In:
Canadian Journal of Gastroenterology and Hepatology, Hindawi Limited, Vol. 2018 ( 2018-08-01), p. 1-7
Abstract:
Background . Portal hypertension is a serious complication of liver cirrhosis. Objective . To identify relevant endoscopic findings in patients with advanced cirrhosis and consecutive portal hypertension. Methods . This was a retrospective study of liver transplant candidates who underwent upper gastrointestinal endoscopy between April 2011 and November 2015. Results . A total of 1,045 upper endoscopies were analyzed. Portal hypertensive gastric and duodenal polyps were frequently observed and were associated with thrombocytopenia (p = 0.040; OR: 2.4, 95% CI 1.04–5.50), Child-Pugh score 〉 6 (p = 0.033; OR: 2.3, 95% CI 1.07–4.92), Model for End Stage Liver Disease score 〉 16 (p = 0.030; OR: 4.1, 95% CI 1.14–15.00), and previous rubber band ligation (p 〈 0.001; OR = 5.2, 95% CI 2.5–10.7). These polyps often recurred after polypectomy; however, no malignant transformation occurred during the observational time until October 2017. The most common endoscopic finding was esophageal varices, observed in more than 90% of patients. Conclusion . Portal hypertensive polyposis is common in patients with advanced cirrhosis. Our data suggest that these polyps have benign characteristics.
Type of Medium:
Online Resource
ISSN:
2291-2789
,
2291-2797
DOI:
10.1155/2018/2182784
Language:
English
Publisher:
Hindawi Limited
Publication Date:
2018
detail.hit.zdb_id:
2762184-4
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