In:
The International Journal of Cardiovascular Imaging, Springer Science and Business Media LLC, Vol. 36, No. 10 ( 2020-10), p. 2051-2059
Abstract:
To compare intravenous contrast material (CM) injection protocols for dual-energy CT pulmonary angiography (CTPA) in patients with suspected acute pulmonary embolism with regard to image quality and pulmonary perfused blood volume (PBV) values. A total of 198 studies performed with four CM injection protocols varying in CM volume and iodine delivery rates (IDR) were retrospectively included: (A) 60 ml at 5 ml/s (IDR = 1.75gI/s), (B) 50 ml at 5 ml/s (IDR = 1.75gI/s), (C) 50 ml at 4 ml/s (IDR = 1.40gI/s), (D) 40 ml at 3 ml/s (IDR = 1.05gI/s). Image quality and PBV values at different resolution settings were compared. Pulmonary arterial tract attenuation was highest for protocol A (397 ± 110 HU; p vs. B = 0.13; vs. C = 0.02; vs. D 〈 0.001). CTPA image quality of protocol A was rated superior compared to protocols B and D by reader 1 ( p = 0.01; 〈 0.001), and superior to protocols B, C and D by reader 2 ( p 〈 0.001; 0.02; 〈 0.001). Otherwise, there were no significant differences in CTPA quality ratings. Subjective iodine map ratings did not vary significantly between protocols A, B, and C. Both readers rated protocol D inferior to all other protocols ( p 〈 0.05). PBV values did not vary significantly between protocols A and B at resolution settings of 1, 4 and 10 ( p = 0.10; 0.10; 0.09), while otherwise PBV values displayed a decreasing trend from protocol A to D ( p 〈 0.05). Higher CM volume and IDR are associated with superior CTPA and iodine map quality and higher absolute PBV values.
Type of Medium:
Online Resource
ISSN:
1569-5794
,
1573-0743
DOI:
10.1007/s10554-020-01911-8
Language:
English
Publisher:
Springer Science and Business Media LLC
Publication Date:
2020
detail.hit.zdb_id:
3163889-2
detail.hit.zdb_id:
2055311-0
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