In:
Reviews on Clinical Pharmacology and Drug Therapy, ECO-Vector LLC, Vol. 20, No. 2 ( 2022-10-03), p. 149-156
Abstract:
Depression is a widespread, severely debilitating mental disorder characterized by low mood, anhedonia, fatigue, decreased attention, suicidality and psychomotor retardation, accompanied by neuroendocrine and molecular disorders. Zebrafish have neuroendocrine and neurotransmitter systems similar to humans, as well as high genetic homology, and are rapidly becoming popular model organisms for modeling depressive-like conditions. Here, we discuss modern behavioral, pharmacological and genetic models of depression in zebrafish, their methodological applications and translational implications.
Type of Medium:
Online Resource
ISSN:
2542-1875
,
1683-4100
DOI:
10.17816/RCF202149-156
Language:
Unknown
Publisher:
ECO-Vector LLC
Publication Date:
2022
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