In:
International Journal of Cancer, Wiley, Vol. 144, No. 6 ( 2019-03-15), p. 1275-1283
Abstract:
What's new? How does lymphocyte telomere length affect pancreatic cancer risk? These authors analyzed 10 SNPs associated with telomere length and their relationship with pancreatic cancer risk, using data from the Pancreatic Disease Research (PANDoRA) consortium. Each patient received a “teloscore” based on the combined SNP data, and it turned out that a low teloscore ‐ predicting a short telomere ‐ was associated with increased pancreatic cancer risk. The researchers also identified for the first time a significant genome‐wide association between a SNP, TERT ‐rs2736100, and increased pancreatic cancer risk. They also discovered a completely novel association between a SNP, NAF1 ‐rs7675998, and decreased risk.
Type of Medium:
Online Resource
ISSN:
0020-7136
,
1097-0215
Language:
English
Publisher:
Wiley
Publication Date:
2019
detail.hit.zdb_id:
218257-9
detail.hit.zdb_id:
1474822-8
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