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  • 1
    Online Resource
    Online Resource
    The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project
    Wiley ; 2017
    In:  Ecology and Evolution Vol. 7, No. 1 ( 2017-01), p. 145-188
    Details
    In: Ecology and Evolution, Wiley, Vol. 7, No. 1 ( 2017-01), p. 145-188
    Abstract: The PREDICTS project—Projecting Responses of Ecological Diversity In Changing Terrestrial Systems ( https://www.nhm.ac.uk/our-science/our-work/biodiversity/predicts.html )—has collated from published studies a large, reasonably representative database of comparable samples of biodiversity from multiple sites that differ in the nature or intensity of human impacts relating to land use. We have used this evidence base to develop global and regional statistical models of how local biodiversity responds to these measures. We describe and make freely available this 2016 release of the database, containing more than 3.2 million records sampled at over 26,000 locations and representing over 47,000 species. We outline how the database can help in answering a range of questions in ecology and conservation biology. To our knowledge, this is the largest and most geographically and taxonomically representative database of spatial comparisons of biodiversity that has been collated to date; it will be useful to researchers and international efforts wishing to model and understand the global status of biodiversity.
    Type of Medium: Online Resource
    ISSN: 2045-7758 , 2045-7758
    URL: Issue
    URL: Article
    DOI: 10.1002/ece3.2017.7.issue-1
    DOI: 10.1002/ece3.2579
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2635675-2
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  • 2
    Online Resource
    Online Resource
    Self-expanding Transcatheter vs Surgical Aortic Valve Replacement in Intermediate-Risk Patients : 5-Year Outcomes of the SURTAVI Randomized Clinical Trial
    American Medical Association (AMA) ; 2022
    In:  JAMA Cardiology Vol. 7, No. 10 ( 2022-10-01), p. 1000-
    Details
    In: JAMA Cardiology, American Medical Association (AMA), Vol. 7, No. 10 ( 2022-10-01), p. 1000-
    Abstract: In patients with severe aortic valve stenosis at intermediate surgical risk, transcatheter aortic valve replacement (TAVR) with a self-expanding supra-annular valve was noninferior to surgery for all-cause mortality or disabling stroke at 2 years. Comparisons of longer-term clinical and hemodynamic outcomes in these patients are limited. Objective To report prespecified secondary 5-year outcomes from the Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI) randomized clinical trial. Design, Setting, and Participants SURTAVI is a prospective randomized, unblinded clinical trial. Randomization was stratified by investigational site and need for revascularization determined by the local heart teams. Patients with severe aortic valve stenosis deemed to be at intermediate risk of 30-day surgical mortality were enrolled at 87 centers from June 19, 2012, to June 30, 2016, in Europe and North America. Analysis took place between August and October 2021. Intervention Patients were randomized to TAVR with a self-expanding, supra-annular transcatheter or a surgical bioprosthesis. Main Outcomes and Measures The prespecified secondary end points of death or disabling stroke and other adverse events and hemodynamic findings at 5 years. An independent clinical event committee adjudicated all serious adverse events and an independent echocardiographic core laboratory evaluated all echocardiograms at 5 years. Results A total of 1660 individuals underwent an attempted TAVR (n = 864) or surgical (n = 796) procedure. The mean (SD) age was 79.8 (6.2) years, 724 (43.6%) were female, and the mean (SD) Society of Thoracic Surgery Predicted Risk of Mortality score was 4.5% (1.6%). At 5 years, the rates of death or disabling stroke were similar (TAVR, 31.3% vs surgery, 30.8%; hazard ratio, 1.02 [95% CI, 0.85-1.22]; P  =   .85). Transprosthetic gradients remained lower (mean [SD], 8.6 [5.5] mm Hg vs 11.2 [6.0] mm Hg; P   & amp;lt; .001) and aortic valve areas were higher (mean [SD], 2.2 [0.7] cm 2 vs 1.8 [0.6] cm 2 ; P   & amp;lt; .001) with TAVR vs surgery. More patients had moderate/severe paravalvular leak with TAVR than surgery (11 [3.0%] vs 2 [0.7%] ; risk difference, 2.37% [95% CI, 0.17%- 4.85%]; P  = .05). New pacemaker implantation rates were higher for TAVR than surgery at 5 years (289 [39.1%] vs 94 [15.1%] ; hazard ratio, 3.30 [95% CI, 2.61-4.17]; log-rank P   & amp;lt; .001), as were valve reintervention rates (27 [3.5%] vs 11 [1.9%] ; hazard ratio, 2.21 [95% CI, 1.10-4.45]; log-rank P  = .02), although between 2 and 5 years only 6 patients who underwent TAVR and 7 who underwent surgery required a reintervention. Conclusions and Relevance Among intermediate-risk patients with symptomatic severe aortic stenosis, major clinical outcomes at 5 years were similar for TAVR and surgery. TAVR was associated with superior hemodynamic valve performance but also with more paravalvular leak and valve reinterventions.
    Type of Medium: Online Resource
    ISSN: 2380-6583
    URL: Article
    DOI: 10.1001/jamacardio.2022.2695
    Language: English
    Publisher: American Medical Association (AMA)
    Publication Date: 2022
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  • 3
    Online Resource
    Online Resource
    Effects of tree pollen on throughfall element fluxes in European forests
    Springer Science and Business Media LLC ; 2023
    In:  Biogeochemistry
    Details
    In: Biogeochemistry, Springer Science and Business Media LLC
    Type of Medium: Online Resource
    ISSN: 0168-2563 , 1573-515X
    URL: Article
    DOI: 10.1007/s10533-023-01082-3
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 1478541-9
    detail.hit.zdb_id: 50671-0
    SSG: 13
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  • 4
    Online Resource
    Online Resource
    CropPol : A dynamic, open and global database on crop pollination
    Wiley ; 2022
    In:  Ecology Vol. 103, No. 3 ( 2022-03)
    Details
    In: Ecology, Wiley, Vol. 103, No. 3 ( 2022-03)
    Abstract: Seventy five percent of the world's food crops benefit from insect pollination. Hence, there has been increased interest in how global change drivers impact this critical ecosystem service. Because standardized data on crop pollination are rarely available, we are limited in our capacity to understand the variation in pollination benefits to crop yield, as well as to anticipate changes in this service, develop predictions, and inform management actions. Here, we present CropPol, a dynamic, open, and global database on crop pollination. It contains measurements recorded from 202 crop studies, covering 3,394 field observations, 2,552 yield measurements (i.e., berry mass, number of fruits, and fruit density [kg/ha], among others), and 47,752 insect records from 48 commercial crops distributed around the globe. CropPol comprises 32 of the 87 leading global crops and commodities that are pollinator dependent. Malus domestica is the most represented crop (32 studies), followed by Brassica napus (22 studies), Vaccinium corymbosum (13 studies), and Citrullus lanatus (12 studies). The most abundant pollinator guilds recorded are honey bees (34.22% counts), bumblebees (19.19%), flies other than Syrphidae and Bombyliidae (13.18%), other wild bees (13.13%), beetles (10.97%), Syrphidae (4.87%), and Bombyliidae (0.05%). Locations comprise 34 countries distributed among Europe (76 studies), North America (60), Latin America and the Caribbean (29), Asia (20), Oceania (10), and Africa (7). Sampling spans three decades and is concentrated on 2001–2005 (21 studies), 2006–2010 (40), 2011–2015 (88), and 2016–2020 (50). This is the most comprehensive open global data set on measurements of crop flower visitors, crop pollinators and pollination to date, and we encourage researchers to add more datasets to this database in the future. This data set is released for non‐commercial use only. Credits should be given to this paper (i.e., proper citation), and the products generated with this database should be shared under the same license terms (CC BY‐NC‐SA).
    Type of Medium: Online Resource
    ISSN: 0012-9658 , 1939-9170
    URL: Issue
    URL: Article
    DOI: 10.1002/ecy.v103.3
    DOI: 10.1002/ecy.3614
    RVK:
    WA 15000
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 1797-8
    detail.hit.zdb_id: 2010140-5
    SSG: 12
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  • 5
    Online Resource
    Online Resource
    Incarcerated spigelian hernia mimicking diverticulitis: detection by multidetector computed tomography
    Springer Science and Business Media LLC ; 2006
    In:  International Journal of Colorectal Disease Vol. 21, No. 8 ( 2006-10-5), p. 851-853
    Details
    In: International Journal of Colorectal Disease, Springer Science and Business Media LLC, Vol. 21, No. 8 ( 2006-10-5), p. 851-853
    Type of Medium: Online Resource
    ISSN: 0179-1958 , 1432-1262
    URL: Article
    DOI: 10.1007/s00384-006-0128-3
    RVK:
    XA 50991
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2006
    detail.hit.zdb_id: 1459217-4
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  • 6
    Online Resource
    Online Resource
    Temporary Extracorporeal Membrane Oxygenation in Patients with Refractory Postoperative Cardiogenic Shock-A Single Center Experience
    Hindawi Limited ; 2003
    In:  Journal of Cardiac Surgery Vol. 18, No. 6 ( 2003-11), p. 512-518
    Details
    In: Journal of Cardiac Surgery, Hindawi Limited, Vol. 18, No. 6 ( 2003-11), p. 512-518
    Type of Medium: Online Resource
    ISSN: 0886-0440
    URL: Article
    DOI: 10.1046/j.0886-0440.2003.02061.x
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2003
    detail.hit.zdb_id: 2108425-7
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  • 7
    Online Resource
    Online Resource
    Prostaglandins Participate in the Regulation of NaCl Absorption in the Diluting Segments of the Nephron in vivo: Effects of Furosemide
    S. Karger AG ; 1982
    In:  Kidney and Blood Pressure Research Vol. 5, No. 3 ( 1982), p. 115-123
    Details
    In: Kidney and Blood Pressure Research, S. Karger AG, Vol. 5, No. 3 ( 1982), p. 115-123
    Abstract: Various studies point to a role of the renal prostaglandin (PG) system in the regulation of renal NaCl excretion. In the present experiments, distal delivery of proximal tubular fluid (DD) [(C 〈 sub 〉 H2O 〈 /sub 〉 +C 〈 sub 〉 cl 〈 /sub 〉 )/GFR×100] and distal fractional chloride absorption (DFA 〈 sub 〉 C1 〈 /sub 〉 ) [C 〈 sub 〉 H2O 〈 /sub 〉 /(C 〈 sub 〉 H2O 〈 /sub 〉 +C 〈 sub 〉 α 〈 /sub 〉 )] were studied in 6 healthy volunteers undergoing sustained water di uresis. Studies of renal function were performed during intravenous infusion of hypotonic (0.45%) saline and during additional treatment with indomethacin, furosemide and furosemide plus indomethacin. Hypotonic saline was infused at increasing rates of 0.09, 0.18, and 0.36ml min 〈 sup 〉 -1 〈 /sup 〉 kg 〈 sup 〉 -1 〈 /sup 〉 body weight each for a 45-min period. DD over all three clearance periods averaged 8.27 + 0.71 ml min 〈 sup 〉 -1 〈 /sup 〉 100 ml 〈 sup 〉 -1 〈 /sup 〉 glomerular filtration rate (GFR) during saline infusion alone and was unchanged by indomethacin (8.09 ± 0.63 ml min 〈 sup 〉 -1 〈 /sup 〉 100 ml 〈 sup 〉 -1 〈 /sup 〉 GFR).DFA 〈 sub 〉 C1 〈 /sub 〉 averaged 0.79 + 0.02 during saline and significantly increased to 0.87 + 0.01 (p 〈 0.002) during concomitant indomethacin treatment. Increased NaCl absorption in the diluting segment during indomethacin was paralleled by a decrease in urinary excretion of chloride (U 〈 sub 〉 C1 〈 /sub 〉 V) from 221 + 29 during control to 124 ± 19 µEq/min (p 〈 0.025) and in urinary excretion of PGE 〈 sub 〉 2 〈 /sub 〉 (U 〈 sub 〉 PGE2 〈 /sub 〉 V) from 1.45 + 0.12 to 0.51 + 0.09 pmol/min (p 〈 0.025). Furosemide increased U 〈 sub 〉 PGE2 〈 /sub 〉 V to 2.94 + 0.34 pmol/min (p 〈 0.05) and U 〈 sub 〉 C1 〈 /sub 〉 V to 2,590 + 128 µEq/min (p 〈 0.001). This effect was associated with an increase in DD to 26.70 + 1.33 ml min 〈 sup 〉 -1 〈 /sup 〉 100 ml” 〈 sup 〉 1 〈 /sup 〉 GFR (p 〈 0.001) and a decrease in DFA 〈 sub 〉 Cl 〈 /sub 〉 to 0.19 ± 0.02 (p 〈 0.001). Neither DD and DFA 〈 sub 〉 Cl 〈 /sub 〉 nor U 〈 sub 〉 Cl 〈 /sub 〉 V were altered during furosemide+indomethacin as compared to furosemide in spite of a marked suppression of U 〈 sub 〉 PGE2 〈 /sub 〉 V to 0.56 ± 0.13 pmol/min. Our results support the concept that renal PG participate in the regulation of NaCl absorption in the diluting segments of the nephron. Furthermore, the tubular effects of furosemide appear not to be mediated by the PG system.
    Type of Medium: Online Resource
    ISSN: 1420-4096 , 1423-0143
    URL: Article
    DOI: 10.1159/000172847
    Language: English
    Publisher: S. Karger AG
    Publication Date: 1982
    detail.hit.zdb_id: 1482922-8
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  • 8
    Online Resource
    Online Resource
    The Diagnosis of Thoracic Aortic Dissection by Noninvasive Imaging Procedures
    Massachusetts Medical Society ; 1993
    In:  New England Journal of Medicine Vol. 328, No. 1 ( 1993-01-07), p. 1-9
    Details
    In: New England Journal of Medicine, Massachusetts Medical Society, Vol. 328, No. 1 ( 1993-01-07), p. 1-9
    Type of Medium: Online Resource
    ISSN: 0028-4793 , 1533-4406
    URL: Article
    DOI: 10.1056/NEJM199301073280101
    RVK:
    XA 10000
    Language: English
    Publisher: Massachusetts Medical Society
    Publication Date: 1993
    detail.hit.zdb_id: 1468837-2
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  • 9
    Online Resource
    Online Resource
    Emergency Coronary Artery Bypass Graft Surgery for Acute Coronary Syndrome : Beating Heart Versus Conventional Cardioplegic Cardiac Arrest Strategies
    Ovid Technologies (Wolters Kluwer Health) ; 2006
    In:  Circulation Vol. 114, No. 1_supplement ( 2006-07-04)
    Details
    In: Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 114, No. 1_supplement ( 2006-07-04)
    Abstract: Background— Aim of this study was to compare the outcome of beating heart versus conventional coronary artery bypass graft (CABG) strategies in acute coronary syndromes for emergency indications. Methods and Results— 638 consecutive patients with acute coronary syndrome (ACS) receiving emergency CABG surgery via midline sternotomy from January 2000 to September 2005 were evaluated. Propensity score analysis was used to predict the probability of undergoing beating heart (BH) (n=240) versus cardioplegic cardiac arrest (CA) (n=398) strategies. Patients presented with stable hemodynamics (n=531) or in cardiogenic shock (CS) (n=107). Hospital and follow-up outcome was compared by propensity score adjusted multiregression analysis. BH included 116 on-pump and 124 off-pump (OPCAB) procedures. There was a propensity to operate CS patients on the beating heart (multivariate odds ratio [OR], 3.8; P =0.001). Under stable hemodynamics significant predictors for BH selection were logEuroSCORE 〉 20% (OR, 2.05), creatinine 〉 1.8 mg/dL (OR, 4.12), complicated percutaneous coronary intervention (OR, 1.88), ejection fraction 〈 30% (OR, 2.64), whereas left main disease (OR, 0.68), circumflex artery (OR, 0.32), and 3-vessel disease (OR, 0.67) indicated preference for cardioplegic arrest. Time from skin incision to culprit lesion revascularization was significantly reduced in BH patients. BH surgery led to a significant benefit in terms of less drainage loss, less transfusion requirement, less inotropic support, shorter ventilation time, lower stroke rate, and shorter intensive care unit stay. In CS, BH was associated with lower incidence of stroke, inotropic support, acute renal failure, new atrial fibrillation and sternal wound healing complications. In CS patients, hospital mortality rate was reduced when using beating heart strategies ( P =0.048). Overall survival, major adverse cerebral and cardiovascular event rate, and repeated revascularization was comparable during a 5-year follow-up. Conclusions— Beating heart strategies are associated with an improved hospital outcome and comparable long-term results for high-risk patients presenting acute coronary syndrome with or without CS.
    Type of Medium: Online Resource
    ISSN: 0009-7322 , 1524-4539
    URL: Article
    DOI: 10.1161/CIRCULATIONAHA.105.001545
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2006
    detail.hit.zdb_id: 1466401-X
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  • 10
    Online Resource
    Online Resource
    Configuration of Primary and Recurrent Aggressive Fibromatosis on Contrast-Enhanced MRI with an Evaluation of Potential Risk Factors for Recurrences in MRI Follow-Up
    Georg Thieme Verlag KG ; 2020
    In:  RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren Vol. 192, No. 05 ( 2020-05), p. 448-457
    Details
    In: RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, Georg Thieme Verlag KG, Vol. 192, No. 05 ( 2020-05), p. 448-457
    Abstract: Purpose To analyze the appearance of primary and recurrent aggressive fibromatosis (AF) on MRI with a focus on configuration and to determine potential risk factors for recurrences detected on MRI follow-up scans. Methods From 79 consecutive patients with histologically proven diagnosis of AF, 39 patients underwent a minimum of four 1.5 T MRI follow-up scans after resection of primary AF between 2008 and 2018. The primary and recurrent tumors were radiographically examined for configuration, limitation and extent on MRI. Epidemiological data and loco-regional subcutaneous edema, muscle edema and post-operative seroma were included. Results The mean age of the patients was 39 ± 2.6 years. Primary and recurrent AF most often occurred in the thigh. The main appearance of primary AF was significantly most often fascicular (p = 0.001–0.01) with heterogeneous and marked contrast enhancement. 21 % (n = 8) of the patients developed recurrences of AF. A fascicular configuration with homogeneous/heterogeneous contrast enhancement was the main appearance of recurrent AF, but recurrent AF appeared nodular, polycyclic, ovoid or streaky/flat as well. Recurrent AF significantly most often occurred within the first 9 months after primary tumor resection (p = 0.009), especially in patients up to 25 years of age (RR = 6.1; 95 % CI: 1.8–20.9; p = 0.004). The cases of recurrent AF were altogether significantly smaller than the primary tumors (p = 0.001). Post-treatment subcutaneous and muscle edema were present in 77 % and 56 %, respectively. Patients with muscle edema after primary tumor resection had a significantly higher risk for AF recurrences (relative risk ratio (RR) = 1.8; 95 % CI: 1.16–2.8; p = 0.0096). There was no significant difference detected in patients with complete or incomplete resection of the primary tumor. Conclusion Primary and recurrent aggressive fibromatosis has a mostly fascicular configuration, but may appear ovoid, nodular, streaky/flat or polycyclic as well. High risks for tumor recurrences are detected for patients up to 25 years of age, patients within the first 9 post-operative months and patients with muscle edema after primary tumor resection. Key points:  Citation Format
    Type of Medium: Online Resource
    ISSN: 1438-9029 , 1438-9010
    URL: Article
    DOI: 10.1055/a-1022-4546
    RVK:
    XA 10000
    Language: English
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2020
    detail.hit.zdb_id: 2031079-1
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