In:
Journal of Testing and Evaluation, ASTM International, Vol. 49, No. 6 ( 2021-11-01), p. 4170-4180
Abstract:
Copper oxide nanopellets (CONPs) were produced by hydrothermal strategy. The particles were characterized by distinctive techniques. The synthesized particles were found to have pellet morphology with nonuniform thickness and varying sizes extending between 200 and 550 nm. Studies revealed their microbial nature against both Gram-positive and Gram-negative microscopic organisms, specifically Staphylococcus aureus, Bacillus subtilis, Pseudomonas fluorescens, and Escherichia coli and a plant parasitic pathogen Fusarium oxysporum. Studies demonstrated the antioxidant ability of CONPs at higher concentrations. In this paper, cytotoxicity was measured by blood hemolysis. Anticancer activity of CONPs tested against PC-3, HCT116, A549 and MDA-MB-231 cell lines after 24 hours exhibited IC50 values of 72.27, 144.2, 173.9, and 13.07 μg/mL, respectively. Although these phenomena have been determined in other reports, this report is indeed of significance for CONPs within the particle length of 200–550 nm.
Type of Medium:
Online Resource
ISSN:
0090-3973
,
1945-7553
Language:
English
Publisher:
ASTM International
Publication Date:
2021
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