In:
Urologia Internationalis, S. Karger AG, Vol. 86, No. 3 ( 2011), p. 284-289
Abstract:
〈 i 〉 Introduction: 〈 /i 〉 The study aimed to evaluate the long-term efficacy of treatment with extract of 〈 i 〉 Serenoa repens 〈 /i 〉 (Prostamol Uno) in patients with lower urinary tract symptoms (LUTS) induced by benign prostatic hyperplasia (BPH). 〈 i 〉 Patients and Methods: 〈 /i 〉 We studied 120 patients with mild or moderate LUTS induced by BPH, maximal urinary flow (Q 〈 sub 〉 max 〈 /sub 〉 ) 〈 15 ml with a voided volume ≧150 ml, prostate-specific antigen 〈 4 ng/ml, and residual urinary volume 〈 150 ml, treated daily for 24 months with one capsule of 320 mg ethanolic extract of 〈 i 〉 Serenoa repens 〈 /i 〉 . 〈 i 〉 Results: 〈 /i 〉 Statistically significant improvements in the International Prostate Symptom Score (5.5 points), quality of life (QoL; 1.8 points), Q 〈 sub 〉 max 〈 /sub 〉 (5.6 ml/s), International Index of Erectile Function (IIEF; 6.4 points) and reduction in residual urinary volume were observed during the study period. The mean prostate volume at 24 months was 36 ml, compared to 39.8 ml at baseline. 〈 i 〉 Conclusions: 〈 /i 〉 Long-term treatment with 320 mg ethanolic extract of 〈 i 〉 Serenoa repens 〈 /i 〉 proved to be efficient in reducing urinary obstruction, improving symptomatology and QoL of BPH patients. It also had a positive effect on sexual function, demonstrated by the statistically significant increase in the IIEF.
Type of Medium:
Online Resource
ISSN:
0042-1138
,
1423-0399
Language:
English
Publisher:
S. Karger AG
Publication Date:
2011
detail.hit.zdb_id:
1464417-4
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