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  • 1
    Online Resource
    Online Resource
    Effect of ATP-binding Cassette Transporter A1 (ABCA1) Gene Polymorphisms on Plasma Lipid Variables and Common Demographic Parameters in Greek Nurses
    Bentham Science Publishers Ltd. ; 2016
    In:  The Open Cardiovascular Medicine Journal Vol. 10, No. 1 ( 2016-11-21), p. 233-239
    Details
    In: The Open Cardiovascular Medicine Journal, Bentham Science Publishers Ltd., Vol. 10, No. 1 ( 2016-11-21), p. 233-239
    Abstract: The present study is on line with our previous studies evaluating the influence of ATP-binding cassette transporter A1 ( ABCA1 ) gene polymorphisms on the lipid variables of Greek student-nurses. The current study was undertaken to (1) estimate the influence of variant(s) such as rs2066715 (V825I), R219K, R1587K, I883M of ABCA1 gene on lipid variables and (2) evaluate the effect of all four ABCA1 polymorphisms on common demographic parameters. Methods: The study population involved 432 unrelated nurses (86 men) who were genotyped for ABCA1 polymorphisms and correlated according to lipid variables [total cholesterol (TC), triglycerides (TGs), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and apolipoprotein (apo) A] and demographic parameters (age, gender, BMI, waist circumference). Results: According to lipid variables concentration there was no difference between genotypes and alleles of V825I, R219K and I883M polymorphisms. The LDL-C concentration was 13% lower in RR compared with RK genotype (100.7 vs . 113.9 mg/dl, p=0.013) of R1587K gene polymorphism. In regression analysis the effects of age, gender and only R1587K gene polymorphism on LDL-C concentrations were proved significant. Additionally, LDL-C was increased (by 1.29 mg/dl on average) by every year of increase of age. Moreover, females had lower LDL-C concentrations as compared with males. Conclusion: Findings suggested that only R1587K polymorphism of ABCA1 gene was associated with lipid variables, age, and gender of Greek nurses. These findings may be helpful in assessing the risk factors for premature coronary heart disease and distinct individuals with lower/higher atherosclerotic burden.
    Type of Medium: Online Resource
    ISSN: 1874-1924
    URL: Article
    DOI: 10.2174/1874192401610010233
    Language: English
    Publisher: Bentham Science Publishers Ltd.
    Publication Date: 2016
    detail.hit.zdb_id: 2430362-8
    detail.hit.zdb_id: 2396047-4
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  • 2
    Online Resource
    Online Resource
    ATP-binding cassette transporter A1 gene polymorphisms and serum lipid levels in young Greek nurses
    Springer Science and Business Media LLC ; 2011
    In:  Lipids in Health and Disease Vol. 10, No. 1 ( 2011), p. 56-
    Details
    In: Lipids in Health and Disease, Springer Science and Business Media LLC, Vol. 10, No. 1 ( 2011), p. 56-
    Type of Medium: Online Resource
    ISSN: 1476-511X
    URL: Article
    DOI: 10.1186/1476-511X-10-56
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2011
    detail.hit.zdb_id: 2091381-3
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  • 3
    Online Resource
    Online Resource
    Association of gender, ABCA1 gene polymorphisms and lipid profile in Greek young nurses
    Springer Science and Business Media LLC ; 2012
    In:  Lipids in Health and Disease Vol. 11, No. 1 ( 2012), p. 62-
    Details
    In: Lipids in Health and Disease, Springer Science and Business Media LLC, Vol. 11, No. 1 ( 2012), p. 62-
    Type of Medium: Online Resource
    ISSN: 1476-511X
    URL: Article
    DOI: 10.1186/1476-511X-11-62
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2012
    detail.hit.zdb_id: 2091381-3
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  • 4
    Online Resource
    Online Resource
    Quality of life in patients after brain meningioma resection
    National Documentation Centre (EKT) ; 2018
    In:  Health & Research Journal Vol. 1, No. 1 ( 2018-12-06), p. 3-
    Details
    In: Health & Research Journal, National Documentation Centre (EKT), Vol. 1, No. 1 ( 2018-12-06), p. 3-
    Abstract: Introduction: Lately it has been noticed an increasing interest about the quality of life that is related to theperformance - effectiveness indicators and also to the objective and subjective state of patients’ health.Psychosocial problems are detected by quality questionnaires which may bother the healing process and help tothe disability rate and diagnosis of the disability. Meningioma is concerned as a benign tumor which is growingslowly .Usually the relapse rates are low in total surgical excision.Aim: The aim of the present review was to explore quality of life of patients surgically treated for brainmeningioma, in order to improve disease outcomes.Methodology: The methodology that was used included the review of the Greek and international literature of thelast fifteen years in the databases (Pubmed, Scopus, Google Scholar,medline). The keywords that were used tosearch for the study were: “meningioma", “quality of life”, “SF36”, “patients” Health related quality of life”.Results: Literature review has shown that the quality of life of patients with brain meningioma depends on variousfactors among others the most important are location and accessibility of the tumor. The best of the treatment isnot limited only to the surgical part required but it is a combination of radiation treatment for better results. Whenmeningioma is totally surgical resected displays minimal relaplse rates in contrast to the partial resection where itreoccurs in percentage 48% during the next five years. Meningiomas that cannot be petroclival surgically such asindicate high morbidity, mortality and poor physical function. Intraventricular meningiomas remain malfuctions ofvision, etc. Furthermore, a significant sign is the edema which may be associated with the aggressiveness of thetumor. Finally a possibility of reoccurrence factor is the number of mitoses in the pathological analysis.Conclusions: The quality of life of patients that had been operated with brain meningioma vary at relatively lowlevels and is directly related to the tumor’s localization and the choice of treatment.
    Type of Medium: Online Resource
    ISSN: 2459-3192 , 2459-3192
    URL: Article
    DOI: 10.12681/healthresj.19274
    Language: Unknown
    Publisher: National Documentation Centre (EKT)
    Publication Date: 2018
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  • 5
    Online Resource
    Online Resource
    The role of using a special support surface in heel pressure ulcers appearance in intensive care unit patients
    National Documentation Centre (EKT) ; 2018
    In:  Health & Research Journal Vol. 4, No. 2 ( 2018-12-02), p. 99-
    Details
    In: Health & Research Journal, National Documentation Centre (EKT), Vol. 4, No. 2 ( 2018-12-02), p. 99-
    Abstract: Introduction: Intensive Care Unit (ICU) patients suffer complications such as the development of pressure ulcers. Aim: The purpose of this study was to investigate the relationship between the use of special designed heel protector and the frequency and severity of heel pressure ulcers occurrence in ICU patients. Material and Method: The studied sample consisted of 40 patients hospitalized in ICU of a general hospital in Attica. Hospital Acquired Skin Injury (HASI) and Cubin Jackson (Score Cubin-Jackson) were used and data analysis was performed by the statistical package SPSS 19. Results: 62,5% of the studied sample were men, with mean age 59±17.7 years and length of hospital stay 21.4±18 days. The preventive intervention applied in the present study was effective, as no patient develop pressure ulcers. However, the incidence of tissue lesions at the unstressed edge did not appear to be influenced by factors such as patient age (p = 0.586), gender (p = 0.674 F = 0.180), total blood protein levels (p = 0.732 ), albumin levels (0.185) and hematocrit (p = 0.669). Conclusions: In those patients that the pressure ulcers heel protectors were applied no one develops pressure ulcers during their stay in ICU. On the contrary, in those patients
    Type of Medium: Online Resource
    ISSN: 2459-3192 , 2459-3192
    URL: Article
    DOI: 10.12681/healthresj.19228
    Language: Unknown
    Publisher: National Documentation Centre (EKT)
    Publication Date: 2018
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  • 6
    Online Resource
    Online Resource
    A three-hour no hands-on practice program vs. the four-hour traditional program for laypersons
    Elsevier BV ; 2013
    In:  Resuscitation Vol. 84 ( 2013-10), p. S18-
    Details
    In: Resuscitation, Elsevier BV, Vol. 84 ( 2013-10), p. S18-
    Type of Medium: Online Resource
    ISSN: 0300-9572
    URL: Article
    DOI: 10.1016/j.resuscitation.2013.08.060
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2013
    detail.hit.zdb_id: 2010733-X
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  • 7
    Online Resource
    Online Resource
    Investigation of demographic characteristics and incidence of ocular injuries: a retrospective study
    National Documentation Centre (EKT) ; 2018
    In:  Health & Research Journal Vol. 4, No. 4 ( 2018-12-07), p. 234-
    Details
    In: Health & Research Journal, National Documentation Centre (EKT), Vol. 4, No. 4 ( 2018-12-07), p. 234-
    Abstract: Introduction: Ocular trauma is a common cause of visual reduction or loss and relates with a variety of demographic factors.Aim: Investigating the relationship of patients with eye injuries demographic data who were operated in a Public Hospital of the Attica Prefecture with place of accident, cause, classification and complications of trauma.Material and Methods: This is a retrospective study. The sample consisted of 219 patients with ocular trauma who underwent a surgical therapy. For data collection a specific registration form was used. Data analysis was performed with the statistical package Statistical Package for Social Sciences (SPSS) ver.22. Results: The relationship of gender and age of patients, with place of injury, classification and etiology of trauma was statistically significant (p 〈 0.05). The 56.7% of women reported home related injuries, mainly due to falls, while 96.8% of men reported work related injuries. The mean age of those patients injured at home was 68.15 years, while at work was 42.79 years. Statistically significant was the relationship between nationality and the place of injury and complications (p 〈 0.05). The 94% of Greek patients reported injury mainly at home, while the 25.8% of the foreigners reported injury at work, with post-traumatic endophthalmitis in 66.7% of them, mainly in rural areas. Conclusions: The investigation of relationship between the demographic data and ocular trauma is a challenge for the development of strategies prevention.
    Type of Medium: Online Resource
    ISSN: 2459-3192 , 2459-3192
    URL: Article
    DOI: 10.12681/healthresj.19298
    Language: Unknown
    Publisher: National Documentation Centre (EKT)
    Publication Date: 2018
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  • 8
    Online Resource
    Online Resource
    A retrospective study of medical emergency management in a Health Center in Greece
    National Documentation Centre (EKT) ; 2021
    In:  Health & Research Journal Vol. 7, No. 1 ( 2021-02-11), p. 17-
    Details
    In: Health & Research Journal, National Documentation Centre (EKT), Vol. 7, No. 1 ( 2021-02-11), p. 17-
    Abstract: Ιntroduction: Primary Health Centers face a plethora of emergencies of different nature and severity and it is necessary  a decision -whether or not to refer patients to the nearest hospital for further treatment and investigation- to be made.Aim: The aim of the present study was to investigate the management of emergencies in a HC of regional type near a large urban center.Material and Methods: This was a retrospective study. The data of 400 randomly selected patients admitted to the health center with acute conditions during the years 2017-2018 were recorded.Results: Out of all cases examined, 22% were rated as truly medical emergencies and 44% as not; 34% were classified as urgent; 25.9% of patients had arrived within the first hour of onset of symptoms, while 81.7% had already reached within the first 24 hours. Pain and respiratory diseases were the most common problems. In 15% of cases the patient was ambulance-transported to hospital. The proportion of ambulance referral to the nearest hospital was higher in patients with comorbidities (18.8%) than in those without (14.9%); 76% of cases were treated in accordance with evidence-based practice.Conclusions: Despite the significant progress made in treating patients in the community, it is necessary to improve management of non-emergency cases, as well as to improve the procedures for emergencies management in the HCs.
    Type of Medium: Online Resource
    ISSN: 2459-3192 , 2459-3192
    URL: Article
    DOI: 10.12681/healthresj.26095
    Language: Unknown
    Publisher: National Documentation Centre (EKT)
    Publication Date: 2021
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  • 9
    Online Resource
    Online Resource
    Causes influencing the length of stay of cardiac surgery patients in the intensive care unit
    National Documentation Centre (EKT) ; 2015
    In:  Health & Research Journal Vol. 1, No. 1 ( 2015-10-01), p. 40-
    Details
    In: Health & Research Journal, National Documentation Centre (EKT), Vol. 1, No. 1 ( 2015-10-01), p. 40-
    Abstract: Introduction: The incidence of postoperative morbidity has increased, a fact which may lead to prolonged hospitalization of the patient in the Intensive Care Unit (ICU) and generally in the hospital.Aim: The aim of the present study was to explore the complications after cardiac surgery responsible for the prolonged stay of patients in the ICU.Material and method: The studied sample consisted of 80 patients who were hospitalized in the Intensive Care Unit General Hospital of Athens from January 2013 to June 2014. For data collection a special registration form with information coming from the medical records of patients was used. Data analysis was performed by the IBM SPSS 21.0 (Statistical Package for Social Sciences).Results: Regarding to demographic characteristics Regarding the demographic characteristics and medical history of the studied sample, the majority were male (58.7%, n=47), with a mean age of 73 years and an average hospital stay of 3.3 days. The major causes of prolonged ICU stay was respiratory failure (20%, n=16), arrhythmias (17.5%, n = 14), bleeding (15%, n=12), myocardial infarction (11.3%, n=9), and pulmonary edema (10%,n=8). Τhe bivariate analysis showed statistical relationship to the level of 0,20 (p 〈 0,20) between the prolonged ICU stay and age, coronary artery disease as the cause of entry, coronary artery bypass, diabetes melitus and chronic obstructive pulmonary disease.Conclusion: Patients with a history of heart failure, diabetes or obstructive pulmonary disease seems to have a greater chance for a prolonged ICU stay after cardiac surgery. Early recognition of demographic and clinical factors that may lead to the prolonged ICU stay can provide very important information about how to improve perioperative care of the patient.
    Type of Medium: Online Resource
    ISSN: 2459-3192 , 2459-3192
    URL: Article
    DOI: 10.12681/healthresj.19279
    Language: Unknown
    Publisher: National Documentation Centre (EKT)
    Publication Date: 2015
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  • 10
    Online Resource
    Online Resource
    Prevalence of familial hypercholesterolemia in Attica region, Greece
    National Documentation Centre (EKT) ; 2021
    In:  Health & Research Journal Vol. 7, No. 1 ( 2021-02-11), p. 26-
    Details
    In: Health & Research Journal, National Documentation Centre (EKT), Vol. 7, No. 1 ( 2021-02-11), p. 26-
    Abstract: Background: Dyslipidemias are one of the major modifiable risk factors for cardiovascular disease. Familial hypercholesterolemia (FH) is the most common genetic metabolic disorder; it is estimated that around 14-34 million people worldwide have FH but only 25% of FH patients have been diagnosed. Aim: The aim of the present study was to explore the prevalence of FH in Attica region, Greece.Methods: Attica region was divided into 8 regional units. A predesigned questionnaire was used to collect demographic and clinical data. Data analysis was performed by using the Statistical Package for the Social Sciences (SPSS), ver. 20.Results: The studied sample consisted of 1578 Greek inhabitants of Attica region. The majority of the sample was women (59.9%). The mean age of the studied participants was 47.1 (±14.9) years. According to Simon Broome criteria, the probability of an FH diagnosis as unlikely is determined in 98.7% of the studied sample, probable in 0.8% of the participants or definite in 0.5% of the participants, based on this data, the prevalence of FH in Attica region, Greece is 1:200. Qualitative factors found to be associated with the onset of the disease were medication (p-value = 0.001) and hypolipidemic therapy (p-value = 0.001). The quantitative factors found to be associated with disease onset were body mass index (p-value = 0.044), and systolic (p-value = 0.001) and diastolic (p-value = 0.007) pressure.Conclusions: Based on our data, the prevalence of FH in Attica region, Greece is 1:200. Early identification of contributing factors in FH development and proper treatment is vital and reduce the risk of premature and severe atherosclerotic disease.
    Type of Medium: Online Resource
    ISSN: 2459-3192 , 2459-3192
    URL: Article
    DOI: 10.12681/healthresj.26096
    Language: Unknown
    Publisher: National Documentation Centre (EKT)
    Publication Date: 2021
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