In:
International Psychogeriatrics, Cambridge University Press (CUP), Vol. 14, No. 3 ( 2002-09), p. 239-248
Kurzfassung:
Background: The purpose of this study was to examine if Type 2 diabetes mellitus is a risk factor for dementia in very old age, specifically for Alzheimer's disease (AD) and vascular dementia (VaD). Methods : We evaluated the risk of dementia in relation to Type 2 diabetes using a population-based sample of 702 individuals aged 80 years and older (mean age 83 years). A total of 187 persons received a dementia diagnosis. Thirty-one individuals had a diabetes diagnosis prior to onset of the dementia. Results : Cox proportional hazard analyses, adjusted for age, gender, education, smoking habits, and circulatory diseases, indicated an elevated risk to develop VaD (relative risk = 2.54, 95% confidence interval 1.35–4.78) in individuals with diabetes mellitus. No association was found between diabetes and AD. Conclusion : Type 2 diabetes is selectively related to the different subtypes of dementia. There is no increased risk of AD but more than a twofold risk of VaD in persons with diabetes.
Materialart:
Online-Ressource
ISSN:
1041-6102
,
1741-203X
DOI:
10.1017/S104161020200844X
Sprache:
Englisch
Verlag:
Cambridge University Press (CUP)
Publikationsdatum:
2002
ZDB Id:
2147136-8
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