GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Online Resource
    Online Resource
    PCR detection of pathogenic Leptospira genomospecies targeting putative transcriptional regulator genes
    Canadian Science Publishing ; 2006
    In:  Canadian Journal of Microbiology Vol. 52, No. 3 ( 2006-03-01), p. 272-277
    Details
    In: Canadian Journal of Microbiology, Canadian Science Publishing, Vol. 52, No. 3 ( 2006-03-01), p. 272-277
    Abstract: The genus Leptospira comprises multiple genomospecies that demonstrate varied pathogenic potential. The availability of rapid and precise diagnostic procedures to differentiate pathogenic from nonpathogenic Leptospira spp. is therefore essential to prevent an otherwise easily treatable malaise from developing into a life-threatening disease. In this report, we conducted an investigation on the diagnostic potential of Leptospira genes encoding putative tran scriptional regulators. While PCR primers derived from transcriptional regulator gene la1137 recognized all 24 pathogenic Leptospira strains representing seven species, those from la1937, la3231, la3825, and la4130 detected 19 of the 24 Leptospira strains. However, none of these primers reacted with four nonpathogenic Leptospira species or other common bacteria. The putative transcriptional regulator genes la1137, la1937, la3231, la3825, and la4130 are present in pathogenic Leptospira strains, making them potential targets for diagnostic applications. Further characterization of these genes and their proteins may help elucidate the molecular mechanisms of leptospiral virulence and pathogenicity and pave the way for potential development of novel control strategies against leptospirosis.Key words: Leptospira, pathogenic, transcriptional regulator gene, PCR, identification.
    Type of Medium: Online Resource
    ISSN: 0008-4166 , 1480-3275
    URL: Article
    DOI: 10.1139/w05-120
    RVK:
    WA 15000
    Language: French
    Publisher: Canadian Science Publishing
    Publication Date: 2006
    detail.hit.zdb_id: 280534-0
    detail.hit.zdb_id: 1481972-7
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    Photosensitization Outbreak in Shorthorn Calves in Missouri
    SAGE Publications ; 1991
    In:  Journal of Veterinary Diagnostic Investigation Vol. 3, No. 2 ( 1991-04), p. 180-182
    Details
    In: Journal of Veterinary Diagnostic Investigation, SAGE Publications, Vol. 3, No. 2 ( 1991-04), p. 180-182
    Type of Medium: Online Resource
    ISSN: 1040-6387 , 1943-4936
    URL: Article
    DOI: 10.1177/104063879100300218
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1991
    detail.hit.zdb_id: 2265211-5
    SSG: 22
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    Intracranial Squamous Cell Carcinoma Causing Horner's Syndrome in a Cow
    SAGE Publications ; 1997
    In:  Journal of Veterinary Diagnostic Investigation Vol. 9, No. 1 ( 1997-01), p. 106-108
    Details
    In: Journal of Veterinary Diagnostic Investigation, SAGE Publications, Vol. 9, No. 1 ( 1997-01), p. 106-108
    Type of Medium: Online Resource
    ISSN: 1040-6387 , 1943-4936
    URL: Article
    DOI: 10.1177/104063879700900124
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1997
    detail.hit.zdb_id: 2265211-5
    SSG: 22
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    Uterine Neoplasia in 13 Cats
    SAGE Publications ; 2003
    In:  Journal of Veterinary Diagnostic Investigation Vol. 15, No. 6 ( 2003-11), p. 515-522
    Details
    In: Journal of Veterinary Diagnostic Investigation, SAGE Publications, Vol. 15, No. 6 ( 2003-11), p. 515-522
    Abstract: Thirteen uterine tumors were diagnosed in 13 cats and accounted for 0.29% of all feline neoplasms received during a 9.6-year period. Age at diagnosis ranged from 3 to 16 years; median 9 years. Six were Domestic Shorthair cats, and 7 were purebred cats of 5 different breeds. Eight adenocarcinomas and 1 mixed Müllerian tumor (adenosarcoma) comprised the endometrial tumors. Myometrial tumors included 3 leiomyomas and 1 leiomyosarcoma. One of the adenocarcinomas developed in the uterine stump of an ovario-hysterectomized cat; the other cats were sexually intact. Concurrent mammary adenocarcinoma was diagnosed in 1 cat with uterine adenocarcinoma and in another with uterine leiomyoma. Tumors were discovered during elective ovariohysterectomy in 2 cats, but at least 3 others had experienced reproductive problems (infertility or pyometra). Five cats presented for abdominal or pelvic masses. Endometrial adenocarcinomas were positive immunohistochemically for cytokeratins and negative for smooth muscle actin (SMA); 1 of 6 cats was positive for vimentin and 4 of 8 were positive for estrogen receptor—α (ERα). Adenosarcoma stromal cells were positive for vimentin and ERα but negative for cytokeratins and SMA. Smooth muscle tumors were positive for vimentin and SMA and negative for cytokeratins. Leiomyomas, but not the leiomyosarcomas, were positive for ERα. Adenocarcinomas in 4 cats had metastasized by the time of ovariohysterectomy. Two other cats were euthanized 5 months after ovariohysterectomy; at least one of these cats had developed an abdominal mass that was not examined histologically. Only 2 cats with endometrial adenocarcinoma had disease-free intervals longer than 5 months after surgery. Metastasis was not detected in any mesenchymal tumor; however, these cats were either euthanized on discovery of the tumor or the tumor was first detected at necropsy.
    Type of Medium: Online Resource
    ISSN: 1040-6387 , 1943-4936
    URL: Article
    DOI: 10.1177/104063870301500602
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2003
    detail.hit.zdb_id: 2265211-5
    SSG: 22
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 5
    Online Resource
    Online Resource
    Parvovirus Infection in Pigs with Exudative Skin Disease
    SAGE Publications ; 1990
    In:  Journal of Veterinary Diagnostic Investigation Vol. 2, No. 3 ( 1990-07), p. 244-246
    Details
    In: Journal of Veterinary Diagnostic Investigation, SAGE Publications, Vol. 2, No. 3 ( 1990-07), p. 244-246
    Type of Medium: Online Resource
    ISSN: 1040-6387 , 1943-4936
    URL: Article
    DOI: 10.1177/104063879000200322
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1990
    detail.hit.zdb_id: 2265211-5
    SSG: 22
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 6
    Online Resource
    Online Resource
    Immunoreactivity of A103, An Antibody to Melan A, in Canine Steroid-Producing Tissues and their Tumors
    SAGE Publications ; 2001
    In:  Journal of Veterinary Diagnostic Investigation Vol. 13, No. 4 ( 2001-07), p. 328-332
    Details
    In: Journal of Veterinary Diagnostic Investigation, SAGE Publications, Vol. 13, No. 4 ( 2001-07), p. 328-332
    Abstract: The monoclonal antibody A103 to the melanocytic differentiation antigen Melan A stains human steroid-producing cells and their tumors. A total of 200 formalin-fixed, paraffin-embedded canine normal tissues and hyperplastic and neoplastic lesions of the adrenal gland, testis, and ovary were immunohistochemically tested for Melan A with antibody A103. Leydig cell tumors (23/23, 100%), Sertoli cell tumors (14/15, 93%), and adrenocortical adenomas (12/13, 92%) were consistently positive. Adrenocortical carcinomas (23/35, 65%) and granulosa cell tumors (10/17, 59%) were less frequently positive. All pheochromocytomas, seminomas, and dysgerminomas were negative. The pattern of staining was cytoplasmic, but nuclear staining was also frequently seen in normal Leydig cells and their tumors. As in human tumors, immunohistochemistry for Melan A stains many canine steroid-producing tumors and can be used to distinguish these tumors from those of nonstereidogenic cells.
    Type of Medium: Online Resource
    ISSN: 1040-6387 , 1943-4936
    URL: Article
    DOI: 10.1177/104063870101300408
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2001
    detail.hit.zdb_id: 2265211-5
    SSG: 22
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 7
    Online Resource
    Online Resource
    Streptococcus Pneumoniae -Associated Cellulitis in a Two-Month-Old Domestic Shorthair Kitten
    SAGE Publications ; 2006
    In:  Journal of Veterinary Diagnostic Investigation Vol. 18, No. 2 ( 2006-03), p. 221-224
    Details
    In: Journal of Veterinary Diagnostic Investigation, SAGE Publications, Vol. 18, No. 2 ( 2006-03), p. 221-224
    Abstract: An approximately 2-month-old, reproductively intact female Domestic Shorthair kitten was presented to the Mississippi Veterinary Research and Diagnostic Laboratory with a history of possible trauma to the left shoulder region while playing with children, and was found dead the following day. Marked swelling, with subcutaneous edema and hemorrhages, was observed in the left forelimb. Severe pleocellular, but largely suppurative cellulitis, fasciitis, and interstitial myositis with edema were observed microscopically in sections from the affected limb. Massive numbers of gram-positive diplococci also were observed. Other pathologic changes included moderate interstitial pneumonia, mild cholangitis, lymph node hemorrhage, gastrointestinal nematodiasis, mild enteritis, and mild interstitial nephritis. Bacteriologic culture identified Streptococcus pneumoniae as the causative agent, which was confirmed by polymerase chain reaction amplification of the pneumolysin gene from chromosomal DNA of the isolate.
    Type of Medium: Online Resource
    ISSN: 1040-6387 , 1943-4936
    URL: Article
    DOI: 10.1177/104063870601800217
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2006
    detail.hit.zdb_id: 2265211-5
    SSG: 22
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 8
    Online Resource
    Online Resource
    Disarticulation-Associated Femoral Head Separation in Clinically Normal Broilers: Histologic Documentation of Underlying and Predisposing Cartilage Abnormalities
    American Association of Avian Pathologists (AAAP) ; 2019
    In:  Avian Diseases Vol. 63, No. 3 ( 2019-6-11), p. 495-
    Details
    In: Avian Diseases, American Association of Avian Pathologists (AAAP), Vol. 63, No. 3 ( 2019-6-11), p. 495-
    Type of Medium: Online Resource
    ISSN: 0005-2086
    URL: Article
    DOI: 10.1637/19-00090.1
    Language: Unknown
    Publisher: American Association of Avian Pathologists (AAAP)
    Publication Date: 2019
    detail.hit.zdb_id: 2116170-7
    SSG: 12,22
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 9
    Online Resource
    Online Resource
    Immunohistochemical analysis of matrix metalloproteinase-1, -3, and -13 in naturally occurring cartilaginous tumors of dogs
    American Veterinary Medical Association (AVMA) ; 2002
    In:  American Journal of Veterinary Research Vol. 63, No. 9 ( 2002-09-01), p. 1285-1291
    Details
    In: American Journal of Veterinary Research, American Veterinary Medical Association (AVMA), Vol. 63, No. 9 ( 2002-09-01), p. 1285-1291
    Abstract: Objective —To determine immunoreactivity of matrix metalloproteinase (MMP)-1, -3, and -13 in cartilaginous tumors of dogs, correlate expression of MMP with histologic grade of tumors and clinical outcome of dogs, and compare MMP immunoreactivity between chondrosarcomas and chondromas. Sample Population —Formalin-fixed, paraffin-embedded tissues obtained from samples of naturally occurring chondrosarcomas (n = 31) and chondromas (8) of dogs that were submitted to our veterinary medical diagnostic laboratory. Procedure —Histologic sections from each sample were stained with H & E and monoclonal antibody to MMP-1, -3, and -13 by use of an avidin-peroxidase immunohistochemical technique. For each section, histologic grade (I, II, or III) and immunohistochemical expression (0, 1, 2, or 3) were evaluated. Clinical outcome was obtained from medical records or interviews with referring veterinarians and scored as a good outcome, moderate outcome, or poor outcome. Correlations among variables and differences between chondrosarcomas and chondromas were analyzed. Results —Samples from chondrosarcomas had significantly higher immunoreactivity of MMP-1 and -13, compared with immunoreactivity in samples from chondromas. In chondrosarcomas, a significant positive correlation ( r , 0.386) was found between MMP-1 and -13 immunoreactivities, and a significant negative correlation ( r , –0.390) was detected between MMP-3 and -13 immunoreactivities. Conclusion and Clinical Relevance —A significant increase in expression of collagenases (MMP-1 and - 13) in chondrosarcomas, compared with expression in chondromas, suggests that collagenases may play an important role in tumor progression, and possibly metastasis, in chondrosarcomas of dogs. ( Am J Vet Res 2002;63:1285–1291)
    Type of Medium: Online Resource
    ISSN: 0002-9645
    URL: Article
    DOI: 10.2460/ajvr.2002.63.1285
    Language: Unknown
    Publisher: American Veterinary Medical Association (AVMA)
    Publication Date: 2002
    detail.hit.zdb_id: 2056942-7
    SSG: 22
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 10
    Online Resource
    Online Resource
    Mammary duct ectasia in dogs: 51 cases (1992–1999)
    American Veterinary Medical Association (AVMA) ; 2001
    In:  Journal of the American Veterinary Medical Association Vol. 218, No. 8 ( 2001-04-15), p. 1303-1307
    Details
    In: Journal of the American Veterinary Medical Association, American Veterinary Medical Association (AVMA), Vol. 218, No. 8 ( 2001-04-15), p. 1303-1307
    Abstract: Objective —To evaluate the clinical and pathologic characteristics of mammary duct ectasia in dogs. Design —Retrospective study. Animals —51 dogs with mammary duct ectasia. Procedure —Information regarding body condition, history, number and location of affected mammary glands, appearance of lesions, surgical treatment, nonsurgical treatment, and evidence of recurrence or development of mammary neoplasia was obtained from surveys sent to referring veterinarians. Results of information from examination of histologic sections and referring veterinarians were evaluated for all mammary duct ectasia biopsies performed between 1992 and 1999. Results —Duct ectasia was the primary diagnosis in 51 of 1,825 (2.8%) mammary biopsy specimens and comprised 48% of nonneoplastic mammary diseases. Affected dogs were evenly distributed over a range of 1 to 13 years of age, with a mean age at the time of diagnosis of 6.1 ± 3.1 years. All dogs were female (31 sexually intact, 20 spayed); 10 of 26 had whelped. Duct ectasia was described as nodular (26 dogs), cystic (13), and multiglandular (11) and located in caudal (31) more often than cranial (14) or middle glands (10). Ectasia recurred in 3 dogs. One dog had a history of previously excised mammary adenocarcinoma; another subsequently developed mammary carcinoma. Conclusions and Clinical Relevance —Duct ectasia affected mature, sexually intact and spayed female dogs over a wide age range. Certain breeds were affected more commonly than expected. Increased risk for mammary neoplasia was not evident. Duct ectasia should be considered as a cause for mammary enlargement, especially in young dogs or when its cystic nature is evident. Mastectomy is usually curative, and neoplasia should be ruled out in dogs with ectasia. ( J Am Vet Med Assoc 2001;218:1303–1307)
    Type of Medium: Online Resource
    ISSN: 0003-1488
    URL: Article
    DOI: 10.2460/javma.2001.218.1303
    Language: Unknown
    Publisher: American Veterinary Medical Association (AVMA)
    Publication Date: 2001
    detail.hit.zdb_id: 2904887-4
    SSG: 22
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...