In:
Physiological Measurement, IOP Publishing, Vol. 44, No. 4 ( 2023-04-01), p. 045001-
Abstract:
Objective. Most current algorithms for detecting atrial fibrillation (AF) rely on heart rate variability (HRV), and only a few studies analyse the variability of photopletysmography (PPG) waveform. This study aimed to compare morphological features of the PPG curve in patients with AF to those presenting a normal sinus rhythm (NSR) and evaluate their usefulness in AF detection. Approach. 10 min PPG signals were obtained from patients with persistent/paroxysmal AF and NSR. Nine morphological parameters (1/Δ T ), Pulse Width [PW], augmentation index [AI] , b/a, e/a, [b-e]/a, crest time [CT] , inflection point area [IPA], Area and five HRV parameters (heart rate [HR] , Shannon entropy [ShE], root mean square of the successive differences [RMSSD] , number of pairs of consecutive systolic peaks [ R – R ] that differ by more than 50 ms [NN50] , standard deviation of the R – R intervals [SDNN]) were calculated. Main results. Eighty subjects, including 33 with AF and 47 with NSR were recruited. In univariate analysis five morphological features (1/Δ T , p 〈 0.001; b/a, p 〈 0.001; [b-e]/a, p 〈 0.001; CT, p = 0.011 and Area, p 〈 0.001) and all HRV parameters ( p = 0.01 for HR and p 〈 0.001 for others) were significantly different between the study groups. In the stepwise multivariate model (Area under the curve [AUC] = 0.988 [0.974–1.000] ), three morphological parameters (PW, p 〈 0.001; e/a, p = 0.011; (b-e)/a, p 〈 0.001) and three of HRV parameters (ShE, p = 0.01; NN50, p 〈 0.001, HR, p = 0.01) were significant. Significance. There are significant differences between AF and NSR, PPG waveform, which are useful in AF detection algorithm. Moreover adding those features to HRV-based algorithms may improve their specificity and sensitivity.
Type of Medium:
Online Resource
ISSN:
0967-3334
,
1361-6579
DOI:
10.1088/1361-6579/acc725
Language:
Unknown
Publisher:
IOP Publishing
Publication Date:
2023
detail.hit.zdb_id:
2002076-4
SSG:
11
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