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  • 1
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 1950
    In:  Journal of the Marine Biological Association of the United Kingdom Vol. 29, No. 1 ( 1950-04), p. 185-239
    In: Journal of the Marine Biological Association of the United Kingdom, Cambridge University Press (CUP), Vol. 29, No. 1 ( 1950-04), p. 185-239
    Abstract: The volumetric and qualitative analysis of the food of Gadus minutus has been discussed. The post-larvae feed entirely on copepods, mostly Pseudocalanus elongatus . The O-group feeds on copepods, small decapods, amphipods, polychaetes and isopods. The adolescent and adult groups feed on larger decapods like Processa canaliculata, Galathea spp. and Portunus spp., fish, polychaetes and amphipods. The age and rate of growth of G. minutus have been computed from a study of the supra-occipital crest. These age determinations have been correlated with the age determined by scales, otoliths and size-analysis. Back-calculations have been made by graphical method and by using the Lea-Dahl formula. The differences between the back-calculated lengths and actual observed lengths are negligible.
    Type of Medium: Online Resource
    ISSN: 0025-3154 , 1469-7769
    RVK:
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 1950
    detail.hit.zdb_id: 1491269-7
    detail.hit.zdb_id: 281325-7
    SSG: 12
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  • 2
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 1996
    In:  International Journal of Technology Assessment in Health Care Vol. 12, No. 2 ( 1996), p. 299-324
    In: International Journal of Technology Assessment in Health Care, Cambridge University Press (CUP), Vol. 12, No. 2 ( 1996), p. 299-324
    Abstract: The scientific evidence for clinical effectiveness of transcutaneous electrical nerve stimulation (TENS) for treatment of acute, chronic, and labor and delivery pain is assessed in this paper, and it is concluded that there is little evidence for other than a limited use of TENS. The utilization of TENS in Canadian hospitals and payments for TENS services are addressed. Some practicalities regarding the use and assessment of health technologies are discussed.
    Type of Medium: Online Resource
    ISSN: 0266-4623 , 1471-6348
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 1996
    detail.hit.zdb_id: 2020486-3
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  • 3
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 1995
    In:  International Journal of Technology Assessment in Health Care Vol. 11, No. 1 ( 1995), p. 93-101
    In: International Journal of Technology Assessment in Health Care, Cambridge University Press (CUP), Vol. 11, No. 1 ( 1995), p. 93-101
    Abstract: Canada comprises 10 provinces and 2 territories. The Constitution assigns responsibility for the provision of health services in the provinces to provincial governments. Over the past 5 years, provincial governments have identified technology assessment as a priority. This paper describes an initiative taken by the government of the province of Alberta to develop a health technology assessment program for that province.
    Type of Medium: Online Resource
    ISSN: 0266-4623 , 1471-6348
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 1995
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  • 4
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 1999
    In:  International Journal of Technology Assessment in Health Care Vol. 15, No. 1 ( 1999-01), p. 236-242
    In: International Journal of Technology Assessment in Health Care, Cambridge University Press (CUP), Vol. 15, No. 1 ( 1999-01), p. 236-242
    Abstract: The need for better communication and collaboration between health technology assessment agencies led to the formation of an International Network of Agencies for Health Technology Assessment (INAHTA). The network now comprises 27 agencies and has been successful in improving exchange of information and in undertaking joint health technology assessment projects. Issues for the future include possible changes to criteria for membership and identification of resources for more extensive programs.
    Type of Medium: Online Resource
    ISSN: 0266-4623 , 1471-6348
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 1999
    detail.hit.zdb_id: 2020486-3
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  • 5
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2011
    In:  BMC Dermatology Vol. 11, No. 1 ( 2011-12)
    In: BMC Dermatology, Springer Science and Business Media LLC, Vol. 11, No. 1 ( 2011-12)
    Type of Medium: Online Resource
    ISSN: 1471-5945
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2011
    detail.hit.zdb_id: 2059863-4
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  • 6
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 1999
    In:  International Journal of Technology Assessment in Health Care Vol. 15, No. 2 ( 1999-05), p. 297-303
    In: International Journal of Technology Assessment in Health Care, Cambridge University Press (CUP), Vol. 15, No. 2 ( 1999-05), p. 297-303
    Abstract: Biomedical databases are an important source of information for health technology assessment. However, there is considerable variation in the costs of accessing commercial databases. We sought to measure the quality, amount of overlap, and costs of information retrieved from two of the main database sources — MEDLINE and EMBASE. Librarians at two health technology assessment agencies ran a total of eight literature searches on various medical technologies, using both databases. All search results were independently reviewed by two researchers. The researchers were asked to identify relevant references and to rank each of these according to a level of evidence scale. The results were tabulated to show the number of references identified by each database, the number of relevant references ranked by level of evidence, and the number of these references that were unique to one or the other database. The cost of retrieving references from each source was also calculated. Each database contained relevant references not available in the other. Because of the longer time lag for indexing in MEDLINE, many of the references that originally appeared to be unique to EMBASE were subsequently available in MEDLINE as well. Since our study was conducted, MEDLINE has been made available worldwide, free of charge, via the Internet. Hence, the cost difference between the databases is now even greater. However, notwithstanding the costs, it appears that literature searches that rely on only one or the other database will inevitably miss pertinent information.
    Type of Medium: Online Resource
    ISSN: 0266-4623 , 1471-6348
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 1999
    detail.hit.zdb_id: 2020486-3
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  • 7
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2006
    In:  International Journal of Technology Assessment in Health Care Vol. 22, No. 1 ( 2006-01), p. 119-129
    In: International Journal of Technology Assessment in Health Care, Cambridge University Press (CUP), Vol. 22, No. 1 ( 2006-01), p. 119-129
    Abstract: Objectives: This study sought to examine the safety, efficacy, and economic implications of the use of cerebral protection devices during carotid artery angioplasty and stenting (CAS) in high-risk patients with severe carotid artery disease (CAD). Methods: A comprehensive search for peer- and non–peer-reviewed studies that compared carotid endarterectomy (CEA) or CAS without cerebral protection to CAS with cerebral protection and appeared in the English language literature between January 1990 and January 2005 was completed. Information from studies identified was extracted using a common data abstraction form and then critically appraised against published quality assessment criteria. Results: Of the eight studies found, six provided information on technical or procedural success rates, with values ranging from 95.6 percent to 100 percent. Three of the four studies comparing groups of patients who received CAS with cerebral protection with those who received only CAS reported a non-statistically significantly higher 30-day incidence of death and stroke (major or minor) in the latter group. None of the three studies comparing CAS with cerebral protection to CEA demonstrated a statistically significant difference in the 30-day incidence of death, major stroke, or myocardial infarction between treatment groups. No economic analyses were found. Conclusions: In high-risk patients with severe CAD, the evidence suggests that CAS with cerebral protection may offer a safe and efficacious alternative to CEA, reducing the risk of embolic peri-procedural complications associated with CAS to acceptable levels.
    Type of Medium: Online Resource
    ISSN: 0266-4623 , 1471-6348
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2006
    detail.hit.zdb_id: 2020486-3
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  • 8
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2018
    In:  International Journal of Technology Assessment in Health Care Vol. 34, No. S1 ( 2018), p. 130-131
    In: International Journal of Technology Assessment in Health Care, Cambridge University Press (CUP), Vol. 34, No. S1 ( 2018), p. 130-131
    Abstract: Many population-based studies identify surgical complications using hospital discharge abstract databases (DAD). With DAD, however, complications occurring after the discharge date cannot be followed up. This study used physician claims data to identify the complications of partial nephrectomy, and to compare the rates of complications of open, laparoscopic, and robot-assisted nephrectomies. Methods: Physician claims, DAD, and ambulatory care data from April 2003 to March 2016 were provided by Alberta Health. DAD and ambulatory care data were used to extract information on patients with kidney cancer who underwent partial nephrectomy. All physician claims within 30 days before and after surgery for the cohort were extracted. The numbers of the same International Classification of Diseases, Ninth Revision (ICD-9), codes before and after surgery were compared. If a number increased after surgery, this diagnosis was initially identified as a complication. All diagnoses with neoplasms were excluded. The incidence rates of complications for the three surgery groups were calculated. Chi-squared tests were conducted for the following nephrectomy comparisons: laparoscopic versus open; robot-assisted versus open; and robot-assisted versus laparoscopic. Results: A total of 1,890 kidney cancer patients had partial nephrectomies. Among them, 1,080, 411, and 399 had open, laparoscopic, and robot-assisted nephrectomies, respectively. One patient who had two different nephrectomies on the same day was excluded from analysis. The robot-assisted group had lower rates of digestive complications (ICD-9: 537–578, 787, 789, 998.6) and infections (ICD-9: 004–041, 998.5) than the open group, and higher rates of genitourinary complications (ICD-9: 584–599, 788, 997.5) than the laparoscopy group. The robot-assisted group had lower rates than the open group for most of the complication categories, but the differences were not statistically significant. Conclusions: Robot-assisted surgery appears to be superior to open surgery, but no better than laparoscopic surgery, in terms of minimizing the risk of complications following partial nephrectomy.
    Type of Medium: Online Resource
    ISSN: 0266-4623 , 1471-6348
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2018
    detail.hit.zdb_id: 2020486-3
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  • 9
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2018
    In:  International Journal of Technology Assessment in Health Care Vol. 34, No. S1 ( 2018), p. 164-164
    In: International Journal of Technology Assessment in Health Care, Cambridge University Press (CUP), Vol. 34, No. S1 ( 2018), p. 164-164
    Abstract: In Canada, reimbursement recommendations on drugs for common and rare indications (for example, orphan drugs) are made through the pan-Canadian Oncology Drug Review (pCODR) and the Common Drug Review (CDR). However, some stakeholders have called for a separate mechanism for orphan drugs, arguing that existing processes place too much weight on their high price tags. The purpose of this study was to examine factors associated with positive recommendations on drugs for rare diseases. Methods: Information was extracted from CDR and pCODR recommendations on drugs for diseases (prevalence of less than 1 in 2,000) up to April 2018. Univariate and multivariate logistic regression models were applied to explore the influence of the following variables on recommendations: year; prevalence; clinical safety and effectiveness (safety, quality of life, symptoms, surrogate outcomes, and survival); quality of evidence (availability of comparative data, external validity, and bias); unmet need; treatment cost; and incremental cost-effective ratio (ICER). Two-way interactions were also tested. Results: Of 128 recommendations, fifty-four (77 percent) and forty (69 percent) were positive for cancer and non-cancer indications, respectively. For cancer indications, all submissions reporting meaningful improvements in surrogate, quality of life, and survival outcomes were significantly more likely to have a positive recommendation. Submissions showing a lack of external validity were significantly less likely to receive a positive recommendation. For non-cancer indications, more recent submissions and those presenting no safety issues were associated with positive recommendations. Prevalence, treatment cost, and ICER were not determinants of positive or negative recommendations. Conclusions: For both cancer and non-cancer orphan drugs, impact on clinical safety and effectiveness, rather than cost, appears to be a key factor in the formulation of recommendations.
    Type of Medium: Online Resource
    ISSN: 0266-4623 , 1471-6348
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2018
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  • 10
    Online Resource
    Online Resource
    Health Affairs (Project Hope) ; 2001
    In:  Health Affairs Vol. 20, No. 3 ( 2001-05), p. 92-103
    In: Health Affairs, Health Affairs (Project Hope), Vol. 20, No. 3 ( 2001-05), p. 92-103
    Type of Medium: Online Resource
    ISSN: 0278-2715 , 1544-5208
    Language: English
    Publisher: Health Affairs (Project Hope)
    Publication Date: 2001
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