In:
Materials Science Forum, Trans Tech Publications, Ltd., Vol. 869 ( 2016-8), p. 869-873
Abstract:
A novel chitosan derivative was prepared through direct reaction of pure chitosan with acetylacetone in the absence of a solvent, and it was characterized by elemental analysis, Fourier transform infrared spectrometry (FTIR), and 13 C Nuclear Magnetic Ressonance (NMR) spectroscopy. Moreover, the antibacterial properties of the new biomaterial were tested by the direct contact method against multi-drug resistant strains of Staphylococcus aureus and Escherichia coli. The results from the characterization were consistent with the modification of the chemical structure made. The new derivative showed a better antibacterial activity than raw chitosan against E. coli strains, indicating that incorporation of imine link (Schiff base) enhanced its antibacterial activity against Gram-negative bacterium. On the contrary, this chemical change did not decrease its antibacterial activity against Gram-positive bacterium.
Type of Medium:
Online Resource
ISSN:
1662-9752
DOI:
10.4028/www.scientific.net/MSF.869
DOI:
10.4028/www.scientific.net/MSF.869.869
Language:
Unknown
Publisher:
Trans Tech Publications, Ltd.
Publication Date:
2016
detail.hit.zdb_id:
2047372-2
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