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  • 1
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    Online Resource
    Peculiarities of diagnostics and treatment of patients with recurrent myocardial infarction
    Medical Informational Agency Publishers ; 2016
    In:  Clinical Medicine (Russian Journal) Vol. 94, No. 3 ( 2016-04-15), p. 183-188
    Details
    In: Clinical Medicine (Russian Journal), Medical Informational Agency Publishers, Vol. 94, No. 3 ( 2016-04-15), p. 183-188
    Abstract: The aim of the study was to evaluate the efficiency of invasive strategies for the treatment of 306 patients with recurrent myocardial infarction (IM) admitted to our clinic in 2003-2007. We compared the results of three approaches: various forms of transdermal coronary interventions (TDI) including delayed (24-72 hr) ones (n=30), surgical myocardial revascularization within 8-12 weeks after the onset of recurrent myocardial infarction (n=25), and conservative therapy (n=251). Overall cardiovascular lethality was estimated during 5 years in 101 patients. It was shown that recurrent myocardial infarction is a predictor of high risk of death associated, in the absence of reperfusion therapy, with high intra-hospital and long-term lethality. TDI soon after recurrent IM does not exclude possibility of its application in a later period. Various interventions including delayed ones markedly decrease the frequency of complications and lethal outcome that remains high in their absence. At the same time, severe lesions of the coronary bed in many patients with recurrent MI limit the possibility of using TDI and should be regarded as indications for planned surgical myocardial revascularization. Coronary bypass surgery after myocardial scarring prevents progress of left ventricle dysfunction, improves its contractility and increases life expectancy. Enhanced availability of reperfusion strategies in the form of TDI and/or delayed surgical myocardial revascularization opens up new possibilities for effective treatment of recurrent MI.
    Type of Medium: Online Resource
    ISSN: 2412-1339 , 0023-2149
    URL: Issue
    URL: Article
    DOI: 10.18821/0023-2149-2016-94-3
    DOI: 10.18821/0023-2149-2016-94-3-183-188
    Language: Unknown
    Publisher: Medical Informational Agency Publishers
    Publication Date: 2016
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  • 2
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    Online Resource
    Inflammatory continuum in the pathogenesis of atrial fibrillation after coronary bypass surgery
    Silicea - Poligraf, LLC ; 2022
    In:  Cardiovascular Therapy and Prevention Vol. 21, No. 3 ( 2022-01-26), p. 3094-
    Details
    In: Cardiovascular Therapy and Prevention, Silicea - Poligraf, LLC, Vol. 21, No. 3 ( 2022-01-26), p. 3094-
    Abstract: Atrial fibrillation (AF) after coronary bypass surgery is recorded in 20- 60% of patients and increase the early and long-term postoperative mortality. The aim of the review is to analyze the studies on causal relationships between damaging factors and the development of myocardial inflammation at each stage of surgical treatment in patients with multivessel coronary artery disease. In the review, myocardial inflammation is considered from the point of view of a continuum  — a chronic process that originates from the coronary endothelium damage and continuously proceeds within the AF pathogenesis after coronary bypass surgery. For the first time, the concept of inflammatory continuum for postoperative AF is introduced. The review discusses the main and latest laboratory and instrumental markers of local and systemic inflammatory response, which are informative in terms of severity and promising for improving approaches to the diagnosis and prevention of postoperative AF. The review was prepared using available materials from Russian and foreign library databases (PubMed, Medline, Web of Science and Cochrane Library). The search depth was 〉 25 years since 1996. Based on the analysis of available studies, we concluded that inflammation is not just evidence of AF, but plays a causal role in its pathogenesis at each stage of surgical myocardial revascularization.
    Type of Medium: Online Resource
    ISSN: 2619-0125 , 1728-8800
    URL: Issue
    URL: Article
    DOI: 10.15829/1728-8800-2022-3
    DOI: 10.15829/1728-8800-2022-3094
    Language: Unknown
    Publisher: Silicea - Poligraf, LLC
    Publication Date: 2022
    detail.hit.zdb_id: 3032202-9
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  • 3
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    Surgical Remodeling of the Left Ventricle in Patients with Post-Infarction Dilation and Heart Failure
    The Scientific and Practical Society of Emergency Medicine Physicians ; 2022
    In:  Russian Sklifosovsky Journal "Emergency Medical Care" Vol. 11, No. 1 ( 2022-04-07), p. 50-58
    Details
    In: Russian Sklifosovsky Journal "Emergency Medical Care", The Scientific and Practical Society of Emergency Medicine Physicians, Vol. 11, No. 1 ( 2022-04-07), p. 50-58
    Abstract: INTRODUCTION The cause of heart failure in patients with coronary artery disease after anterior myocardial infarction may be dilatation of the cavity of the left ventricle (LV) with subsequent unfavorable course of the disease. In the case of early reperfusion, which prevents transmural myocardial necrosis, the damaged segment more often becomes akinetic than dyskinetic. Surgical remodeling of the left ventricle (SRLV) is aimed at reducing the volume and restoring its elliptical shape by eliminating scars in the akinetic and/or dyskinetic segments. AIM OF STUDY To evaluate the survival of patients with chronic heart failure (CHF) who had anterior wall myocardial infarction in the early and late periods after surgical remodeling of the left ventricle, in combination with coronary bypass grafting and/or interventions on the mitral valve. MATERIAL AND METHODS The study included 99 patients with coronary artery disease (CAD) who had myocardial infarction of the anterior LV wall and with severe heart failure, who underwent surgical LV remodeling in the period from 2002 to 2020. The analysis of early and long-term results was carried out. The risk factors influencing lethality were determined. The mean age of the patients was 56.0±10.2 years (from 23 to 81 years). The vast majority of patients (90%) were men. LV ventriculoplasty was combined with coronary bypass grafting in 97 (98%) patients, with mitral valve repair in 2 (2%) patients, with mitral valve replacement in 2 (2%) patients. RESULTS In the early postoperative period, all patients showed an improvement in global LV systolic function. The ejection fraction (EF) of the left ventricle increased from the average preoperative average value of 34.2±3.7% to 43±4.2% in the postoperative period (р 〈 0,001). Left ventricular end systolic volume index (LVESV) decreased from 71.4±15.3 ml/m 2 to 43.8±9.6 ml/m 2 , respectively (р 〈 0,001). In the early postoperative period, 5 (5%) patients used the following means of mechanical hemodynamic support: intra-aortic balloon pump (IABP), non-implantable device for temporary support of the left ventricle (LVAD) and extracorporeal membrane oxygenation (ECMO). The 30-day mortality rate after LVESV was 6%. Prior to surgery, all patients had NYHA functional class (FC) III or IV. In the postoperative period, all patients experienced regression of heart failure symptoms and improved exercise tolerance. NYHA functional class improved to I and II in 100% of cases. Using univariate analysis, it was possible to determine that EF ≤30%, LVESV ≥80 ml/m 2 and pulmonary artery pressure (PAP) 〉 60 mm Hg. were risk factors for hospital mortality. The overall fifteen-year survival rate was 59.8±0.13%. The absence of readmission to the hospital due to recurrent angina pectoris, mitral valve dysfunction and progression of heart failure (HF) was 72% among surviving patients. CONCLUSION Surgical remodeling reduces the volume of the dilated left ventricle and restores its elliptical shape in patients with CAD after anterior myocardial infarction. The results of our study demonstrate an improvement in LV systolic function in all patients in the early postoperative period and low mortality, an acceptable fifteen-year survival rate, and a low readmission rate due to the progression of chronic heart failure (CHF).
    Type of Medium: Online Resource
    ISSN: 2541-8017 , 2223-9022
    URL: Article
    DOI: 10.23934/2223-9022-2022-11-1-50-58
    Language: Unknown
    Publisher: The Scientific and Practical Society of Emergency Medicine Physicians
    Publication Date: 2022
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  • 4
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    Online Resource
    Inhospital changes of left ventricular diastolic function in patients undergoing coronary bypass surgery
    Silicea - Poligraf, LLC ; 2022
    In:  Russian Journal of Cardiology Vol. 27, No. 8 ( 2022-08-03), p. 4948-
    Details
    In: Russian Journal of Cardiology, Silicea - Poligraf, LLC, Vol. 27, No. 8 ( 2022-08-03), p. 4948-
    Abstract: Aim.  To evaluate changes of left ventricular (LV) diastolic function in patients with multivessel coronary artery disease before coronary artery bypass grafting (CABG) and in the early postoperative period (7-10 days), as well as to assess the relation- ship between diastolic LV dysfunction and postoperative atrial fibrillation (POAF). Material and methods. This original prospective study of included 50 patients undergoing CABG at the Cardiac Surgery Unit № 1 of the N. V. Sklifosovsky Research Institute for Emergency Medicine from December 2020 to December 2021. All patients underwent standard echocardiography before and after surgery. Diastolic function was assessed using the following parameters: septal mitral annulus velocity (e’septal), lateral mitral annulus velocity (e’lateral), the ratio of the peak early transmitral velocity to peak early diastolic velocity of the mitral annulus movement (E/e’), left atrial volume index (ml/m 2 ), peak tricuspid regurgitation velocity (m/s), the ratio of the peak early to late filling velocity (E/A). Results. After CABG, 35 patients maintained sinus rhythm in the early postoperative period (group 1), while 15 patients had POAF (group 2). According to echocardiography, type 1 diastolic dysfunction prevailed in both groups; types 2 and 3 LV diastolic dysfunction were not identified. Among the parameters characterizing myocardial relaxation, in group 1 after CABG, a significant increase in the peak E (p=0,001) was noted, and due to this, the normalization of the E/A ratio was recorded (p 〈 0,0001). An increase in e’lateral (p=0,05) was also revealed, in connection with which an increase in the E/e’ (p=0,02) was noted. In the group of patients with POAF, such changes were not detected. Left atrial volume index (ml/ m 2 ) was significantly higher in the POAF group (p=0,02). Conclusion. Surgical myocardial revascularization has a positive effect on LV diastolic function. Improvement in LV diastolic function after CABG may be a sign of the restoration of hibernating myocardium function, while the absence of LV diastolic function improvement, together with left atrial dilatation, may be predictors of early POAF.
    Type of Medium: Online Resource
    ISSN: 2618-7620 , 1560-4071
    URL: Issue
    URL: Article
    DOI: 10.15829/1560-4071-2022-8
    DOI: 10.15829/1560-4071-2022-4948
    Language: Unknown
    Publisher: Silicea - Poligraf, LLC
    Publication Date: 2022
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  • 5
    Online Resource
    Online Resource
    Giant postinfarction posterolateral left ventricular aneurysm, complicated by mitral insufficiency
    IPO Association of Transplantologists ; 2023
    In:  Transplantologiya. The Russian Journal of Transplantation Vol. 15, No. 1 ( 2023-03-18), p. 46-60
    Details
    In: Transplantologiya. The Russian Journal of Transplantation, IPO Association of Transplantologists, Vol. 15, No. 1 ( 2023-03-18), p. 46-60
    Abstract: Ischemic heart disease holds the leading position in the structure of cardiovascular diseases. Early reperfusion therapy for acute myocardial infarction led to a decrease in mortality and severe complications of coronary artery disease. Despite advances in the treatment of coronary artery disease, dilatation and remodeling of the left ventricle develop in 20% of patients who have had a heart attack, leading to mitral insufficiency and systolic dysfunction of the left ventricle. Aneurysm of the left ventricle is a delayed severe complication of myocardial infarction, which significantly worsens the prognosis. Large aneurysms of the left ventricle cause progressive dilatation of the left ventricle, its volumetric overload with an increase in wall tension in the non-infarction zone, decreased functional characteristics of the left ventricle, thrombosis in the aneurysm cavity, life-threatening arrhythmias, and sudden death. Postinfarction left ventricular remodeling can lead to secondary mitral regurgitation, which is an independent predictor of mortality in the longterm period. Surgical treatment of coronary heart disease and its complications is one of the main problems of modern cardiovascular surgery.
    Type of Medium: Online Resource
    ISSN: 2542-0909 , 2074-0506
    URL: Issue
    URL: Article
    DOI: 10.23873/2074-0506-2017-0-7
    DOI: 10.23873/2074-0506-2023-15-1-46-60
    Language: Unknown
    Publisher: IPO Association of Transplantologists
    Publication Date: 2023
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  • 6
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    The role of atherosclerotic coronary arteries lesions in development of new-onset atrial fibrillation after coronary artery bypass surgery
    APO Society of Specialists in Heart Failure ; 2021
    In:  Kardiologiia Vol. 61, No. 12 ( 2021-12-31), p. 41-48
    Details
    In: Kardiologiia, APO Society of Specialists in Heart Failure, Vol. 61, No. 12 ( 2021-12-31), p. 41-48
    Abstract: Aim    To study the relationship between the type of circulation, severity and localization of atherosclerotic damage of coronary arteries, results of laboratory and instrumental tests, and historical data in patients with multivascular coronary lesions and atrial fibrillation (AF) that developed after coronary bypass surgery. Material and methods    This was a novel, retrospective study of data of patients after elective coronary bypass surgery at the Cardiac Surgery Department #1 of the N.V. Sklifosofsky Research Institute of Emergency Care from December, 2018 through December, 2020. The study included 100 patients. The main group consisted of 20 patients whose early postoperative period (first 7 days after surgery) was complicated with postoperative atrial fibrillation (POAF) (mean age, 65.15±9.7 years). The comparison group included 80 patients without the POAF complication during the early postoperative period (mean age, 62.0±9.16 years). Prior to the coronary bypass surgery, all patients underwent clinical, laboratory, and instrumental examination. Based on data of selective coronary angiography, localization, severity of coronary atherosclerotic damage (according to angiographic classification), number of affected arteries, and the type of circulation were taken into account. Results    Intergroup differences in the incidence and localization of myocardial infarctions in history, severity of arterial hypertension in history, class of chronic heart failure (according to the New York Heart Association, NYHA, classification), and heart rate were absent. 100 % of patients had left atrial (LA) dilatation not correlated with the development of AF in the early postoperative period. According to data of coronary angiography, there was no statistically significant association between the type of circulation and the development of POAF. The right type of myocardial blood supply prevailed in patients of both groups. There was no correlation between the severity and localization of coronary atherosclerotic lesions and the development of AF in the early postoperative period. Conclusion    The development of AF following coronary bypass surgery was not associated with features of coronary atherosclerotic lesions, which may indicate active development of inter- and intra-systemic anastomoses in patients with long-term history of chronic coronary atherosclerosis.  
    Type of Medium: Online Resource
    ISSN: 2412-5660 , 0022-9040
    URL: Article
    DOI: 10.18087/cardio.2021.12.n1541
    Language: Unknown
    Publisher: APO Society of Specialists in Heart Failure
    Publication Date: 2021
    detail.hit.zdb_id: 3005439-4
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  • 7
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    Emergency endovascular treatment of cardioembolic stroke in the early post-infarction period with subsequent direct myocardial revascularization
    Reaviz Medical University ; 2023
    In:  Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH) Vol. 13, No. 4 ( 2023-09-14), p. 113-120
    Details
    In: Bulletin of the Medical Institute "REAVIZ" (REHABILITATION, DOCTOR AND HEALTH), Reaviz Medical University, Vol. 13, No. 4 ( 2023-09-14), p. 113-120
    Abstract: Introduction. Ischemic stroke (IS) remains one of the significant problems of modern medicine to this day. Cardioembolic stroke (CEI) accounts for 20 % of all cases of IS and is characterized by acuteness, severity of the disease and high mortality. Aim of study. An observation is presented in patient Sh., 51 years old, who was urgently transferred from another medical institution on the 3rd day after the development of acute recurrent anterior myocardial infarction with ST segment elevation complicated by early post-infarction angina pectoris. During the additional examination, in addition to severe multifocal atherosclerosis and multivessel coronary artery disease, a floating thrombus in the cavity of the left ventricle was detected. At the stage of preparing the patient for coronary artery bypass grafting, the patient developed stroke. Thrombextraction from the basilar artery (BA) was performed urgently. As a result, a complete regression of neurological symptoms was achieved. This made it possible to continue the preparation and successfully perform coronary artery bypass grafting. The patient was discharged on the 10th day after the operation, the entire hospitalization period was 28 bed-days. Discussion . In the presented case, a patient with a clinic of unstable angina pectoris, severe multifocal atherosclerosis, and multivessel coronary artery disease was in a specialized multidisciplinary hospital at the time of the development of stroke. The well-coordinated work of the multidisciplinary team, the possibility of performing thromboaspiration in the shortest possible time allowed not only to save the patient's life and achieve complete regression of neurological symptoms, but also to improve the quality of life through surgical treatment of coronary heart disease.
    Type of Medium: Online Resource
    ISSN: 2782-1579 , 2226-762X
    URL: Article
    DOI: 10.20340/vmi-rvz.2023.4.CASE.3
    Language: Unknown
    Publisher: Reaviz Medical University
    Publication Date: 2023
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  • 8
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    The Effect of Fatty Acid Ethyl Esters Concentration on the Kinematic Viscosity of Biodiesel Fuel
    American Chemical Society (ACS) ; 2015
    In:  Journal of Chemical & Engineering Data Vol. 60, No. 11 ( 2015-11-12), p. 3404-3413
    Details
    In: Journal of Chemical & Engineering Data, American Chemical Society (ACS), Vol. 60, No. 11 ( 2015-11-12), p. 3404-3413
    Type of Medium: Online Resource
    ISSN: 0021-9568 , 1520-5134
    URL: Article
    DOI: 10.1021/acs.jced.5b00683
    Language: English
    Publisher: American Chemical Society (ACS)
    Publication Date: 2015
    detail.hit.zdb_id: 1491128-0
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  • 9
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    Biodiesel fuel. Part III. Quantum chemical research and simulation of the process
    Kazan State Power Engineering University ; 2023
    In:  Power engineering: research, equipment, technology Vol. 25, No. 1 ( 2023-04-23), p. 24-44
    Details
    In: Power engineering: research, equipment, technology, Kazan State Power Engineering University, Vol. 25, No. 1 ( 2023-04-23), p. 24-44
    Abstract: THE PURPOSE. The purpose of this work was to use the associated paradigm for a correct quantum-chemical description of non-catalytic and catalytic supercritical fluid processes of transesterification of triglycerides with alcohols and hydrolysis of triglycerides and to model a one-stage process for obtaining biodiesel fuel, carried out under supercritical fluid conditions with its subsequent scaling to the commercial level. METHODS. The Gaussian09 software product was used to describe quantum chemical studies. The process modeling was carried out using the ASPEN Plus® v2006 software product. The behavior of thermodynamic systems at high temperatures and pressures is modeled using "RK ASPEN EOS". For modeling processes carried out at low pressures, mathematical models UNIQUAC and UNIFAC-LL were used. The scaling of the process was carried out in the VMGSim program. RESULTS. The third part of the review focuses on the quantum-chemical modeling of the transesterification reaction carried out under supercritical fluid conditions. It is shown that taking into account the associative paradigm makes it possible to obtain calculated reaction rate constants that agree in order with the experimental values. And also an analysis was carried out and the results of modeling the process of obtaining biodiesel fuel and scaling it to a commercial level, with a capacity of up to 9000 tons / year, were presented. CONCLUSION. The conducted analysis showed that biodiesel fuel can be a competitive fuel in our and the world market.
    Type of Medium: Online Resource
    ISSN: 2658-5456 , 1998-9903
    URL: Article
    DOI: 10.30724/1998-9903-2023-25-1-24-44
    Language: Unknown
    Publisher: Kazan State Power Engineering University
    Publication Date: 2023
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