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  • 1
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    Online Resource
    IN-HOSPITAL OUTCOMES OF PERCUTANEOUS TRICUSPID VALVE REPAIR AND REPLACEMENT
    Elsevier BV ; 2022
    In:  Journal of the American College of Cardiology Vol. 79, No. 9 ( 2022-03), p. 875-
    Details
    In: Journal of the American College of Cardiology, Elsevier BV, Vol. 79, No. 9 ( 2022-03), p. 875-
    Type of Medium: Online Resource
    ISSN: 0735-1097
    URL: Article
    DOI: 10.1016/S0735-1097(22)01866-6
    RVK:
    XA 17760
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2022
    detail.hit.zdb_id: 1468327-1
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  • 2
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    Online Resource
    Anomalous Origin of Right Coronary Artery Originating from the Pulmonary Trunk (ARCAPA): an Incidental Finding in a Patient Presenting with Chest Pain
    Springer Science and Business Media LLC ; 2017
    In:  Cureus
    Details
    In: Cureus, Springer Science and Business Media LLC
    Type of Medium: Online Resource
    ISSN: 2168-8184
    URL: Article
    DOI: 10.7759/cureus.1172
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2017
    detail.hit.zdb_id: 2747273-5
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  • 3
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    Abstract 10617: Non-Alcoholic Fatty Liver Disease, Heart Failure, and Long-Term Mortality: Insights From the National Health and Nutrition Examination Survey
    Ovid Technologies (Wolters Kluwer Health) ; 2022
    In:  Circulation Vol. 146, No. Suppl_1 ( 2022-11-08)
    Details
    In: Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 146, No. Suppl_1 ( 2022-11-08)
    Abstract: Objective: To evaluate the association between non-alcoholic fatty liver disease (NAFLD), heart failure (HF), and all-cause mortality. Background: Both NAFLD and HF are increasing in prevalence due to shared risk factors. Methods: We used data from the National Health and Nutrition Examination Survey (NHANES) 2005-2018 to identify non-pregnant individuals aged ≥20 years with HF and NAFLD and linked with the cause of death data from the National Center for Health Statistics. The associations between NAFLD, HF, and all-cause mortality were assessed using logistic regression and Cox proportional hazard modeling as appropriate. Results: There were 82,358,893 weighted eligible participants of whom 3,833,667 (4.7%) had NAFLD. The mean (SE) age was 51.5 (0.35) years, 45.1% women, 63.0% Non-Hispanic White and 11.8% Non-Hispanic Black. Cardiovascular comorbidities were more common in participants with NAFLD; they were more likely to have hypertension (81.7% vs 53.5%), diabetes (65.1% vs 17.1%), stroke (7.3% vs 4.1%), coronary artery disease (14.9% vs 8.4%), or HF (10.5% v s 3.5%) compared with participants without NAFLD. In multivariate logistic regression models adjusting for age, race/ethnicity and sex, participants with NAFLD were 3.5 times more likely to have HF [aOR, 95% CI: 3.47 (1.98-6.06)]. Older age, male sex, presence of diabetes and coronary artery disease were associated with higher odds of HF in participants with established NAFLD. At the end of the follow-up period, participants with NAFLD had higher all-cause mortality compared with participants without NAFLD [HR(95% CI): 1.93 (1.24-2.99), p 〈 0.001]. Conclusion: In this analysis of US adults, ambulatory participants with NAFLD were ~3.5 times more likely to have HF, and twice as likely to experience mortality compared with participants without NAFLD. Further studies are needed to identify the possible linkage between NAFLD and HF beyond the shared risk factor pathogenesis.
    Type of Medium: Online Resource
    ISSN: 0009-7322 , 1524-4539
    URL: Article
    DOI: 10.1161/circ.146.suppl_1.10617
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2022
    detail.hit.zdb_id: 1466401-X
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  • 4
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    Online Resource
    Abstract 12098: Contemporary Trends in Utilization and Outcomes of Percutaneous Left Atrial Appendage Occlusion in the United States
    Ovid Technologies (Wolters Kluwer Health) ; 2022
    In:  Circulation Vol. 146, No. Suppl_1 ( 2022-11-08)
    Details
    In: Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 146, No. Suppl_1 ( 2022-11-08)
    Abstract: Background: Percutaneous left atrial appendage occlusion (pLAAO) is an alternative stroke prevention strategy in patients with atrial fibrillation who are poor candidates for long-term anticoagulation. Methods: We used the National Inpatient Sample to identify adult hospitalizations of patients who underwent pLAAO from 2016 to 2019. Outcomes of interest included peri-procedural complications, in-hospital death, and length of stay (LOS). Major adverse events were defined as a composite of in-hospital mortality, cardiac arrest, new pacemaker implantation, cardiac tamponade, bleeding requiring transfusion, stroke/TIA, AKI requiring dialysis, and systemic embolization. Trends in outcomes were examined using linear regression for continuous variables and binary logistic regression for categorical variables. Results: We found a total of 61090 pLAAO procedures (mean age 76.1 years, 41.7% female, 88.3% at urban teaching hospitals)— 5305 procedures in 2016, 11125 in 2017, 17885 in 2018, and 26775 in 2019. As compared to 2016-2017, patients in 2018-2019 were older (75.7 vs 76.3 years; p 〈 0.01) and more comorbid (Elixhauser comorbidity index of ≥5 in 38.4% vs 41.4%; p=0.01). Major adverse events occurred in 2.4%, and decreased from 2.8% in 2016 to 2.1% in 2019 (p=0.04); primarily driven by a decrease in systemic embolization and stroke/TIA. Overall in-hospital mortality was 0.15%, and decreased from 0.28% in 2016 to 0.15% in 2019 but statistical significance was not achieved (p=0.15). Mean LOS decreased from 1.5 days in 2016 to 1.3 days in 2019 (p 〈 0.01) suggesting that more single-day admissions occurred. Conclusion: There was a 400% increase in the annual volume of pLAAO from 2016 to 2019 signifying a large eligible patient population and increasing assimilation of pLAAO into clinical practice. Most complications decreased despite an older and more comorbid patient population which might be explained by improving operator technique and procedural protocols.
    Type of Medium: Online Resource
    ISSN: 0009-7322 , 1524-4539
    URL: Article
    DOI: 10.1161/circ.146.suppl_1.12098
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2022
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  • 5
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    Online Resource
    Abstract 15083: Chronicity of Heart Failure, In-Hospital Clinical Trajectory, and Post-Discharge Outcomes Among Patients Hospitalized for Heart Failure
    Ovid Technologies (Wolters Kluwer Health) ; 2022
    In:  Circulation Vol. 146, No. Suppl_1 ( 2022-11-08)
    Details
    In: Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 146, No. Suppl_1 ( 2022-11-08)
    Abstract: Introduction: Among patients hospitalized for HF, patients hospitalized with worsening chronic heart failure (WCHF) are at increased risk for morbidity and mortality compared with those who are recently diagnosed with HF. Whether there are differences in clinical course during hospitalization for HF is unclear. Methods: We pooled 735 participants hospitalized for HF in the DOSE, CARRESS, and ROSE trials. We grouped participants by whether HF was recently diagnosed (≤12 months) or WHCF ( 〉 12 months). We compared changes in congestion, kidney function, and symptoms during hospitalization, as well as early post-discharge kidney and mortality outcomes. Results: Overall, 132 (18%) had recently diagnosed HF and 603 (82%) had WCHF. Compared with WCHF, patients with recently diagnosed HF tended to have lower serum creatinine and higher systolic blood pressure, ejection fraction, and serum NT-proBNP (all p 〈 0.05). In the first 72 hours, changes in body weight, global well-being visual analog scale, serum creatinine, and serum NT-proBNP, as well as net fluid loss were similar between patients with recently diagnosed versus WCHF (all p 〉 0.15) ( Figure ). Recently diagnosed HF showed improved dyspnea at 72 hours (p=0.03). There was no difference in change in serum creatinine from baseline to 60 days (p=0.75). There was a trend toward significantly increased odds of mortality during study follow-up (adjusted odds ratio 1.96 [95% confidence interval 0.97-3.94] , p=0.06). Conclusion: Patients hospitalized for recently diagnosed and WCHF have generally similar in-hospital clinical trajectories, and similar changes in kidney function early post-discharge. Despite these similarities and adjustment for other clinical factors, patients with WCHF remain at increased risk for post-discharge mortality as compared with patients who are more recently diagnosed.
    Type of Medium: Online Resource
    ISSN: 0009-7322 , 1524-4539
    URL: Article
    DOI: 10.1161/circ.146.suppl_1.15083
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2022
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  • 6
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    Abstract 542: Race, Sex, And Age Differences In Peripheral Arterial Disease-related Mortality In The United States, 2000 To 2019
    Ovid Technologies (Wolters Kluwer Health) ; 2022
    In:  Arteriosclerosis, Thrombosis, and Vascular Biology Vol. 42, No. Suppl_1 ( 2022-05)
    Details
    In: Arteriosclerosis, Thrombosis, and Vascular Biology, Ovid Technologies (Wolters Kluwer Health), Vol. 42, No. Suppl_1 ( 2022-05)
    Abstract: Introduction: Peripheral arterial disease (PAD) is a progressive atherosclerotic disease associated with significant morbidity and mortality in the US, however, data regarding mortality trends is limited. This study uses national death certificate data to characterize contemporary trends in PAD-related mortality in the US. Methods: The Centers for Disease Control and Prevention Wide-Ranging OnLine Data for Epidemiologic Research (CDC WONDER) was queried for data regarding PAD-related deaths from 2000 to 2019 in the overall sample and from different demographics (age, sex, race). Crude and age-adjusted mortality rates (AAMR) per 100,000 people were calculated. Associated average percentage changes (APC) were computed using Joinpoint trend analysis software. Results: Between 2000 and 2019, a total of 1,959,050 PAD-related deaths occurred in the study population. Overall, AAMR decreased from 2000 to 2016, but remained relatively the same between 2016 to 2019. Men, Non-Hispanic (NH) Black or African American, NH American Indian or Alaska Native, and NH Asian or Pacific Islander showed a decline in AAMR. Women, NH White, Hispanic or Latino, ages 55 to 69 years, and 70 to 84 years showed initial declines, with no change in recent years. Ages 40 to 54 only had a change in crude mortality between 2002 and 2010. Overall, men, NH Black or African American individuals, and people aged 85+ were associated with the highest AAMRs of their respective subgroups throughout the study period. Notably, there was an increase in crude mortality rate amongst individuals 25-39 years of age from 2009 to 2019. Conclusion: PAD-related mortality in the US decreased from 2000 to 2016 but has stabilized in recent years. Despite improvement, disparities amongst sex, race, and age remain. Figure 1. PAD-related mortality rates by 1.A. sex 1.B. race 1.C. ages 25-54 and 1.D. ages 55-85+ in the United States, 2000 to 2019. *Indicates that APC is significantly different from zero at α=0.05.
    Type of Medium: Online Resource
    ISSN: 1079-5642 , 1524-4636
    URL: Article
    DOI: 10.1161/atvb.42.suppl_1.542
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2022
    detail.hit.zdb_id: 1494427-3
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  • 7
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    Association of Zika Virus with Myocarditis, Heart Failure, and Arrhythmias: A Literature Review
    Springer Science and Business Media LLC ; 2017
    In:  Cureus
    Details
    In: Cureus, Springer Science and Business Media LLC
    Type of Medium: Online Resource
    ISSN: 2168-8184
    URL: Article
    DOI: 10.7759/cureus.1399
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2017
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  • 8
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    Abstract 11624: Family Income and Cardiovascular Disease Risk in American Adults
    Ovid Technologies (Wolters Kluwer Health) ; 2022
    In:  Circulation Vol. 146, No. Suppl_1 ( 2022-11-08)
    Details
    In: Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 146, No. Suppl_1 ( 2022-11-08)
    Abstract: Background: Socioeconomic status is an often-overlooked risk factor for cardiovascular disease (CVD). Low family income is a measure of socioeconomic status and may portend worse CVD burden. Therefore, we assessed the association of family income with cardiovascular risk factor and disease burden in American adults. Methods: This retrospective analysis included data from participants aged ≥20 years from the National Health and Nutrition Examination Survey (NHANES) cycles between 2005 and 2018. Family income to poverty ratio (PIR) was calculated by dividing family (or individual) income by the poverty guidelines specific to the survey year and used as a measure of socioeconomic status. The association of PIR with the presence of cardiovascular risk factors and CVD as well as cardiac mortality and all-cause mortality was examined. Results: We included 35,932 unweighted participants corresponding to 207,073,472 weighted, nationally representative participants. Participants with lower PIR were often female and more likely to belong to race/ethnic minorities (non-Hispanic Black, Mexican American, other Hispanic). In addition, they were less likely to be married/living with a partner, to attain college graduation or higher, or to have health insurance. In the adjusted analysis, the prevalence odds of diabetes mellitus, hypertension, coronary artery disease (CAD), congestive heart failure (CHF), and stroke largely decreased in a step-wise manner from highest (≥5) to lowest PIR ( 〈 1) (Table 1). In the adjusted analysis, we also noted a mostly dose-dependent association of PIR with the risk of all-cause and cardiac mortality during a mean 5.7 and 5.8 years of follow up, respectively. Conclusions: Public policy efforts should be directed to alleviate these disparities to help improve cardiovascular outcomes in this vulnerable subgroup.
    Type of Medium: Online Resource
    ISSN: 0009-7322 , 1524-4539
    URL: Article
    DOI: 10.1161/circ.146.suppl_1.11624
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2022
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  • 9
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    Does Hemodynamic-Guided Heart Failure Management Reduce Hospitalization? A Systematic Review
    Springer Science and Business Media LLC ; 2017
    In:  Cureus
    Details
    In: Cureus, Springer Science and Business Media LLC
    Type of Medium: Online Resource
    ISSN: 2168-8184
    URL: Article
    DOI: 10.7759/cureus.1161
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2017
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  • 10
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    Association of Non-alcoholic Fatty Liver Disease with Conduction Defects on Electrocardiogram
    Springer Science and Business Media LLC ; 2017
    In:  Cureus
    Details
    In: Cureus, Springer Science and Business Media LLC
    Type of Medium: Online Resource
    ISSN: 2168-8184
    URL: Article
    DOI: 10.7759/cureus.1107
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2017
    detail.hit.zdb_id: 2747273-5
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