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  • 1
    Online Resource
    Online Resource
    Playing it cool: Characterizing social play, bout termination, and candidate play signals of juvenile and infant Tibetan macaques (Macaca thibetana) 
    Zoological Research ; 2018
    In:  Zoological Research Vol. 39, No. 4 ( 2018), p. 272-283
    Details
    In: Zoological Research, Zoological Research, Vol. 39, No. 4 ( 2018), p. 272-283
    Type of Medium: Online Resource
    ISSN: 2095-8137
    URL: Article
    DOI: 10.24272/j.issn.2095-8137.2018.048
    Language: English
    Publisher: Zoological Research
    Publication Date: 2018
    detail.hit.zdb_id: 2196960-7
    SSG: 12
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  • 2
    Online Resource
    Online Resource
    Evaluation of Laparoscopic‐Assisted Ovariohysterectomy for Treatment of Canine Pyometra
    Wiley ; 2013
    In:  Veterinary Surgery Vol. 42, No. 5 ( 2013-06), p. 572-578
    Details
    In: Veterinary Surgery, Wiley, Vol. 42, No. 5 ( 2013-06), p. 572-578
    Abstract: To describe a technique for treating pyometra in dogs using a 3‐portal laparoscopic‐assisted ovariohysterectomy (LAOVH) and evaluate outcome. Study Design Retrospective case series. Animals Dogs (n = 12). Methods Dogs with open or closed‐cervix pyometra with moderately sized (1–4 cm) uterine horn diameters based on preoperative ultrasonography and no evidence of perforation were included in the study. A 3‐portal technique for LAOVH was used. A wound retraction device was inserted into the caudal portal after enlargement of the incision to 3–4 cm to simplify removal of the uterus with minimal tension. Results Twelve dogs (median weight, 23.3 kg; range, 2.1–46.0 kg) met the inclusion criteria. Median uterine diameter was 3.0 cm (range, 1.2–4.0 cm). Median surgical time for LAOVH was 107 minutes (range, 82–120 minutes). Complications included mild hemorrhage from the uterine vessels in 1 dog during uterine removal through the wound retraction device and intra‐abdominal uterine rupture in 1 dog which necessitated conversion to an open approach. All dogs recovered from surgery and were discharged. Conclusions LAOVH can be used for treatment of select cases of canine pyometra. Careful case selection is mandatory to improve success and minimize conversion to an open approach. Gentle handling of the reproductive organs is imperative to avoid iatrogenic uterine rupture.
    Type of Medium: Online Resource
    ISSN: 0161-3499 , 1532-950X
    URL: Issue
    URL: Article
    DOI: 10.1111/vsu.v42.5
    DOI: 10.1111/j.1532-950X.2013.12012.x
    Language: English
    Publisher: Wiley
    Publication Date: 2013
    detail.hit.zdb_id: 1491071-8
    SSG: 22
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  • 3
    Online Resource
    Online Resource
    Experimental and Clinical Evaluation of Transperitoneal Laparoscopic Ureteronephrectomy in Dogs
    Wiley ; 2013
    In:  Veterinary Surgery Vol. 42, No. 5 ( 2013-06), p. 565-571
    Details
    In: Veterinary Surgery, Wiley, Vol. 42, No. 5 ( 2013-06), p. 565-571
    Abstract: To report a surgical technique for transperitoneal laparoscopic ureteronephrectomy (TLU) in dogs and describe complications and outcome in a cohort of dogs. Study Design Experimental study and case series. Animals Purpose‐bred research dogs (n = 3) and canine clinical cases (9). Methods In 11 of 12 dogs, a 3 port laparoscopic approach was used and in 1 dog a 4‐port approach was used. Incision through the retroperitoneal space was followed by early dissection of the ureter to aid retraction and elevation of the renal hilus. Dissection was performed principally by use of a vessel‐sealing device. Ligation of the renal hilar vessels was accomplished using laparoscopic hemoclips. Experimental dogs were euthanatized and necropsied. Results In 3 experimental dogs, no intraoperative complications occurred and conversion to an open approach was unnecessary. Of 9 clinical cases, conversion to an open approach was required in 2 dogs, because of severe hydroureter obscuring observation in 1, and uncontrollable retroperitoneal hemorrhage in the other dog. In 1 dog hemorrhage from the renal capsule and renal vein was controlled laparoscopically. No other major complications occurred. All dogs were discharged. Conclusions Transperitoneal laparoscopic ureteronephrectomy is feasible in dogs although conversion to an open approach should be considered when uncontrollable hemorrhage is encountered or the view is obscured by anatomic alteration.
    Type of Medium: Online Resource
    ISSN: 0161-3499 , 1532-950X
    URL: Issue
    URL: Article
    DOI: 10.1111/vsu.v42.5
    DOI: 10.1111/j.1532-950X.2013.01092.x
    Language: English
    Publisher: Wiley
    Publication Date: 2013
    detail.hit.zdb_id: 1491071-8
    SSG: 22
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  • 4
    Online Resource
    Online Resource
    Evaluation of short-term outcome after lung lobectomy for resection of primary lung tumors via video-assisted thoracoscopic surgery or open thoracotomy in medium- to large-breed dogs
    American Veterinary Medical Association (AVMA) ; 2013
    In:  Journal of the American Veterinary Medical Association Vol. 243, No. 5 ( 2013-09-01), p. 681-688
    Details
    In: Journal of the American Veterinary Medical Association, American Veterinary Medical Association (AVMA), Vol. 243, No. 5 ( 2013-09-01), p. 681-688
    Abstract: Objective —To describe clinicopathologic features of dogs that underwent lung lobectomy for resection of primary lung tumors via video-assisted thoracoscopic surgery (VATS) or open thoracotomy (OT) and to compare short-term outcomes for dogs following these procedures. Design —Retrospective cohort study. Animals —46 medium- to large-breed dogs with primary lung tumors. Procedures —Medical records of dogs that underwent a lung lobectomy via VATS (n = 22) or OT (24) for resection of primary lung tumors between 2004 and 2012 were reviewed. Dogs were included if they weighed 〉 10 kg (22 lb) and resection of a primary lung tumor was confirmed histologically. Tumor volumes were calculated from preoperative CT scans where available. Surgical time, completeness of excision, time in the ICU, indwelling thoracic drain time, postoperative and total hospitalization time, incidence of major complications, and short-term survival rate were evaluated. Results —VATS was performed with a 3-port (n = 12) or 4-port (10) technique and 1-lung ventilation (22). In 2 of 22 (9%) dogs, VATS was converted to OT. All dogs survived to discharge from the hospital. There were no significant differences between the VATS and OT groups with regard to most variables. Surgery time was significantly longer for VATS than for OT (median, 120 vs 95 minutes, respectively). Conclusions and Clinical Relevance —In medium- to large-breed dogs, short-term outcomes for dogs that underwent VATS for lung lobectomy were comparable to those of dogs that underwent OT. Further studies are required to evaluate the effects of surgical approach on indices of postoperative pain and long-term outcomes.
    Type of Medium: Online Resource
    ISSN: 0003-1488
    URL: Article
    DOI: 10.2460/javma.243.5.681
    Language: Unknown
    Publisher: American Veterinary Medical Association (AVMA)
    Publication Date: 2013
    detail.hit.zdb_id: 2904887-4
    SSG: 22
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  • 5
    Online Resource
    Online Resource
    Comparison of perioperative morbidity and mortality rates in dogs with noninvasive adrenocortical masses undergoing laparoscopic versus open adrenalectomy
    American Veterinary Medical Association (AVMA) ; 2014
    In:  Journal of the American Veterinary Medical Association Vol. 245, No. 9 ( 2014-11-01), p. 1028-1035
    Details
    In: Journal of the American Veterinary Medical Association, American Veterinary Medical Association (AVMA), Vol. 245, No. 9 ( 2014-11-01), p. 1028-1035
    Abstract: Objective —To describe the clinicopathologic features of a cohort of dogs with adrenocortical masses that underwent laparoscopic adrenalectomy and to compare perioperative morbidity and mortality rates in these dogs with rates for dogs that underwent open adrenalectomy for resection of similarly sized (maximal diameter, ≤ 5 cm) adrenocortical masses. Design —Retrospective case series. Animals —48 client-owned dogs that underwent laparoscopic (n = 23) or open (25) adrenalectomy for noninvasive tumors (ie, tumors that did not invade the vena cava or other surrounding organs). Procedures —Medical records were reviewed. History, clinical signs, physical examination findings, clinicopathologic findings, imaging results, and surgical variables were recorded. A 3- or 4-port approach was used for laparoscopic adrenalectomy. Surgical time, perioperative complications, postoperative and overall hospitalization times, and perioperative deaths were recorded and compared between groups. Results —The surgical method for 1 dog was converted from a laparoscopic to an open approach. Perioperative death occurred in no dogs in the laparoscopic group and 2 dogs in the open adrenalectomy group. Surgical time was shorter for laparoscopic (median, 90 minutes; range, 40 to 150 minutes) than for open (median, 120 minutes; range, 75 to 195 minutes) adrenalectomy. Laparoscopic adrenalectomy was associated with shorter hospitalization time and more rapid discharge from the hospital after surgery, compared with the open procedure. Conclusions and Clinical Relevance —With careful patient selection, laparoscopic adrenalectomy was associated with a low complication rate and low conversion rate for resection of adrenocortical masses as well as shorter surgical and hospitalization times, compared with open adrenalectomy.
    Type of Medium: Online Resource
    ISSN: 0003-1488
    URL: Article
    DOI: 10.2460/javma.245.9.1028
    Language: Unknown
    Publisher: American Veterinary Medical Association (AVMA)
    Publication Date: 2014
    detail.hit.zdb_id: 2904887-4
    SSG: 22
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  • 6
    Online Resource
    Online Resource
    Evaluation of In Vivo Behavior of Ameroid Ring Constrictors in Dogs with Congenital Extrahepatic Portosystemic Shunts Using Computed Tomography
    Wiley ; 2014
    In:  Veterinary Surgery Vol. 43, No. 7 ( 2014-10), p. 834-842
    Details
    In: Veterinary Surgery, Wiley, Vol. 43, No. 7 ( 2014-10), p. 834-842
    Abstract: To evaluate the in vivo pattern of ameroid constrictor closure of congenital extrahepatic portosystemic shunts in dogs. Study Design Prospective study. Animals Dogs (n = 22) with congenital extrahepatic portosystemic shunts. Methods Contrast‐enhanced computed tomography was performed immediately before, and at least 8 weeks after placement of ameroid ring constrictors. Plastic‐encased ameroid constrictors were used in 17 dogs and metal constrictors in 5 dogs. Presence of residual flow through the portosystemic shunt, additional anomalous vessels, acquired shunts and soft tissue associated with the ameroid constrictor was recorded. Postoperative internal diameter was recorded for the 17 plastic constrictors. Correlations between internal diameter and pre‐ and postoperative serum protein concentration were analyzed. Results No ameroid constrictor closed completely: shunt occlusion was always dependent on soft tissue within the ameroid ring. Residual flow through the shunt was present in 4 dogs (18%), although this caused persistent elevation of shunt fraction in only 1 dog (dog 8). The change in ameroid constrictor internal diameter was not significantly correlated with serum protein concentration. Conclusions Complete shunt occlusion after AC placement is usually dependent on soft tissue reaction. Ameroid constrictors ≥5 mm diameter may not promote complete shunt occlusion.
    Type of Medium: Online Resource
    ISSN: 0161-3499 , 1532-950X
    URL: Issue
    URL: Article
    DOI: 10.1111/vsu.v43.7
    DOI: 10.1111/j.1532-950X.2014.12196.x
    Language: English
    Publisher: Wiley
    Publication Date: 2014
    detail.hit.zdb_id: 1491071-8
    SSG: 22
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  • 7
    Online Resource
    Online Resource
    Correlation Between Liver Volume, Portal Vascular Anatomy, and Hepatic Perfusion in Dogs With Congenital Portosystemic Shunt Before and After Placement of Ameroid Constrictors
    Wiley ; 2014
    In:  Veterinary Surgery Vol. 43, No. 8 ( 2014-11), p. 926-934
    Details
    In: Veterinary Surgery, Wiley, Vol. 43, No. 8 ( 2014-11), p. 926-934
    Abstract: To correlate changes in hepatic volume, hepatic perfusion, and vascular anatomy of dogs with congenital extrahepatic portosystemic shunts, before and after attenuation with an ameroid constrictor. Study Design Prospective study. Animals Dogs (n = 22) with congenital extrahepatic portosystemic shunts. Methods CT angiography and perfusion scans were performed before and after attenuation of a portosystemic shunt with an ameroid constrictor. Changes in hepatic volume, hepatic perfusion, and vascular anatomy were measured. Portal scintigraphy was performed in 8 dogs preoperatively and 22 dogs postoperatively. Results Dogs with smaller preoperative liver volumes had greater increases in liver volume postoperatively compared with those with larger preoperative liver volumes. Hepatic arterial fraction was increased in dogs preoperatively and returned to normal range after shunt attenuation, and was correlated with increase in liver size and decreased shunt fraction. Three dogs with no visible portal vasculature preoperatively developed portal branches postoperatively. Conclusions Dogs with smaller preoperative liver volumes had the largest postoperative increase in liver volume. Hepatic arterial perfusion and portal scintigraphy correlate with liver volume and are indicators of successful shunt attenuation. Dogs without visible vasculature on CT angiography had visible portal vasculature postoperatively.
    Type of Medium: Online Resource
    ISSN: 0161-3499 , 1532-950X
    URL: Issue
    URL: Article
    DOI: 10.1111/vsu.v43.8
    DOI: 10.1111/j.1532-950X.2014.12193.x
    Language: English
    Publisher: Wiley
    Publication Date: 2014
    detail.hit.zdb_id: 1491071-8
    SSG: 22
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  • 8
    Online Resource
    Online Resource
    Short‐Term Outcome of Multiple Port Laparoscopic Splenectomy in 10 Dogs
    Wiley ; 2015
    In:  Veterinary Surgery Vol. 44, No. S1 ( 2015-07), p. 71-75
    Details
    In: Veterinary Surgery, Wiley, Vol. 44, No. S1 ( 2015-07), p. 71-75
    Abstract: To describe surgical techniques for multiple port laparoscopic splenectomy (MLS) in dogs and report short‐term outcome. Study design Retrospective case series. Animals Dogs (n = 10) with naturally occurring splenic disease. Methods Medical records (March 2012–March 2013) of dogs that had MLS were reviewed. Data retrieved included signalment, weight, clinical signs, physical examination findings, preoperative laboratory and ultrasonographic findings, port number, size, and location, patient positioning, additional procedures performed, surgical duration, histopathologic diagnosis, duration of hospitalization, and perioperative complications. Results Ten dogs (median weight, 28.7 kg; range, 20.2–46.0 kg) had MLS using a 3 or 4 port technique and a vessel‐sealing device for tissue dissection along the splenic hilus. Dog positioning varied because of additional laparoscopic or laparoscopic‐assisted procedures including adrenalectomy (n = 2), ovariectomy (1), gastropexy (1), and intestinal resection and anastomosis (1). Conversion to an open approach was necessary in 1 dog because of inadequate visibility caused by omental adhesions. One dog had hemorrhage from an omental vessel, but open conversion was not required. Conclusions MLS was associated with little perioperative morbidity and few complications in this cohort of dogs and may be a reasonable option for surgical management of dogs requiring elective splenectomy.
    Type of Medium: Online Resource
    ISSN: 0161-3499 , 1532-950X
    URL: Issue
    URL: Article
    DOI: 10.1111/vsu.v44.S1
    DOI: 10.1111/j.1532-950X.2014.12312.x
    Language: English
    Publisher: Wiley
    Publication Date: 2015
    detail.hit.zdb_id: 1491071-8
    SSG: 22
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  • 9
    Online Resource
    Online Resource
    Validation of the OAKS prognostic model for acute kidney injury after gastrointestinal surgery
    Oxford University Press (OUP) ; 2022
    In:  BJS Open Vol. 6, No. 1 ( 2022-01-06)
    Details
    In: BJS Open, Oxford University Press (OUP), Vol. 6, No. 1 ( 2022-01-06)
    Abstract: Postoperative acute kidney injury (AKI) is a common complication of major gastrointestinal surgery with an impact on short- and long-term survival. No validated system for risk stratification exists for this patient group. This study aimed to validate externally a prognostic model for AKI after major gastrointestinal surgery in two multicentre cohort studies. Methods The Outcomes After Kidney injury in Surgery (OAKS) prognostic model was developed to predict risk of AKI in the 7 days after surgery using six routine datapoints (age, sex, ASA grade, preoperative estimated glomerular filtration rate, planned open surgery and preoperative use of either an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker). Validation was performed within two independent cohorts: a prospective multicentre, international study (‘IMAGINE’) of patients undergoing elective colorectal surgery (2018); and a retrospective regional cohort study (‘Tayside’) in major abdominal surgery (2011–2015). Multivariable logistic regression was used to predict risk of AKI, with multiple imputation used to account for data missing at random. Prognostic accuracy was assessed for patients at high risk (greater than 20 per cent) of postoperative AKI. Results In the validation cohorts, 12.9 per cent of patients (661 of 5106) in IMAGINE and 14.7 per cent (106 of 719 patients) in Tayside developed 7-day postoperative AKI. Using the OAKS model, 558 patients (9.6 per cent) were classified as high risk. Less than 10 per cent of patients classified as low-risk developed AKI in either cohort (negative predictive value greater than 0.9). Upon external validation, the OAKS model retained an area under the receiver operating characteristic (AUC) curve of range 0.655–0.681 (Tayside 95 per cent c.i. 0.596 to 0.714; IMAGINE 95 per cent c.i. 0.659 to 0.703), sensitivity values range 0.323–0.352 (IMAGINE 95 per cent c.i. 0.281 to 0.368; Tayside 95 per cent c.i. 0.253 to 0.461), and specificity range 0.881–0.890 (Tayside 95 per cent c.i. 0.853 to 0.905; IMAGINE 95 per cent c.i. 0.881 to 0.899). Conclusion The OAKS prognostic model can identify patients who are not at high risk of postoperative AKI after gastrointestinal surgery with high specificity. Presented to Association of Surgeons in Training (ASiT) International Conference 2018 (Edinburgh, UK), European Society of Coloproctology (ESCP) International Conference 2018 (Nice, France), SARS (Society of Academic and Research Surgery) 2020 (Virtual, UK).
    Type of Medium: Online Resource
    ISSN: 2474-9842
    URL: Article
    DOI: 10.1093/bjsopen/zrab150
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2022
    detail.hit.zdb_id: 2902033-5
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  • 10
    Online Resource
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    Impact of postoperative acute kidney injury in patients undergoing major gastrointestinal surgery on 1-year survival and renal outcomes: a national multicentre cohort study
    Oxford University Press (OUP) ; 2021
    In:  BJS Open Vol. 5, No. 6 ( 2021-11-09)
    Details
    In: BJS Open, Oxford University Press (OUP), Vol. 5, No. 6 ( 2021-11-09)
    Abstract: The intermediate-term impact of acute kidney injury (AKI) in patients after major gastrointestinal and liver surgery has not been well characterized. This study aimed to evaluate the 1-year mortality rate and renal outcomes associated with postoperative AKI in a national prospective cohort. Methods This prospective multicentre, observational cohort with 1-year postoperative follow-up included adults undergoing major gastrointestinal and liver surgery across the UK and Ireland between 23 September and 18 November 2015. AKI was defined according to Kidney Disease Improving Global Outcomes (KDIGO) criteria. The primary outcome was death at 1-year after surgery, and the secondary outcome was Major Adverse Kidney Events (MAKE-365). Cox proportionate and multilevel logistic regression were used to account for case mix. Results Of 5745 patients across 173 centres, 1-year follow-up data was completed for 3504 patients (62.2 per cent, 126 centres), with attrition largely explained by centre non-participation (63.1 per cent). Some 13.6 per cent (475 of 3504) patients developed AKI by 7 days after surgery (stage 1: 9.2 per cent; stage 2/3: 4.3 per cent). At 1 year, 10.8 per cent (378 patients) experienced a MAKE-365 endpoint (303 patients had died, 61 had renal replacement therapy and 78 had renal dysfunction). Patients who experienced AKI by 7 days after surgery had a higher hazard of death at 1 year for KDIGO stage 1 (hazard ratio 1.50 (95 per cent c.i. 1.08 to 2.08), P = 0.016) and KDIGO stage 2/3 (hazard ratio 2.96 (95 per cent c.i. 2.02 to 4.33), P & lt; 0.001). Both KDIGO stage 1 (odds ratio 2.09 (95 per cent c.i. 1.50 to 2.92), P & lt; 0.001) and stage 2/3 (odds ratio 9.26 (95 per cent c.i. 6.31 to 13.59), P & lt; 0.001) AKI were independently associated with MAKE-365. Conclusion AKI events within 7 days after gastrointestinal or liver surgery are associated with significantly worse survival and renal outcomes at 1 year.
    Type of Medium: Online Resource
    ISSN: 2474-9842
    URL: Article
    DOI: 10.1093/bjsopen/zrab134
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2021
    detail.hit.zdb_id: 2902033-5
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