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  • 1
    Online Resource
    Online Resource
    The Relationship between Cerebral Small Vessel Disease, Hippocampal Volume and Cognitive Functioning in Patients with COPD: An MRI Study
    Frontiers Media SA ; 2017
    In:  Frontiers in Aging Neuroscience Vol. 9 ( 2017-03-30)
    Details
    In: Frontiers in Aging Neuroscience, Frontiers Media SA, Vol. 9 ( 2017-03-30)
    Type of Medium: Online Resource
    ISSN: 1663-4365
    URL: Article
    DOI: 10.3389/fnagi.2017.00088
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2017
    detail.hit.zdb_id: 2558898-9
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  • 2
    Online Resource
    Online Resource
    The COgnitive-Pulmonary Disease (COgnitive-PD) study: protocol of a longitudinal observational comparative study on neuropsychological functioning of patients with COPD
    BMJ ; 2014
    In:  BMJ Open Vol. 4, No. 3 ( 2014-03), p. e004495-
    Details
    In: BMJ Open, BMJ, Vol. 4, No. 3 ( 2014-03), p. e004495-
    Abstract: Intact cognitive functioning is necessary for patients with chronic obstructive pulmonary disease (COPD) to understand the value of healthy lifestyle guidelines, to make informed decisions and subsequently act on it. Nevertheless, brain abnormalities and cognitive impairment have been found in patients with COPD. To date, it remains unknown which cognitive domains are affected and what the possible consequences are of cognitive impairment. Therefore, objectives of the study described are to determine neuropsychological functioning in patients with COPD, and its influence on health status, daily functioning and pulmonary rehabilitation outcome. Furthermore, structural and functional brain abnormalities and the relationship with cognitive and daily functioning will be explored. Methods and analysis A longitudinal observational comparative study will be performed in 183 patients with COPD referred for pulmonary rehabilitation and in 90 healthy control participants. Demographic and clinical characteristics, activities of daily living and knowledge about COPD will be assessed. Baseline cognitive functioning will be compared between patients and controls using a detailed neuropsychological testing battery. An MRI substudy will be performed to compare brain abnormalities between 35 patients with COPD with cognitive impairment and 35 patients with COPD without cognitive impairment. Patients will be recruited between November 2013 and November 2015. Ethics and dissemination The study has been approved by the Medical Ethics Committee of the University Hospital Maastricht and Maastricht University (NL45127.068.13/METC 13-3-035) and is registered in the Dutch trial register. All participants will provide written informed consent and can withdraw from the study at any point in time. Assessment and home visit data material will be managed anonymously. The results obtained can be used to optimise patient-oriented treatment for cognitively impaired patients with COPD. The findings will be disseminated in international peer-reviewed journals and through research conferences.
    Type of Medium: Online Resource
    ISSN: 2044-6055 , 2044-6055
    URL: Article
    DOI: 10.1136/bmjopen-2013-004495
    Language: English
    Publisher: BMJ
    Publication Date: 2014
    detail.hit.zdb_id: 2599832-8
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  • 3
    Online Resource
    Online Resource
    Cognitive impairment and clinical characteristics in patients with chronic obstructive pulmonary disease
    SAGE Publications ; 2018
    In:  Chronic Respiratory Disease Vol. 15, No. 2 ( 2018-05), p. 91-102
    Details
    In: Chronic Respiratory Disease, SAGE Publications, Vol. 15, No. 2 ( 2018-05), p. 91-102
    Abstract: We aimed to investigate (1) the relationship between cognitive impairment (CI) and disease severity and (2) the potential differences in exercise performance, daily activities, health status, and psychological well-being between patients with and without CI. Clinically stable chronic obstructive pulmonary disease (COPD) patients, referred for pulmonary rehabilitation, underwent a neuropsychological examination. Functional exercise capacity (6-minute walk test [6MWT]), daily activities (Canadian Occupational Performance Measure [COPM] ), health status (COPD Assessment Test [CAT]) and St George’s Respiratory Questionnaire-COPD specific [SGRQ-C] ), and psychological well-being (Hospital Anxiety and Depression Scale [HADS], Beck Depression Inventory [BDI] , and Symptom Checklist 90 [SCL-90]) were compared between patients with and without CI. Of 183 COPD patients (mean age 63.6 (9.4) years, FEV 1 54.8 (23.0%) predicted), 76 (41.5%) patients had CI. The prevalence was comparable across Global Initiative for Chronic Obstructive Lung Disease (GOLD) grades 1–4 (44.8%, 40.0%, 41.0%, 43.5%, respectively, p = 0.97) and GOLD groups A–D (50.0%, 44.7%, 33.3%, 40.2%, respectively, p = 0.91). Patients with and without CI were comparable for demographics, smoking status, FEV 1 % predicted, mMRC, 6MWT, COPM, CAT, HADS, BDI, and SCL-90 scores. Clinical characteristics of COPD patients with and without CI are comparable. Assessment of CI in COPD, thus, requires an active case-finding approach.
    Type of Medium: Online Resource
    ISSN: 1479-9731 , 1479-9731
    URL: Article
    DOI: 10.1177/1479972317709651
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2222367-8
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  • 4
    Online Resource
    Online Resource
    Change in Sensory Functioning Predicts Change in Cognitive Functioning: Results from a 6‐Year Follow‐Up in the Maastricht Aging Study
    Wiley ; 2005
    In:  Journal of the American Geriatrics Society Vol. 53, No. 3 ( 2005-03), p. 374-380
    Details
    In: Journal of the American Geriatrics Society, Wiley, Vol. 53, No. 3 ( 2005-03), p. 374-380
    Abstract: Objectives: To examine the longitudinal relationship between sensory functioning and a broad range of cognitive functions after 6 years follow‐up and whether cataract surgery or first‐time hearing aid use affected cognition. Design: Hierarchical regression procedures were employed to determine whether sensory functioning was predictive of cognitive performance. Setting: Maastricht University and the University Hospital Maastricht, the Netherlands. Participants: Older Dutch adults (≥55) enrolled in the Maastricht Aging Study (N=418). Measurements: Visual and auditory acuity, the Visual Verbal Learning Test (VVLT), the Stroop Color Word Test (SCWT), the Concept Shifting Task (CST), the Verbal Fluency Test, and the Letter‐Digit Substitution Test (LDST). Results: A change in visual acuity was associated with change in most cognitive measures, including the total and recall scores of the VVLT, the mean score of the first two SCWT cards, the mean score of the first two CST cards and the LDST. In addition, a change in auditory acuity predicted change in memory performance (VVLT total and recall scores), and auditory acuity measured at baseline predicted change in the mean score of the first two SCWT cards and the LDST. Conclusion: The findings support the notion of a strong connection between sensory acuity in auditory and visual domains and cognitive performance measures, both from a cross‐sectional and a longitudinal perspective. They also suggest that it is essential to screen older individuals in a clinical context for sensory functioning so that changes in visual or auditory acuity are not interpreted as changes in cognitive performance.
    Type of Medium: Online Resource
    ISSN: 0002-8614 , 1532-5415
    URL: Issue
    URL: Article
    DOI: 10.1111/jgs.2005.53.issue-3
    DOI: 10.1111/j.1532-5415.2005.53152.x
    Language: English
    Publisher: Wiley
    Publication Date: 2005
    detail.hit.zdb_id: 2040494-3
    detail.hit.zdb_id: 80363-7
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  • 5
    Online Resource
    Online Resource
    Validity of the Groningen Effort Test in patients with suspected chronic solvent-induced encephalopathy
    Oxford University Press (OUP) ; 2024
    In:  Archives of Clinical Neuropsychology ( 2024-04-03)
    Details
    In: Archives of Clinical Neuropsychology, Oxford University Press (OUP), ( 2024-04-03)
    Abstract: The use of performance validity tests (PVTs) in a neuropsychological assessment to determine indications of invalid performance has been a common practice for over a decade. Most PVTs are memory-based; therefore, the Groningen Effort Test (GET), a non-memory-based PVT, has been developed. Objectives This study aimed to validate the GET in patients with suspected chronic solvent-induced encephalopathy (CSE) using the criterion standard of 2PVTs. A second goal was to determine diagnostic accuracy for GET. Method Sixty patients with suspected CSE referred for NPA were included. The GET was compared to the criterion standard of 2PVTs based on the Test of Memory Malingering and the Amsterdam Short Term Memory Test. Results The frequency of invalid performance using the GET was significantly higher compared to the criterion of 2PVTs (51.7% vs. 20.0% respectively; p  & lt; 0.001). For the GET index, the sensitivity was 75% and the specificity was 54%, with a Youden’s Index of 27. Conclusion The GET showed significantly more invalid performance compared to the 2PVTs criterion suggesting a high number of false positives. The general accepted minimum norm of specificity for PVTs of & gt;90% was not met. Therefore, the GET is of limited use in clinical practice with suspected CSE patients.
    Type of Medium: Online Resource
    ISSN: 1873-5843
    URL: Article
    DOI: 10.1093/arclin/acae025
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2024
    detail.hit.zdb_id: 2003528-7
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  • 6
    Online Resource
    Online Resource
    Training Memory Self-efficacy in the Chronic Stage After Stroke : A Randomized Controlled Trial
    SAGE Publications ; 2013
    In:  Neurorehabilitation and Neural Repair Vol. 27, No. 2 ( 2013-02), p. 110-117
    Details
    In: Neurorehabilitation and Neural Repair, SAGE Publications, Vol. 27, No. 2 ( 2013-02), p. 110-117
    Abstract: Background. Stroke patients with a low memory self-efficacy (MSE) report more memory complaints than patients with a high MSE. Objective. The aim of this study was to examine the effect of a memory-training program on MSE in the chronic phase after stroke and to identify which patients benefit most from the MSE training program. Methods. In a randomized controlled trial, the effectiveness of the MSE training program (experimental group) was compared with a peer support program (control group) in chronic stroke patients. The primary outcome was MSE, measured using the Metamemory-In-Adulthood Questionnaire. Secondary outcomes included depression, quality of life, and objective verbal memory capacity. Changes in outcomes over the intervention period were compared between both groups. Demographic and clinical variables were studied as potential predictors of MSE outcome in the experimental group. Results. In total, 153 patients were included: mean age = 58 years (standard deviation [SD] = 9.7), 54.9% male, and mean of 54 months (SD = 37) after stroke. Of these, 77 were assigned to the training and 76 to the control group. Improvement of MSE ( B = 0.40; P = .019) was significantly greater in the training than in the control group. No significant differences were found for the secondary outcomes. An increase in MSE after training was predicted by a younger age ( B = −0.033; P = .006) and a better memory capacity ( B = 0.043; P = .009), adjusted for baseline MSE. Conclusions. MSE can be improved by the MSE training program for stroke patients. Younger patients and patients with a better memory capacity benefit most from the MSE training program (Dutch Trial Register: NTR-TC 1656).
    Type of Medium: Online Resource
    ISSN: 1545-9683 , 1552-6844
    URL: Article
    DOI: 10.1177/1545968312455222
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2013
    detail.hit.zdb_id: 2100545-X
    detail.hit.zdb_id: 1491637-X
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  • 7
    Online Resource
    Online Resource
    COgnitive-Pulmonary Disease
    Wiley ; 2014
    In:  BioMed Research International Vol. 2014 ( 2014), p. 1-8
    Details
    In: BioMed Research International, Wiley, Vol. 2014 ( 2014), p. 1-8
    Abstract: Over the past few decades, chronic obstructive lung disease (COPD) has been considered a disease of the lungs, often caused by smoking. Nowadays, COPD is regarded as a systemic disease. Both physical effects and effects on brains, including impaired psychological and cognitive functioning, have been demonstrated. Patients with COPD may have cognitive impairment, either globally or in single cognitive domains, such as information processing, attention and concentration, memory, executive functioning, and self-control. Possible causes are hypoxemia, hypercapnia, exacerbations, and decreased physical activity. Cognitive impairment in these patients may be related to structural brain abnormalities, such as gray-matter pathologic changes and the loss of white matter integrity which can be induced by smoking. Cognitive impairment can have a negative impact on health and daily life and may be associated with widespread consequences for disease management programs. It is important to assess cognitive functioning in patients with COPD in order to optimize patient-oriented treatment and to reduce personal discomfort, hospital admissions, and mortality. This paper will summarize the current knowledge about cognitive impairment as extrapulmonary feature of COPD. Hereby, the impact of smoking on cognitive functioning and the impact of cognitive impairment on smoking behaviour will be examined.
    Type of Medium: Online Resource
    ISSN: 2314-6133 , 2314-6141
    URL: Article
    DOI: 10.1155/2014/697825
    Language: English
    Publisher: Wiley
    Publication Date: 2014
    detail.hit.zdb_id: 2698540-8
    detail.hit.zdb_id: 2705584-X
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  • 8
    Online Resource
    Online Resource
    Influence of cognitive functioning on functional status in an older population: 3‐ and 6‐year follow‐up of the Maastricht Aging Study
    Wiley ; 2005
    In:  International Journal of Geriatric Psychiatry Vol. 20, No. 9 ( 2005-09), p. 883-888
    Details
    In: International Journal of Geriatric Psychiatry, Wiley, Vol. 20, No. 9 ( 2005-09), p. 883-888
    Abstract: To date, it remains unclear to what extent cognitive competence is related to a change in general functional status in older adults. Objectives To evaluate both the cross‐sectional and the longitudinal relation between cognitive functioning and functional status. Methods Sensorimotor speed, memory, and executive functioning were assessed in a large population of healthy adults aged 60 years and older (n = 485) who participated in the Maastricht Aging Study. Data from the baseline (1993–1995), three‐year follow‐up, and six‐year follow‐up were used. Functional status was measured using the SF‐36, which was coded into a physical and a mental component summary measure. Results After adjustment for age, sex, and educational level, a high level of cognitive functioning appeared to be associated with better functional status in the cross‐sectional analysis. Longitudinal analyses demonstrated, that cognitive functioning was not a predictor of functional status three or six years later. Conclusions Thus while cognitive functioning is useful clinically for predicting the short‐term functional status of an older person, it is not useful for predicting that person's long‐term ( 〉 3 years) functional status and thus the period of validity of the results of these tests in answering such questions is limited. Copyright © 2005 John Wiley & Sons, Ltd.
    Type of Medium: Online Resource
    ISSN: 0885-6230 , 1099-1166
    URL: Issue
    URL: Article
    DOI: 10.1002/gps.v20:9
    DOI: 10.1002/gps.1373
    RVK:
    XA 10000
    Language: English
    Publisher: Wiley
    Publication Date: 2005
    detail.hit.zdb_id: 806736-3
    detail.hit.zdb_id: 1500455-7
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  • 9
    Online Resource
    Online Resource
    Long-Lasting Effects of a New Memory Self-efficacy Training for Stroke Patients : A Randomized Controlled Trial
    SAGE Publications ; 2014
    In:  Neurorehabilitation and Neural Repair Vol. 28, No. 3 ( 2014-03), p. 199-206
    Details
    In: Neurorehabilitation and Neural Repair, SAGE Publications, Vol. 28, No. 3 ( 2014-03), p. 199-206
    Abstract: Background and purpose. This study aims to determine the long-term effects of a new Memory Self-efficacy (MSE) training program for stroke patients on MSE, depression, and quality of life. Methods. In a randomized controlled trial, patients were allocated to a MSE training or a peer support group. Outcome measures were MSE, depression, and quality of life, measured with the Metamemory-In-Adulthood questionnaire, Center for Epidemiological Studies–Depression Scale (CES-D), and the Who-Qol Bref questionnaire, respectively. We used linear mixed models to compare the outcomes of both groups immediately after training, after 6 months, and after 12 months, adjusted for baseline. Results. In total, 153 former inpatients from 2 rehabilitation centers were randomized—77 to the experimental and 76 to the control group. MSE increased significantly more in the experimental group and remained significantly higher than in the control group after 6 and 12 months (B = 0.42; P = .010). Psychological quality of life also increased more in the experimental group but not significantly (B = 0.09; P = .077). However, in the younger subgroup of patients ( 〈 65 years old), psychological quality of life significantly improved in the experimental group compared to the control group and remained significantly higher over time (B = 0.14; P = .030). Other outcome measures were not significantly different between both groups. Conclusions. An MSE training program improved MSE and psychological quality of life in stroke patients aged 〈 65 years. These effects persisted during 12 months of follow-up.
    Type of Medium: Online Resource
    ISSN: 1545-9683 , 1552-6844
    URL: Article
    DOI: 10.1177/1545968313478487
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2100545-X
    detail.hit.zdb_id: 1491637-X
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  • 10
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    Adherence to driving cessation advice given to patients with cognitive impairment and consequences for mobility
    Springer Science and Business Media LLC ; 2018
    In:  BMC Geriatrics Vol. 18, No. 1 ( 2018-12)
    Details
    In: BMC Geriatrics, Springer Science and Business Media LLC, Vol. 18, No. 1 ( 2018-12)
    Type of Medium: Online Resource
    ISSN: 1471-2318
    URL: Article
    DOI: 10.1186/s12877-018-0910-4
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2018
    detail.hit.zdb_id: 2059865-8
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