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  • 1
    Online Resource
    Online Resource
    Clinical evaluation of an application aid for less-invasive surfactant administration (LISA)
    BMJ ; 2021
    In:  Archives of Disease in Childhood - Fetal and Neonatal Edition Vol. 106, No. 2 ( 2021-03), p. 211-214
    Details
    In: Archives of Disease in Childhood - Fetal and Neonatal Edition, BMJ, Vol. 106, No. 2 ( 2021-03), p. 211-214
    Abstract: Less-invasive surfactant administration (LISA) is increasingly used. We investigated the feasibility of a new LISA-device (Neofact®) in neonates. Design Prospective observational pilot study with open-label LISA in two tertiary neonatal intensive care units. Patients 20 infants with a gestational age of ≥26+0/7 weeks and an indication for LISA (Respiratory Severity Score (RSS)≥5 or fraction of inspired oxygen (FiO 2 ) ≥0.30). Infants with respiratory tract malformations or unavailability of an instructed neonatologist were excluded. Main outcome measures Success of LISA, defined as laryngoscopy-confirmed intratracheal catheter position or a decrease in FiO 2 by ≥0.05 or to 0.21, accompanied by an RSS decrease of ≥2; number of attempts needed for tracheal catheterisation. Results 20/57 screened infants were enrolled. Successful application occurred in 19/20 (95%). One application failed after three attempts. No device-related adverse events occurred. The median number of attempts was 2, success rate per attempt 19/31 (61%). Conclusion LISA via Neofact® appears feasible.
    Type of Medium: Online Resource
    ISSN: 1359-2998 , 1468-2052
    URL: Article
    DOI: 10.1136/archdischild-2020-319792
    Language: English
    Publisher: BMJ
    Publication Date: 2021
    detail.hit.zdb_id: 2188490-0
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  • 2
    Online Resource
    Online Resource
    Nasal insertion depths for neonatal intubation
    BMJ ; 2020
    In:  Archives of Disease in Childhood - Fetal and Neonatal Edition Vol. 105, No. 6 ( 2020-11), p. 663-665
    Details
    In: Archives of Disease in Childhood - Fetal and Neonatal Edition, BMJ, Vol. 105, No. 6 ( 2020-11), p. 663-665
    Abstract: Data on the depth of nasal intubation in neonates are rare, although this is the preferred route in some countries. Therefore, recommendations on optimal nasal intubation depths based on gestational age (GA) and weight are desirable. Methods We determined the distances between the middle of thoracic vertebrae 2 (T2) and the tip of the endotracheal tube in 116 X-rays from nasally intubated neonates. The intubation depth (tip to nostril distance) that was documented in the digital patient’s file was then corrected for this distance to reach an optimal nasal insertion depth. Results were plotted against the infant’s GA and weight. Results GA-based and birthweight-based charts and formulas for the nasal intubation depth in infants with a GA between 24 and 43 weeks and body weight between 400 and 4500 g were created. Conclusions Generated data may help in predicting optimal insertion depths for nasal intubation in neonates.
    Type of Medium: Online Resource
    ISSN: 1359-2998 , 1468-2052
    URL: Article
    DOI: 10.1136/archdischild-2020-319140
    Language: English
    Publisher: BMJ
    Publication Date: 2020
    detail.hit.zdb_id: 2188490-0
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  • 3
    Online Resource
    Online Resource
    Catheter insertion depths in less-invasive surfactant administration
    BMJ ; 2022
    In:  Archives of Disease in Childhood - Fetal and Neonatal Edition Vol. 107, No. 2 ( 2022-03), p. 222-224
    Details
    In: Archives of Disease in Childhood - Fetal and Neonatal Edition, BMJ, Vol. 107, No. 2 ( 2022-03), p. 222-224
    Abstract: Less-invasive surfactant administration (LISA) under continuous positive airway pressure is increasingly used for the treatment of neonatal respiratory distress. Different procedures are described, but data on the optimal catheter insertion depth are sparse. Objective To generate data for recommending an optimal catheter insertion depth in LISA. Methods We examined 112 anterior–posterior chest X-rays from intubated infants and determined the carina’s vertebral projection, whenever possible. After that, distances between the middle of cervical vertebra 4 (C4) and thoracic vertebra 2 and the middle of C4 to thoracic vertebra 3, respectively, were measured. Results were plotted against infant’s weight. Results A weight-based chart and recommendations for the optimal intratracheal catheter position in infants with a body weight between 350 and 4000 g were created. Conclusions Generated data offer standardisation and may thus help to find a balance between risk of surfactant reflux and unilateral surfactant administration.
    Type of Medium: Online Resource
    ISSN: 1359-2998 , 1468-2052
    URL: Article
    DOI: 10.1136/archdischild-2021-321611
    Language: English
    Publisher: BMJ
    Publication Date: 2022
    detail.hit.zdb_id: 2188490-0
    Location Call Number Limitation Availability
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    Online Resource
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