In:
International Journal of Dermatology, Wiley, Vol. 44, No. 12 ( 2005-12), p. 1016-1021
Abstract:
Background Research demonstrating an increased incidence of skin cancer with psoralen plus ultraviolet A (PUVA) therapy has reflected the Caucasian experience. Our objective was to review the literature on skin cancer risk associated with long‐term PUVA therapy in non‐Caucasians. Methods Our analysis included 4294 long‐term PUVA patients in Japan, Korea, Thailand, Egypt, and Tunisia with a follow‐up period of at least 5 years. Results The relative risk of PUVA patients developing nonmelanoma skin cancer relative to general dermatology outpatients was 0.86 [CI 0.36–1.35]. Conclusions There does not appear to be an increased risk of nonmelanoma skin cancer with long‐term PUVA therapy in Asian and Arabian‐African populations. Therefore, in phototherapy risk assessment, it is important to consider the patient's skin phototype and the potential protection that more pigmented skin may confer.
Type of Medium:
Online Resource
ISSN:
0011-9059
,
1365-4632
DOI:
10.1111/ijd.2005.44.issue-12
DOI:
10.1111/j.1365-4632.2004.02322.x
Language:
English
Publisher:
Wiley
Publication Date:
2005
detail.hit.zdb_id:
2020365-2
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