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  • 1
    Online Resource
    Online Resource
    Orthotopic Heart Transplant with Concurrent Supracoronary Ascending Aortic Replacement
    Elsevier BV ; 2022
    In:  Transplantation Proceedings Vol. 54, No. 7 ( 2022-09), p. 1902-1905
    Details
    In: Transplantation Proceedings, Elsevier BV, Vol. 54, No. 7 ( 2022-09), p. 1902-1905
    Type of Medium: Online Resource
    ISSN: 0041-1345
    URL: Article
    DOI: 10.1016/j.transproceed.2022.03.065
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2022
    detail.hit.zdb_id: 82046-5
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  • 2
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    Extracorporeal Membrane Oxygenation during Percutaneous Coronary Intervention in Patients with Coronary Heart Disease
    EDP Sciences ; 2020
    In:  The Journal of ExtraCorporeal Technology Vol. 52, No. 3 ( 2020-9), p. 196-202
    Details
    In: The Journal of ExtraCorporeal Technology, EDP Sciences, Vol. 52, No. 3 ( 2020-9), p. 196-202
    Abstract: Extracorporeal membrane oxygenation (ECMO) has become an effective method in the treatment of adults and children with severe cardiac and pulmonary dysfunction that is resistant to conventional therapy. The aim of this article was to summarize an experience of ECMO usage for cardiac dysfunction, which develops in patients with coronary heart disease (CHD) during percutaneous transluminal coronary angioplasty. The study comprised a retrospective, single-center analysis of 23 patients with CHD (19 men and four women, average age 65.7 ± 12.3 years), who undertook the ECMO technique during percutaneous transluminal coronary angioplasty. A total of 13 (56.52%) patients died directly in the hospital, or 30 days after a discharge. Independent predictors of fatal outcomes were diabetes mellitus (odds ratio [OR] = 17.58; 95% confidence interval [CI] = 6.47–47.48; p = .00125), chronic renal failure (CRF) (OR = 20.81; 95% CI = 5.95–72.21; p = .00014), and damage to the right coronary artery (RCA) (OR = 25.51; 95% CI = 8.27–79.12; p = .00013). For deceased patients, the “no reflow” phenomenon was indicated in a larger percentage of cases (23.1% in the group of deceased, vs. 10% in the group of survivors). A routine connection to ECMO before the occurrence of cardiac events was significantly more often used in the group of survived patients (90% of cases) than in the deceased ( p = .0000001). Diabetes mellitus, CRF, and damage to the RCA were independent predictors of mortality during percutaneous transluminal coronary angioplasty in patients with CHD. The routine use of ECMO in high-risk patients with percutaneous transluminal coronary angioplasty was a positive prognostic factor of patient survival.
    Type of Medium: Online Resource
    ISSN: 0022-1058 , 2969-8960
    URL: Article
    DOI: 10.1051/ject/202052196
    Language: English
    Publisher: EDP Sciences
    Publication Date: 2020
    detail.hit.zdb_id: 2465229-5
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  • 3
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    Effects of multimodal low-opioid anesthesia protocol during on-pump coronary artery bypass grafting: a prospective cohort study
    Springer Science and Business Media LLC ; 2023
    In:  Journal of Cardiothoracic Surgery Vol. 18, No. 1 ( 2023-10-06)
    Details
    In: Journal of Cardiothoracic Surgery, Springer Science and Business Media LLC, Vol. 18, No. 1 ( 2023-10-06)
    Abstract: The most favorable anesthesia protocol during on-pump coronary artery bypass grafting (CABG) in patients with coronary heart disease remains unclear, despite previous publications regarding the interaction between anesthesia protocol and postoperative complications. The aim of the study was to compare the effect of a multimodal low-opioid anesthesia protocol (MLOP) on early postoperative complications during on-pump CABG. Methods A single-center prospective cohort study including 120 patients undergoing on-pump CABG aged 18 to 65 years, divided into two groups according to undergoing MLOP or routine-opioid anesthesia protocol (ROP). The analyzed parameters were plasma IL-6 levels, complications, duration of mechanical ventilation, length of intensive care unit stay, and hospitalization. Results In the MLOP group, the levels of IL-6 at the end of the surgery were 25.6% significantly lower compared to the ROP group (33.4 ± 9.4 vs. 44.9 ± 15.9, p  〈  0.0001), the duration of mechanical ventilation was significantly shorter (2.0 (2.0; 3.0) h vs. 4.0 (3.0; 5.0) h, p  〈  0.001), the incidence of low cardiac output syndrome was almost two and half times lower (7 (11.7%) vs. 16 (26.7%), p = 0.037), and also the incidence of postoperative atrial fibrillation was significantly lower (9 (15.0%) vs. 19 (31.7%), p = 0.031). Conclusion Our study confirms that using MLOP was characterized by significantly lower levels of IL-6 at the end of surgery and a lower incidence of low cardiac output syndrome and postoperative atrial fibrillation than ROP. Trial registration The study is registered in clinicaltrials.gov №NCT05514652.
    Type of Medium: Online Resource
    ISSN: 1749-8090
    URL: Article
    DOI: 10.1186/s13019-023-02395-y
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2227224-0
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  • 4
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    INFLUENCE OF ACUTE CORONARY SYNDROME ON INTRAOPERATIVE DYNAMICS OF IL-6 DURING CORONARY REVASCULARIZATION
    OU Scientific Route ; 2020
    In:  EUREKA: Health Sciences Vol. 5 ( 2020-9-30), p. 16-21
    Details
    In: EUREKA: Health Sciences, OU Scientific Route, Vol. 5 ( 2020-9-30), p. 16-21
    Abstract: Percutaneous x-ray endovascular angioplasty is one of the most modern methods of treatment of severe forms of cardiovascular diseases. In the pathogenesis of acute coronary syndrome, a special place is occupied by the proinflammatory reaction of the body. The main “secondary” marker is interlekin-6. The peak of its production occurs on the first day of damage and correlates with its size. The aim of the study. To investigate the dynamics of interleukin-6 level in the perioperative period of coronary revascularization, depending on the presence of acute coronary syndrome. Materials and methods. This study included 68 patients with coronary artery disease. The patients were divided into three study groups. Group 1 and 2 patients were diagnosed with ACS, and they underwent emergency stenting of coronary vessels in order to recanalize occlusion of the coronary arteries. 3rd group patients did not have ACS and they were recanalized as planned. Results. Analyzing the results of the study, we found that the highest obtained values of IL-6 were in group 1 in comparison with the group of patients who were surgically treated as planned and after stent placement, the interleukin values were 24.8 % higher in group 1 than in group 2 and almost 4 times higher in group 3 (p 〈 0.001). When comparing groups with acute coronary syndrome, interleukin-6 indices were significantly higher by 47.4 % before surgery in group 3 and by 24.9 % after stent placement, which once again confirms the severity of patients with acute myocardial infarction. Conclusions. Intraoperatively proinflammatory interlekin-6 after coronary artery stenting tends to increase in groups with acute coronary syndrome, while in the group with stable angina, these indicators are significantly higher by 22.8 % (p 〈 0.001). The dynamics of Il-6 levels clearly correlates with the severity of the patient's condition and increases in the presence of acute coronary syndrome, especially in the presence of acute myocardial infarction.
    Type of Medium: Online Resource
    ISSN: 2504-5679 , 2504-5660
    URL: Journal
    URL: Article
    DOI: 10.21303/2504-5679
    DOI: 10.21303/2504-5679.2020.001413
    Language: English
    Publisher: OU Scientific Route
    Publication Date: 2020
    detail.hit.zdb_id: 3009626-1
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  • 5
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    Online Resource
    Being perfusionist during the war – cardiac surgery under missile strikes
    SAGE Publications ; 2023
    In:  Perfusion Vol. 38, No. 7 ( 2023-10), p. 1536-1538
    Details
    In: Perfusion, SAGE Publications, Vol. 38, No. 7 ( 2023-10), p. 1536-1538
    Type of Medium: Online Resource
    ISSN: 0267-6591 , 1477-111X
    URL: Article
    DOI: 10.1177/02676591221118689
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2029611-3
    detail.hit.zdb_id: 645038-6
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  • 6
    Online Resource
    Online Resource
    Perceptions of gender equity in departmental leadership, research opportunities, and clinical work attitudes: an international survey of 11 781 anaesthesiologists
    Elsevier BV ; 2020
    In:  British Journal of Anaesthesia Vol. 124, No. 3 ( 2020-03), p. e160-e170
    Details
    In: British Journal of Anaesthesia, Elsevier BV, Vol. 124, No. 3 ( 2020-03), p. e160-e170
    Type of Medium: Online Resource
    ISSN: 0007-0912
    URL: Article
    DOI: 10.1016/j.bja.2019.12.022
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2020
    detail.hit.zdb_id: 80074-0
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  • 7
    Online Resource
    Online Resource
    Influence of low-opioid anesthesia in cardiac surgery on dynamics of pro-inflammatory interleukin-6
    Termedia Sp. z.o.o. ; 2020
    In:  Polish Journal of Cardio-Thoracic Surgery Vol. 17, No. 1 ( 2020), p. 39-43
    Details
    In: Polish Journal of Cardio-Thoracic Surgery, Termedia Sp. z.o.o., Vol. 17, No. 1 ( 2020), p. 39-43
    Type of Medium: Online Resource
    ISSN: 1731-5530
    URL: Article
    DOI: 10.5114/kitp.2020.94190
    Language: Unknown
    Publisher: Termedia Sp. z.o.o.
    Publication Date: 2020
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  • 8
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    Modern approaches to the correction of hemodynamic disorders in patients with severe combined trauma
    Interdisciplinar Academy of Pain Medicine ; 2020
    In:  Perioperaciina Medicina Vol. 3, No. 1 ( 2020-06-01), p. 21-26
    Details
    In: Perioperaciina Medicina, Interdisciplinar Academy of Pain Medicine, Vol. 3, No. 1 ( 2020-06-01), p. 21-26
    Abstract: Background. The choice of a rational program of infusion therapy for severe trauma remains an urgent problem. Crystalloid solutions are used as the main infusion media, but data on the effect of balanced multicomponent solutions on the hemodynamic profile in patients with severe trauma in the literature are almost absent. The aim: to investigate the possibility of correction of hemodynamic disorders in patients with severe combined trauma with the use of a modern multicomponent drug based on a 6% solution of sorbitol (reosorbilact). Material and methods: a total of 60 patients with severe combined trauma and the clinic of degree I–II traumatic shock aged 18 to 46 years were examined. Patients were divided into two groups: 1st group (n = 30) – patients who included in the standard complex of intensive care (IС) reosorbilact at a dose of 8–10 ml/kg body weight; 2nd group (n = 30) – patients who underwent a standard IС complex. Results: administration of reosorbilact resulted in a decrease in extracellular fluid volume, an increase in BCC and a transition from hypokinetic to eukinetic circulation within 3 hours of infusion and persisted for up to 6 hours after infusion (p 〈 0.01). The introduction of adrenomimetics were required: before the study in groups 1 and 2 – 7 (23.3 %) and 6 (20.0 %) patients, after 6 hours – respectively 1 (3.3 %) and 4 (13.3 %), and one day after the introduction of reosorbilact no patient required the introduction of adrenomimetics, whereas in group 2 such patients were 3 (10.0 %, p 〈 0.05). Conclusions. The use of balanced multicomponent solutions based on sorbitol is accompanied by a change in the hypokinetic type of blood circulation to eukinetic, lack of interhydration hyperhydration, rapid stabilization of hemodynamic parameters and reduced need for adrenomimetic support. Conflict of interest: absent
    Type of Medium: Online Resource
    ISSN: 2617-2925 , 2616-339X
    URL: Article
    DOI: 10.31636/prmd.v3i1.4
    Language: Unknown
    Publisher: Interdisciplinar Academy of Pain Medicine
    Publication Date: 2020
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  • 9
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    CLINICAL CASE OF SUCCESSFUL MANAGEMENT OF ACUTE MYOCARDIAL INFARCTION DURING PREGNANCY
    ALUNA ; 2019
    In:  Wiadomości Lekarskie Vol. 72, No. 2 ( 2019-2), p. 298-301
    Details
    In: Wiadomości Lekarskie, ALUNA, Vol. 72, No. 2 ( 2019-2), p. 298-301
    Abstract: Introduction: There have recently been increasingly frequent reports of myocardial infarction (MI) in pregnancy and in the postpartum period. Pertinent and timely treatment affect maternal and fetal morbidity and mortality. Clinical case: We are reporting about a 42 years old woman at the 19th week of gestation, with complains of chest pain with irradiation into the left arm, and shortness of breath. It was known from the history of present illness, that at the time of the event ventricular fibrillation was recorded and resuscitation measures with cardioversion were performed. Subsequently, after an additional examination in the hospital, a diagnosis of MI has been determined. Coronary angiography with cardiac ventriculography (CVG) has been performed and stenosis of left anterior descending coronary artery (LAD) and right coronary artery (RCA) detected. A revascularization with the insertion of the bare-metal stent system has performed and double antiplatelet therapy prescribed. At 37 weeks of gestation, the patient gave birth to a healthy child by caesarean section. Conclusions: This clinical case illustrates the importance of minimizing the time to hospitalization of a pregnant woman with a MI to a specialized center for timely and complete diagnostic measures, which, in turn, allow to properly choose the tactics of patient management. Timely revascularization and properly selected anticoagulation are the key factors of the successful management in this category of patients.
    Type of Medium: Online Resource
    ISSN: 0043-5147
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.36740/WLek201902
    DOI: 10.36740/WiadLek
    DOI: 10.36740/WLek201902130
    Language: English
    Publisher: ALUNA
    Publication Date: 2019
    detail.hit.zdb_id: 414731-5
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  • 10
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    Evaluation of the Effectiveness of Immunosorbent-Based Hemosorption in Comprehensive Conservative Therapy of End-Stage Heart Failure Patients
    Professional Edition Eastern Europe ; 2022
    In:  Ukrainian Journal of Cardiovascular Surgery Vol. 30, No. 1 (46) ( 2022-03-23), p. 43-48
    Details
    In: Ukrainian Journal of Cardiovascular Surgery, Professional Edition Eastern Europe, Vol. 30, No. 1 (46) ( 2022-03-23), p. 43-48
    Abstract: Background. Heart failure is the leading cause of death among all cardiovascular diseases. The five-year survival rate in such patients is 50%. In most cases, heart transplantation is the treatment of choice in these patients. However, its use is limited by severe and progressive donor organ deficiency. The aim. To study the effectiveness of immunosorbent-based hemosorption in comprehensive conservative treatment of patients with end-stage heart failure. Materials and methods. A retrospective analysis of the results of treatment in 59 patients 90% men, 10% women; mean age 41.3 ± 12.4 years; NYHA IIB-III, baseline left ventricular ejection fraction 21.1 ± 4.66%, left ventricular endsystolic volume 206.87 ± 84.1 ml, left ventricular end-diastolic volume 264.4 ± 86.02 ml) hospitalized for end-stage heart failure was performed. Conservative therapy was carried out following international guidelines and was supplemented by a course of 2-4 hemosorption procedures for which hemosorbent granulated deliganding was used. The Student’s t-test was used to analyze the data. Results. The clinical condition of all patients improved after the performed hemosorption procedures by at least one NYHA class. The brain natriuretic peptide level decreased from 1281.17±165.33 pg/ml to 859.48±113.38 pg/ml (p 〈 0.05). Left ventricular ejection fraction increased by 10.77±4.3% (to 29.36 ± 6.27%) (p 〈 0.01), and after 12 months it was 34 ± 2.59% (p 〈 0.05). Left ventricular end-systolic volume decreased by 68.75±43.56 ml (to 137.77 ± 33.21 ml), left ventricular end-diastolic volume decreased by 41.38±31.48 ml (to 238.04 ± 82.1 ml) (p 〈 0.05). Conclusions. The use of hemosorption with hemosorbent granulated deliganding, against the background of conservative treatment of end-stage heart failure, improves the contractile function of the heart and general clinical condition of patients.
    Type of Medium: Online Resource
    ISSN: 2664-5971 , 2664-5963
    URL: Article
    DOI: 10.30702/ujcvs/22.30(01)/DL012-4348
    Language: Unknown
    Publisher: Professional Edition Eastern Europe
    Publication Date: 2022
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