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  • 1
    Online Resource
    Online Resource
    Screening for post‐traumatic stress disorders in 1017 cancer patients and correlation with anxiety, depression, and distress
    Wiley ; 2019
    In:  Psycho-Oncology Vol. 28, No. 12 ( 2019-12), p. 2382-2388
    Details
    In: Psycho-Oncology, Wiley, Vol. 28, No. 12 ( 2019-12), p. 2382-2388
    Abstract: Post‐traumatic stress disorder (PTSD) is a severe psychiatric disorder, which might develop after a traumatic event, like cancer diagnosis, and threatens the patient's psychological and/or physiological integrity. Anxiety, depression, and mental distress are known to be common in cancer patients; however, the frequency of PTSD was not investigated thoroughly in this patient group so far. Here, we aim to screen cancer patients for PTSD symptoms and determine a possible correlation with anxiety, depression, and distress. Methods The study was performed at the Divisions of Hematology and Oncology of the Medical University of Vienna from 2010 to 2018. Following written consent, patients were asked to fill out the validated self‐assessment questionnaire for PTSS‐10 and HADS. The study was approved by the institutional ethics committee of the Medical University of Vienna (EC Nr: 2255/2016). Results A total of 1017 adult cancer patients (513 male, 504 female) were included in a cross‐sectional single‐center study. Mean age was 57.6 years (SD 14.4 years); 31.7%, 14.6%, 13.2%, and 27.4% of patients outscored the predefined thresholds for self‐assessed cases of PTSD, anxiety, depression, and distress, respectively. Compared with men, women showed a higher prevalence of symptoms for PTSD (38.9% vs 24.5%; P   〈  .001) and anxiety (20.4% vs 8.6%; P   〈  .001). The scores of HADS‐A, HADS‐D, and the combined HADS score (distress) were significantly correlated with PTSS‐10 scores ( P   〈  .01). No differences in age were observed among the different score groups. Conclusion The study shows a significant prevalence as well as a correlation of PTSD symptoms with anxiety, depression, and distress among cancer patients. Findings underscore the necessity of a serious screening for psychiatric disorders, especially in female patients. In order to enable multidisciplinary care for cancer patients and to reduce the burden for psychiatric disorders, interdisciplinary screening and treatment concepts, which take into account gender aspects, are urged.
    Type of Medium: Online Resource
    ISSN: 1057-9249 , 1099-1611
    URL: Issue
    URL: Article
    DOI: 10.1002/pon.v28.12
    DOI: 10.1002/pon.5239
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 1118536-3
    detail.hit.zdb_id: 1495115-0
    SSG: 5,2
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  • 2
    Online Resource
    Online Resource
    The impact of COVID-19 and socioeconomic status on psychological distress in cancer patients
    Elsevier BV ; 2023
    In:  International Journal of Clinical and Health Psychology Vol. 23, No. 4 ( 2023-10), p. 100404-
    Details
    In: International Journal of Clinical and Health Psychology, Elsevier BV, Vol. 23, No. 4 ( 2023-10), p. 100404-
    Type of Medium: Online Resource
    ISSN: 1697-2600
    URL: Article
    DOI: 10.1016/j.ijchp.2023.100404
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
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  • 3
    Online Resource
    Online Resource
    Consistent signals of a warming climate in occupancy changes of three insect taxa over 40 years in central Europe
    Wiley ; 2022
    In:  Global Change Biology Vol. 28, No. 13 ( 2022-07), p. 3998-4012
    Details
    In: Global Change Biology, Wiley, Vol. 28, No. 13 ( 2022-07), p. 3998-4012
    Abstract: Jüngste Klima‐ und Landnutzungsänderungen haben erhebliche Auswirkungen auf die biologische Vielfalt, wie z. B. Populationsrückgänge, Verlagerung von Verbreitungsgebieten sowie Veränderungen in der Zusammensetzung von Lebensgemeinschaften. Nur wenige Studien bisher haben diese Auswirkungen auf unterschiedliche Taxa verglichen, insbesondere in Ermangelung an standardisierten Zeitreihendaten über lange Zeiträume. Vorhandene Datensätze sind räumlich und zeitlich oft wenig umfangreich, was Rückschlüsse, die aus solchen Studien gezogen werden können, einschränkt. Hier vergleichen wir klimatisch und landnutzungsbedingte Vorkommensänderungen bei Schmetterlingen, Heuschrecken und Libellen anhand eines umfangreichen Datensatzes mit sehr heterogenen Beobachtungsdaten, die in der mitteleuropäischen Region Bayern (Deutschland) über einen Zeitraum von 40 Jahren gesammelt wurden. Anhand von Occupancy‐Modellen stellten wir fest, dass die Occupancy (Anteil der von einer Art besetzten Standorte pro Jahr) bei 37% der Arten abnahm, bei 30% zunahm und bei 33% keinen signifikanten Trend zeigte. Schmetterlinge und Heuschrecken wiesen mit jeweils 41% der Arten die stärksten Rückgänge auf. Dagegen nahmen 52% der Libellenarten zu. Temperaturpräferenz und Habitatspezifität scheinen die wichtigsten Faktoren für die Trendentwicklungen der Arten zu sein. Wir zeigen, dass kälteangepasste Arten in allen Taxa zurückgingen, während wärmeangepasste Arten zunahmen. Darüber hinaus nahmen bei Schmetterlingen Lebensraumspezialisten ab, während Generalisten zunahmen oder stabil blieben. Unsere Ergebnisse deuten auf starke und konsistente Auswirkungen der Klimaerwärmung auf alle untersuchten Insektentaxa hin. Der Rückgang von Schmetterlingsspezialisten (im Gegensatz zu den semiaquatischen Libellen, bei denen sowohl Generalisten als auch Spezialisten zunahmen) könnte auf eine Bedrohung in terrestrischen Lebensräumen hindeuten, da das Vorkommen insbesondere von Schmetterlingsspezialisten hauptsächlich von der Lebensraumqualität und ‐fläche abhängt. Beides hat sich in den letzten Jahrzehnten in aquatischen Lebensräumen verbessert, nicht jedoch in terrestrischen Lebensräumen. Unsere Studie veranschaulicht, warum diese Taxa in der Vergangenheit unterschiedliche Trends aufwiesen, und wie wir die nachteiligen Auswirkungen anthropogener Aktivitäten auf ihre Vielfalt in Zukunft abmildern können.
    Type of Medium: Online Resource
    ISSN: 1354-1013 , 1365-2486
    URL: Issue
    URL: Article
    DOI: 10.1111/gcb.v28.13
    DOI: 10.1111/gcb.16200
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 1281439-8
    detail.hit.zdb_id: 2020313-5
    SSG: 12
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  • 4
    Online Resource
    Online Resource
    Treatment strategies in patients with gynecological sarcoma: Results of the prospective intergroup real-world registry for gynecological sarcoma in Germany (REGSA-NOGGO RU1)
    BMJ ; 2023
    In:  International Journal of Gynecologic Cancer Vol. 33, No. 2 ( 2023-02), p. 223-230
    Details
    In: International Journal of Gynecologic Cancer, BMJ, Vol. 33, No. 2 ( 2023-02), p. 223-230
    Abstract: Gynecological sarcomas account for 3% of all gynecological malignancies and are associated with a poor prognosis. Due to the rarity and heterogeneity of gynecological sarcomas there is still no consensus on optimal therapeutic strategies. This study’s objective was to describe the treatment strategies used in patients with gynecological sarcomas in the primary course of disease. Methods The German prospective registry for gynecological sarcoma (REGSA) is the largest registry for gynecological sarcomas in Germany, Austria and Switzerland. Primary inclusion criteria for REGSA are histological diagnosis of sarcoma of the female genital tract, sarcoma of the breast or uterine smooth muscle tumors of uncertain malignant potential (STUMP). We evaluated data of the REGSA registry on therapeutic strategies used for primary treatment from August 2015 to February 2021. Results A total of 723 patients from 120 centers were included. Data on therapeutic strategies for primary treatment were available in 605 cases. Overall, 580 (95.9%) patients underwent primary surgery, 472 (81.4%) of whom underwent only hysterectomy. Morcellation was reported in 11.4% (n=54) of all hysterectomies. A total of 42.8% (n=202) had no further surgical interventions, whereas an additional salpingo-ophorectomy was performed in 54% (n=255) of patients. An additional lymphadenectomy was performed in 12.7% (n=60), an omentectomy in 9.5% (n=45) and intestinal resection in 6.1% (n=29) of all patients. Among 448 patients with available information, 21.4% (n=96) received chemo- or targeted therapies, more commonly as single-agent treatment than as drug combinations. Information about anti-hormonal treatment was available for 423 patients, among which 42 (9.9%) received anti-hormonal treatment, 23 (54.8%) of whom with low-grade endometrial stroma sarcomas. For radiotherapy, data of 437 patients were available, among which 29 (6.6%) patients underwent radiotherapy. Conclusion Our study showed that treatment of patients with gynecologic sarcomas is heterogeneous. Further trials are needed along with more information on treatment modalities, therapy response and patient-reported outcomes to implement new treatment strategies.
    Type of Medium: Online Resource
    ISSN: 1048-891X , 1525-1438
    URL: Article
    DOI: 10.1136/ijgc-2022-003800
    Language: English
    Publisher: BMJ
    Publication Date: 2023
    detail.hit.zdb_id: 2009072-9
    detail.hit.zdb_id: 1070385-8
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  • 5
    Online Resource
    Online Resource
    Bioenergy cropland expansion may offset positive effects of climate change mitigation for global vertebrate diversity
    Proceedings of the National Academy of Sciences ; 2018
    In:  Proceedings of the National Academy of Sciences Vol. 115, No. 52 ( 2018-12-26), p. 13294-13299
    Details
    In: Proceedings of the National Academy of Sciences, Proceedings of the National Academy of Sciences, Vol. 115, No. 52 ( 2018-12-26), p. 13294-13299
    Abstract: Climate and land-use change interactively affect biodiversity. Large-scale expansions of bioenergy have been suggested as an important component for climate change mitigation. Here we use harmonized climate and land-use projections to investigate their potential combined impacts on global vertebrate diversity under a low- and a high-level emission scenario. We combine climate-based species distribution models for the world’s amphibians, birds, and mammals with land-use change simulations and identify areas threatened by both climate and land-use change in the future. The combined projected effects of climate and land-use change on vertebrate diversity are similar under the two scenarios, with land-use change effects being stronger under the low- and climate change effects under the high-emission scenario. Under the low-emission scenario, increases in bioenergy cropland may cause severe impacts in biodiversity that are not compensated by lower climate change impacts. Under this low-emission scenario, larger proportions of species distributions and a higher number of small-range species may become impacted by the combination of land-use and climate change than under the high-emission scenario, largely a result of bioenergy cropland expansion. Our findings highlight the need to carefully consider both climate and land-use change when projecting biodiversity impacts. We show that biodiversity is likely to suffer severely if bioenergy cropland expansion remains a major component of climate change mitigation strategies. Our study calls for an immediate and significant reduction in energy consumption for the benefit of both biodiversity and to achieve the goals of the Paris Agreement.
    Type of Medium: Online Resource
    ISSN: 0027-8424 , 1091-6490
    URL: Article
    DOI: 10.1073/pnas.1807745115
    RVK:
    TA 1000
    RVK:
    WA 15000
    Language: English
    Publisher: Proceedings of the National Academy of Sciences
    Publication Date: 2018
    detail.hit.zdb_id: 209104-5
    detail.hit.zdb_id: 1461794-8
    SSG: 11
    SSG: 12
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  • 6
    Online Resource
    Online Resource
    Effectiveness of Usual-Care Cognitive Behavioral Therapy for Adolescents with School Absenteeism
    Hogrefe Publishing Group ; 2022
    In:  Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie Vol. 50, No. 6 ( 2022-11-01), p. 436-446
    Details
    In: Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie, Hogrefe Publishing Group, Vol. 50, No. 6 ( 2022-11-01), p. 436-446
    Abstract: Abstract. Objective: Highly-controlled, randomized controlled trials have provided considerable evidence for the efficacy of outpatient cognitive-behavioral therapy (CBT) for patients with school absenteeism and anxiety disorders. However, the effectiveness of outpatient CBT under routine-care conditions for youth with school absenteeism remains unproven. Methods: This observational study used file records to analyze the changes under routine CBT in a sample of n = 49 clinically referred adolescents aged 11 to 18 years with school absenteeism and mental disorders who were being treated in a university outpatient clinic. At the start and end of treatment, we assessed the severity of school absenteeism as well as mental health problems as rated by parents and by the adolescents themselves. Results: The analysis yielded a statistically highly significant decline in school absenteeism (large effect, Cohen’s r = 0.80) and in mental health problems (small-to-large effect, Cohen’s d = 0.33 to d = 0.82). However, a substantial proportion of the sample remained in the clinical range at the end of treatment. Conclusions: These findings suggest that CBT is effective for adolescents with school absenteeism when administered under routine-care conditions, though the results must be interpreted with caution because of the lack of a control condition.
    Type of Medium: Online Resource
    ISSN: 1422-4917 , 1664-2880
    URL: Article
    DOI: 10.1024/1422-4917/a000883
    Language: German
    Publisher: Hogrefe Publishing Group
    Publication Date: 2022
    detail.hit.zdb_id: 1312929-6
    detail.hit.zdb_id: 2083294-1
    SSG: 2,1
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  • 7
    Online Resource
    Online Resource
    Kidney Function Worsening Is Linked to Parenteral-Nutrition-Dependent Survival in Palliative Care Patients
    MDPI AG ; 2022
    In:  Nutrients Vol. 14, No. 4 ( 2022-02-11), p. 769-
    Details
    In: Nutrients, MDPI AG, Vol. 14, No. 4 ( 2022-02-11), p. 769-
    Abstract: Background. Parenteral nutrition (PN) is frequently administered in palliative care patients suffering from cachexia. The evidence regarding the use of PN in terminally ill patients is scarce. Routine laboratory parameters might help to decide whether to start or forgo PN, which could decrease overtreatment at the end of life. Kidney failure was frequently associated with survival. However, a relation between kidney function parameters and parenteral nutrition has not been observed thus far. The aim of this retrospective cohort study was to analyze kidney function parameters in palliative care patients under PN, as well as the relation between these parameters and overall survival. Methods. Patients who were admitted to the Department of Palliative Medicine at the Medical University of Vienna were screened for PN treatment. Whether kidney function parameters at baseline or their dynamics over the course of two weeks were associated with survival was assessed with descriptive and interferential statistics. Results. In total, 113 of 443 palliative care patients were administered parenteral nutrition for the first time. The overall survival (OS) for all patients with increased kidney function parameters at baseline was lower (creatinine: hazard ratio (HR) = 1.808, p 〈 0.001; urea: HR = 1.033, p 〈 0.001; uric acid HR = 1.055, p = 0.015). No significant increase in creatinine blood levels was observed in the first 2 weeks after the initiation of PN when compared to the non-PN group (p = 0.86). However, if creatinine blood levels increased within the PN group, lower overall survival was found (HR = 2.046, p = 0.007). Conclusion. Increased kidney function parameters, such as creatinine, urea and uric acid, might be used as negative prognostic markers in palliative care patients under PN. Moreover, an increase in creatinine during the administration of parenteral nutrition in the first 2 weeks is linked to worse outcomes. These findings may help future studies to establish objective markers for clinicians to determine whether to start or end PN in palliative cancer patients and decrease potential overtreatment at the end of life.
    Type of Medium: Online Resource
    ISSN: 2072-6643
    URL: Article
    DOI: 10.3390/nu14040769
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2518386-2
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  • 8
    Online Resource
    Online Resource
    Vitamin “G”arden: a qualitative study exploring perception/s of horticultural therapy on a palliative care ward
    Springer Science and Business Media LLC ; 2018
    In:  Supportive Care in Cancer Vol. 26, No. 6 ( 2018-6), p. 1799-1805
    Details
    In: Supportive Care in Cancer, Springer Science and Business Media LLC, Vol. 26, No. 6 ( 2018-6), p. 1799-1805
    Type of Medium: Online Resource
    ISSN: 0941-4355 , 1433-7339
    URL: Article
    DOI: 10.1007/s00520-017-3978-z
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2018
    detail.hit.zdb_id: 1134446-5
    detail.hit.zdb_id: 1463166-0
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  • 9
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    Online Resource
    Retrospective qualitative pilot study incorporating patients’ personal life aspects on admission to palliative care : What should we know about patients to give them the best possible care?
    Springer Science and Business Media LLC ; 2019
    In:  Wiener klinische Wochenschrift Vol. 131, No. 21-22 ( 2019-11), p. 576-581
    Details
    In: Wiener klinische Wochenschrift, Springer Science and Business Media LLC, Vol. 131, No. 21-22 ( 2019-11), p. 576-581
    Abstract: This pilot study examined which of a patient’s personal aspects should be taken into account in a hospital setting on admission to the palliative care unit (PCU) by asking patients the question “what should I know about you as a person to help me take the best care of you that I can?” Methods This retrospective study used qualitative methodology to thematically analyze answers from 14 patients admitted to the PCU of the Medical University of Vienna during July and August 2018. The question “what should I know about you as a person to help me take the best care of you that I can?” was asked on the day of admission, notes were taken during the interview and the patient’s answers were written out immediately afterwards. Data were analyzed using NVivo 12. Results Results revealed four topics: characterization of one’s personality, important activities, social bonding, and present and future concerns regarding the patient’s illness. Data showed that this question enabled patients to describe themselves and what was important to them. This might result in an improved sense of self-esteem in patients and represents an opportunity for professionals to treat patients in a more individualized manner; however, patient reactions also revealed a reluctance to address certain personal issues within a medical context. Conclusion The study results provide insights into the benefits of paying more attention to personal life aspects of severely ill patients on admission to a PCU. Addressing individual aspects of patients’ lives might improve the healthcare professional-patient relationship.
    Type of Medium: Online Resource
    ISSN: 0043-5325 , 1613-7671
    URL: Article
    DOI: 10.1007/s00508-019-01552-5
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2019
    detail.hit.zdb_id: 2244243-1
    detail.hit.zdb_id: 200462-8
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  • 10
    Online Resource
    Online Resource
    Trends and Patterns in the Public Awareness of Palliative Care, Euthanasia, and End-of-Life Decisions in 3 Central European Countries Using Big Data Analysis From Google: Retrospective Analysis
    JMIR Publications Inc. ; 2021
    In:  Journal of Medical Internet Research Vol. 23, No. 9 ( 2021-9-20), p. e28635-
    Details
    In: Journal of Medical Internet Research, JMIR Publications Inc., Vol. 23, No. 9 ( 2021-9-20), p. e28635-
    Abstract: End-of-life decisions, specifically the provision of euthanasia and assisted suicide services, challenge traditional medical and ethical principles. Austria and Germany have decided to liberalize their laws restricting assisted suicide, thus reigniting the debate about a meaningful framework in which the practice should be embedded. Evidence of the relevance of assisted suicide and euthanasia for the general population in Germany and Austria is limited. Objective The aim of this study is to examine whether the public awareness documented by search activities in the most frequently used search engine, Google, on the topics of palliative care, euthanasia, and advance health care directives changed with the implementation of palliative care services and new governmental regulations concerning end-of-life decisions. Methods We searched for policies, laws, and regulations promulgated or amended in Austria, Germany, and Switzerland between 2004 and 2020 and extracted data on the search volume for each search term topic from Google Trends as a surrogate of public awareness and interest. Annual averages were analyzed using the Joinpoint Regression Program. Results Important policy changes yielded significant changes in search trends for the investigated topics. The enactment of laws regulating advance health care directives coincided with a significant drop in the volume of searches for the topic of euthanasia in all 3 countries (Austria: −24.48%, P=.02; Germany: −14.95%, P 〈 .001; Switzerland: −11.75%, P=.049). Interest in palliative care increased with the availability of care services and the implementation of laws and policies to promote palliative care (Austria: 22.69%, P=.01; Germany: 14.39, P 〈 .001; Switzerland: 17.59%, P 〈 .001). The search trends for advance health care directives showed mixed results. While interest remained steady in Austria within the study period, it increased by 3.66% (P 〈 .001) in Switzerland and decreased by 2.85% (P 〈 .001) in Germany. Conclusions Our results demonstrate that legal measures securing patients’ autonomy at the end of life may lower the search activities for topics related to euthanasia and assisted suicide. Palliative care may be a meaningful way to raise awareness of the different options for end-of-life care and to guide patients in their decision-making process regarding the same.
    Type of Medium: Online Resource
    ISSN: 1438-8871
    URL: Article
    DOI: 10.2196/28635
    Language: English
    Publisher: JMIR Publications Inc.
    Publication Date: 2021
    detail.hit.zdb_id: 2028830-X
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