In:
Cancer Epidemiology, Biomarkers & Prevention, American Association for Cancer Research (AACR), Vol. 30, No. 10 ( 2021-10-01), p. 1799-1806
Abstract:
American Indian and Alaska Native (AI/AN) populations have experienced regional variation and disparities in colorectal cancer incidence rates. Methods: We examined colorectal cancer incidence (2013–2017) and colorectal cancer incidence trends (1999–2017) among AI/AN persons. Incidence data were linked to Indian Health Service enrollment records, and analyses were restricted to Purchased/Referred Care Delivery Areas. Incidence rates of colorectal cancer among AI/AN and White persons were analyzed in six geographic regions; Hispanic persons were excluded. Incidence trends were analyzed using linear modeling. Results: During 2013–2017, colorectal cancer incidence was 41% higher among AI/AN than among White persons. AI/AN incidence rates per 100,000 varied regionally from 34.4 in the East to 96.1 in Alaska. Compared with White persons, AI/AN persons had higher colorectal cancer incidence rates among all age strata and were more likely to have late-stage diagnoses. Incidence rate trends indicated significant increases among both AI/AN and White persons ages & lt;50 years and among AI/AN persons ages 50–64 years. The colorectal cancer incidence rate trend increased among AI/AN persons in the Southwest. Conclusions: The disparity of colorectal cancer incidence rates between AI/AN and White persons has widened since 2005–2009. AI/AN populations have higher colorectal cancer incidence compared with White populations, especially in the Alaska region. Impact: Our finding of increased colorectal cancer incidence disparities suggests that enhanced screening efforts and culturally appropriate clinical and public health interventions are needed among AI/AN persons overall, and especially in regions and age groups in which colorectal cancer rates are increasing.
Type of Medium:
Online Resource
ISSN:
1055-9965
,
1538-7755
DOI:
10.1158/1055-9965.EPI-21-0343
Language:
English
Publisher:
American Association for Cancer Research (AACR)
Publication Date:
2021
detail.hit.zdb_id:
2036781-8
detail.hit.zdb_id:
1153420-5
Permalink