In:
Annals of Medicine & Surgery, Ovid Technologies (Wolters Kluwer Health)
Abstract:
This case report presents an intriguing instance of a 35-year-old non-smoker female who exhibited a convergence of acute necrotizing pneumonia (ANP) and squamous cell carcinoma (SCC), two distinct pulmonary conditions. ANP involves severe lung infection and tissue necrosis, while SCC is a non-small cell lung carcinoma originating from the bronchial epithelium. Such a unique combination in a non-smoker female patient emphasizes the intricate interplay of diverse pulmonary pathologies and the importance of comprehensive diagnostic evaluation and effective patient management strategies. Case presentation: The patient’s symptoms include fever, pain, cough, and sporadic hemoptysis. Initial imaging suggested ANP due to a multilobulated necrotic lung mass. Despite empirical antibiotic therapy, no improvement occurred, prompting further investigation. PET-CT revealed intense FDG avidity in the lesion. A CT-guided Tru-cut biopsy confirmed non-small cell carcinoma with squamous differentiation in the necrotic mass. Clinical discussion: ANP is a severe manifestation of pneumonia, predominantly affecting young, healthy individuals, while SCC, commonly linked to smoking, presents as non-small cell lung carcinoma. Overlapping symptoms and radiological findings complicate diagnosis. Early diagnosis and appropriate management are crucial for both conditions to prevent progression and complications. Conclusion: This case highlights the significance of precise diagnosis and adaptable treatment approaches. The coexistence of ANP and SCC in a non-smoker female patient underscores the necessity of meticulous diagnostic evaluation and personalized treatment strategies. The scarcity of such presentations emphasizes the need for further research to comprehend the mechanisms underlying these occurrences.
Type of Medium:
Online Resource
ISSN:
2049-0801
DOI:
10.1097/MS9.0000000000001353
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2023
detail.hit.zdb_id:
2745440-X
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