In:
Acta Chimica Slovenica, Slovenian Chemical Society, Vol. 71, No. 1 ( 2024-3-20), p. 66-83
Abstract:
Detection of sialic acid using advanced sensors in milk-based products is essential in the food industry. Therefore, the present work reports the sulfur and nitrogen-doped graphene quantum dots from bone meal functionalized with boronic acid (Boro-S/N-dGQDs) nanoprobe for sialic acid sensing applications. Briefly, S/N-dGQDs were functionalized with 4-carboxyphenylboronic acid to improve performance of fluorescent sensors toward the detection of sialic acid. Here, boronic acid surface decoration on S/N-dGQD was confirmed by several spectral characterizations. The addition of different quantities of sialic acid results in a directly proportionate correlation to fluorescence quenching. It gives a broad linear range of 50 ng/mL to 1000 ng/mL and a limit of detection of 6.04 ng/mL. Also, it displayed remarkable selectivity, likely due to interaction of sialic acid-containing 1,2-diol with hydroxyl group of Boro-S/N-dGQDs nanoprobe. Designed sensor demonstrated good stability and reproducibility. Real-time analysis of sialic acid in different milk-based products confirmed practicability of Boro-S/N-dGQDs.
Type of Medium:
Online Resource
ISSN:
1580-3155
DOI:
10.17344/acsi.2023.8436
Language:
Unknown
Publisher:
Slovenian Chemical Society
Publication Date:
2024
detail.hit.zdb_id:
2029709-9
Permalink