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  • 1
    In: Journal of Alloys and Compounds, Elsevier BV, Vol. 890 ( 2022-01), p. 161909-
    Type of Medium: Online Resource
    ISSN: 0925-8388
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2022
    detail.hit.zdb_id: 2012675-X
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  • 2
    In: Geofluids, Hindawi Limited, Vol. 2022 ( 2022-3-11), p. 1-14
    Abstract: CO2 and hydrocarbon fluids typically migrate from deeper layers into the shallow crust via large deep faults. Consequently, CO2, hydrocarbon, and water reservoirs tend to occur in traps near deep and large faults. In this study, we use structural and stratigraphic data to identify and predict CO2 and hydrocarbon gas reservoirs near major deep faults. In order to investigate how CO2 accumulates in the major deep faults of the Ying-Qiong Basin (YQB), we quantify the carbon footprint of this area by analyzing the No. 1 fault, the No. 2 fault, and the adjacent gas reservoirs. Using 3D seismic data and geochemical data, we determine how the fault structure affects the ambient CO2 enrichment on a given fault. Our results indicate that the LD10 and BD19 gas reservoirs have high inorganic CO2 contents, while the HK29 gas reservoir has a low organic CO2 content. Based on our analyses, we conclude that the gas source, fault activity, and fault structure control the CO2 accumulation in subsurface layers. While mantle-derived volcanic inorganic CO2 disperses upward along the main fault when a given fault is independent (i.e., it lacks secondary faults), the absence of additional vertical migration channels largely prevents the CO2 from travelling upward through thick mudstone cap rocks and collecting in shallow traps. These shallow traps are typically filled by shallow organic CO2 sources. However, parallel forward fault-step structures, such as secondary faults, can transport gas that is produced at deeper sources (such as CO2 generated by basement limestone) to shallower depths. If the hanging wall of a deep fault has many branching secondary faults, then these intersecting faults act as conduits that enable mantle-derived CO2 to travel vertically into shallow layers.
    Type of Medium: Online Resource
    ISSN: 1468-8123 , 1468-8115
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2045012-6
    SSG: 13
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  • 3
    In: Energies, MDPI AG, Vol. 14, No. 3 ( 2021-01-20), p. 533-
    Abstract: Miscible and near-miscible flooding are used to improve the performance of carbon-dioxide-enhanced oil recovery in heterogeneous porous media. However, knowledge of the effects of heterogeneous pore structure on CO2/oil flow behavior under these two flooding conditions is insufficient. In this study, we construct pore-scale CO2/oil flooding models for various flooding methods and comparatively analyze CO2/oil flow behavior and oil recovery efficiency in heterogeneous porous media. The simulation results indicate that compared to immiscible flooding, near-miscible flooding can increase the CO2 sweep area to some extent, but it is still inefficient to displace oil in small pore throats. For miscible flooding, although CO2 still preferentially displaces oil through big throats, it may subsequently invade small pore throats. In order to substantially increase oil recovery efficiency, miscible flooding is the priority choice; however, the increase of CO2 diffusivity has little effect on oil recovery enhancement. For immiscible and near-miscible flooding, CO2 injection velocity needs to be optimized. High CO2 injection velocity can speed up the oil recovery process while maintaining equivalent oil recovery efficiency for immiscible flooding, and low CO2 injection velocity may be beneficial to further enhancing oil recovery efficiency under near-miscible conditions.
    Type of Medium: Online Resource
    ISSN: 1996-1073
    Language: English
    Publisher: MDPI AG
    Publication Date: 2021
    detail.hit.zdb_id: 2437446-5
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  • 4
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2018
    In:  KSCE Journal of Civil Engineering Vol. 22, No. 9 ( 2018-9), p. 3491-3503
    In: KSCE Journal of Civil Engineering, Springer Science and Business Media LLC, Vol. 22, No. 9 ( 2018-9), p. 3491-3503
    Type of Medium: Online Resource
    ISSN: 1226-7988 , 1976-3808
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2018
    detail.hit.zdb_id: 2446036-9
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  • 5
    Online Resource
    Online Resource
    Wiley ; 2014
    In:  Journal of Applied Clinical Medical Physics Vol. 15, No. 4 ( 2014-07), p. 105-116
    In: Journal of Applied Clinical Medical Physics, Wiley, Vol. 15, No. 4 ( 2014-07), p. 105-116
    Abstract: Two patients with multiple lung metastases (≥ 5) were treated using frameless stereotactic body radiation therapy (SBRT) on an Elekta Axesse linear accelerator equipped with an interdigitation‐capable multileaf collimator and four‐dimensional cone‐beam CT (4D CBCT). The technique and the early clinical outcomes were evaluated. Patient A with five lung metastases and Patient B with seven lung metastases underwent SBRT (48 Gy/8 fractions for Patient A, 42 Gy/7 fractions for Patient B). The treatments were administered using a 6 MV photon beam. The nominal dose rate was 660 MUs/min. Patients were positioned and immobilized using thermoplastic masks and image guidance was done using 4D CBCT. The targets were delineated on the images of the 4D CT, and the positron emission tomography‐computed tomography (PET‐CT) images were taken as references. A two‐step, volumetric‐modulated arc therapy (VMAT) plan was designed for each patient. Step 1: the lesions in one lung were irradiated by a 210° arc field; Step 2: the rest of the lesions in the other lung were irradiated by a 120° arc field. Plans were evaluated using conformity index (CI) and homogeneity index (HI). Patients were followed up and adverse events were graded according to the Common Terminology Criteria for Adverse Events v4.0 (CTCAE v4.0). The beam‐on time of each treatment was less than 10 min. The CI and HI for the two plans were 0.562, 0.0709 and 0.513, 0.0794, respectively. Pulmonary function deteriorated slightly in both patients, and the patient with seven lung lesions was confirmed to have Grade 1 radiation pneumonitis. The technique was fast, accurate, and well tolerated by patients, and the two‐step plan is a helpful design in reducing the dose to the lungs. PACS numbers: 87.55‐x, 87.56.J‐, 87.56.‐v, 87.56.nk, 87.57.qp
    Type of Medium: Online Resource
    ISSN: 1526-9914 , 1526-9914
    Language: English
    Publisher: Wiley
    Publication Date: 2014
    detail.hit.zdb_id: 2010347-5
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  • 6
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2017
    In:  Scientific Reports Vol. 7, No. 1 ( 2017-06-13)
    In: Scientific Reports, Springer Science and Business Media LLC, Vol. 7, No. 1 ( 2017-06-13)
    Abstract: Irradiation on hippocampus would lead to neuro-cognitive dysfunction in locally advanced nasopharyneal carcinoma (LA-NPC) patients accepting radiotherapy. Our study here aimed to investigate if undergoing hippocampus sparing (HS) volume modulated arc therapy (VMAT) would influence the plan quality in LA NPC patients. We designed three kinds of radiotherapeutic plans for 11 LA NPC patients: conventional VMAT (C-VMAT), HS-VMAT and HS intensity modulated radiation therapy with dynamic multileaf collimator (HS-dMLC). And the dose distribution on targets and surrounding organs at risk (OAR) were carefully evaluated. We found out that the expected doses on hippocampus were significantly lowered in HS-VMAT (899 ± 378 cGy) and HS-dMLC (896 ± 321 cGy) as compared to C-VMAT (1518 ± 337 cGy, p  〈  0.05), but meaningless difference was presented on plan quality of targets (p  〉  0.05). Moreover, lower radiation doses on brain stem were observed in HS-VMAT plan in comparison with C-VMAT plan (p  〈  0.05). However, there were no statistically meaningful diversities in the doses received by other OARs among all plans. Here we concluded that HS-VMAT presented promising advantages on protecting hipppcampus and brain stem as compared to C-VMAT and HS-dMLC, but enthusiastically had no effects on plan quality in LA-NPC patients.
    Type of Medium: Online Resource
    ISSN: 2045-2322
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2017
    detail.hit.zdb_id: 2615211-3
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  • 7
    Online Resource
    Online Resource
    Forum Multimedia Publishing LLC ; 2020
    In:  The Heart Surgery Forum Vol. 23, No. 6 ( 2020-11-23), p. E870-E872
    In: The Heart Surgery Forum, Forum Multimedia Publishing LLC, Vol. 23, No. 6 ( 2020-11-23), p. E870-E872
    Abstract: Background: Idiopathic hyper eosinophilic syndrome (HES) is a rare disease characterized by a sustained increase in eosinophilia. Heart involvement is called Loffler endocarditis. Loffler endocarditis is a serious complication of hyper eosinophilia syndrome, which is characterized by a special type of fibrotic endocarditis. Loffler endocarditis is an inflammatory cardiac condition characterized by eosinophilic infiltration in the heart. The overall prognosis for patients with Loffler endocarditis is very poor. Methods: In this article we report an 8-year-old girl who was diagnosed as having Loffler endocarditis in thrombotic phase and was successfully treated with surgery. Results: Our patient had a good prognosis during the half-year follow-up. She had no symptoms of heart failure and echocardiography findings were normal. Conclusion: The cardiac damage occurred in a three-stage process: the necrotic, thrombotic, and fibrotic stages. This unusual but sometimes life-threatening disease is often detected in the late phase, resulting in no curative strategy available to reverse the disease process. The overall prognosis of patients with Loffler endocarditis is very poor. Current treatments include anticoagulation and anti-eosinophils therapy, and surgery only in selected cases. Surgical treatment of HES in adolescents is very rare. The present case illustrates that with well-controlled peripheral eosinophilia, proper surgical treatment in selected patients can improve their prognosis in the near future but long-term follow-up is necessary.
    Type of Medium: Online Resource
    ISSN: 1522-6662 , 1098-3511
    Language: Unknown
    Publisher: Forum Multimedia Publishing LLC
    Publication Date: 2020
    detail.hit.zdb_id: 2069230-4
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  • 8
    Online Resource
    Online Resource
    Frontiers Media SA ; 2024
    In:  Frontiers in Bioengineering and Biotechnology Vol. 12 ( 2024-3-27)
    In: Frontiers in Bioengineering and Biotechnology, Frontiers Media SA, Vol. 12 ( 2024-3-27)
    Abstract: Fragility fractures, which are more prevalent in women, may be significantly influenced by autophagy due to altered bone turnover. As an essential mediator of autophagy, Beclin-1 modulates bone homeostasis by regulating osteoclast and chondrocyte differentiation, however, the alteration in the local bone mechanical environment in female Beclin-1 +/− mice remains unclear. In this study, our aim is to investigate the biomechanical behavior of femurs from seven-month-old female wild-type (WT) and Beclin-1 +/− mice under peak physiological load, using finite element analysis on micro-CT images. Micro-CT imaging analyses revealed femoral cortical thickening in Beclin-1 +/− female mice compared to WT. Three-point bending test demonstrated a 63.94% increase in whole-bone strength and a 61.18% increase in stiffness for female Beclin-1 +/− murine femurs, indicating improved biomechanical integrity. After conducting finite element analysis, Beclin-1 +/− mice exhibited a 26.99% reduction in von Mises stress and a 31.62% reduction in maximum principal strain in the femoral midshaft, as well as a 36.64% decrease of von Mises stress in the distal femurs, compared to WT mice. Subsequently, the strength-safety factor was determined using an empirical formula, revealing that Beclin-1 +/− mice exhibited significantly higher minimum safety factors in both the midshaft and distal regions compared to WT mice. In summary, considering the increased response of bone adaptation to mechanical loading in female Beclin-1 +/− mice, our findings indicate that increasing cortical bone thickness significantly improves bone biomechanical behavior by effectively reducing stress and strain within the femoral shaft.
    Type of Medium: Online Resource
    ISSN: 2296-4185
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2024
    detail.hit.zdb_id: 2719493-0
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  • 9
    Online Resource
    Online Resource
    Informa UK Limited ; 2021
    In:  Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Vol. Volume 14 ( 2021-12), p. 4903-4909
    In: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Informa UK Limited, Vol. Volume 14 ( 2021-12), p. 4903-4909
    Type of Medium: Online Resource
    ISSN: 1178-7007
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2021
    detail.hit.zdb_id: 2494854-8
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  • 10
    In: Applied Materials Today, Elsevier BV, Vol. 3 ( 2016-06), p. 57-62
    Type of Medium: Online Resource
    ISSN: 2352-9407
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2016
    detail.hit.zdb_id: 2833442-5
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