In:
Journal of Contemporary Medical Sciences, Naba'a Al-Hayat Foundation for Medical Sciences and Health Care, Vol. 10, No. 2 ( 2024-04-30)
Abstract:
The association between the Prothrombin G20210A mutation and recurrent pregnancy loss is well documented in the literature among different populations. A descriptive study was conducted in Omdurman Maternity Hospital, Sudan, to find the prevalence of the Prothrombin G20210A mutation among Sudanese women with recurrent pregnancy loss. Analysis of the Prothrombin G20210A mutation was performed using PCR-RFLP for 67 enrolled women with recurrent pregnancy loss of two times or more. Data analysis was performed using SPSS. The prothrombin G20210A mutation was present in 4 (6%) out of the total 67 enrolled cases; 3 (4.5%) had the GA genotype (hetrozygous), while one had the (1.5%) AA genotype. The study revealed that the Prothrombin G20210A mutation is less prevalent among Sudanese women with recurrent pregnancy loss compared to other Arab nations. A large case-control study is needed.
Type of Medium:
Online Resource
ISSN:
2413-0516
,
2415-1629
DOI:
10.22317/jcms.v10i2.1529
Language:
Unknown
Publisher:
Naba'a Al-Hayat Foundation for Medical Sciences and Health Care
Publication Date:
2024
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