In:
RSC Advances, Royal Society of Chemistry (RSC), Vol. 12, No. 16 ( 2022), p. 9763-9772
Abstract:
A facile CuBr 2 induced radical relay addition/cyclization of activated alkenes with substituted-thiosulfonates has been achieved, leading to a broad range of sulfonated indolo[2,1- a ]isoquinolines and benzimidazo[2,1- a ]isoquinolin-6(5 H )-ones in moderate to good yields. In particular, some compounds exhibit bioactivity against cancer cell lines. This protocol shows advantages of low-cost, base-free, simple operation, and broad functional group tolerance.
Type of Medium:
Online Resource
ISSN:
2046-2069
Language:
English
Publisher:
Royal Society of Chemistry (RSC)
Publication Date:
2022
detail.hit.zdb_id:
2623224-8
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