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  • 1
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2017
    In:  Infectious Diseases in Clinical Practice Vol. 25, No. 5 ( 2017-9), p. 260-263
    In: Infectious Diseases in Clinical Practice, Ovid Technologies (Wolters Kluwer Health), Vol. 25, No. 5 ( 2017-9), p. 260-263
    Abstract: The aim of this study was to identify causative organisms of acute rhinosinusitis in immunosuppressed patients by a retrospective chart review. Methods Records were reviewed using International Classification of Disease, Ninth Edition codes for inpatient treatment of acute sinusitis. Patients were included only if they had formal sinus cultures obtained and were immunosuppressed, either carrying a diagnosis of a hematologic malignancy or receiving chemotherapy. Demographics, underlying malignancy, and culture results were recorded. Results Records of 74 patients with 104 cultures were obtained. There were 43 males and 31 females. The mean age was 51. The most common primary diagnoses were leukemia (65%) and lymphoma (23%). Sixty cultures resulted in either no growth or growth of usual respiratory flora. Of the 44 positive cultures, 5 were polymicrobial, resulting in 61 organisms isolated in total. Bacteria cultured were 73% Gram positive, whereas 27% were Gram negative. The most common Gram-positive organisms cultured were Staphylococcus species. Pseudomonas species were the predominant Gram-negative bacteria. Thirteen samples grew fungal organisms. Conclusions Medical management of sinusitis in an immunosuppressed patient seems to be adequate in most cases. Patients who fail to improve should undergo evaluation by an otolaryngologist to obtain cultures for directed antibiotic therapy. Infections by Staphylococcus species as well as quinolone- and cephalosporin-resistant Gram-negative organisms may be encountered, and clinicians should suspect their presence in patients with persistent disease and expand their antibiotic coverage appropriately.
    Type of Medium: Online Resource
    ISSN: 1536-9943 , 1056-9103
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2017
    detail.hit.zdb_id: 2062211-9
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  • 2
    Online Resource
    Online Resource
    Informa UK Limited ; 2011
    In:  Computer Aided Surgery Vol. 16, No. 2 ( 2011-03), p. 47-53
    In: Computer Aided Surgery, Informa UK Limited, Vol. 16, No. 2 ( 2011-03), p. 47-53
    Type of Medium: Online Resource
    ISSN: 1092-9088 , 1097-0150
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2011
    detail.hit.zdb_id: 2006641-7
    detail.hit.zdb_id: 2870722-9
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  • 3
    Online Resource
    Online Resource
    SAGE Publications ; 2005
    In:  Cancer Control Vol. 12, No. 4 ( 2005-10), p. 242-247
    In: Cancer Control, SAGE Publications, Vol. 12, No. 4 ( 2005-10), p. 242-247
    Type of Medium: Online Resource
    ISSN: 1073-2748 , 1073-2748
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2005
    detail.hit.zdb_id: 2004182-2
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  • 4
    In: Cancer, Wiley, Vol. 122, No. 4 ( 2016-02-15), p. 634-641
    Abstract: Human papillomavirus‐positive oropharyngeal cancer has a low incidence of failure and toxicity with modern treatment techniques, with the majority of events occurring within the first 6 months of follow‐up. Optimizing management in this rapidly growing population may be achieved by deescalation of follow‐up intensity.
    Type of Medium: Online Resource
    ISSN: 0008-543X , 1097-0142
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2016
    detail.hit.zdb_id: 1479932-7
    detail.hit.zdb_id: 2599218-1
    detail.hit.zdb_id: 2594979-2
    detail.hit.zdb_id: 1429-1
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  • 5
    Online Resource
    Online Resource
    Wiley ; 2002
    In:  The Laryngoscope Vol. 112, No. 7 ( 2002-07), p. 1201-1203
    In: The Laryngoscope, Wiley, Vol. 112, No. 7 ( 2002-07), p. 1201-1203
    Abstract: Parasitic infections, especially Acanthamoeba, are rarely implicated as a specific cause of rhinosinusitis. It is a fatal disease found in the immunocompromised population, in particular in patients infected with the human immunodeficiency virus (HIV). Less than 10 cases of Acanthamebic rhinosinusitis have been reported in the literature, and only 1 has survived. This case report presents an Acanthamebic infection misdiagnosed as a squamous cell carcinoma of the nasal septum on a presumptive healthy, immunocompetent 35‐year‐old woman. She was later diagnosed with AIDS (AIDS) along with disseminated Acanthamoebiasis and became the second reported case surviving this deadly illness. This case report also discusses the difficulty in diagnosing this rare parasite, the pathogenesis, and the multidisciplinary treatment required to control and manage this uniformly fatal disease.
    Type of Medium: Online Resource
    ISSN: 0023-852X , 1531-4995
    Language: English
    Publisher: Wiley
    Publication Date: 2002
    detail.hit.zdb_id: 2026089-1
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  • 6
    Online Resource
    Online Resource
    Archives of Pathology and Laboratory Medicine ; 2000
    In:  Archives of Pathology & Laboratory Medicine Vol. 124, No. 8 ( 2000-08-01), p. 1179-1184
    In: Archives of Pathology & Laboratory Medicine, Archives of Pathology and Laboratory Medicine, Vol. 124, No. 8 ( 2000-08-01), p. 1179-1184
    Abstract: Context.—Hyalinizing spindle cell tumor with giant rosettes is a recently described biphasic neoplasm of soft tissues that shares mesenchymal and neuroendocrine features. Its morphologic structure is distinctive, with the presence of hyalinized paucicellular foci that are termed rosettes. The cells around the latter display positive immunoreactivity for neuroendocrine markers. The small number of cases described to date indicates that they tend to be localized in the extremities. Objective.—To describe the clinicopathologic features of 2 unusual cases of hyalinizing spindle cell tumor with giant rosettes. Methods and Results.—One tumor was located in the prestyloid parapharyngeal space and the second in the left thigh. Both tumors were well circumscribed and surrounded by a thin capsulelike fibrous band without infiltrating projections. The rosettes were embedded in a spindle cell proliferation. Immunohistochemical stains showed positive results for S100 protein, synaptophysin, CD57, protein gene product 9.5, and neuron-specific enolase exclusively in the cells palisading the rosettes. These markers were negative in the spindle cell portions of the tumor. The latter were immunoreactive for factor XIIIa, vimentin, HAM56, collagen IV, and CD68. Vimentin was the only marker shared by the rosette-forming cells and the spindle cells. Ultrastructurally, the rosette-forming cells contained neurosecretory granules. This study describes the first cytogenetic analysis in this type of tumor revealing 2 cell lines, both containing a balanced translocation between chromosomes 7 and 16. Follow-up of the patients at 16 and 8 months did not disclose evidence of recurrence. Conclusions.—These 2 new cases increase the awareness of hyalinizing spindle cell tumor with giant rosettes and demonstrate that it is a spindle cell neoplasm of unique cytogenetic rearrangements composed of dendritic, histiocytic, and fibroblastic cells admixed with cells that have neuroendocrine differentiation.
    Type of Medium: Online Resource
    ISSN: 1543-2165 , 0003-9985
    RVK:
    RVK:
    Language: English
    Publisher: Archives of Pathology and Laboratory Medicine
    Publication Date: 2000
    detail.hit.zdb_id: 2028916-9
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  • 7
    In: Journal of Anesthesia, Springer Science and Business Media LLC, Vol. 29, No. 2 ( 2015-4), p. 263-268
    Type of Medium: Online Resource
    ISSN: 0913-8668 , 1438-8359
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2015
    detail.hit.zdb_id: 1481564-3
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  • 8
    In: Otolaryngology–Head and Neck Surgery, Wiley, Vol. 153, No. 6 ( 2015-12), p. 943-950
    Abstract: There is no definitive consensus on the impact of preoperative embolization on carotid body paraganglioma management. The purpose of this study was to assess the effects of preoperative embolization on carotid body paraganglioma excision. Data Sources A systematic search was conducted without limits, and it included studies published on or before July 2013 from PubMed, CINAHL, Web of Knowledge, and the Cochrane Library. Relevant synonyms for the search terms “paraganglioma,”“carotid body tumor,” and “embolization” were applied. Review Methods Studies evaluating patients undergoing surgical intervention with embolization for carotid body tumors were included. Two reviewers independently assessed the titles and abstracts for inclusion and extracted the data. The guidelines set forth by the Cochrane Collaboration were followed in the process of data extraction. Data were pooled with a fixed effects model, and standardized mean difference (SMD) and 95% confidence intervals (95% CIs) are reported. Results A total of 22 studies (15 nonrandomized studies with a comparator, 7 single‐arm studies) were included, enrolling 578 patients with 607 tumors. Patients undergoing preoperative embolization had significantly less estimated blood loss compared with those of surgical excision only (12 studies; 295 tumors; SMD: –0.52; 95% CI: –0.77, –0.28). Patients undergoing preoperative embolization had less operative time compared with that of surgical excision only (6 studies; 174 tumors; SMD: –0.46; 95% CI: –0.77, –0.14). Conclusion Surgical excision with preoperative embolization appears to decrease estimated blood loss and operative time when compared with that without preoperative embolization for carotid body paragangliomas.
    Type of Medium: Online Resource
    ISSN: 0194-5998 , 1097-6817
    Language: English
    Publisher: Wiley
    Publication Date: 2015
    detail.hit.zdb_id: 2008453-5
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  • 9
    Online Resource
    Online Resource
    SAGE Publications ; 2007
    In:  Annals of Otology, Rhinology & Laryngology Vol. 116, No. 7 ( 2007-07), p. 525-531
    In: Annals of Otology, Rhinology & Laryngology, SAGE Publications, Vol. 116, No. 7 ( 2007-07), p. 525-531
    Abstract: We describe a cohort of patients with an unusual presentation of stridor, their evaluation and management, and their outcome. We review the pertinent English-language literature. Methods: We performed a retrospective review of the records of 12 adolescent patients treated for acute-onset inspiratory stridor at the Departments of Otolaryngology-Head and Neck Surgery and Allergy and Immunology at the University of South Florida and the Department of Speech Pathology at the H. Lee Moffitt Cancer Center and Research Institute. Two additional patients received treatment elsewhere. Demographic, historical, and laboratory data, physical examination findings, and follow-up information were extracted. A review of both the Hillsborough County Department of Health epidemiological report and the English-language literature was performed. Results: Fourteen female patients who attended a local high school developed audible inspiratory noise. Twelve of the 14 were seen at the University of South Florida Ear, Nose and Throat Center. The remaining 2 patients were evaluated by outside otolaryngologists but were included in all reports from the Department of Health. Environmental studies did not find noxious chemical or biological agents in the students' environments to explain the development of the symptoms. Physical and videostroboscopic examination identified two distinct laryngeal findings causing the audible stridor. One involved paradoxical vocal fold movement, and the other, supraglottic mucosal collapse into the airway. All patients underwent rigorous speech pathology intervention and structured treatment with either complete resolution or significant improvement, seen both clinically and on videostroboscopic evaluation. Conclusions: Audible stridor can arise from numerous disease processes. In the vast majority of presentations it occurs sporadically and on an individual basis. Our cohort is especially unusual because of the sheer number of patients. Our presentation of a case of mass psychogenic illness as the cause of vocal cord dysfunction with additional findings of laryngomalacia within a group of adolescent girls is the first in the English-language literature. The key to the diagnosis is recognition of the disorder and susceptible individuals by using a thorough physical examination with emphasis on the laryngoscopic and videostroboscopic findings. The systematic approach, undertaken by a team including an otolaryngologist, an allergist, a speech pathologist, and an epidemiologist, proved to be effective in the management of this complex disorder and highly unusual situation.
    Type of Medium: Online Resource
    ISSN: 0003-4894 , 1943-572X
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2007
    detail.hit.zdb_id: 2033055-8
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  • 10
    Online Resource
    Online Resource
    SAGE Publications ; 2004
    In:  Cancer Control Vol. 11, No. 3 ( 2004-05), p. 144-151
    In: Cancer Control, SAGE Publications, Vol. 11, No. 3 ( 2004-05), p. 144-151
    Type of Medium: Online Resource
    ISSN: 1073-2748 , 1073-2748
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2004
    detail.hit.zdb_id: 2004182-2
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