In:
Geriatrics & Gerontology International, Wiley, Vol. 14, No. S1 ( 2014-02), p. 115-121
Abstract:
Our aim was to clarify the association between type 2 diabetes and the risk of low muscle mass in older adults. Methods In the present study, 414 adults aged 65 years or older (144 patients with type 2 diabetes and 270 control participants) were included. Body composition was measured by dual‐energy X ‐ray absorptiometry. Low muscle mass was defined as the appendicular skeletal muscle mass/height 2 ( ASM /Ht 2 ) or appendicular skeletal muscle mass/weight ( ASM / W t) of 〈 2 SD below the sex‐specific normal mean of the young reference group, or 〈 lower 20th percentile of total body skeletal muscle mass/weight ( TSM / W t) from control participants. Results Older men with type 2 diabetes showed significantly lower appendicular skeletal muscle mass than those without diabetes (19.5 ± 3.5 kg vs 21.0 ± 2.8 kg, P 〈 0.001). The prevalence of low muscle mass was consistently higher in older men with diabetes than those without diabetes defined by ASM / H t 2 (57.6% vs 41.5%, P = 0.040), ASM / W t (23.7% vs 12.3%, P = 0.046) and TSM / W t (49.2% vs 20.0%, P 〈 0.001). In older women with diabetes, the prevalence of low muscle mass was higher than those without diabetes by ASM / W t (25.9% vs 15.0%, P = 0.044) and TSM / W t (32.9% vs 20.0%, P = 0.030), but not by ASM / H t 2 (7.1% vs 8.6%, P = 0.685). The risk of low muscle mass was approximately two‐ to fourfold higher in older adults with type 2 diabetes, even after adjusting for age, body mass index, current smoking and other risk factors. Conclusions In K orean older adults, type 2 diabetes is associated with low muscle mass. G eriatr G erontol I nt 2014; 14 (Suppl. 1): 115–121.
Type of Medium:
Online Resource
ISSN:
1444-1586
,
1447-0594
DOI:
10.1111/ggi.2014.14.issue-s1
Language:
English
Publisher:
Wiley
Publication Date:
2014
detail.hit.zdb_id:
2078308-5
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