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  • 1
    Online Resource
    Online Resource
    The Effect of Avastin on Posterior Capsular Opacification after Phacoemulsification: A Randomized Controlled Trial Mitsugu
    OMICS Publishing Group ; 2018
    In:  Journal of Clinical Trials Vol. 08, No. 03 ( 2018)
    Details
    In: Journal of Clinical Trials, OMICS Publishing Group, Vol. 08, No. 03 ( 2018)
    Type of Medium: Online Resource
    ISSN: 2167-0870
    URL: Journal
    URL: Article
    DOI: 10.4172/2167-0870
    DOI: 10.4172/2167-0870.1000350
    Language: Unknown
    Publisher: OMICS Publishing Group
    Publication Date: 2018
    detail.hit.zdb_id: 3115651-4
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  • 2
    Online Resource
    Online Resource
    Severe complications of tramadol overdose in Iran
    Korean Society of Epidemiology ; 2019
    In:  Epidemiology and Health Vol. 41 ( 2019-06-16), p. e2019026-
    Details
    In: Epidemiology and Health, Korean Society of Epidemiology, Vol. 41 ( 2019-06-16), p. e2019026-
    Abstract: OBJECTIVES: Severe complications of tramadol overdose have been reported; however, few large-scale studies have investigated this issue. Therefore, this study aimed to explore the presentation and complications of tramadol overdose in patients admitted to an intoxication referral center in northwestern Iran.METHODS: Patients with tramadol overdose admitted to Sina Teaching Hospital in Tabriz, Iran during 2013-2017 were included. For each patient, the following data were collected: demographics, previous drug or medication overdose, whether the patient was in the process of quitting drug use, ingested dose of tramadol and co-ingestants, Glasgow Coma Scale (GCS) score, clinical symptoms at the time of admission, and admission characteristics. Serotonin toxicity was diagnosed in patients who fit the Hunter criteria. Multiple logistic regression was performed to identify variables associated with the incidence of severe complications of tramadol overdose.RESULTS: In total, 512 cases of tramadol overdose were evaluated, of which 359 patients were included, with a median age of 41 years (range, 16-69) and a median tramadol dose of 1,500 mg (range, 500-4,000). The most frequent complications associated with tramadol overdose were hypertension (38.4%), tachycardia (24.8%), and seizure (14.5%). No serotonin toxicity was detected in patients. Having a GCS score 〈 15, having taken a tramadol dose of 〉 1,000 mg, being in the process of quitting drug use, being 30-49 years old, and male sex were significantly related to the incidence of severe complications of tramadol overdose.CONCLUSIONS: Although seizure was prevalent among Iranian patients with tramadol poisoning, serotonin toxicity and cardiogenic shock were rare findings.
    Type of Medium: Online Resource
    ISSN: 2092-7193
    URL: Article
    DOI: 10.4178/epih.e2019026
    Language: English
    Publisher: Korean Society of Epidemiology
    Publication Date: 2019
    detail.hit.zdb_id: 2590698-7
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  • 3
    Online Resource
    Online Resource
    Agreement between Impression of Stroke in the Emergency Department and Diagnosis at the Neurology Department
    Australian International Academic Centre ; 2019
    In:  Advances in Bioscience and Clinical Medicine Vol. 7, No. 3 ( 2019-07-31), p. 7-
    Details
    In: Advances in Bioscience and Clinical Medicine, Australian International Academic Centre, Vol. 7, No. 3 ( 2019-07-31), p. 7-
    Abstract: Background: Missing to detect an ischemic stroke in the emergency department leads to miss acute interventions and treatment with secondary prevention therapy. Our study examined the diagnosis of stroke in the emergency department (ED) and neurology department of an academic teaching hospital. Methods and Materials: A retrospective chart review was performed from March 2017 to March 2018. ED medical document (chart) were reviewed by a stroke neurologist to collect the clinical diagnosis and characteristics of ischemic stroke patients. For determining the cases of misdiagnosed and over diagnosed data, the administrative data codes were compared with the chart adjudicated diagnosis. The adjusted estimate of effect was estimated through testing the significant variables in a multivariable model. The comparisons were done with chi square test. Statistical significance was considered at P 〈 0.05. Results: Of 861 patients of the study, 54% were males and 43% were females; and the mean age of them was 66.51 ± 15.70. We find no statically significant difference between patient’s Glasgow Coma Scale (GCS) in the emergency department (12.87±3.25) and patients GCS in the neurology department (11.77±5.15). There were 18 (2.2%) overdiagnosed of ischemic stroke, 8 (0.9%) misdiagnosed of ischemic stroke and 36 (4.1%) misdiagnosed of hemorrhagic strokes in the emergency department. Conclusion: There was no significant difference between impression of stroke in the emergency department and diagnosis at the neurology department.
    Type of Medium: Online Resource
    ISSN: 2203-1413
    URL: Article
    DOI: 10.7575/aiac.abcmed.v.7n.3p.7
    Language: Unknown
    Publisher: Australian International Academic Centre
    Publication Date: 2019
    detail.hit.zdb_id: 2766886-1
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  • 4
    Online Resource
    Online Resource
    Obesity as an independent risk factor for COVID-19 severity and mortality
    Wiley ; 2023
    In:  Cochrane Database of Systematic Reviews Vol. 2023, No. 6 ( 2023-05-24)
    Details
    In: Cochrane Database of Systematic Reviews, Wiley, Vol. 2023, No. 6 ( 2023-05-24)
    Type of Medium: Online Resource
    ISSN: 1465-1858
    URL: Article
    DOI: 10.1002/14651858.CD015201
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2038950-4
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  • 5
    Online Resource
    Online Resource
    Comparison of global strain values of myocardium in beta-thalassemia major patients with iron load using specific feature tracking in cardiac magnetic resonance imaging
    Springer Science and Business Media LLC ; 2020
    In:  The International Journal of Cardiovascular Imaging Vol. 36, No. 7 ( 2020-07), p. 1343-1349
    Details
    In: The International Journal of Cardiovascular Imaging, Springer Science and Business Media LLC, Vol. 36, No. 7 ( 2020-07), p. 1343-1349
    Type of Medium: Online Resource
    ISSN: 1569-5794 , 1573-0743
    URL: Article
    DOI: 10.1007/s10554-020-01835-3
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2020
    detail.hit.zdb_id: 3163889-2
    detail.hit.zdb_id: 2008950-8
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  • 6
    Online Resource
    Online Resource
    The Relationship between Demographic Factors in Adult Patients with Stroke
    Australian International Academic Centre ; 2020
    In:  Advances in Bioscience and Clinical Medicine Vol. 7, No. 4 ( 2020-01-28), p. 14-
    Details
    In: Advances in Bioscience and Clinical Medicine, Australian International Academic Centre, Vol. 7, No. 4 ( 2020-01-28), p. 14-
    Abstract: Background: Developing countries are challenging with stroke as the third cause of death in developed countries and the most popular neurologic disease which results in disability. This study was designed to assess the relationship between demographic factors and early outcome in adult patients with difference type of stroke. Methods and Materials: A retrospective register review was performed from March 2017 to March 2018. ED medical document (chart) were reviewed by a neurologist or physician to obtain the clinical diagnosis, patient characteristics. Their demographic data (such as age, gender), NIHSS score and MRS score were filled in questionnaire. the significant variables were verified in a multivariable model to achieve an attuned estimate of effect. Results: A total of 861 patients with stroke were included in the analysis; the male and female sex in the statistical population were 56% and 43%; the mean age of the patients was 14.32 ± 61.74. The mean NIHSS (16.08±10.51) & MRS (3.66) scores were evaluated, respectively 47% severe stroke (NICHSS 〉 16). There was no significant relationship between age increase and NIHSS increase (P = 0.86). Conclusion: Aging has a significant relationship with increased stroke. Gender and age differences in risk of stroke outcomes are mostly described by variations in physical characteristics and stroke severity of the patients.
    Type of Medium: Online Resource
    ISSN: 2203-1413
    URL: Article
    DOI: 10.7575/aiac.abcmed.v.7n.4p.14
    Language: Unknown
    Publisher: Australian International Academic Centre
    Publication Date: 2020
    detail.hit.zdb_id: 2766886-1
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  • 7
    Online Resource
    Online Resource
    Demographic study of patients with vertebral column trauma in North-West of Iran trauma center
    Australian International Academic Centre ; 2017
    In:  Advances in Bioscience and Clinical Medicine Vol. 5, No. 1 ( 2017-01-31), p. 25-
    Details
    In: Advances in Bioscience and Clinical Medicine, Australian International Academic Centre, Vol. 5, No. 1 ( 2017-01-31), p. 25-
    Abstract: Background: Spinal Traumatic injuries is the major damage which is associated with morbidity and mortality rates. In this study the epidemiological characteristics of trauma, spine and their relationship to outcome were investigated. Methods: In this cross sectional study, patients’ information such as age, sex, type of injury, severity of injury, site of injury trauma who admitted to Imam Reza hospital from 29 march 2012 to 20 march 2014 were included. We used Chi-square tests to compare the types of injuries associated with the injury and regression methods. Results: The spinal trauma was identified in 105 cases, of which 9/61% were male. 1.18% of patients with incomplete injury, 5/10% 4/71% damage and no injuries were full. 6/48% of vehicle accidents, 22 cases (21%) of motorcycle accidents, 14 cases  3/13% due to the fall, the equivalent of 10 5/9% of pedestrian accidents, the equivalent of 5 7/4% injury 3 people with a knife and the rest of 9/2% were due to other causes. 6 people, equivalent to 2/9% were experiencing mortality. Type of injury, site of injury and injury severity was significantly associated with outcome. Conclusion: accidents caused by motor vehicles (cars and motorcycles) are the most common cause of trauma in spines in our country. Three factors as well as stable or unstable trauma, the severity of the initial injury and the injury as factors influencing outcome were obtained. According to the achievement of the emergency department in the early diagnosis, appropriate management such as surgery in preventing complications and improving outcome becomes more clear.Key words: Trauma; Spine;
    Type of Medium: Online Resource
    ISSN: 2203-1413
    URL: Article
    DOI: 10.7575/aiac.abcmed.17.05.01.04
    Language: Unknown
    Publisher: Australian International Academic Centre
    Publication Date: 2017
    detail.hit.zdb_id: 2766886-1
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  • 8
    Online Resource
    Online Resource
    Characteristics of Patients with Tramadol Use or Abuse: A Systematic Review and Meta-Analysis
    Galenos Yayinevi ; 2020
    In:  Eurasian Journal of Emergency Medicine Vol. 19, No. 3 ( 2020-9-8), p. 127-135
    Details
    In: Eurasian Journal of Emergency Medicine, Galenos Yayinevi, Vol. 19, No. 3 ( 2020-9-8), p. 127-135
    Type of Medium: Online Resource
    ISSN: 2149-5807 , 2149-6048
    URL: Journal
    URL: Article
    DOI: 10.4274/eajem.
    DOI: 10.4274/eajem.galenos.2020.71473
    Language: Unknown
    Publisher: Galenos Yayinevi
    Publication Date: 2020
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  • 9
    Online Resource
    Online Resource
    Prenatal Administration of Betamethasone and Neonatal Respiratory Distress Syndrome in Multifetal Pregnancies: A Randomized Controlled Trial
    Bentham Science Publishers Ltd. ; 2020
    In:  Current Clinical Pharmacology Vol. 15, No. 2 ( 2020-10-14), p. 164-169
    Details
    In: Current Clinical Pharmacology, Bentham Science Publishers Ltd., Vol. 15, No. 2 ( 2020-10-14), p. 164-169
    Abstract: Neonatal Respiratory Distress Syndrome (NRDS) is one of the most frequent causes of neonatal mortality especially in premature infants. Although it has been well established that maternal antenatal corticosteroid therapy has a positive effect on NRDS reduction, yet the effectiveness of this treatment in multifetal pregnancies is dubious. Objective: We aimed to investigate the effect of betamethasone therapy on the incidence of NRDS in multifetal pregnancies through a randomized controlled trial. Method: 140 women with a multifetal pregnancy at less than 28 weeks’ gestational age were randomly allocated into intervention and control groups. Women at the intervention group received intramuscularly betamethasone (12 mg/kg/BW twice). Neonatal outcomes were evaluated between two groups of intervention and control, and two subgroups of preterm and term births. This study is registered with the Iranian Clinical Trials Registry, number IRCT20180227038879N1. Result: The incidence of NRDS was significantly lower in infants of betamethasone group than the ones in the control group (4.9% vs 18.1%, P=0.034) while it did not show a significant reduction in preterm infants compared to mature ones. Also, the intervention group presented a significant lower neonatal ventilation than the control group (47.2% vs 63.2%, P=0.041). Other neonatal outcomes, including age at birth, birth weight, Apgar score, NICU admission, and the number of mortalities were not significantly different between study groups. Conclusion: Betamethasone therapy during 28-32 weeks of gestation in multifetal pregnancies was associated with better neonatal outcomes through significant reductions in NRDS incidence and requiring ventilator treatment. However, betamethasone administration did not reduce the chance of NRDS in premature infants.
    Type of Medium: Online Resource
    ISSN: 1574-8847
    URL: Article
    DOI: 10.2174/1574884714666191007154936
    Language: English
    Publisher: Bentham Science Publishers Ltd.
    Publication Date: 2020
    SSG: 15,3
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  • 10
    Online Resource
    Online Resource
    An evidence‐based systematic review of the off‐label uses of lisinopril
    Wiley ; 2018
    In:  British Journal of Clinical Pharmacology Vol. 84, No. 11 ( 2018-11), p. 2502-2521
    Details
    In: British Journal of Clinical Pharmacology, Wiley, Vol. 84, No. 11 ( 2018-11), p. 2502-2521
    Abstract: Lisinopril is an angiotensin‐converting‐enzyme inhibitor that is largely administered for off‐label uses. This study aims to provide a comprehensive review of off‐label uses of lisinopril to aid physicians to make evidence‐based decisions. Methods The following bibliographic databases were searched from inception up to 30 March 2017: PubMed, EMBASE, the Cochrane Library, Cochrane Central Register of Controlled Trials, Scopus, Ovid and Proquest. This systematic review sought all randomized trials conducted on adult individuals comparing lisinopril on its off‐label uses with alternative drugs or placebos and reported direct or alternative clinical outcomes. Risk of bias assessment by using the Cochrane Collaboration risk‐of‐bias tool and quality evaluation took place. Results Included studies demonstrated significant positive effects of lisinopril on proteinuric kidney disease; however, lisinopril caused a slight reduction of glomerular filtration rate (GFR) especially for patients with GFR  〈  90 ml min –1 . Lisinopril offered better outcomes in comparison to other standard treatments of diabetic nephropathy. Other studies showed positive effects of lisinopril for migraine, prevention of diabetes, myocardial fibrosis, mitral valve regurgitation, cardiomyopathy in patients with Duchenne muscular dystrophy, oligospermia and infertility, and diabetic retinopathy. Conversely, the studies reported that lisinopril was ineffective for five other off‐label uses. Conclusions The identified studies showed that lisinopril was highly effective for proteinuric kidney disease with a minor but inconsiderable decrease in GFR. Positive effects of lisinopril were demonstrated in seven other off‐label uses; however, lisinopril cannot be recommended as the first choice for these until further clinical trials confirm these positive effects.
    Type of Medium: Online Resource
    ISSN: 0306-5251 , 1365-2125
    URL: Issue
    URL: Article
    DOI: 10.1111/bcp.v84.11
    DOI: 10.1111/bcp.13705
    RVK:
    XA 33650
    Language: English
    Publisher: Wiley
    Publication Date: 2018
    detail.hit.zdb_id: 1498142-7
    SSG: 15,3
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