In:
Ophthalmologica, S. Karger AG, Vol. 237, No. 3 ( 2017), p. 159-166
Abstract:
〈 b 〉 〈 i 〉 Purpose: 〈 /i 〉 〈 /b 〉 To investigate functional and morphological changes in patients with chronic central serous chorioretinopathy after supplementation with antioxidants containing lutein or a placebo. 〈 b 〉 〈 i 〉 Procedures: 〈 /i 〉 〈 /b 〉 One hundred eyes of 100 patients were randomly divided into 2 groups, one taking tablets with lutein plus other antioxidants and the other taking a placebo for 6 months. Best-corrected visual acuity (BCVA) and the subfoveal fluid height on optical coherence tomography were measured. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Seventy-nine patients (37 in the supplementation and 42 in the placebo group) completed the 6-month follow-up. In the supplementation group, mean BCVA showed significant improvement ( 〈 i 〉 p 〈 /i 〉 = 0.003), while there was no significant change in the placebo group ( 〈 i 〉 p 〈 /i 〉 = 0.589). The mean subfoveal fluid height was significantly reduced, by 28.6%, in the supplementation group ( 〈 i 〉 p 〈 /i 〉 = 0.028), in contrast to 3.3% in the placebo group ( 〈 i 〉 p 〈 /i 〉 = 0.898). 〈 b 〉 〈 i 〉 Conclusions: 〈 /i 〉 〈 /b 〉 Antioxidant supplementation significantly reduced subfoveal fluid height. The impacts of antioxidant supplementation on BCVA remain to be elucidated in future studies.
Type of Medium:
Online Resource
ISSN:
0030-3755
,
1423-0267
Language:
English
Publisher:
S. Karger AG
Publication Date:
2017
detail.hit.zdb_id:
1483531-9
Permalink