 10.37358/RC.17.2.5459
    Language: English
    Publisher: Revista de Chimie SRL
    Publication Date: 2017
    detail.hit.zdb_id: 2488208-2
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...