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  • 1
    Online Resource
    Online Resource
    Treatment of Effluent Containing p-Cresol through an Advanced Oxidation Process in a Batch Reactor: Kinetic Optimization
    MDPI AG ; 2023
    In:  Energies Vol. 16, No. 13 ( 2023-06-28), p. 5027-
    Details
    In: Energies, MDPI AG, Vol. 16, No. 13 ( 2023-06-28), p. 5027-
    Abstract: The present research is related to the study of p-cresol oxidation reaction in aqueous phase. Firstly, the conventional advanced oxidation process (AOP) in a lab-scale batch reactor was used, seeking to identify the most impacting process variables and then to propose an optimization approach for ensuring the complete p-cresol degradation and the highest total organic carbon (TOC) conversion. In the AOP with the use of hydrogen peroxide as the oxidizing agent, the oxidation reaction was optimized with the aid of a factorial design, and a maximum TOC conversion of 63% was obtained. The Lumped Kinetic Model (LKM) was used to describe the profile of residual TOC concentration due to chemical species, which were categorized into two groups (refractory and non-refractory compounds). The model was able to satisfactorily describe the profile of the residual fractions of these two classes of organic compounds and allowed estimating the related kinetic constants (k) at two different temperatures, namely (a) 3.19 × 10−1 and 2.82 × 10−3 min−1 for non-refractory and refractory compounds at 80 °C and (b) 4.73 × 10−1 and 5.09 × 10−3 min−1 for the same compound classes at 90 °C, while the activation energy (Ea) of the process was 42.02 and 62.09 kJ mol−1, respectively. The kinetic modeling of organic pollutants oxidation in liquid effluents would allow to perform in situ seawater treatment on vertical reactors installed in offshore platforms and to properly release treated water into the oceans. In this way, ocean contamination caused by the exploration on offshore platforms of oil and natural gas, the main energy sources and vectors in the current world, may be remarkably reduced, thus favoring a more eco-friendly energy production.
    Type of Medium: Online Resource
    ISSN: 1996-1073
    URL: Article
    DOI: 10.3390/en16135027
    Language: English
    Publisher: MDPI AG
    Publication Date: 2023
    detail.hit.zdb_id: 2437446-5
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  • 2
    Online Resource
    Online Resource
    Abstract 392: Impacto of Nifedipine on Polymorphonuclear Cells in Wounds
    Ovid Technologies (Wolters Kluwer Health) ; 2017
    In:  Circulation Research Vol. 121, No. suppl_1 ( 2017-07-21)
    Details
    In: Circulation Research, Ovid Technologies (Wolters Kluwer Health), Vol. 121, No. suppl_1 ( 2017-07-21)
    Abstract: Introduction: Skin wounds are a problem and many occur due to vascular diseases. There is a need for drugs (low cost) that can heal wounds. We aimed to evaluate if the use of nifedipine in wounds is associated with recruitment of polymorphonuclear cells higher than placebo. Hypothesis: Nifedipine stimulates the recruitment of polymorphonuclear in wounds. Methods: We performed 32 wounds in pigs and locally applied placebo or nifedipine (1%, 10% or 20%). Wounds were evaluated macro and microscopically at 6 different moments. A logistic longitudinal model of mixed effects was applied. For this purpose, the response to moderate or marked polymorphonuclear cells was considered as a dependend variable, with the comparison groups (placebo, nifedipine 1%, 10% and 20%) as the explanatory variable. Based on the placebo group, the OR was estimated with its respective confidence interval for the nifedipine groups at the different doses. Value of p 〈 0.05 was considered significant. This study was approved by the animal research ethics committee. Results: The table below shows the proportion of polymorphonuclear cells among the comparison groups over the 6 analyzed moments. Conclusions: Wounds treated with nifedipine had higher recruitment of polymorphonuclear, regardless of the concentration used. This drug has potential for recruitment of this type of cell and may have a beneficial effect on healing.
    Type of Medium: Online Resource
    ISSN: 0009-7330 , 1524-4571
    URL: Article
    DOI: 10.1161/res.121.suppl_1.392
    RVK:
    XA 10000
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2017
    detail.hit.zdb_id: 1467838-X
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  • 3
    Online Resource
    Online Resource
    Abstract 213: Interleukins 17 a and 22: Are There Differences in Blood Concentrations of Patients With or Without Atherosclerosis ?
    Ovid Technologies (Wolters Kluwer Health) ; 2017
    In:  Circulation Research Vol. 121, No. suppl_1 ( 2017-07-21)
    Details
    In: Circulation Research, Ovid Technologies (Wolters Kluwer Health), Vol. 121, No. suppl_1 ( 2017-07-21)
    Abstract: Introduction: The role of the immune and inflammatory pathways in patients with atherosclerosis is important but not complete understood. The objective of this study was to evaluate if patients with coronary atherosclerosis have higher concentrations of interleukins 17 A and 22 when compared to patients without carotid atherosclerosis. Hypothesis: There are higher concentrations of interleukins 17 A and 22 in patients with coronary artery disease than in patients without carotid disease Methods: This is a cross-sectional, prospective, analytical study, conducted from August to December 2015, that enrolled 60 patients. We included 30 patients with stable CAD with coronary stenosis ≥ 50% according to current coronary angiography and 30 patients with chronic infectious parasitic disease without carotid atherosclerosis according to intimal medial thickness. Interleukins (IL) were evaluated in serum of patients. IL concentrations were expressed in pg / ml and the detectable minimum values of interleukins were: 17A = 15.62 pg/ml and 22 = 7.81 pg/ml. Descriptive and analytical statistical analyzes were performed. The Shapiro-Wilk normality test was applied to verify the normality of the data. Statistical tests were used to compare the variables and p-value 〈 0.05 was significant Results: There were 18 men and 12 women in the group of patients with coronary disease and 14 men and 16 patients without carotid disease. The main CAD risk factors (in the group of patients with coronary atherosclerosis) were: Hypertension 63%, Diabetes Mellitus 40%, dyslipidemia 33%, smoking 23%. The serum concentrations of interleukins 17A showed: patients with coronary atherosclerosis = 15.62 pg/ml vs patients without carotid atherosclerosis = 15.62 pg/ml. Serum concentrations of interleukins 22 showed: patients with coronary atherosclerosis = 7.81 pg/ml vs patients without carotid atherosclerosis = 7.81 pg/ml. Conclusions: Interleukin 17 and 22 concentrations were low in both groups of patients and there were no differences between patients with coronary atherosclerosis and no carotid atherosclerosis. Therefore, it is possible that these interleukins measured may not identify who has coronary atherosclerosis and who does not have carotid atherosclerosis.
    Type of Medium: Online Resource
    ISSN: 0009-7330 , 1524-4571
    URL: Article
    DOI: 10.1161/res.121.suppl_1.213
    RVK:
    XA 10000
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2017
    detail.hit.zdb_id: 1467838-X
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  • 4
    Online Resource
    Online Resource
    Avaliação da Toxicidade nas Sementes de Pimentão “Capsicum Annum L.”, Caracterização Físico-Química e Microbiológica em Amostras de Esgoto Doméstico de Recife-PE
    Uniao Atlantica de Pesquisadores ; 2022
    In:  Concilium Vol. 22, No. 2 ( 2022-02-15), p. 414-440
    Details
    In: Concilium, Uniao Atlantica de Pesquisadores, Vol. 22, No. 2 ( 2022-02-15), p. 414-440
    Abstract: A presente pesquisa tem como objetivo avaliar, a partir de uma análise físico-química, microbiológica e testes de fitotoxicidade, as amostras de esgoto domésticos coletadas em alguns edifícios da Região Metropolitana do Recife-PE, após o tratamento desses efluentes em Reator UASB (Upflow Anaerobic Sludge Blanket), a fim de avaliar sua a eficiência de tratamento. Os testes de fitotoxicidade foram realizados nas sementes de Pimentão “Capsicum Annum L.” nesses efluentes, a partir de um planejamento fatorial (22) com dois níveis e dois fatores. Assim, nas referidas amostras foram realizadas as análises de DQO (Demanda Química de Oxigênio), DBO (Demanda Biológica de Oxigênio), T (Temperatura), OG (Óleos e Graxas), pH (potencial Hidrogeniônico), SD60 (Sólidos Sedimentáveis), Coliformes: Totais e Termotolerantes. Os resultados mostraram estar de acordo com a legislação do CONAMA (Conselho Nacional de Meio Ambiente) no tratamento de esgoto com o reator UASB. A toxicidade das amostras na saída do reator UASB tiveram 83,33% de IG (Índice de Germinação) 〈 80% e 16,67% de IG entre 80-120%, o que indica a presença de substâncias que estimulam a germinação das sementes de pimentão.
    Type of Medium: Online Resource
    ISSN: 1414-7327
    URL: Article
    DOI: 10.53660/CLM-152-168
    Language: Unknown
    Publisher: Uniao Atlantica de Pesquisadores
    Publication Date: 2022
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  • 5
    Online Resource
    Online Resource
    Abstract P354: Circulating Interleukin 17 A In Patients With Acute And Chronic Coronary Syndrome
    Ovid Technologies (Wolters Kluwer Health) ; 2021
    In:  Circulation Research Vol. 129, No. Suppl_1 ( 2021-09-03)
    Details
    In: Circulation Research, Ovid Technologies (Wolters Kluwer Health), Vol. 129, No. Suppl_1 ( 2021-09-03)
    Abstract: Introduction: Interleukin L-17 is produced by Th 17 cells and other cells. There is a debate if IL 17 is atherogenic or atheroprotective. The true role of this interleukin during the development and progression of the coronary artery disease is not known. Objective: To evaluate if there are differences between the IL17 A serum levels according to clinical presentation of the coronary artery disease. Methods: This is a cross sectional study which enrolled 101 patients with acute coronary syndrome (ACS), 100 patients with chronic coronary syndrome (CCS) and 100 healthy volunteers. Blood samples were taken from patients ( at admission) and controls to analysis the level of IL17A. Clinical characteristics were collected through questionnaires. This research was approved by ethical committee. Results: Comparisons of the clinical characteristics between patients with ACS and CCS revealed: mean age ( 62 ± 12.4 vs 63.3 ± 9.8, p = 0.4 ), male (63.4% vs 58%, p = 0.4) hypertension (85.1% vs 79%, p = 0.1) , disyipidemia (48% vs 31%, p =0.01), Diabetes Mellitus (47.5% vs 41%, p = 0.3), previous myocardial infarction (57.4% vs 40%, p = 0,01), smoking (29.7% vs 38%, p = 1). The peripheral concentrations of IL17A according to ACS, CCS and controls were: 5.36 ± 8.83 vs 6.69 ± 17.92 vs 6.26 ± 11.13, p = 0.6. Besides, the comparison between ACS and CCS showed: 5.36 ± 8.83 vs 6.69 ± 17.92, p = 0.3. Conclusion: The main finding os this study was that the circulating IL 17 concentrations were similar in patients with ACS, CCS and healthy volunteers). Besides, there was no difference between patients with ACS and CCS. Therefore, our hypothesis is that in patients with ACS and CCS the circulating IL 17 A concentrations are low or undetectable.
    Type of Medium: Online Resource
    ISSN: 0009-7330 , 1524-4571
    URL: Article
    DOI: 10.1161/res.129.suppl_1.P354
    RVK:
    XA 10000
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2021
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  • 6
    Online Resource
    Online Resource
    Abstract 31: Nifedipine Increases Vascular Formations in Skin Wounds
    Ovid Technologies (Wolters Kluwer Health) ; 2017
    In:  Circulation Research Vol. 121, No. suppl_1 ( 2017-07-21)
    Details
    In: Circulation Research, Ovid Technologies (Wolters Kluwer Health), Vol. 121, No. suppl_1 ( 2017-07-21)
    Abstract: Introduction: Loss of skin integrity can result in a wound. Wounds are associated with high cost and disability for patients. Peripheral arterial disease may be the cause of wounds that infect and lead to amputations. Our objective was to evaluate whether the use of nifedipine in wounds is associated with greater amounts of new vascular formations and collagen when compared to placebo. Hypothesis: The new vascular formation in wounds is greater in those treated with nifedipine than in those treated with placebo. Methods: We performed 32 wounds in pigs and locally applied placebo or nifedipine (1%, 10% or 20%). Wounds were evaluated macro and microscopically at 6 different moments. A logistic longitudinal model of mixed effects was applied. For this purpose, the response to moderate or marked polymorphonuclear cells was considered as a dependend variable, with the comparison groups (placebo, nifedipine 1%, 10% and 20%) as the explanatory variable. Based on the placebo group, the OR was estimated with its respective confidence interval for the nifedipine groups at the different doses. Value of p 〈 0.05 was considered significant. This study was approved by the animal research ethics committee. Results: The figure below shows the comparison of new vascular formation and collagen between groups at six different times. Conclusions: The use of nifedipine in wounds was associated with greater vascular formation when compared to placebo. There were differences in the production of collagen between the groups evaluated (in the groups of nifedipine 10% and 20% less amount of collagen). Nifedipine may have a positive impact on the healing of skin wounds.
    Type of Medium: Online Resource
    ISSN: 0009-7330 , 1524-4571
    URL: Article
    DOI: 10.1161/res.121.suppl_1.31
    RVK:
    XA 10000
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2017
    detail.hit.zdb_id: 1467838-X
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  • 7
    Online Resource
    Online Resource
    Unconventional advanced oxidation technique: Evaporation liquid rate and phenolic compounds degradation evaluation and modelling/optimization process with CFD, RSM and ANNs
    Elsevier BV ; 2021
    In:  Fuel Vol. 300 ( 2021-09), p. 120967-
    Details
    In: Fuel, Elsevier BV, Vol. 300 ( 2021-09), p. 120967-
    Type of Medium: Online Resource
    ISSN: 0016-2361
    URL: Article
    DOI: 10.1016/j.fuel.2021.120967
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2021
    detail.hit.zdb_id: 1483656-7
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  • 8
    Online Resource
    Online Resource
    The Issue of the Antiphospholipid Antibody Syndrome
    Elmer Press, Inc. ; 2020
    In:  Journal of Clinical Medicine Research Vol. 12, No. 5 ( 2020), p. 286-292
    Details
    In: Journal of Clinical Medicine Research, Elmer Press, Inc., Vol. 12, No. 5 ( 2020), p. 286-292
    Type of Medium: Online Resource
    ISSN: 1918-3003 , 1918-3011
    URL: Article
    DOI: 10.14740/jocmr4154
    Language: English
    Publisher: Elmer Press, Inc.
    Publication Date: 2020
    detail.hit.zdb_id: 2548987-2
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  • 9
    Online Resource
    Online Resource
    Abstract 108: Interleukins 17 A and 22 in diabetic patients with stable coronary artery disease
    Ovid Technologies (Wolters Kluwer Health) ; 2014
    In:  Circulation Research Vol. 115, No. suppl_1 ( 2014-07-18)
    Details
    In: Circulation Research, Ovid Technologies (Wolters Kluwer Health), Vol. 115, No. suppl_1 ( 2014-07-18)
    Abstract: Introduction: The role of the immune and inflammatory pathways in diabetic patients with coronary artery disease (CAD) is important but not complete understood. The aim of this study was to evaluate concentrations of the interleukins 17 A and 22 in diabetic patients with stable CAD. Hypothesis: Interleukins 17 A and 22 are not increased in diabetic patients with stable CAD. Methods: This is a cross-sectional, prospective, analytical study, conducted from August to December 2012. We included 15 diabetic patients (P) with stable CAD, CCS III or IV, ischemic myocardial scintigraphy, who had not been subjected to any kind of myocardial revascularization and with coronary stenosis ≥ 50% according to current coronary angiography. There were 20 healthy volunteers (C), to take up comparison of concentrations of interleukins (IL). Interleukins were evaluated in serum of patients and after 48 hours of cells in culture with and without stimulus. IL concentrations were expressed in pg / ml. Statistical analysis was performed using the Mann-Whitney or Student t test. P ≤ 0,05 was considered statistically significant. Results: There were 6 men and 9 women in the group of the diabetic patients and 12 men and 8 women in the controls. The age was similar between the groups (61.6 ± 6.7 years vs 57.9 ± 9.4, p = ns). The main CAD risk factors: hypertension 73%, smoking 60%, dyslipidemia 40%, prior myocardial infarction 33%. The comparison between the groups showed: IL 17 A: Serum: P = 3.91 (3.91 -- 3.91 ) vs C = 3.91 (3.91 -- 3.91 ), p = 0.82; culture 48 hours without stimulus: P = 3.91 (3.91 -- 3.91) vs C = 3.91 (3.91 -- 3.91), p = 0.06; culture 48 hours with stimulus: P = 199 (3.91 -- 520) vs C = 154 (3.91 -- 574), p = 0.90. IL 22: Serum: P = 15.63 (15.63 -- 41.09) vs C = 15.63 (15.63 -- 41.09), p = 0.34; culture 48 hours without stimulus: P = 7.81 (7.81 -- 7.81) vs C = 7.81 (7.81 -- 7.81), p = 0.09; culture 48 hours with stimulus: P = 113.79 (7.81 - 248.63) vs C = 322.87 (7.81 - 628.49), p = 0.14. Conclusions: There were no differences in concentrations of IL 17 A and 22, does not matter in serum or cell in culture. In conclusion in diabetic patients with stable CAD the concentrations of interleukins 17 A and 22 were not increased.
    Type of Medium: Online Resource
    ISSN: 0009-7330 , 1524-4571
    URL: Article
    DOI: 10.1161/res.115.suppl_1.108
    RVK:
    XA 10000
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2014
    detail.hit.zdb_id: 1467838-X
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  • 10
    Online Resource
    Online Resource
    Abstract 109: Interleukin 17 A, Coronary Artery Disease And Gender of The Patients
    Ovid Technologies (Wolters Kluwer Health) ; 2014
    In:  Circulation Research Vol. 115, No. suppl_1 ( 2014-07-18)
    Details
    In: Circulation Research, Ovid Technologies (Wolters Kluwer Health), Vol. 115, No. suppl_1 ( 2014-07-18)
    Abstract: Introduction: The effects of interleukins during development of coronary artery disease (CAD) have been studied by researchers and it may help to understand better this disease. The aim of this study was to evaluate if there are differences of concentrations of the IL 17 A between men and women with stable CAD. Hypothesis: There are no differences of concentrations of the IL 17 A according to gender of the patients. Methods: This is a cross-sectional, prospective, analytical study, conducted from August to December 2012. We included 40 patients (24 men (MP) and 16 women (WP) with stable CAD, CCS III or IV, ischemic myocardial scintigraphy, who had not been subjected to any kind of myocardial revascularization and with coronary stenosis ≥ 50% according to current coronary angiography. There were 20 healthy volunteers (12 men (MC) and 8 women (WC), to take up comparison of concentrations of interleukins (IL). Interleukins were evaluated in serum of patients and after 48 hours of cells in culture with and without stimulus. IL concentrations were expressed in pg / ml. Statistical analysis was performed using the Mann-Whitney or Student t test. P ≤ 0,05 was considered statistically significant. Results: The comparison between the groups showed: IL 17 A: Serum: MP = 3.91 (3.91 - 3.91) vs MC = 3.91 (3.91 - 9.28), p = 0.31; culture 48 hours without stimulus: MP = 3.91 (3.91 - 3.91) vs MC = 3.91 (3.91 - 3.91), p = 0.45; culture 48 hours with stimulus: MP = 451.67 (99.02 - 892.58) vs MC = 135 (3.91 -- 285), p = 0.04. IL 17 A: Serum: WP = 3.91 (3.91 - 3.91) vs WC = 3.91 (3.91 -- 6.25), p = 0.90; culture 48 hours without stimulus: WP = 3.91 (3.91 - 3.91) vs WC = 3.91 (3.91 -- 3.91), p = 0.20; culture 48 hours with stimulus: WP = 131.21 (3.91 - 231.97) vs WC = 173.78 (3.91 - 642), p = 0.24. IL 17 A: Serum: MP = 3.91 (3.91 - 3.91) vs WP = 3.91 (3.91 - 3.91), p = 0.17; culture 48 hours without stimulus: MP = 3.91 (3.91 - 3.91) vs WP = 3.91 (3.91 - 3.91), p = 0.47; culture 48 hours with stimulus: MP = 451.67 (99.02 -- 892.58) vs WP = 131.21 (3.91 - 231.97), p = 0.02. Conclusions: There were no differences of concentrations of the IL 17 A between WP and WC. However, MP had higher concentrations of the IL 17 A than MC and WP. Therefore, it is possible that the IL 17 A take part in a pathway which determines different patterns of CAD according to gender.
    Type of Medium: Online Resource
    ISSN: 0009-7330 , 1524-4571
    URL: Article
    DOI: 10.1161/res.115.suppl_1.109
    RVK:
    XA 10000
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2014
    detail.hit.zdb_id: 1467838-X
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