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  • 1
    Online Resource
    Online Resource
    Annual report SWEDEHEART 2012
    Informa UK Limited ; 2014
    In:  Scandinavian Cardiovascular Journal Vol. 48, No. sup63 ( 2014-08), p. 2-133
    Details
    In: Scandinavian Cardiovascular Journal, Informa UK Limited, Vol. 48, No. sup63 ( 2014-08), p. 2-133
    Type of Medium: Online Resource
    ISSN: 1401-7431 , 1651-2006
    URL: Article
    DOI: 10.3109/14017431.2014.931554
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2014
    detail.hit.zdb_id: 1497073-9
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  • 2
    Online Resource
    Online Resource
    Head movement compensation and multi-modal event detection in eye-tracking data for unconstrained head movements
    Elsevier BV ; 2016
    In:  Journal of Neuroscience Methods Vol. 274 ( 2016-12), p. 13-26
    Details
    In: Journal of Neuroscience Methods, Elsevier BV, Vol. 274 ( 2016-12), p. 13-26
    Type of Medium: Online Resource
    ISSN: 0165-0270
    URL: Article
    DOI: 10.1016/j.jneumeth.2016.09.005
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2016
    detail.hit.zdb_id: 1500499-5
    SSG: 12
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  • 3
    Online Resource
    Online Resource
    Systems of variational inequalities in the context of optimal switching problems and operators of Kolmogorov type
    Springer Science and Business Media LLC ; 2014
    In:  Annali di Matematica Pura ed Applicata (1923 -) Vol. 193, No. 4 ( 2014-8), p. 1213-1247
    Details
    In: Annali di Matematica Pura ed Applicata (1923 -), Springer Science and Business Media LLC, Vol. 193, No. 4 ( 2014-8), p. 1213-1247
    Type of Medium: Online Resource
    ISSN: 0373-3114 , 1618-1891
    URL: Article
    DOI: 10.1007/s10231-013-0325-y
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2014
    detail.hit.zdb_id: 2049996-6
    SSG: 17,1
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  • 4
    Online Resource
    Online Resource
    Estimated glucose disposal rate is associated with retinopathy and kidney disease in young people with type 1 diabetes: a nationwide observational study
    Springer Science and Business Media LLC ; 2023
    In:  Cardiovascular Diabetology Vol. 22, No. 1 ( 2023-03-19)
    Details
    In: Cardiovascular Diabetology, Springer Science and Business Media LLC, Vol. 22, No. 1 ( 2023-03-19)
    Abstract: The aim of this study was to investigate the association between estimated glucose disposal rate (eGDR), a proxy for insulin resistance, and retinopathy or kidney disease, i.e. micro-, or macroalbuminuria, in young individuals with type 1 diabetes (T1D). Material and Methods Using data from the Swedish pediatric registry for diabetes (SweDiabKids) and the registry for adults (NDR), all individuals with T1D with a duration of diabetes of less than 10 years between 1998 and 2017 were included. We calculated the crude incidence rates with 95% confidence intervals (CIs) and used multivariable Cox regression to estimate crude and adjusted hazard ratios (HRs) for two cohorts: retinopathy cohort or kidney disease cohort, stratified by eGDR categories: 〈  4, 4 to 5.99, 6 to 7.99, and ≥ 8 mg/kg/min (reference). Results A total of 22 146 (10 289 retinopathy cohort, and 11 857 kidney disease cohort with an overlapping of 9575) children and adults with T1D (median age 21 years, female 42% and diabetes duration of 6 and 7 years, respectively for the cohorts) were studied. During a median follow-up of 4.8 years (IQR 2.6–7.7) there were 5040 (24.7%), 1909 (48.1%), 504 (52.3%) and 179 (57.6%) events for retinopathy in individuals with an eGDR ≥ 8, 7.99 to 6, 5.99 to 4, and 〈  4 mg/kg/min, respectively. Corresponding numbers for kidney disease was 1321 (6.5%), 526 (13.3%), 255 (26.8%) and 145 (46.6%). After multiple adjustments for different covariates, individuals with an eGDR 7.99 to 6, 5.99 to 4 and 〈  4 mg/kg/min, had an increased risk of retinopathy compared to those with an eGDR ≥ 8 mg/kg/min (adjusted HRs, 95% CIs) 1.29 (1.20 to 1.40); 1.50 (1.31 to 1.71) and 1.74 (1.41 to 2.14). Corresponding numbers for kidney disease was (adjusted HRs, 95% CIs) 1.30 (1.11 to 1.52); 1.58 (1.25 to 1.99) and 1.33 (0.95 to 1.86), respectively. Conclusions eGDR, a proxy for insulin resistance, is associated with retinopathy and kidney disease in young adults with T1D. The risk of retinopathy increased with lower eGDR. The risk of kidney disease also increased with lower eGDR; however results show no association between the lowest eGDR and kidney disease. eGDR can be helpful to identify young T1D individuals at risk.
    Type of Medium: Online Resource
    ISSN: 1475-2840
    URL: Article
    DOI: 10.1186/s12933-023-01791-x
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2093769-6
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  • 5
    Online Resource
    Online Resource
    Replacing eye trackers in ongoing studies: A comparison of eye‐tracking data quality between the Tobii Pro TX300 and the Tobii Pro Spectrum
    Wiley ; 2022
    In:  Infancy Vol. 27, No. 1 ( 2022-01), p. 25-45
    Details
    In: Infancy, Wiley, Vol. 27, No. 1 ( 2022-01), p. 25-45
    Abstract: The Tobii Pro TX300 is a popular eye tracker in developmental eye‐tracking research, yet it is no longer manufactured. If a TX300 breaks down, it may have to be replaced. The data quality of the replacement eye tracker may differ from that of the TX300, which may affect the experimental outcome measures. This is problematic for longitudinal and multi‐site studies, and for researchers replacing eye trackers between studies. We, therefore, ask how the TX300 and its successor, the Tobii Pro Spectrum, compare in terms of eye‐tracking data quality. Data quality—operationalized through precision, accuracy, and data loss—was compared between eye trackers for three age groups (around 5‐months, 10‐months, and 3‐years). Precision was better for all gaze position signals obtained with the Spectrum in comparison to the TX300. Accuracy of the Spectrum was higher for the 5‐month‐old and 10‐month‐old children. For the three‐year‐old children, accuracy was similar across both eye trackers. Gaze position signals from the Spectrum exhibited lower proportions of data loss, and the duration of the data loss periods tended to be shorter. In conclusion, the Spectrum produces gaze position signals with higher data quality, especially for the younger infants. Implications for data analysis are discussed.
    Type of Medium: Online Resource
    ISSN: 1525-0008 , 1532-7078
    URL: Issue
    URL: Article
    DOI: 10.1111/infa.v27.1
    DOI: 10.1111/infa.12441
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2020049-3
    SSG: 5,2
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  • 6
    Online Resource
    Online Resource
    Early and long-term prognosis in patients with and without type 2 diabetes after carotid intervention: a Swedish nationwide propensity score matched cohort study
    Springer Science and Business Media LLC ; 2021
    In:  Cardiovascular Diabetology Vol. 20, No. 1 ( 2021-12)
    Details
    In: Cardiovascular Diabetology, Springer Science and Business Media LLC, Vol. 20, No. 1 ( 2021-12)
    Abstract: To investigate early and long-term outcomes after treatment of carotid artery stenosis in patients with type 2 diabetes (T2D) compared to patients without T2D. Design/method This observational nationwide population-based retrospective cohort study investigated all T2D patients treated for carotid stenosis registered in the National Swedish Vascular Surgery and the National Diabetes Registries. Data was collected prospectively for all patients after carotid intervention, during 2009–2015. We estimated crude early (within 30-days) hazard ratios (HRs) risk of stroke and death, and long-term HRs risk, adjusted for confounders with 95% confidence intervals (CIs), for stroke and death and major adverse cardiovascular events (MACE) by using inverse probability of treatment weighting matching. Results A total of 1341 patients with T2D and 4162 patients without T2D were included; 89% treated for symptomatic carotid stenosis, 96% with carotid endarterectomy. There was an increased early risk, HRs (95% CI), for stroke in T2D patients 1.65 (1.17–2.32), whereas risk for early death 1.00 (0.49–2.04) was similar in both groups. During a median follow-up of 4.3 (T2D) and 4.6 (without T2D), with a maximum of 8.0 years; after propensity score matching there was an increased HRs (95% CI) of stroke 1.27 (1.05–1.54) and death 1.27 (1.10–1.47) in T2D patients compared to patients without T2D. Corresponding numbers for MACE were 1.21 (1.08–1.35). Conclusions Patients with T2D run an increased risk for stroke, death, and MACE after carotid intervention. They also have an increased perioperative risk for stroke, but not for death.
    Type of Medium: Online Resource
    ISSN: 1475-2840
    URL: Article
    DOI: 10.1186/s12933-021-01282-x
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2093769-6
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  • 7
    Online Resource
    Online Resource
    Social context modulates basic properties of oculomotor control
    University of Bern ; 2016
    In:  Journal of Eye Movement Research Vol. 9, No. 2 ( 2016-02-22)
    Details
    In: Journal of Eye Movement Research, University of Bern, Vol. 9, No. 2 ( 2016-02-22)
    Abstract: Experiments performed in a lab are often considered generalizable over both people and social settings. The problems with generalizing over different groups of people are well known, but it is only recently that changes in behavior depending on the social setting have been examined. Large changes in behavior can be seen in trivial cognitive tasks, depending on whether the participant is alone or if other people are present. However, there are very few studies which have measured eye movements in social settings. In this paper, we used the antisaccade task to test whether basic parameters of oculomotor control are sensitive to the size of an experimental group. 70 participants conducted 48 antisaccade trials in groups of one to seven people in a classroom equipped with multiple eye trackers. The results show that for horizontal saccades, but not for vertical saccades, participants make significantly more antisaccade errors when the group size become larger. The group size did however not significantly predict a change in antisaccade latency. These results are in line with a number of recent studies on social attention showing that the mere presence of other people in the room can modulate several aspects of performance, and show that behavior in a lab might not be easily generalizable to everyday life or social situations. Finally, from a methodological viewpoint, the results show that the group size should be considered when testing participants in a social setting.
    Type of Medium: Online Resource
    ISSN: 1995-8692
    URL: Article
    DOI: 10.16910/jemr.9.2.5
    Language: Unknown
    Publisher: University of Bern
    Publication Date: 2016
    detail.hit.zdb_id: 2578662-3
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  • 8
    Online Resource
    Online Resource
    Dapagliflozin is associated with lower risk of cardiovascular events and all‐cause mortality in people with type 2 diabetes ( CVD‐REAL Nordic ) when compared with dipeptidyl peptidase‐4 inhibitor therapy: A multinational observational study
    Wiley ; 2018
    In:  Diabetes, Obesity and Metabolism Vol. 20, No. 2 ( 2018-02), p. 344-351
    Details
    In: Diabetes, Obesity and Metabolism, Wiley, Vol. 20, No. 2 ( 2018-02), p. 344-351
    Abstract: To compare the sodium‐glucose‐cotransporter‐2 (SGLT‐2) inhibitor dapagliflozin with dipeptidyl peptidase‐4 (DPP‐4) inhibitors with regard to risk associations with major adverse cardiovascular (CV) events (MACE; non‐fatal myocardial infarction, non‐fatal stroke or cardiovascular mortality), hospitalization for heart failure (HHF), atrial fibrillation and severe hypoglycaemia in patients with type 2 diabetes (T2D) in a real‐world setting. Methods All patients with T2D prescribed glucose‐lowering drugs (GLDs) during 2012 to 2015 were identified in nationwide registries in Denmark, Norway and Sweden. Patients were divided into two groups: new users of dapagliflozin and new users of DPP‐4 inhibitors, matched 1:3 by propensity score, calculated by patient characteristics, comorbidities and drug treatment. Cox survival models were used to estimate hazard ratio (HR) per country separately, and a weighted average was calculated. Results After matching, a total of 40 908 patients with T2D were identified as new users of dapagliflozin (n = 10 227) or a DPP‐4 inhibitor (n = 30 681). The groups were well balanced at baseline; their mean age was 61 years and 23% had CV disease. The mean follow‐up time was 0.95 years, with a total of 38 760 patient‐years. Dapagliflozin was associated with a lower risk of MACE, HHF and all‐cause mortality compared with DPP‐4 inhibitors: HRs 0.79 (95% confidence interval [CI] 0.67‐0.94), 0.62 (95% CI 0.50‐0.77), and 0.59 (95% CI 0.49‐0.72), respectively. Numerically lower, but non‐significant HRs were observed for myocardial infarction (0.91 [95% CI 0.72‐1.16] ), stroke (0.79 [95% CI 0.61‐1.03]) and CV mortality (0.76 [95% CI 0.53‐1.08] ) Neutral associations with atrial fibrillation and severe hypoglycaemia were observed. Conclusions Dapagliflozin was associated with lower risks of CV events and all‐cause mortality compared with DPP‐4 inhibitors in a real‐world clinical setting and a broad T2D population.
    Type of Medium: Online Resource
    ISSN: 1462-8902 , 1463-1326
    URL: Issue
    URL: Article
    DOI: 10.1111/dom.2018.20.issue-2
    DOI: 10.1111/dom.13077
    Language: English
    Publisher: Wiley
    Publication Date: 2018
    detail.hit.zdb_id: 2004918-3
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  • 9
    Online Resource
    Online Resource
    The majority of people with type 1 diabetes and multiple daily insulin injections benefit from using continuous glucose monitoring: An analysis based on the GOLD randomized trial ( GOLD‐5 )
    Wiley ; 2021
    In:  Diabetes, Obesity and Metabolism Vol. 23, No. 2 ( 2021-02), p. 619-630
    Details
    In: Diabetes, Obesity and Metabolism, Wiley, Vol. 23, No. 2 ( 2021-02), p. 619-630
    Abstract: To identify responders to continuous glucose monitoring (CGM) in relation to reductions in HbA1c and percentage of time spent in hypoglycaemia after initiation of CGM for individuals with type 1 diabetes treated with multiple daily insulin injections. Materials and Methods We analysed data from 142 participants in the GOLD randomized clinical trial. We evaluated how many lowered their HbA1c by more than 0.4% ( 〉 4.7 mmol/mol) or decreased the time spent in hypoglycaemia over 24 hours by more than 20 or 30 minutes, and which baseline variables were associated with those improvements. Results Lower reduction of HbA1c was associated with greater reduction of hypoglycaemia (r = −0.52; P   〈  .0001). During CGM, 47% of participants lowered their HbA1c values by more than 0.4% ( 〉 4.7 mmol/mol) than with self‐measurement of blood glucose, and 47% decreased the time spent in hypoglycaemia by more than 20 minutes over 24 hours. Overall, 78% either reduced their HbA1c by more than 0.4% ( 〉 4.7 mmol/mol) or the time spent in hypoglycaemia by more than 20 minutes over 24 hours, but only 14% improved both. Higher HbA1c, a lower percentage of time at less than 3.0 or 3.9 mmol/L, a lower coefficient of variation (CV) and a higher percentage of time above 13.9 mmol/L ( P = .016) were associated with greater HbA1c reduction during CGM. The variables associated with a greater reduction of time in hypoglycaemia were female sex, greater time with glucose levels at less than 3.0 mmol/L, higher CV, and higher hypoglycaemia confidence as evaluated by a hypoglycaemic confidence questionnaire. Conclusion The majority of people with type 1 diabetes managed by multiple daily insulin injections benefit from CGM; some experienced reduced HbA1c while others reduced the time spent in hypoglycaemia. These factors need to be considered by healthcare professionals and decision‐makers for reimbursement and diabetes guidelines.
    Type of Medium: Online Resource
    ISSN: 1462-8902 , 1463-1326
    URL: Issue
    URL: Article
    DOI: 10.1111/dom.v23.2
    DOI: 10.1111/dom.14257
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2004918-3
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  • 10
    Online Resource
    Online Resource
    Effect of compressed offline foveated video on viewing behavior and subjective quality
    Association for Computing Machinery (ACM) ; 2010
    In:  ACM Transactions on Multimedia Computing, Communications, and Applications Vol. 6, No. 1 ( 2010-02), p. 1-14
    Details
    In: ACM Transactions on Multimedia Computing, Communications, and Applications, Association for Computing Machinery (ACM), Vol. 6, No. 1 ( 2010-02), p. 1-14
    Abstract: Offline foveation is a technique to improve the compression efficiency of digitized video. The general idea behind offline foveation is to blur video regions where no or a small number of previewers look without decreasing the subjective quality for later viewers. It relies on the fact that peripheral vision is reduced compared to central vision, and the observation that during free-viewing humans' gaze positions generally coincide when watching video. In this article, we conduct two experiments to assess how offline foveation affects viewing behavior and subjective quality. In the first experiment, 15 subjects free-viewed six video clips before and after offline foveation whereas in the second experiment we had 17 subjects assessing the quality of these videos after one, two, and three consecutive viewings. Eye movements were measured during the experiments. Results showed that, although offline foveation prior to encoding with H.264 yielded data reductions up to 52% (20% average) on the tested videos, it had little or no effect on where people looked, their intersubject dispersion, fixation duration, saccade amplitude, or the experienced quality during first-time viewing. However, seeing the videos more than once increased the intersubject dispersion and decreased the subjective quality. In view of these results, we discuss the usage of offline foveated video in practical applications.
    Type of Medium: Online Resource
    ISSN: 1551-6857 , 1551-6865
    URL: Article
    DOI: 10.1145/1671954.1671958
    RVK:
    ST 325
    Language: English
    Publisher: Association for Computing Machinery (ACM)
    Publication Date: 2010
    detail.hit.zdb_id: 2182650-X
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