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  • 1
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    Wasted myocardial work may affect left ventricular remodelling occurrence after primary percutaneous coronary revascularization
    Oxford University Press (OUP) ; 2022
    In:  European Heart Journal - Cardiovascular Imaging Vol. 23, No. Supplement_1 ( 2022-02-04)
    Details
    In: European Heart Journal - Cardiovascular Imaging, Oxford University Press (OUP), Vol. 23, No. Supplement_1 ( 2022-02-04)
    Abstract: Type of funding sources: None. Introduction Left ventricular function recovery (LV-REC) or left ventricular adverse remodelling (LV-REM) after acute myocardial infarction (AMI) play an important role for identifying patients at risk of heart failure. Purpose In this study we aim to evaluate the usefulness of non-invasive myocardial work (MW), a new index of global and regional myocardial performance, to predict LV-REC or LV-REM after AMI. Methods Fifty patients with AMI (mean age, 63,8 ±13,4 years), treated by primary percutaneous coronary intervention (PCI), were prospectively enrolled.  They underwent a baseline transthoracic Doppler echocardiography (TTE) within 48 hours after PCI and a second TTE after a median of 31 days during the follow-up. MW was derived from the strain-pressure loops, integrating in its calculation the non-invasive arterial pressure, according to standard speckle tracking echocardiography recommendations. LV-REC was defined as an absolute improvement of left ventricular ejection fraction (LVEF) ≥ 5% from LVEF at baseline, whereas LV-REM was defined as an increase of ≥ 20% of the LV end diastolic volume (LVEDV) at 1 month follow up. Results We overall found a significant improvement from baseline to one-month follow-up for values of LVEF (49,8 ± 9,5 % vs 52,8 ± 9,3 %, p = 0.001), Global Longitudinal Strain (GLS) (-13,4 ± 3,9 % vs -18,7 ± 5,4 %, p = 0.016), Global Work Index (GWI) (1368,6 ±435,2 vs 1788 ±493 mmHg/%, p = 0.0001), Global Work Efficiency (GWE) (89,96 ± 9,3 % vs 91,3 ± 6,4 %,  p = 0.001), Global Constructive Work (GCW) (1619,16 ± 497,9 mmHg/% vs 2008,6 ± 535,3 mmHg/%, p = 0.0001), Global Wasted Work (GWW) (188,8 ± 19,8 mmHg/% vs 149,2 ± 16,5 mmHg/%). However, LV-REC at 1 month of follow-up was observed only in 36 % of the population enrolled, whereas LV-REM was described in 18% of cases. Using ROC curve analysis, we identified a cut off value of 202 mmHg/% for baseline GWW (Sensitivity 75%, Specificity 62%, AUC 0.6667, CI 95%: 0,51618 - 0,81715, p =0.0001) to identify patients with LV-REM at 1 month. With regards to conventional echo parameters, patients with LV-REC showed lower baseline Wall Motion Score Index (WMSI) than those without LV-REC (1,73 vs 1,38, p = 0.007). Conclusions Among standard and advanced TTE parameters, only baseline GWW is able to predict early LV-REM at 1 month after primary PCI. Therefore, it could be used during baseline evaluation of AMI patients for a more accurate stratification of those at higher risk of heart failure. However, further larger scale studies are needed to validate these findings. Abstract table 1  Abstract table 2
    Type of Medium: Online Resource
    ISSN: 2047-2404 , 2047-2412
    URL: Article
    DOI: 10.1093/ehjci/jeab289.107
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2022
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  • 2
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    Diagnostic accuracy of smartwatch in detecting atrial fibrillation: a systemic review and meta-analysis
    Oxford University Press (OUP) ; 2023
    In:  Europace Vol. 25, No. Supplement_1 ( 2023-05-24)
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    In: Europace, Oxford University Press (OUP), Vol. 25, No. Supplement_1 ( 2023-05-24)
    Abstract: Type of funding sources: None. Introduction Atrial fibrillation (AF) is the most common sustained arrhythmia and an important risk factor for stroke and heart. Recent technology advances allowed for heart rhythm monitoring using Smartwatches which can be used for early AF diagnosis. Purpose We performed a systemic review and meta-analysis to assess the accuracy of AF diagnosis by smartwatches. Methods We systematically searched Medline, Embase and Cochrane electronic databases up to September 28th, 2022 for observational studies of the diagnostic accuracy of smartwatches devices in detecting AF. Studies with 12-lead ECG or single-lead ECG interpreted by a cardiologist as gold standard were included. We calculated the area under the curve (AUC) of the summary receiver operating characteristic curves (SROC) and pooled sensitivities and specificities. Results A total of 20 studies were included enrolling 3447 patients, 57%(95% CI: 55-59%) male with average age of 68.3years (95% CI: 63 – 74). The pooled prevalence of AF was found to be 40% (95% CI 27 – 53%). In the overall analysis of all smartwatches, the AUC was 0.99 (95% CI: 0.98-1.00) (Figure 1), the sensitivity 94%(95% CI: 90 – 96%) and the specificity 97%(95% CI: 95 – 98%) (Figure 2). Smartwatches in primary prevention showed an AUC of 0.97 (95% CI: 0.96-0.99), sensitivity of 83%(95% CI: 52 – 96%) and specificity of 98%(95% CI: 87 – 100%) whereas in secondary prevention showed an AUC of 0.99 (95% CI: 0.98-1.00), sensitivity of 95%(95% CI: 94 – 97%) and specificity of 97%(95% CI: 96 – 98%). In the subgroup analysis by technology, smartwatches with single lead ECG showed an AUC of 0.99 (95% CI: 0.98-1.00), sensitivity of 95%(95% CI: 89 – 97%) and specificity of 97%(95% CI: 94 – 99%) whereas smartwatches with photoplethysmography pulse waveform technology showed an AUC of 0.99 (95% CI: 0.97-0.99), sensitivity of 95%(95% CI: 92 – 96%) and specificity of 97%(95% CI: 95 – 99%). Conclusions Smartwatches proved an excellent diagnostic accuracy for AF diagnosis.
    Type of Medium: Online Resource
    ISSN: 1099-5129 , 1532-2092
    URL: Article
    DOI: 10.1093/europace/euad122.646
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2023
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  • 3
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    The CLUE trigger: a VME based two level trigger for VHE experiments
    Elsevier BV ; 1998
    In:  Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment Vol. 409, No. 1-3 ( 1998-05), p. 679-681
    Details
    In: Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Elsevier BV, Vol. 409, No. 1-3 ( 1998-05), p. 679-681
    Type of Medium: Online Resource
    ISSN: 0168-9002
    URL: Article
    DOI: 10.1016/S0168-9002(97)01350-8
    RVK:
    UA 5680.A
    Language: English
    Publisher: Elsevier BV
    Publication Date: 1998
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  • 4
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    The CLUE experiment operating with 4 telescopes in La Palma
    Elsevier BV ; 1998
    In:  Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment Vol. 409, No. 1-3 ( 1998-05), p. 488-491
    Details
    In: Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Elsevier BV, Vol. 409, No. 1-3 ( 1998-05), p. 488-491
    Type of Medium: Online Resource
    ISSN: 0168-9002
    URL: Article
    DOI: 10.1016/S0168-9002(98)00133-8
    RVK:
    UA 5680.A
    Language: English
    Publisher: Elsevier BV
    Publication Date: 1998
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  • 5
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    Reconstruction of showers at TeV energy by the CLUE experiment and its application to recent data
    Elsevier BV ; 1999
    In:  Nuclear Physics B - Proceedings Supplements Vol. 75, No. 1-2 ( 1999-3), p. 373-376
    Details
    In: Nuclear Physics B - Proceedings Supplements, Elsevier BV, Vol. 75, No. 1-2 ( 1999-3), p. 373-376
    Type of Medium: Online Resource
    ISSN: 0920-5632
    URL: Article
    DOI: 10.1016/S0920-5632(99)00296-0
    Language: English
    Publisher: Elsevier BV
    Publication Date: 1999
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  • 6
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    First Report of Bacterial Blight of Strelitzia augusta Caused by Pseudomonas syringae pv. lachrymans
    Scientific Societies ; 2005
    In:  Plant Disease Vol. 89, No. 9 ( 2005-09), p. 1010-1010
    Details
    In: Plant Disease, Scientific Societies, Vol. 89, No. 9 ( 2005-09), p. 1010-1010
    Abstract: White bird of paradise tree (Strelitzia augusta Thunb.), originally from South Africa, is a tender perennial cultivated as an ornamental plant and is used in gardens in Italy. During February of 2004, a new blight disease was noticed on potted S. augusta at different ages (6 months to 4 years) in several commercial nurseries of eastern Sicily. Field inspections revealed disease incidences as high as 40%. Initial symptoms were small, water-soaked leaf spots that expanded throughout the veins in dark brown streaks. Stem cross sections revealed browning of the vascular tissues, which might involve the entire stem. In some cases, the necrosis extended to the apical bud, causing death of the plant. Thirty explants from infected tissues were washed in sterile water and plated on plate count agar (PCA) from which two types of bacterial colonies were consistently isolated. Pathogenicity tests were performed on S. augusta plants. Twenty-four plants were inoculated (12 per bacterial isolate) using two different procedures: spray with a bacterial suspension (10 6 CFU/ml) and wounding with an infected needle on the midribs. The same number of noninoculated plants was used as controls. All plants were maintained at 24 to 26°C with 95 to 100% relative humidity until symptoms occurred 4 days later. Just one of the two tested bacterial types was pathogenic. The symptoms were similar to those previously observed in the field. No symptoms were observed in the plants spray inoculated with the bacterial suspension, proving that the bacteria were unable to infect in the absence of a wound. The controls showed no symptoms. Koch's postulates were fulfilled by the reisolation of the infective strain which was sent to the CBS (Centraalbu-reau voor Schimmelcultures) and identified as Pseudomonas syringae pv. Lachrymans/pisi using the Biolog MicroLog3 4.01C program (Biolog Inc., Hayward, CA). Further pathogenicity tests have been carried out on zucchini and pea pods to characterize the pathovar using 48SR1 of P. syringae pv. syringae and B4 of P. syringae pv. pisi as reference strains. Necrotic, sunken, water-soaked spots surrounded by a chlorotic halo, reported in the literature as typical symptoms of P. syringae pv. lachry-mans (Smith & Bryan) Young, Dye & Wilkie (1), were observed on zucchini when inoculated with our strain. Our P. syringae strain did not cause the typical symptoms of P. syringae pv. pisi on inoculated pea pods. The results of the pathogenicity tests and the inability of the P. syringae strain isolated from S. augusta to utilize homoserine, used to discriminate pv. pisi from other pathovars of P. syringae, allowed us to identify the strain as P. syringae pv. lachrymans. Low temperature damage and late transplant may have promoted the spread of the disease in the nurseries. Under these conditions, the economic importance of this disease for the crop can be considered high. To our knowledge, this is first report of P. syringae pv. lachrymans on S. augusta. Reference: (1) K. Pohronezny et al. Plant Dis. Rep. 62:306, 1978.
    Type of Medium: Online Resource
    ISSN: 0191-2917 , 1943-7692
    URL: Article
    DOI: 10.1094/PD-89-1010A
    Language: English
    Publisher: Scientific Societies
    Publication Date: 2005
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  • 7
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    Axillary vein puncture versus cephalic vein cutdown for cardiac implantable electronic device implantation: a meta-analysis
    Oxford University Press (OUP) ; 2023
    In:  Europace Vol. 25, No. Supplement_1 ( 2023-05-24)
    Details
    In: Europace, Oxford University Press (OUP), Vol. 25, No. Supplement_1 ( 2023-05-24)
    Abstract: Type of funding sources: None. Introduction Cephalic vein cutdown (CVC) and axillary vein puncture (AVP) are both recommended for transvenous implantation of leads for cardiac implantable electronic devices (CIEDs). Nonetheless, it is still debated which of the two techniques has a better safety and efficacy profile. Methods We systematically searched Medline, Embase and Cochrane electronic databases up to September 5th, 2022, for studies that evaluated the efficacy and safety of AVP and CVC reporting at least one clinical outcome of interest. The primary endpoint was acute procedural success. The effect size was estimated using a random-effect model as Risk Ratio (RR) and relative 95% Confidence Interval (CI). Results Overall, 8 studies were included, which enrolled 1926 patients and 3532 transvenous lead implants [66.3% (n=1277) males with an average age of 72.3±14.8 years]. Compared to CVC, AVP showed a significant increase in the primary endpoint (95.7 % vs 76.1 %; RR: 1.24; 95% CI: 1.09-1.40; p=0.001) (Figure 1). Total procedural time (Mean Difference [MD] : -8.25 min; 95%CI: -10.23- -6.27; p & lt;0.0001; I2 =0%) and venous access time (MD: -6.24 min; 95%CI: -7.01- -5.47; p & lt;0.0001; I2 =0%) were significantly shorter with AVP compared to CVC. No differences were found between AVP and CVC for incidence of pneumothorax (RR: 0.72; 95% CI: 0.13 - 4.0; p=0.71), lead failure (RR: 0.58; 95% CI: 0.23-1.48; p=0.26), pocket hematoma/bleeding (RR: 0.58; 95% CI: 0.15- 2.23; p=0.43), device infection (RR: 0.95; 95% CI: 0.14- 6.60; p=0.96) and fluoroscopy time (MD: -0.24 min; 95%CI: -0.75- 0.28; p=0.36). Conclusion Our meta-analysis suggests that AVP may improve procedural success and reduce total procedural time and venous access time compared to CVC.
    Type of Medium: Online Resource
    ISSN: 1099-5129 , 1532-2092
    URL: Article
    DOI: 10.1093/europace/euad122.400
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2023
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  • 8
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    First Report of Southern Blight Caused by Sclerotium rolfsii on Laurustinus
    Scientific Societies ; 2004
    In:  Plant Disease Vol. 88, No. 3 ( 2004-03), p. 310-310
    Details
    In: Plant Disease, Scientific Societies, Vol. 88, No. 3 ( 2004-03), p. 310-310
    Abstract: Laurustinus (Viburnum tinus L.), native to the Mediterranean Region, is an evergreen shrub commonly used as a specimen shrub or small tree or used in border plantings. During August 2003, a blight occurred on 2-year-old-plants of laurustinus growing in pots in a nursery in eastern Sicily (Italy). Disease incidence ranged from 2 to 5% across the field. Symptoms included 3 to 4 cm long lesions and the development of white mycelial strands and brown, 1.0 to 1.8 mm, nearly spherical sclerotia on the crown of plants at the soil line that are typical of Sclerotium rolfsii Sacc. The foliage of infected plants wilted, followed by a sudden collapse of the plant. The fungus was consistently isolated on acidified potato dextrose agar (PDA) (pH 4.5) by plating symptomatic tissues that were surface disinfested (1.2% NaOCl) for 1 min. and rinsed in sterile water. Pathogenicity tests were performed by sprinkling 50 sclerotia, obtained from infected oat kernels (2), on the soil surface around the collar of each of 10 healthy, potted 1-year-old plants of laurustinus. Five of the plants were previously wounded on the crown 1.5 cm above or below the soil line with a sterile needle. Five noninoculated plants served as controls. All plants were maintained at 25 ± 2°C and enclosed for 72 hr in polyethylene bags (90 to 95% relative humidity). Blight symptoms similar to those seen in nursery were observed on inoculated plants 20 to 25 days after inoculation, while no symptoms developed on control plants. Koch's postulates were fulfilled by reisolation of the fungus on acidified PDA from all infected laurustinus plants. S. rolfsii was previously recorded on Prague viburnum (Viburnum × pragense L.) as the causal agent of southern blight (1). To our knowledge, this is the first report of southern blight caused by S. rolfsii on laurustinus. References: (1) A. Hagan. Southern blight on flowers, shrubs, and trees. On-line publication ANR-1157. Alabama A & M, and Auburn University ( www.aces.edu/dept/extcomm/publications/html ). (2) R. Rodriguez-Kabana et al. Plant Dis. Rep. 59:5, 1975.
    Type of Medium: Online Resource
    ISSN: 0191-2917 , 1943-7692
    URL: Article
    DOI: 10.1094/PDIS.2004.88.3.310B
    Language: English
    Publisher: Scientific Societies
    Publication Date: 2004
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  • 9
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    First Report of Crown Rot and Root Rot Caused by Cylindrocladium pauciramosum on Feijoa ( Feijoa sellowiana ) in Italy
    Scientific Societies ; 2008
    In:  Plant Disease Vol. 92, No. 11 ( 2008-11), p. 1590-1590
    Details
    In: Plant Disease, Scientific Societies, Vol. 92, No. 11 ( 2008-11), p. 1590-1590
    Abstract: Feijoa sellowiana (O. Berg) O. Berg is native to South America and grown in Italy as an ornamental plant and for its fruit. During 2006, 2007, and 2008, a severe wilting was noticed on ∼ 10,000 potted 6-month to 3-year-old plants obtained from seeds and produced by three commercial nurseries in Catania Province (southern Italy). Wilting was always associated with root rot and brown discoloration at the base of the stem. Leaf spots or stem lesions were not observed. A Cylindrocladium sp. was isolated consistently from the crown, basal stem, and roots of symptomatic plants on potato dextrose agar (PDA). Ten isolates of a Cylindrocladium sp. were obtained from single-spore colonies made from a 14-day-old culture grown on PDA and subsequently subcultured on carnation leaf agar (CLA). Cultures were incubated at 25°C under near-UV light with a 12-h light/dark regimen and examined after 7 days (1). Only fungal structures occurring on the carnation leaf tissue were examined. Isolates were identified based on morphological traits and mating type responses (2,4). Isolates were mated with opposite mating tester strains of C. pauciramosum (DISTEF-G128 [MAT1-1] and DISTEF-G87 [MAT1-2] ) and C. scoparium (DISTEF-GCs7 = CBS 120892 [MAT1-1] and DISTEF-GP0 = CBS 119669 [MAT1-2] ) selected from an Italian collection. Plates were parafilmed, sealed in plastic bags, incubated in a chamber at 25 ± 1°C with a photoperiod of 16 h of light and 8 h of darkness, and examined weekly until perithecia developed. Successful crosses were determined after 2 months of incubation and were regarded as those isolate combinations that produced perithecia with viable ascospores. Conidia were observed to be 30 to 60 × 3.5 to 5.0 μm while conidiophores mostly had two to three series of branches and stipes terminated in obpyriform to broadly ellipsoidal vesicles, which is characteristic of C. pauciramosum C.L. Schoch and Crous (teleomorph Calonectria pauciramosa C.L. Schoch and Crous). Fertile perithecia containing viable ascospores were similar to Calonectria pauciramosa. They were obtained only from crosses of the examined isolates with mating type testers of C. pauciramosum. Six isolates (when paired with DISTEF-G128) and four isolates (when mated with DISTEF-G87) provided fertile progeny. No perithecia were obtained in pairings of the 10 isolates with tester strains of C. scoparium. One representative isolate was deposited at the Fungal Biodiversity Centre, Centraalbureau voor Schimmelcultures (DISTEF-AS4 = CBS-120618). Koch's postulates were fulfilled by inoculating 30 6-month-old seedlings of feijoa with a spore suspension (10 5 conidia per ml) of one isolate of the pathogen (DISTEF-AS4) grown on CLA for 14 days. The same number of seedlings was used as a control. Following inoculation, plants were maintained in a growth chamber at 25 ± 1°C and 90 to 95% relative humidity. Wilting, crown rot, and root rot symptoms identical to those observed in the nurseries appeared within 15 to 50 days. Symptoms were not observed on the control plants. C. pauciramosum was previously reported to cause leaf spots on feijoa (3). To our knowledge, this is the first report of wilting due to crown and root rot caused by C. pauciramosum in this host. The disease is a limiting factor for feijoa cultivation in Sicilian nurseries. References: (1) P. W. Crous et al. Mycologia 84:497, 1992. (2) P. W. Crous and M. J. Wingfield. Mycotaxon 51:341, 1994. (3) G. Polizzi and V. Catara. Plant Dis. 85:803, 2001. (4) C. L. Schoch et al. Mycologia 91:286, 1999.
    Type of Medium: Online Resource
    ISSN: 0191-2917 , 1943-7692
    URL: Article
    DOI: 10.1094/PDIS-92-11-1590B
    Language: English
    Publisher: Scientific Societies
    Publication Date: 2008
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  • 10
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    First Report of Stem Blight Caused by Botrytis cinerea on Jasminum officinalis in Italy
    Scientific Societies ; 2008
    In:  Plant Disease Vol. 92, No. 12 ( 2008-12), p. 1708-1708
    Details
    In: Plant Disease, Scientific Societies, Vol. 92, No. 12 ( 2008-12), p. 1708-1708
    Abstract: Common jasmine (Jasminum officinalis L.) is an evergreen shrub that is native to the Middle and Far East. It is widely grown in Europe as an ornamental plant and in southeastern France for fragrance for the perfume industry. In March of 2008, a previously undescribed disease was observed on potted (6-month- to 3-year-old) common jasmine plants growing in open fields in a nursery of eastern Sicily, Italy. More than 20% of the plants showed disease symptoms. Diseased plants had small to large, brown or black lesions on stem. The lesions expanded rapidly, girdled the stem and caused blight of entire branches, and occasionally killed the plant. Abundant conidia and mycelia were detected on the surface of dead and dying stems under cool and humid conditions, which resulted in a moldy gray appearance. Botrytis cinerea Pers.:Fr. (1) was consistently isolated from affected tissues disinfected for 1 min in 1% NaOCl, rinsed in sterile water, and plated on potato dextrose agar (PDA). Colonies were at first white then became gray after 6 to 7 days when spores differentiated. White sclerotia developed after 8 to 9 days and turned black with age. Size of the conidia produced on 1-month-old culture ranged from 5.0 to 9.5 × 6.5 to 12.5 μm on the basis of 50 spore measurements. Sclerotia were spherical or irregular and ranged from 1.0 to 2.5 × 0.9 to 2.9 mm (average 1.7 × 1.8 mm). Stems of eight 6-month-old common jasmine plants were lightly wounded with a sterile razor and inoculated with 3-mm-diameter plugs of PDA from 10-day-old mycelial cultures, eight similar plants were inoculated with mycelium without wounding, and an equal number of noninoculated plants inoculated with only PDA plugs served as control. After inoculation, plants were enclosed in transparent plastic bags at 20 ± 2°C for 5 days. Stem lesions identical to the ones observed in the nursery were detected on all wounded and on two nonwounded fungus-inoculated plants within 5 to 7 days. Control plants remained healthy. B. cinerea was reisolated from typical lesions. The unusually cool and humid weather conditions recorded in Sicily are supposed to be highly conducive of disease outbreak. Although B. cinerea does not usually kill the plants, under these environmental conditions this disease can cause significant economic loss to ornamental nurseries. To our knowledge, this is the first report of B. cinerea causing stem blight on J. officinalis. Reference: (1) M. B. Ellis. Dematiaceous Hyphomycetes. CAB, Kew, Surrey, England, 1971.
    Type of Medium: Online Resource
    ISSN: 0191-2917 , 1943-7692
    URL: Article
    DOI: 10.1094/PDIS-92-12-1708B
    Language: English
    Publisher: Scientific Societies
    Publication Date: 2008
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