In:
Australian Journal of Chemistry, CSIRO Publishing, Vol. 74, No. 3 ( 2021), p. 186-
Abstract:
A tetraalkyl ammonium cation and furoate anion based functionalised ionic liquid (FIL), N-methyl-N,N,N-trioctylammonium furoate ([MTOA]+[FA] –) has been synthesised and characterised using FT-IR, NMR, and UV spectroscopic techniques. The invitro antimicrobial activity of the synthesised FIL against two types of Gram-positive bacteria, namely Staphylococcus aureus and Enterobacter faecalis as well as Gram-negative bacteria, namely Escherichia coli and Pseudomonas aeruginosa was tested using a well diffusion method. Similarly, an antifungal test was done against Candida albicans. [MTOA]+[FA] – showed significant inhibitory effect against all the organisms tested as compared with the chosen standards. Antibacterial activity against gram-positive bacteria (zone of inhibition: 16 to 30mm) was found to be higher than that of Gram-negative bacteria (zone of inhibition: 11 to 19mm). Moreover, the antioxidant activity of the synthesised FIL from a ferrous ion (Fe2+) chelating assay and its scavenging activity against 1,1-diphenyl-2-picrylhydrazyl, H2O2, and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) free radical using spectrophotometric methods are reported. The FIL, [MTOA]+[FA] – showed a moderate antioxidant activity.
Type of Medium:
Online Resource
ISSN:
0004-9425
Language:
English
Publisher:
CSIRO Publishing
Publication Date:
2021
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