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  • 1
    Online Resource
    Online Resource
    Elsevier BV ; 2019
    In:  Topics in Companion Animal Medicine Vol. 36 ( 2019-09), p. 9-11
    In: Topics in Companion Animal Medicine, Elsevier BV, Vol. 36 ( 2019-09), p. 9-11
    Type of Medium: Online Resource
    ISSN: 1938-9736
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2019
    detail.hit.zdb_id: 2428103-7
    SSG: 22
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  • 2
    In: Veterinary Surgery, Wiley, Vol. 50, No. S1 ( 2021-07)
    Abstract: To determine the feasibility of laparoscopic liver lobectomy (LLL) in dogs by using canine cadavers and to describe the clinical application in dogs with liver disease. Study design Ex vivo experiment and descriptive case series. Sample population Twelve canine cadavers and six client‐owned dogs. Methods Cadavers underwent LLL with an endoscopic stapler. The percentage of liver lobe resected was determined by volume. The distance from the staple line to hilus was measured. Medical records of dogs undergoing LLL were reviewed. Results In cadavers ≤15 kg, left lateral lobectomy completeness was 87.3% (84.6%–96.6%), and remaining median (interquartile range) hilar length was 1 cm (0.25‐1.75). Left medial lobectomy completeness was 72.5% (66.7%–80%), and remaining hilar length was 1.6 cm (0.47‐1.75). Central division resection completeness was 68.3% (60%–92.9%), and remaining hilar length was 2.7 cm (0.8‐5). Laparoscopic liver lobectomy was not feasible for right division lobes and in cadavers 〉 15 kg. Five dogs with peripheral quadrate or left lateral lobe masses underwent stapled, partial laparoscopic lobectomy (30%–90%). One dog underwent stapled, left lateral lobectomy (90%) after open procedure conversion. Histopathological diagnoses included hepatocellular carcinoma (3), nodular hyperplasia (1), biliary cyst adenoma (1), and fibrosis (1). Conclusion Laparoscopic liver lobectomy of the left and central divisions is feasible in cadavers ≤15 kg with an endoscopic stapler. Partial LLL of the left and central divisions is feasible in select dogs with liver disease. Clinical significance Laparoscopic liver lobectomy may be a viable alternative to laparotomy in small‐to‐medium size dogs with peripheral liver masses of the left and central divisions.
    Type of Medium: Online Resource
    ISSN: 0161-3499 , 1532-950X
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 1491071-8
    SSG: 22
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  • 3
    In: Veterinary Surgery, Wiley, Vol. 53, No. 5 ( 2024-07), p. 800-807
    Abstract: To identify small animal surgery (SAS) residency program factors associated with board examination pass rates for the American College of Veterinary Surgeons (ACVS) board certification examinations. Study design Online survey. Sample population Program directors of ACVS‐registered SAS residency programs. Methods An online survey was distributed to eligible 2021 ACVS SAS residency program directors. Respondents provided program information and Phase I and Phase II board examination pass rate data from 2017 to 2021. Programs were grouped based on overall combined board examination pass rates as “excellent” (≥90%) versus “adequate” ( 〈 90%). Data were analyzed using recursive partitioning. Results Responses from 36 ACVS SAS residency programs (18 private practice [PP], 18 academic programs [AP] ) were included. Pass rates were considered “excellent” for 17/36 programs (11/17 AP, 6/17 PP). The strongest indicator of “excellent” programs was most mentors participating in rounds 〉 75% of the time. Of those, the second indicator of “excellent” programs was a soft tissue caseload of 〈 7 surgeries/resident/week. If the soft tissue caseload was 〉 7 surgeries/resident/week, a high orthopedic caseload ( 〉 9 surgeries/resident/week) was indicative of “excellent” programs. If most mentors were not participating in rounds 〉 75% of the time, APs were more likely to be “excellent.” Conclusion SAS APs may have higher ACVS board examination pass rates. Mentor involvement, caseload, and residency practice type may influence board examination pass rates. Clinical impact ACVS SAS residency programs' board examination pass rates may improve by optimizing mentor involvement and caseload regardless of practice type.
    Type of Medium: Online Resource
    ISSN: 0161-3499 , 1532-950X
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2024
    detail.hit.zdb_id: 1491071-8
    SSG: 22
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  • 4
    Online Resource
    Online Resource
    American Veterinary Medical Association (AVMA) ; 2021
    In:  Journal of the American Veterinary Medical Association Vol. 258, No. 11 ( 2021-06-01), p. 1229-1235
    In: Journal of the American Veterinary Medical Association, American Veterinary Medical Association (AVMA), Vol. 258, No. 11 ( 2021-06-01), p. 1229-1235
    Abstract: To describe surgical management and associated outcomes for dogs with primary spontaneous pneumothorax. ANIMALS 110 client-owned dogs with primary spontaneous pneumothorax that underwent surgical management. PROCEDURES Medical records at 7 veterinary teaching hospitals were reviewed. Data collected included signalment, history, clinical signs, radiographic and CT findings, surgical methods, intraoperative and postoperative complications, outcomes, and histopathologic findings. Follow-up information was obtained by contacting the referring veterinarian or owner. RESULTS 110 dogs were included, with a median follow-up time of 508 days (range, 3 to 2,377 days). Ninety-nine (90%) dogs underwent median sternotomy, 9 (8%) underwent intercostal thoracotomy, and 2 (2%) underwent thoracoscopy as the sole intervention. Bullous lesions were most commonly found in the left cranial lung lobe (51/156 [33%] lesions) and right cranial lung lobe (37/156 [24%] lesions). Of the 100 dogs followed up for 〉 30 days, 13 (13%) had a recurrence of pneumothorax, with median time between surgery and recurrence of 9 days. Recurrence was significantly more likely to occur ≤ 30 days after surgery, compared with 〉 30 days after surgery. Recurrence 〉 30 days after surgery was rare (3 [3%]). No risk factors for recurrence were identified. CONCLUSIONS AND CLINICAL RELEVANCE Lung lobectomy via median sternotomy resulted in resolution of pneumothorax in most dogs with primary spontaneous pneumothorax. Recurrence of pneumothorax was most common in the immediate postoperative period, which may have reflected failure to identify lesions during the initial thoracic exploration, rather than development of additional bullae.
    Type of Medium: Online Resource
    ISSN: 0003-1488
    Language: Unknown
    Publisher: American Veterinary Medical Association (AVMA)
    Publication Date: 2021
    detail.hit.zdb_id: 2904887-4
    SSG: 22
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  • 5
    Online Resource
    Online Resource
    American Veterinary Medical Association (AVMA) ; 2023
    In:  Journal of the American Veterinary Medical Association ( 2023-08-29), p. 1-6
    In: Journal of the American Veterinary Medical Association, American Veterinary Medical Association (AVMA), ( 2023-08-29), p. 1-6
    Abstract: To identify risk factors for intra- and postoperative ventricular arrhythmias (VAs) and in-hospital mortality in dogs undergoing splenectomy for splenic masses. ANIMALS 308 dogs. METHODS Records from 2010 through 2018 were reviewed for dogs undergoing splenectomy for a splenic mass. Clinical and laboratory findings on admission, diagnostic imaging, anesthesia, surgery and pathology reports, treatment records, and in-hospital mortality were evaluated with logistic regression. RESULTS VAs occurred in 138 (44.8%) dogs (126/308 [40.9%] postoperative, 51/308 [16.6%] intraoperative, 26/308 [8.4%] preoperative), with 50/308 (16.2%) dogs having more than one type of VA. Increasing heart rate and body weight, decreasing PCV and platelet count, hemoperitoneum, receipt of a transfusion, and diagnosis of hemangiosarcoma were associated with the presence of intra- and postoperative VAs on univariable analysis (all P 〈 .001). On multivariable analysis, hemoperitoneum ( P 〈 .001 , 〈 .001), increasing body weight ( P = .026, 〈 .001), and increasing heart rate ( P = .028, 〈 .001) were significant for intra- and postoperative VAs, respectively. Twenty dogs died (20/308 [6.5%]; 14/138 [10.1%] with VAs, 6/170 [3.5%] without VAs). Intra- and postoperative VAs were associated with in-hospital mortality ( P = .009, .025, respectively). CLINICAL RELEVANCE Perioperative VAs were common and odds of VAs were increased with hemoperitoneum, increasing heart rate, and increasing body weight. Presence of VAs increased the odds of in-hospital mortality. Despite this, the overall in-hospital mortality rate was low (6.5%), indicating a good prognosis for survival of surgery in dogs with splenic masses, regardless of the presence of VAs or hemoperitoneum.
    Type of Medium: Online Resource
    ISSN: 0003-1488
    Language: Unknown
    Publisher: American Veterinary Medical Association (AVMA)
    Publication Date: 2023
    detail.hit.zdb_id: 2904887-4
    SSG: 22
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  • 6
    In: Monthly Notices of the Royal Astronomical Society, Oxford University Press (OUP), Vol. 507, No. 2 ( 2021-09-02), p. 2782-2803
    Abstract: We present the bright (Vmag = 9.12), multiplanet system TOI-431, characterized with photometry and radial velocities (RVs). We estimate the stellar rotation period to be 30.5 ± 0.7 d using archival photometry and RVs. Transiting Exoplanet Survey Satellite (TESS) objects of Interest (TOI)-431 b is a super-Earth with a period of 0.49 d, a radius of 1.28 ± 0.04 R⊕, a mass of 3.07 ± 0.35 M⊕, and a density of 8.0 ± 1.0 g cm−3; TOI-431 d is a sub-Neptune with a period of 12.46 d, a radius of 3.29 ± 0.09 R⊕, a mass of $9.90^{+1.53}_{-1.49}$ M⊕, and a density of 1.36 ± 0.25 g cm−3. We find a third planet, TOI-431 c, in the High Accuracy Radial velocity Planet Searcher RV data, but it is not seen to transit in the TESS light curves. It has an Msin i of $2.83^{+0.41}_{-0.34}$ M⊕, and a period of 4.85 d. TOI-431 d likely has an extended atmosphere and is one of the most well-suited TESS discoveries for atmospheric characterization, while the super-Earth TOI-431 b may be a stripped core. These planets straddle the radius gap, presenting an interesting case-study for atmospheric evolution, and TOI-431 b is a prime TESS discovery for the study of rocky planet phase curves.
    Type of Medium: Online Resource
    ISSN: 0035-8711 , 1365-2966
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2021
    detail.hit.zdb_id: 2016084-7
    SSG: 16,12
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  • 7
    In: The Astronomical Journal, American Astronomical Society, Vol. 160, No. 5 ( 2020-11-01), p. 235-
    Abstract: We present the discovery of two new 10 day period giant planets from the Transiting Exoplanet Survey Satellite mission, whose masses were precisely determined using a wide diversity of ground-based facilities. TOI-481 b and TOI-892 b have similar radii (0.99 ± 0.01 R J and 1.07 ± 0.02 R J , respectively), and orbital periods (10.3311 days and 10.6266 days, respectively), but significantly different masses (1.53 ± 0.03 M J versus 0.95 ± 0.07 M J , respectively). Both planets orbit metal-rich stars ( [ Fe / H ] = + 0.26 ± 0.05 dex and [ Fe / H ] = + 0.24 ± 0.05 for TOI-481 and TOI-892, respectively) but at different evolutionary stages. TOI-481 is a M ⋆  = 1.14 ± 0.02 M ⊙ , R ⋆  = 1.66 ± 0.02 R ⊙ G-type star ( T eff = 5735 ± 72 K), that with an age of 6.7 Gyr, is in the turn-off point of the main sequence. TOI-892 on the other hand, is a F-type dwarf star ( T eff = 6261 ± 80 K), which has a mass of M ⋆  = 1.28 ± 0.03 M ⊙ and a radius of R ⋆  = 1.39 ± 0.02 R ⊙ . TOI-481 b and TOI-892 b join the scarcely populated region of transiting gas giants with orbital periods longer than 10 days, which is important to constrain theories of the formation and structure of hot Jupiters.
    Type of Medium: Online Resource
    ISSN: 0004-6256 , 1538-3881
    RVK:
    Language: Unknown
    Publisher: American Astronomical Society
    Publication Date: 2020
    detail.hit.zdb_id: 2207625-6
    detail.hit.zdb_id: 2003104-X
    SSG: 16,12
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  • 8
    In: Appetite, Elsevier BV, Vol. 58, No. 2 ( 2012-4), p. 754-757
    Type of Medium: Online Resource
    ISSN: 0195-6663
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2012
    detail.hit.zdb_id: 1461347-5
    SSG: 12
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  • 9
    In: Frontiers in Endocrinology, Frontiers Media SA, Vol. 13 ( 2022-8-5)
    Abstract: Polycystic ovary syndrome (PCOS) is associated with elevated androgen and luteinizing hormone (LH) secretion and with oligo/anovulation. Evidence indicates that elevated androgens impair sex steroid hormone feedback regulation of pulsatile LH secretion. Hyperandrogenemia in PCOS may also disrupt the preovulatory LH surge. The mechanisms through which this might occur, however, are not fully understood. Kisspeptin (KISS1) neurons of the rostral periventricular area of the third ventricle (RP3V) convey hormonal cues to gonadotropin-releasing hormone (GnRH) neurons. In rodents, the preovulatory surge is triggered by these hormonal cues and coincident timing signals from the central circadian clock in the suprachiasmatic nucleus (SCN). Timing signals are relayed to GnRH neurons, in part, via projections from SCN arginine-vasopressin (AVP) neurons to RP3V KISS1 neurons. Because rodent SCN cells express androgen receptors (AR), we hypothesized that these circuits are impaired by elevated androgens in a mouse model of PCOS. In prenatally androgen-treated (PNA) female mice, SCN Ar expression was significantly increased compared to that found in prenatally vehicle-treated mice. A similar trend was seen in the number of Avp -positive SCN cells expressing Ar . In the RP3V, the number of kisspeptin neurons was preserved. Anterograde tract-tracing, however, revealed reduced SCN AVP neuron projections to the RP3V and a significantly lower proportion of RP3V KISS1 neurons with close appositions from SCN AVP fibers. Functional assessments showed, on the other hand, that RP3V KISS1 neuron responses to AVP were maintained in PNA mice. These findings indicate that PNA changes some of the neural circuits that regulate the preovulatory surge. These impairments might contribute to ovulatory dysfunction in PNA mice modeling PCOS.
    Type of Medium: Online Resource
    ISSN: 1664-2392
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2592084-4
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  • 10
    In: Journal of Bacteriology, American Society for Microbiology, Vol. 186, No. 7 ( 2004-04), p. 1933-1944
    Abstract: We report the complete genome sequence of enterobacteriophage SP6, which infects Salmonella enterica serovar Typhimurium. The genome contains 43,769 bp, including a 174-bp direct terminal repeat. The gene content and organization clearly place SP6 in the coliphage T7 group of phages, but there is ∼5 kb at the right end of the genome that is not present in other members of the group, and the homologues of T7 genes 1.3 through 3 appear to have undergone an unusual reorganization. Sequence analysis identified 10 putative promoters for the SP6-encoded RNA polymerase and seven putative rho-independent terminators. The terminator following the gene encoding the major capsid subunit has a termination efficiency of about 50% with the SP6-encoded RNA polymerase. Phylogenetic analysis of phages related to SP6 provided clear evidence for horizontal exchange of sequences in the ancestry of these phages and clearly demarcated exchange boundaries; one of the recombination joints lies within the coding region for a phage exonuclease. Bioinformatic analysis of the SP6 sequence strongly suggested that DNA replication occurs in large part through a bidirectional mechanism, possibly with circular intermediates.
    Type of Medium: Online Resource
    ISSN: 0021-9193 , 1098-5530
    Language: English
    Publisher: American Society for Microbiology
    Publication Date: 2004
    detail.hit.zdb_id: 1481988-0
    SSG: 12
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