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  • 1
    Online Resource
    Online Resource
    National Library of Serbia ; 2021
    In:  Thermal Science Vol. 25, No. 3 Part A ( 2021), p. 1879-1889
    In: Thermal Science, National Library of Serbia, Vol. 25, No. 3 Part A ( 2021), p. 1879-1889
    Abstract: Bottom ash samples were collected from four lignite power plants of Greece. Granulometric analysis was executed and after homogenization four distinct fractions (〉1.25, 0.63-1.25, 0.18-0.63, 〈0.18 mm) were obtained. The samples were analysed by X-ray diffraction and energy dispersive system, while thermo-gravimetric and stereomicroscope viewing were applied for the coarse fractions. Furthermore, proximate analysis (moisture, ash, volatiles, fixed carbon) was un-dertaken and loss on ignition and calorific values were determined. The particle size distribution revealed that bottom ash satisfies the gradation criteria for concrete and geotechnical applications. The mineral composition included mainly amorphous matter, quartz, plagioclase, calcite and gehlenite and minor amounts of pyroxene, portlandite, hematite, micas, etc. The chemical analysis showed Si, Ca, Al, Mg, Fe, S as major and Ti and K as minor chemical elements, indicating high slagging, and fouling potential within the thermal chambers. Based on the chemistry and mineralogy of the bottom ash samples, a potential utilization in concrete manufacturing is discussed, taking into account certain limitations. Based on loss on ignition, proximate analysis, calorific values and thermogravi-metric profiles of the coarse fractions (〉1.25 mm), certain differences in the characteristics of the bottom ash of the younger and the three older power plants were observed. High amounts of unburnt carbon were determined in the coarse fraction (〉1.25 mm) of all plants except the younger one, indicating a problematic combustion within the chambers and a potential of reburning these coarse material in a waste to energy application.
    Type of Medium: Online Resource
    ISSN: 0354-9836 , 2334-7163
    Language: English
    Publisher: National Library of Serbia
    Publication Date: 2021
    detail.hit.zdb_id: 2241319-4
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  • 2
    In: World Neurosurgery, Elsevier BV, Vol. 117 ( 2018-09), p. e228-e237
    Type of Medium: Online Resource
    ISSN: 1878-8750
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2018
    detail.hit.zdb_id: 2530041-6
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  • 3
    In: Journal of Human Hypertension, Springer Science and Business Media LLC, Vol. 37, No. 6 ( 2022-07-14), p. 449-454
    Abstract: The HYPEDIA study aimed at evaluating the implementation of the 2018 European guidelines for treating hypertension in primary care. A nationwide prospective non-interventional cross-sectional study was performed in consecutive untreated or treated hypertensives recruited mainly in primary care in Greece. Participants’ characteristics, office blood pressure (BP) (triplicate automated measurements, Microlife BPA3 PC) and treatment changes were recorded on a cloud platform. A total of 3,122 patients (mean age 64 ± 12.5 [SD] years, 52% males) were assessed by 181 doctors and 3 hospital centers. In 772 untreated hypertensives (25%), drug treatment was initiated in the majority, with monotherapy in 53.4%, two-drug combination in 36.3%, and three drugs in 10.3%. Angiotensin receptor blocker (ARB) monotherapy was initiated in 30%, ARB/calcium channel blocker (CCB) 20%, ARB/thiazide 8%, angiotensin converting enzyme inhibitor (ACEi)-based 19%. Of the combinations used, 97% were in single-pill. Among 977 treated hypertensives aged 〈 65 years, 79% had BP ≥ 130/80 mmHg (systolic and/or diastolic), whereas among 1,373 aged ≥65 years, 66% had BP ≥ 140/80 mmHg. ARBs were used in 69% of treated hypertensives, CCBs 47%, ACEis 19%, diuretics 39%, beta-blockers 19%. Treatment modification was decided in 53% of treated hypertensives aged 〈 65 years with BP ≥ 130/80 mmHg and in 62% of those ≥65 years with BP ≥ 140/80 mmHg. Renin-angiotensin system blocker-based therapy constitutes the basis of antihypertensive drug treatment in most patients in primary care, with wide use of single-pill combinations. In almost half of treated uncontrolled hypertensives, treatment was not intensified, suggesting suboptimal implementation of the guidelines and possible physician inertia.
    Type of Medium: Online Resource
    ISSN: 1476-5527
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2006792-6
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  • 4
    In: International Journal of Spine Surgery, International Journal of Spine Surgery, Vol. 16, No. 1 ( 2022-02), p. 33-41
    Type of Medium: Online Resource
    ISSN: 2211-4599
    Language: English
    Publisher: International Journal of Spine Surgery
    Publication Date: 2022
    detail.hit.zdb_id: 2660509-0
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  • 5
    In: BMC Research Notes, Springer Science and Business Media LLC, Vol. 15, No. 1 ( 2022-12-20)
    Abstract: to assess the effects of cilostazol on pain-free walking distance in PAD patients with IC at 3 and 6 months in a real world, prospective, observational study. We included 1015 PAD patients presenting with IC (71.3% men, 93.5% white, mean age 69.2 ± 8.7 years). Patients were followed up for 6 months by their physicians. Results Cilostazol significantly increased pain-free walking distance by a median of 285 and 387 m at 3 and 6 months, respectively (p  〈  0.01 for all comparisons). This effect was significant for patients 50–74 years (but not for those aged ≥ 75 years) and independent of smoking status, changes in physical activity, comorbidities and concomitant medication for PAD (i.e., acetylsalicylic acid and clopidogrel). Furthermore, significant reductions were observed in systolic (from 139 ± 16 to 133 ± 14 mmHg; p  〈  0.001) and diastolic blood pressure (from 84 ± 9 mmHg to 80 ± 10 mmHg; p  〈  0.001). Smoking cessation and increased physical activity were reported by the majority of participants. In conclusion, cilostazol was shown to safely decrease pain symptoms and improve pain-free walking in PAD patients with IC in a real world setting. Benefits also occurred in terms of BP and lifestyle changes.
    Type of Medium: Online Resource
    ISSN: 1756-0500
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2413336-X
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  • 6
    Online Resource
    Online Resource
    Informa UK Limited ; 2013
    In:  Conservation and Management of Archaeological Sites Vol. 15, No. 1 ( 2013-02), p. 121-134
    In: Conservation and Management of Archaeological Sites, Informa UK Limited, Vol. 15, No. 1 ( 2013-02), p. 121-134
    Type of Medium: Online Resource
    ISSN: 1350-5033 , 1753-5522
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2013
    detail.hit.zdb_id: 2431759-7
    SSG: 6,14
    SSG: 6,11
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  • 7
    In: Orthopaedic Surgery, Wiley, Vol. 14, No. 8 ( 2022-08), p. 1607-1614
    Abstract: To assess which radiological alignment parameters are associated with a satisfactory long‐term clinical outcome after performing lumbar spinal fusion for treating degenerative spondylolisthesis. Methods This single‐center prospective study assessed the relation between radiological alignment parameters measured on standing lateral lumbar spine radiographs and the patient‐reported outcome using four different questionnaires (COMI, EQ‐5D, ODI and VAS) as primary outcome measures (level of evidence: II). The following spinopelvic alignment parameters were used: gliding angle, sacral inclination, anterior displacement, sagittal rotation, lumbar lordosis, sacral slope, pelvic tilt and pelvic incidence. Furthermore, the length of stay and perioperative complications were documented. Only cases from 2013 to 2015 of low‐grade degenerative lumbar spondylolisthesis (Meyerding grades I and II) were considered. The patients underwent open posterior lumbar fusion surgery by pedicle screw instrumentation and cage insertion. The operative technique was either a posterior lumbar interbody fusion (PLIF) or a transforaminal lumbar interbody fusion (TLIF) performed by three different senior orthopedic surgeons. Exclusion criteria were spine fractures, minimally invasive techniques, underlying malignant diseases or acute infections, previous or multisegmental spine surgery as well as preoperative neurologic impairment. Of 89 initially contacted patients, 17 patients were included for data analysis (11 males, six females). Results The data of 17 patients after mono‐ or bisegmental lumbar fusion surgery to treat low‐grade lumbar spondylolisthesis and with a follow‐up time of least 72 months were analyzed. The mean age was 66.7 ± 11.3 years. In terms of complications two dural tears and one intraoperative bleeding occurred. The average body mass index (BMI) was 27.6 ± 4.4 kg/m 2 and the average inpatient length of stay was 12.9 ± 3.8 days (range: 8–21). The long‐term clinical outcome correlated significantly with the change of the pelvic tilt ( r s  = −0.515, P   〈  0.05) and the sagittal rotation ( r s  = −0.545, P   〈  0.05). The sacral slope was significantly associated with the sacral inclination ( r s  = 0.637, P   〈  0.01) and the pelvic incidence ( r s  = 0.500, P   〈  0.05). In addition, the pelvic incidence showed a significant correlation with the pelvic tilt ( r s  = 0.709, P   〈  0.01). The change of the different clinical scores over time also correlated significantly between the different questionnaires. Conclusions The surgical modification of the pelvic tilt and the sagittal rotation are the two radiological alignment parameters that can most accurately predict the long‐term clinical outcome after lumbar interbody fusion surgery.
    Type of Medium: Online Resource
    ISSN: 1757-7853 , 1757-7861
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2483883-4
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  • 8
    In: Asian Spine Journal, Asian Spine Journal (ASJ), Vol. 15, No. 5 ( 2021-10-31), p. 701-707
    Abstract: The physiopathogenesis of adolescent idiopathic scoliosis remains unknown. However, a multifactorial pathogenesis is being assumed. Besides biomechanical, biochemical, and genetic factors, some studies have focused on congenital or acquired abnormalities in the vestibular organ with consecutive development of scoliosis. This study aims to analyze a possible correlation between any vestibular organ congenital or acquired pathologies and scoliosis based on the current literature. Therefore, we conducted a literature search in three databases, with search terms such as “scoliosis,” “organ of balance,” “idiopathic scoliosis,” “vestibular organ,” “spine,” and “balance.” Fifteen studies were selected and used for research. The relationship between scoliosis and vestibular organ abnormalities was recorded from all included works. Seven studies demonstrated a direct correlation between vestibular organ anatomical abnormalities and the form of the scoliotic spine. Another study confirmed the influence of the pathology of the vestibular organ on scoliosis but questioned whether it had an impact on the formation or the progression of the curvature. Others demonstrated a temporal overlap of the embryonic development of the vestibular organ and the beginning of pre-scoliotic characteristics, but their relationship remained questionable. In three studies, the correlation remained unclear, and any context has been denied. It seems unlikely that an isolated vestibular disorder can trigger structural scoliosis. However, the vestibular system pathologies may certainly occur in the multifactorial genesis of idiopathic scoliosis. Whether the correlation refers to the expression or the progression of scoliosis or may even have an influence on both remains unclear. New treatment options could be derived from these findings with a positive influence on the course of the deformity.
    Type of Medium: Online Resource
    ISSN: 1976-1902 , 1976-7846
    Language: English
    Publisher: Asian Spine Journal (ASJ)
    Publication Date: 2021
    detail.hit.zdb_id: 2502303-2
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  • 9
    In: Journal of Orthopaedics, Elsevier BV, Vol. 37 ( 2023-03), p. 1-4
    Type of Medium: Online Resource
    ISSN: 0972-978X
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
    detail.hit.zdb_id: 2240839-3
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  • 10
    In: Clinical Orthopaedics & Related Research, Ovid Technologies (Wolters Kluwer Health), Vol. 481, No. 8 ( 2023-08), p. 1610-1619
    Abstract: Spinal fusion is a well-established procedure in the treatment of degenerative spinal diseases. Previous research shows that the use of this operative treatment has been growing in recent decades in industrialized countries and has become one of the most cost-intensive surgical procedures. It seems that in some countries such as Germany—with its large, industrialized, European population—this increase is mainly driven by demographic changes with low fertility rates, increasing life expectancy, and an aging population. Based on current projections, however, Germany faces a population trend that many other countries are likely to follow within a few decades. An increasingly shrinking and aging working population may eventually put the healthcare system under enormous pressure, with greater demands for spinal fusions and associated higher costs. Thus, we aimed to provide reliable projections regarding the future demand for posterior spinal fusion procedures including age- and gender-related trends up to 2060, which will be necessary for future resource planning and possible improvements in actual treatment strategies. Questions/purposes (1) How is the use of posterior spinal fusions in Germany expected to change from 2019 through 2060, if currents trends continue? (2) How is the use of posterior spinal fusions in Germany expected to change depending on patients’ age and gender during this time period? Methods Comprehensive nationwide data provided by the Federal Statistical Office, the official institution for documenting all data on operations and procedures performed in Germany, were used to quantify posterior spinal fusion rates as a function of calendar year, age, and gender. Because there is a lack of evidence regarding future trends in the use of posterior spinal fusions, an autoregressive integrated moving average model on historical procedure rates from 2005 to 2019 in relation to official population projections from 2020 to 2060 was chosen to forecast future absolute numbers and incidence rates of this procedure in Germany. Long-term forecasting is more prone to unexpected disruptions than forecasting over short-term periods; however, longer spans facilitate estimates of how trends may challenge future healthcare systems if those trends continue, and thus are useful for research and planning. Results The incidence rate of posterior spinal fusion was projected to increase by approximately 83% (95% CI 28% to 139%) to 102% per 100,000 inhabitants (95% CI 71% to 133%) in 2060, with a 1.3-fold higher rate of women undergoing surgery in terms of absolute numbers. The highest increase identified by the model occurred in patients 75 years and older with 38,974 (95% CI 27,294 to 50,653) posterior spinal fusions in 2060, compared with 14,657 in 2019. This trend applied for both women and men, with a 246% (95% CI 138% to 355%) increase in the total number of posterior spinal fusions for women 75 years and older and a 296% (95% CI 222% to 370%) increase for men 75 years and older. At the same time, posterior spinal fusions in all age groups younger than 55 years were projected to follow a constant or even negative trend up to 2060. Conclusion Our findings suggest that increasing use of posterior spinal fusion, particularly in patients 75 years and older, will challenge healthcare systems worldwide if current trends persist. This study may serve as a model for many other industrialized countries facing similar demographic and procedure-specific developments in the future. This emphasizes the need to focus on frailty research as well as appropriate financial and human resource management. Effective perioperative medical management, multidisciplinary treatment, and interinstitutional protocols are warranted, especially in older patients as we attempt to manage these trends in the future. Level of Evidence Level III, economic and decision analysis.
    Type of Medium: Online Resource
    ISSN: 0009-921X , 1528-1132
    RVK:
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2023
    detail.hit.zdb_id: 2018318-5
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